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MBX Biosciences, Inc.

MBX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001776111

In the last 90 days, MBX Biosciences, Inc. insiders filed 0 open-market purchases and 1 sale; 172 institutions reported holding it in 13F filings for Q2 2026, worth $3.06B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in MBX Biosciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
138
+20 vs. Q3 2025
Shares held
48.4M
+638.7K (+1.3%) vs. Q3 2025
Total value
$1.53B
+$690.9M (+82.6%) vs. Q3 2025
New holders
45
53 more added
Sold out
25
25 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 138 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 45 institutionsQ4 2024: 63 institutionsQ1 2025: 79 institutionsQ2 2025: 88 institutionsQ3 2025: 118 institutionsQ4 2025: 138 institutionsQ1 2026: 157 institutionsQ2 2026: 172 institutions
Value heldQ4 2025: $1.53B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $784.1MQ4 2024: $606.5MQ1 2025: $263.2MQ2 2025: $420.3MQ3 2025: $836.4MQ4 2025: $1.53BQ1 2026: $1.57BQ2 2026: $3.06B
Institutions holding MBX and their total value by quarter
QuarterHoldersValue
Q2 2026172$3.06B
Q1 2026157$1.57B
Q4 2025138$1.53B
Q3 2025118$836.4M
Q2 202588$420.3M
Q1 202579$263.2M
Q4 202463$606.5M
Q3 202445$784.1M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding MBX Biosciences, Inc.; share changes are against Q3 2025.

Institutions holding MBX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
IFP Advisors, Inc1$320.00%+1New
True Wealth Design, LLC2$640.00%+2New
SBI Securities Co., Ltd.9$2840.00%+9New
Farther Finance Advisors, LLC10$3150.00%−318−97.0%Reduced
Essential Partners LLC15$4730.00%+13+650.0%Added
Global Retirement Partners, LLC19$5990.00%+19New
Rothschild Investment LLC24$7570.00%+4+20.0%Added
EverSource Wealth Advisors, LLC25$7890.00%+2+8.7%Added
Cornerstone Financial Management LLC34$1.07K0.00%+34New
Allworth Financial LP52$1.64K0.00%+27+108.0%Added
Parallel Advisors, LLC61$1.92K0.00%00.0%Unchanged
Jones Financial Companies LLLP80$2.52K0.00%+80New
UBS Asset Management Americas Inc100$3.15K0.00%+100New
UMA Financial Services, Inc.109$3.44K0.00%00.0%Unchanged
Daiwa Securities Group Inc.150$5.00K0.00%+150New
Signaturefd, LLC179$5.65K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.196$6.18K0.00%−56−22.2%Reduced
Aster Capital Management (DIFC) Ltd265$8.36K0.00%+265New
GAMMA Investing LLC299$9.43K0.00%00.0%Unchanged
US Bancorp312$9.84K0.00%−25−7.4%Reduced
STRS Ohio700$22.1K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.882$27.8K0.00%+882New
Amalgamated Bank895$28.0K0.00%+511+133.1%Added
Royal Bank of Canada1,532$49.0K0.00%+572+59.6%Added
Nisa Investment Advisors, LLC1,592$50.2K0.00%00.0%Unchanged
Sterling Capital Management LLC1,641$51.8K0.00%+583+55.1%Added
California State Teachers Retirement System1,754$55.3K0.00%+689+64.7%Added
CWM, LLC1,784$56.0K0.00%+400+28.9%Added
Cygnus Capital Advisors, LLC1,800$57.0K0.04%+1,800New
Mirae Asset Global Investments Co., Ltd.2,182$68.8K0.00%+2,182New
Ameritas Investment Partners, Inc.2,312$72.9K0.00%+1,135+96.4%Added
Legal & General Group Plc2,539$80.1K0.00%+1,211+91.2%Added
Russell Investments Group, Ltd.2,856$90.1K0.00%+1,375+92.8%Added
Rockefeller Capital Management L.P.3,000$94.6K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,416$107.7K0.00%+2,149+169.6%Added
New York State Common Retirement Fund4,300$135.6K0.00%00.0%Unchanged
SG Americas Securities, LLC4,765$150.0K0.00%+4,765New
Axq Capital, LP6,463$203.8K0.05%+6,463New
BNP Paribas Arbitrage, SA6,784$214.0K0.00%+3,888+134.3%Added
Intech Investment Management LLC6,858$216.3K0.00%+6,858New
Los Angeles Capital Management LLC10,360$225.7K0.00%+10,360New
ProShare Advisors LLC7,187$226.7K0.00%+7,187New
Police & Firemen's Retirement System of New Jersey7,520$237.2K0.00%+3,011+66.8%Added
SEI Investments Co7,657$241.5K0.00%+7,657New
Rafferty Asset Management, LLC8,113$255.9K0.00%+8,113New
Virtus Investment Advisers, Inc.8,910$281.0K0.08%−1,704−16.1%Reduced
Simplex Trading, LLC8,925$281.5K0.01%+8,925New
Profund Advisors LLC9,214$290.6K0.01%+9,214New
Group One Trading, L.P.9,428$297.4K0.01%+9,428New
Bridgeway Capital Management, LLC10,000$315.4K0.01%−4,200−29.6%Reduced
Graham Capital Management, L.P.11,254$355.0K0.01%+11,254New
Canada Pension Plan Investment Board11,600$365.9K0.00%+11,600New
American Century Companies Inc12,236$385.9K0.00%+12,236New
Mirae Asset Global ETFs Holdings Ltd.13,258$418.2K0.00%+6,138+86.2%Added
JPMorgan Chase & Co14,645$461.9K0.00%+8,470+137.2%Added
China Universal Asset Management Co., Ltd.15,317$483.1K0.04%+10,317+206.3%Added
FMR LLC15,746$496.6K0.00%−53,230−77.2%Reduced
MetLife Investment Management16,018$505.2K0.00%+5,000+45.4%Added
Citigroup Inc16,391$517.0K0.00%+16,213+9,108.4%Added
Seven Fleet Capital Management LP18,200$574.0K0.39%+18,200New
Koa Wealth Management, LLC18,413$580.7K0.40%−8,300−31.1%Reduced
Gsa Capital Partners LLP19,295$609.0K0.05%+19,295New
Deutsche Bank AG20,027$631.7K0.00%+9,104+83.3%Added
XTX Topco Ltd20,139$635.2K0.02%−18,239−47.5%Reduced
Invesco Ltd.21,203$668.7K0.00%+9,415+79.9%Added
Cerity Partners LLC21,323$672.5K0.00%+21,323New
Qube Research & Technologies Ltd23,213$732.1K0.00%+23,213New
Fox Run Management, L.L.C.23,820$751.3K0.12%+23,820New
Trexquant Investment LP24,268$765.4K0.01%+24,268New
Brevan Howard Capital Management LP25,663$809.4K0.02%+25,663New
Alliancebernstein L.P.27,900$880.0K0.00%+17,400+165.7%Added
AQR Capital Management LLC31,409$990.6K0.00%+15,645+99.2%Added
Wells Fargo & Company31,931$1.01M0.00%+20,176+171.6%Added
Renaissance Technologies LLC32,644$1.03M0.00%+32,644New
Rhumbline Advisers33,420$1.05M0.00%+11,599+53.2%Added
Creative Planning33,651$1.06M0.00%+4,919+17.1%Added
Alps Advisors Inc36,872$1.16M0.01%+20,032+119.0%Added
Bank of America Corp37,894$1.20M0.00%+11,278+42.4%Added
Platinum Investment Management Ltd43,597$1.38M0.32%−25,831−37.2%Reduced
Squarepoint Ops LLC46,702$1.47M0.00%+46,702New
Acadian Asset Management LLC48,614$1.53M0.00%+43,605+870.5%Added
Barclays PLC52,691$1.66M0.00%+31,065+143.6%Added
ExodusPoint Capital Management, LP57,005$1.80M0.02%−42,995−43.0%Reduced
Verition Fund Management LLC57,575$1.82M0.01%+57,575New
Morgan Stanley59,026$1.86M0.00%+14,158+31.6%Added
Manufacturers Life Insurance Company, The69,551$2.15M0.00%+1,175+1.7%Added
Aaron Wealth Advisors70,000$2.21M0.12%+20,000+40.0%Added
Schroder Investment Management Group73,736$2.28M0.00%−10,030−12.0%Reduced
Bank of New York Mellon Corp75,262$2.37M0.00%+27,527+57.7%Added
Nuveen, LLC75,565$2.38M0.00%+53,422+241.3%Added
Susquehanna International Group, LLP76,528$2.41M0.00%+76,528New
Advisor Group Holdings, Inc.77,601$2.45M0.00%+77,601New
StemPoint Capital LP78,553$2.48M0.43%+3,553+4.7%Added
PFM Health Sciences, LP79,310$2.50M0.25%−142,195−64.2%Reduced
Jane Street Group, LLC86,581$2.73M0.00%+86,581New
Burkehill Global Management, LP100,000$3.15M0.21%00.0%Unchanged
TD Asset Management Inc101,450$3.20M0.00%−17,342−14.6%Reduced
Balyasny Asset Management LLC119,726$3.78M0.01%+94,085+366.9%Added
KVP Capital Advisors, LP121,524$3.83M3.96%+121,524New
Two Sigma Investments, LP138,571$4.37M0.01%+124,984+919.9%Added