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MBX Biosciences, Inc.

MBX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001776111

In the last 90 days, MBX Biosciences, Inc. insiders filed 0 open-market purchases and 1 sale; 172 institutions reported holding it in 13F filings for Q2 2026, worth $3.06B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in MBX Biosciences, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
172
+17 vs. Q1 2026
Shares held
55.5M
+2.95M (+5.6%) vs. Q1 2026
Total value
$3.06B
+$1.49B (+95.3%) vs. Q1 2026
New holders
38
64 more added
Sold out
21
49 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 172 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 45 institutionsQ4 2024: 63 institutionsQ1 2025: 79 institutionsQ2 2025: 88 institutionsQ3 2025: 118 institutionsQ4 2025: 138 institutionsQ1 2026: 157 institutionsQ2 2026: 172 institutions
Value heldQ2 2026: $3.06B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $784.1MQ4 2024: $606.5MQ1 2025: $263.2MQ2 2025: $420.3MQ3 2025: $836.4MQ4 2025: $1.53BQ1 2026: $1.57BQ2 2026: $3.06B
Institutions holding MBX and their total value by quarter
QuarterHoldersValue
Q2 2026172$3.06B
Q1 2026157$1.57B
Q4 2025138$1.53B
Q3 2025118$836.4M
Q2 202588$420.3M
Q1 202579$263.2M
Q4 202463$606.5M
Q3 202445$784.1M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding MBX Biosciences, Inc.; share changes are against Q1 2026.

Institutions holding MBX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Susquehanna International Group, LLP26,684$1.47M0.00%+17,197+181.3%Added
Exchange Traded Concepts, LLC27,421$1.51M0.01%−6,843−20.0%Reduced
Wells Fargo & Company28,313$1.56M0.00%+17,551+163.1%Added
Deutsche Bank AG31,693$1.75M0.00%+8,743+38.1%Added
Rhumbline Advisers37,196$2.05M0.00%+3,325+9.8%Added
Creative Planning39,524$2.18M0.00%+3,554+9.9%Added
Algert Global LLC42,070$2.32M0.03%+6,050+16.8%Added
Ensign Peak Advisors, Inc42,156$2.33M0.00%+42,156New
Swiss National Bank42,900$2.37M0.00%−1,500−3.4%Reduced
Platinum Investment Management Ltd43,597$2.41M0.59%00.0%Unchanged
Alps Advisors Inc48,012$2.65M0.01%+11,462+31.4%Added
Invesco Ltd.50,678$2.80M0.00%+23,153+84.1%Added
Rhenman & Partners Asset Management AB62,000$3.42M0.32%+62,000New
Moore Capital Management, LP64,893$3.58M0.08%+64,893New
Manufacturers Life Insurance Company, The66,112$3.65M0.00%−24,522−27.1%Reduced
Boothbay Fund Management, LLC70,353$3.88M0.07%−137,696−66.2%Reduced
PFM Health Sciences, LP70,971$3.92M0.34%−923−1.3%Reduced
Affinity Asset Advisors, LLC75,000$4.14M0.20%−75,000−50.0%Reduced
Barclays PLC87,854$4.85M0.00%+76,016+642.1%Added
Prudential Financial Inc88,045$4.86M0.01%+88,045New
Bank of New York Mellon Corp88,927$4.91M0.00%+8,705+10.9%Added
Elmind Capital, LP91,000$5.02M1.26%−120,000−56.9%Reduced
TD Asset Management Inc95,598$5.28M0.00%−20,400−17.6%Reduced
Nuveen, LLC98,733$5.45M0.00%+16,941+20.7%Added
Burkehill Global Management, LP100,000$5.52M0.20%00.0%Unchanged
Two Sigma Investments, LP113,475$6.26M0.00%−1,600−1.4%Reduced
KVP Capital Advisors, LP121,524$6.71M4.92%00.0%Unchanged
JPMorgan Chase & Co139,611$7.52M0.00%−7,446−5.1%Reduced
D. E. Shaw & Co., Inc.182,767$10.1M0.01%−106,122−36.7%Reduced
Caligan Partners LP200,000$11.0M0.53%−648,590−76.4%Reduced
Vanguard Fiduciary Trust Co201,429$11.1M0.00%+31,275+18.4%Added
Polygon Management Ltd.203,543$11.2M1.83%+58,063+39.9%Added
Millennium Management LLC226,151$12.5M0.01%−338,264−59.9%Reduced
Charles Schwab Investment Management Inc233,095$12.9M0.00%+18,187+8.5%Added
Dimensional Fund Advisors LP233,700$12.9M0.00%+186,947+399.9%Added
Northern Trust Corp246,678$13.6M0.00%+36,103+17.1%Added
Morgan Stanley248,558$13.7M0.00%+216,996+687.5%Added
Schonfeld Strategic Advisors LLC248,670$13.7M0.07%+124,856+100.8%Added
Franklin Resources Inc252,665$13.9M0.00%+252,665New
Opaleye Management Inc.260,000$14.4M1.30%00.0%Unchanged
UBS Group AG272,747$15.1M0.00%−74,167−21.4%Reduced
Candriam Luxembourg S.C.A.289,893$16.0M0.07%−4,481−1.5%Reduced
Rock Springs Capital Management LP298,218$16.5M0.80%+10,251+3.6%Added
Bank of America Corp298,927$16.5M0.00%+270,177+939.7%Added
Vanguard Portfolio Management LLC346,717$19.1M0.00%+53,422+18.2%Added
EcoR1 Capital, LLC388,500$21.4M1.06%−388,500−50.0%Reduced
Marshall Wace, LLP401,885$22.2M0.02%+339,182+540.9%Added
Goldman Sachs Group Inc459,005$25.3M0.00%+1,060+0.2%Added
Soleus Capital Management, L.P.515,279$28.4M0.98%+336,382+188.0%Added
Cormorant Asset Management, LP550,000$30.4M1.56%−570,000−50.9%Reduced
TCG Crossover Management, LLC650,000$35.9M0.86%00.0%Unchanged
Braidwell LP710,880$39.2M1.45%−781,587−52.4%Reduced
Geode Capital Management, LLC773,072$42.7M0.00%+102,687+15.3%Added
Parkman Healthcare Partners LLC800,173$44.2M4.54%+1360.0%Added
Price T Rowe Associates Inc814,807$45.0M0.00%−214,200−20.8%Reduced
State Street Corp864,466$47.7M0.00%+77,258+9.8%Added
Eventide Asset Management, LLC873,492$48.2M0.64%−16,508−1.9%Reduced
Woodline Partners LP900,092$49.7M0.15%+290.0%Added
Kynam Capital Management, LP934,799$51.6M2.85%00.0%Unchanged
Driehaus Capital Management LLC1,056,579$58.3M0.34%+38,367+3.8%Added
Aaron Wealth Advisors1,167,799$64.5M3.27%−3770.0%Reduced
Vanguard Capital Management LLC1,477,388$81.6M0.00%−2040.0%Reduced
Polar Capital Holdings Plc1,608,514$88.8M0.25%−13,672−0.8%Reduced
Deep Track Capital, LP1,732,569$95.6M1.41%−1,025,000−37.2%Reduced
NVP Associates, LLC2,136,335$117.9M35.93%00.0%Unchanged
Paradigm Biocapital Advisors LP2,508,015$138.4M2.59%+2,508,015New
BlackRock, Inc.3,323,672$183.5M0.00%+382,266+13.0%Added
OrbiMed Advisors LLC3,428,736$189.3M3.58%−209,151−5.7%Reduced
NEA Management Company, LLC3,614,486$199.5M12.56%00.0%Unchanged
Wellington Management Group LLP4,977,523$274.8M0.05%+1,785,699+55.9%Added
FMR LLC5,322,885$293.8M0.01%+2,386,201+81.3%Added
Frazier Life Sciences Management, L.P.6,652,013$367.2M8.00%00.0%Unchanged
Citadel Advisors LLC0$00.00%−932,833−100.0%Sold out
StemPoint Capital LP0$00.00%−499,469−100.0%Sold out
Squarepoint Ops LLC0$00.00%−97,215−100.0%Sold out
Victory Capital Management Inc0$00.00%−71,028−100.0%Sold out
Schroder Investment Management Group0$00.00%−57,322−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−28,087−100.0%Sold out
Swiss Life Asset Management Ltd0$00.00%−12,130−100.0%Sold out
Engineers Gate Manager LP0$00.00%−17,380−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−17,187−100.0%Sold out
Jump Financial, LLC0$00.00%−12,700−100.0%Sold out
Verition Fund Management LLC0$00.00%−10,222−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−10,155−100.0%Sold out
Acadian Asset Management LLC0$00.00%−8,823−100.0%Sold out
Brinker Capital Investments, LLC0$00.00%−7,951−100.0%Sold out
Bridgeway Capital Management, LLC0$00.00%−7,500−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−5,600−100.0%Sold out
Cygnus Capital Advisors, LLC0$00.00%−1,800−100.0%Sold out
Versant Capital Management, Inc0$00.00%−24−100.0%Sold out
MAI Capital Management0$00.00%−7−100.0%Sold out
True Wealth Design, LLC0$00.00%−2−100.0%Sold out
IFP Advisors, Inc0$00.00%−1−100.0%Sold out
Janus Henderson Group PLC––––Not filed
CWM, LLC––––Not filed