MBX Biosciences, Inc.
MBX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001776111
In the last 90 days, MBX Biosciences, Inc. insiders filed 0 open-market purchases and 1 sale; 172 institutions reported holding it in 13F filings for Q2 2026, worth $3.06B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in MBX Biosciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 157
- +21 vs. Q4 2025
- Shares held
- 52.5M
- +5.92M (+12.7%) vs. Q4 2025
- Total value
- $1.57B
- +$98.0M (+6.7%) vs. Q4 2025
- New holders
- 39
- 43 more added
- Sold out
- 18
- 47 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 172 | $3.06B |
| Q1 2026 | 157 | $1.57B |
| Q4 2025 | 138 | $1.53B |
| Q3 2025 | 118 | $836.4M |
| Q2 2025 | 88 | $420.3M |
| Q1 2025 | 79 | $263.2M |
| Q4 2024 | 63 | $606.5M |
| Q3 2024 | 45 | $784.1M |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding MBX Biosciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Marshall Wace, LLP | 62,703 | $1.87M | 0.00% | +62,703 | New |
| Victory Capital Management Inc | 71,028 | $2.12M | 0.00% | +71,028 | New |
| PFM Health Sciences, LP | 71,894 | $2.15M | 0.23% | −7,416−9.4% | Reduced |
| Bank of New York Mellon Corp | 80,222 | $2.39M | 0.00% | +4,960+6.6% | Added |
| Nuveen, LLC | 81,792 | $2.44M | 0.00% | +6,227+8.2% | Added |
| Manufacturers Life Insurance Company, The | 90,634 | $2.71M | 0.00% | +21,083+30.3% | Added |
| Squarepoint Ops LLC | 97,215 | $2.90M | 0.01% | +50,513+108.2% | Added |
| Burkehill Global Management, LP | 100,000 | $2.98M | 0.15% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 115,075 | $3.43M | 0.00% | −23,496−17.0% | Reduced |
| TD Asset Management Inc | 115,998 | $3.46M | 0.00% | +14,548+14.3% | Added |
| KVP Capital Advisors, LP | 121,524 | $3.63M | 2.71% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 123,814 | $3.70M | 0.03% | −43,311−25.9% | Reduced |
| JPMorgan Chase & Co | 147,057 | $3.96M | 0.00% | +132,412+904.1% | Added |
| Polygon Management Ltd. | 145,480 | $4.34M | 0.85% | +2,153+1.5% | Added |
| Affinity Asset Advisors, LLC | 150,000 | $4.48M | 0.26% | −100,000−40.0% | Reduced |
| Goelzer Investment Management, Inc. | 164,172 | $4.90M | 0.24% | −57,500−25.9% | Reduced |
| Vanguard Fiduciary Trust Co | 170,154 | $5.08M | 0.00% | +170,154 | New |
| DAFNA Capital Management LLC | 175,465 | $5.24M | 1.19% | +10,200+6.2% | Added |
| Soleus Capital Management, L.P. | 178,897 | $5.34M | 0.22% | −230,003−56.2% | Reduced |
| Boothbay Fund Management, LLC | 208,049 | $6.21M | 0.15% | +208,049 | New |
| Northern Trust Corp | 210,575 | $6.29M | 0.00% | +19,694+10.3% | Added |
| Elmind Capital, LP | 211,000 | $6.30M | 1.79% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 214,908 | $6.42M | 0.00% | −7,272−3.3% | Reduced |
| Opaleye Management Inc. | 260,000 | $7.76M | 1.02% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 287,967 | $8.60M | 0.51% | +5,343+1.9% | Added |
| D. E. Shaw & Co., Inc. | 288,889 | $8.62M | 0.01% | −382,949−57.0% | Reduced |
| Vanguard Portfolio Management LLC | 293,295 | $8.75M | 0.00% | +293,295 | New |
| Candriam Luxembourg S.C.A. | 294,374 | $8.79M | 0.05% | +294,374 | New |
| UBS Group AG | 346,914 | $10.4M | 0.00% | +65,702+23.4% | Added |
| Goldman Sachs Group Inc | 457,945 | $13.7M | 0.00% | +126,007+38.0% | Added |
| StemPoint Capital LP | 499,469 | $14.9M | 2.87% | +420,916+535.8% | Added |
| Millennium Management LLC | 564,415 | $16.8M | 0.01% | +102,366+22.2% | Added |
| TCG Crossover Management, LLC | 650,000 | $19.4M | 0.56% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 670,385 | $20.0M | 0.00% | +20,994+3.2% | Added |
| EcoR1 Capital, LLC | 777,000 | $23.2M | 0.99% | −1,346,604−63.4% | Reduced |
| State Street Corp | 787,208 | $23.5M | 0.00% | +114,468+17.0% | Added |
| Parkman Healthcare Partners LLC | 800,037 | $23.9M | 2.48% | −85,602−9.7% | Reduced |
| Caligan Partners LP | 848,590 | $25.3M | 1.79% | +848,590 | New |
| Eventide Asset Management, LLC | 890,000 | $26.6M | 0.44% | 00.0% | Unchanged |
| Woodline Partners LP | 900,063 | $26.9M | 0.10% | −100,000−10.0% | Reduced |
| Citadel Advisors LLC | 932,833 | $27.8M | 0.02% | +122,976+15.2% | Added |
| Kynam Capital Management, LP | 934,799 | $27.9M | 1.77% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 1,018,212 | $30.4M | 0.22% | −389,947−27.7% | Reduced |
| Price T Rowe Associates Inc | 1,029,007 | $30.7M | 0.00% | +188,501+22.4% | Added |
| Cormorant Asset Management, LP | 1,120,000 | $33.4M | 1.69% | 00.0% | Unchanged |
| Aaron Wealth Advisors | 1,168,176 | $34.9M | 2.01% | +1,098,176+1,568.8% | Added |
| Vanguard Capital Management LLC | 1,477,592 | $44.1M | 0.00% | +1,477,592 | New |
| Braidwell LP | 1,492,467 | $44.6M | 1.49% | +473,867+46.5% | Added |
| Polar Capital Holdings Plc | 1,622,186 | $48.4M | 0.21% | +1,622,186 | New |
| NVP Associates, LLC | 2,136,335 | $63.8M | 36.20% | 00.0% | Unchanged |
| Deep Track Capital, LP | 2,757,569 | $82.3M | 1.70% | −492,221−15.1% | Reduced |
| FMR LLC | 2,936,684 | $87.7M | 0.00% | +2,920,938+18,550.3% | Added |
| BlackRock, Inc. | 2,941,406 | $87.8M | 0.00% | +21,650+0.7% | Added |
| Wellington Management Group LLP | 3,191,824 | $95.3M | 0.02% | −158,137−4.7% | Reduced |
| NEA Management Company, LLC | 3,614,486 | $107.9M | 6.13% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 3,637,887 | $108.6M | 2.47% | −297,316−7.6% | Reduced |
| Frazier Life Sciences Management, L.P. | 6,652,013 | $198.6M | 5.11% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −680,609−100.0% | Sold out |
| Trails Edge Capital Partners, LP | 0 | $0 | 0.00% | −315,158−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −119,726−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −86,581−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −32,644−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −25,663−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −24,268−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −23,820−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −19,295−100.0% | Sold out |
| Seven Fleet Capital Management LP | 0 | $0 | 0.00% | −18,200−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −11,254−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −8,113−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −7,187−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −6,463−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −895−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −265−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −150−100.0% | Sold out |
| SBI Securities Co., Ltd. | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |