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Janux Therapeutics, Inc.

JANX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001817713

No open-market purchases or sales by Janux Therapeutics, Inc. insiders were filed in the last 90 days; 197 institutions reported holding it in 13F filings for Q2 2026, worth $933.4M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Janux Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
176
+6 vs. Q3 2025
Shares held
62.2M
−2.63M (−4.1%) vs. Q3 2025
Total value
$860.0M
−$725.4M (−45.8%) vs. Q3 2025
New holders
44
69 more added
Sold out
38
41 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting JANX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 176 institutions
Q1 2021: 0 institutionsQ2 2021: 30 institutionsQ3 2021: 45 institutionsQ4 2021: 46 institutionsQ1 2022: 47 institutionsQ2 2022: 44 institutionsQ3 2022: 49 institutionsQ4 2022: 50 institutionsQ1 2023: 48 institutionsQ2 2023: 54 institutionsQ3 2023: 57 institutionsQ4 2023: 64 institutionsQ1 2024: 121 institutionsQ2 2024: 155 institutionsQ3 2024: 160 institutionsQ4 2024: 216 institutionsQ1 2025: 181 institutionsQ2 2025: 174 institutionsQ3 2025: 174 institutionsQ4 2025: 176 institutionsQ1 2026: 190 institutionsQ2 2026: 197 institutions
Value heldQ4 2025: $860.0M
Q1 2021: $0Q2 2021: $614.5MQ3 2021: $571.2MQ4 2021: $541.6MQ1 2022: $407.1MQ2 2022: $353.0MQ3 2022: $400.3MQ4 2022: $381.3MQ1 2023: $369.5MQ2 2023: $362.1MQ3 2023: $354.0MQ4 2023: $359.5MQ1 2024: $1.59BQ2 2024: $1.87BQ3 2024: $2.07BQ4 2024: $3.43BQ1 2025: $1.81BQ2 2025: $1.51BQ3 2025: $1.59BQ4 2025: $860.0MQ1 2026: $827.8MQ2 2026: $933.4M
Institutions holding JANX and their total value by quarter
QuarterHoldersValue
Q2 2026197$933.4M
Q1 2026190$827.8M
Q4 2025176$860.0M
Q3 2025174$1.59B
Q2 2025174$1.51B
Q1 2025181$1.81B
Q4 2024216$3.43B
Q3 2024160$2.07B
Q2 2024155$1.87B
Q1 2024121$1.59B
Q4 202364$359.5M
Q3 202357$354.0M
Q2 202354$362.1M
Q1 202348$369.5M
Q4 202250$381.3M
Q3 202249$400.3M
Q2 202244$353.0M
Q1 202247$407.1M
Q4 202146$541.6M
Q3 202145$571.2M
Q2 202130$614.5M
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Janux Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding JANX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,189,693$154.4M1.58%00.0%Unchanged
Janus Henderson Group PLC5,350,453$73.9M0.03%+649,341+13.8%Added
BlackRock, Inc.4,080,200$56.3M0.00%+349,206+9.4%Added
State Street Corp3,853,951$53.2M0.00%+1,962,486+103.8%Added
FMR LLC3,512,384$48.5M0.00%−5,543,678−61.2%Reduced
Vanguard Group Inc2,906,386$40.1M0.00%+489,282+20.2%Added
Prosight Management, LP2,392,523$33.0M6.82%+1,527,173+176.5%Added
OrbiMed Advisors LLC1,954,426$27.0M0.55%+188,326+10.7%Added
TCG Crossover Management, LLC1,789,617$24.7M0.82%+1,789,617New
Wellington Management Group LLP1,610,186$22.2M0.00%+908,582+129.5%Added
Alyeska Investment Group, L.P.1,301,089$18.0M0.05%+876,244+206.3%Added
Geode Capital Management, LLC1,113,582$15.4M0.00%+29,718+2.7%Added
Citadel Advisors LLC1,104,144$15.2M0.01%+301,360+37.5%Added
Goldman Sachs Group Inc1,073,656$14.8M0.00%+418,548+63.9%Added
Woodline Partners LP1,027,221$14.2M0.05%+2830.0%Added
Logos Global Management LP1,000,000$13.8M0.92%+65,000+7.0%Added
Point72 Asset Management, L.P.961,819$13.3M0.02%−748,381−43.8%Reduced
Readystate Asset Management LP885,895$12.2M0.54%−74,484−7.8%Reduced
Balyasny Asset Management LLC885,551$12.2M0.02%+885,551New
Price T Rowe Associates Inc744,466$10.3M0.00%−521,090−41.2%Reduced
Bank of America Corp738,330$10.2M0.00%+244,878+49.6%Added
Cormorant Asset Management, LP650,000$8.97M0.51%−200,000−23.5%Reduced
Morgan Stanley618,385$8.53M0.00%+122,750+24.8%Added
UBS Group AG590,060$8.14M0.00%+199,703+51.2%Added
Jane Street Group, LLC540,233$7.46M0.01%+458,911+564.3%Added
Two Sigma Investments, LP471,009$6.50M0.01%+367,533+355.2%Added
Adage Capital Partners GP, L.L.C.400,000$5.52M0.01%−2,375,000−85.6%Reduced
Squarepoint Ops LLC390,952$5.40M0.01%+324,791+490.9%Added
Charles Schwab Investment Management Inc390,506$5.39M0.00%+35,962+10.1%Added
Franklin Resources Inc385,301$5.32M0.00%−502,454−56.6%Reduced
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.376,496$5.20M0.46%00.0%Unchanged
University of Wisconsin Foundation362,000$5.00M4.20%+362,000New
Rock Springs Capital Management LP358,798$4.95M0.25%+148,432+70.6%Added
Northern Trust Corp340,406$4.70M0.00%−13,707−3.9%Reduced
Walleye Capital LLC323,017$4.46M0.03%+287,196+801.8%Added
Millennium Management LLC289,808$4.00M0.00%+189,163+188.0%Added
Caption Management, LLC272,500$3.76M0.17%+182,500+202.8%Added
Pictet Asset Management Holding SA272,251$3.76M0.00%−322,580−54.2%Reduced
Schroder Investment Management Group267,051$3.69M0.00%−31,827−10.6%Reduced
ADAR1 Capital Management, LLC245,452$3.39M0.25%−105,580−30.1%Reduced
Rhenman & Partners Asset Management AB225,377$3.11M0.29%+125,250+125.1%Added
Dimensional Fund Advisors LP224,294$3.10M0.00%−16,337−6.8%Reduced
Barclays PLC221,233$3.05M0.00%+77,209+53.6%Added
Qube Research & Technologies Ltd216,005$2.98M0.00%+105,156+94.9%Added
Algert Global LLC183,367$2.53M0.04%+95,150+107.9%Added
Rafferty Asset Management, LLC175,248$2.42M0.01%+99,052+130.0%Added
JPMorgan Chase & Co170,509$2.35M0.00%−38,674−18.5%Reduced
Trexquant Investment LP170,484$2.35M0.02%+157,267+1,189.9%Added
ExodusPoint Capital Management, LP161,548$2.23M0.02%+161,548New
XTX Topco Ltd161,427$2.23M0.06%+161,427New
Sphera Funds Management Ltd.157,840$2.18M0.46%+72,000+83.9%Added
DekaBank Deutsche Girozentrale49,500$2.04M0.00%00.0%Unchanged
Bank of New York Mellon Corp122,066$1.68M0.00%+1,594+1.3%Added
Hudson Bay Capital Management LP110,000$1.52M0.01%+60,000+120.0%Added
Two Sigma Advisers, LP104,100$1.44M0.00%+104,100New
Blue Owl Capital Holdings LP100,000$1.38M0.43%+100,000New
Jump Financial, LLC96,684$1.33M0.02%−83,016−46.2%Reduced
Nuveen, LLC96,416$1.33M0.00%+787+0.8%Added
Deep Track Capital, LP89,589$1.24M0.03%+89,589New
SG Americas Securities, LLC79,817$1.10M0.00%+50,802+175.1%Added
Tudor Investment Corp Et Al79,158$1.09M0.01%−19,398−19.7%Reduced
Swiss National Bank77,100$1.06M0.00%+2,500+3.4%Added
Nomura Asset Management International Inc.76,601$1.06M0.00%+76,601New
UBS Asset Management Americas Inc75,498$1.04M0.00%+9,173+13.8%Added
Man Group plc64,512$890.3K0.00%+64,512New
Profund Advisors LLC64,022$883.5K0.03%+47,584+289.5%Added
HRT Financial LP63,544$876.0K0.00%+63,544New
Twinbeech Capital LP58,810$811.6K0.06%+58,810New
Dark Forest Capital Management LP57,363$791.6K0.04%+33,716+142.6%Added
Congress Asset Management Co57,342$791.3K0.01%+1,569+2.8%Added
Headlands Technologies LLC56,497$779.7K0.07%+56,497New
Aquatic Capital Management LLC52,421$723.4K0.02%+52,421New
Rhumbline Advisers52,361$722.6K0.00%−5,283−9.2%Reduced
Wells Fargo & Company47,919$661.3K0.00%+19,401+68.0%Added
Raiffeisen Bank International AG46,000$636.2K0.01%+22,000+91.7%Added
Schonfeld Strategic Advisors LLC45,453$627.3K0.00%+45,453New
Legal & General Group Plc43,467$599.8K0.00%+5,551+14.6%Added
Freestone Grove Partners LP41,806$576.9K0.00%+41,806New
HighVista Strategies LLC41,443$571.9K0.15%−13,807−25.0%Reduced
Teachers Retirement System of the State of Kentucky38,875$536.0K0.00%+38,875New
State of Wisconsin Investment Board38,487$531.1K0.00%+4,967+14.8%Added
NEOS Investment Management LLC37,647$519.5K0.00%−2,704−6.7%Reduced
California State Teachers Retirement System37,320$515.0K0.00%+173+0.5%Added
Tema ETFs LLC37,092$511.9K0.04%−3,259−8.1%Reduced
Manufacturers Life Insurance Company, The36,555$505.0K0.00%−28,433−43.8%Reduced
Alliancebernstein L.P.35,590$491.1K0.00%00.0%Unchanged
Susquehanna International Group, LLP35,237$486.3K0.00%−133,904−79.2%Reduced
Quadrature Capital Ltd33,002$455.4K0.00%+6,141+22.9%Added
D. E. Shaw & Co., Inc.32,707$451.4K0.00%+32,707New
Deutsche Bank AG32,170$443.9K0.00%−3,988−11.0%Reduced
Winton Group Ltd31,800$438.8K0.02%+31,800New
Mirae Asset Global ETFs Holdings Ltd.30,148$416.3K0.00%+7,784+34.8%Added
Invesco Ltd.28,322$390.8K0.00%+3,853+15.7%Added
Atom Investors LP27,942$385.6K0.03%+27,942New
American Century Companies Inc27,691$382.1K0.00%+8,738+46.1%Added
Rangeley Capital, LLC25,414$350.7K0.30%+25,414New
Lester Murray Antman dba SimplyRich24,315$335.0K0.09%00.0%Unchanged
Citigroup Inc24,218$334.2K0.00%+18,703+339.1%Added
Quantinno Capital Management LP24,218$334.2K0.00%+24,218New
MetLife Investment Management23,876$329.5K0.00%00.0%Unchanged