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Iovance Biotherapeutics, Inc.

IOVA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001425205

No open-market purchases or sales by Iovance Biotherapeutics, Inc. insiders were filed in the last 90 days; 293 institutions reported holding it in 13F filings for Q2 2026, worth $1.19B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Iovance Biotherapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
263
+15 vs. Q3 2025
Shares held
261.6M
+48.6M (+22.8%) vs. Q3 2025
Total value
$713.7M
+$251.6M (+54.4%) vs. Q3 2025
New holders
51
103 more added
Sold out
36
63 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IOVA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 263 institutions
Q1 2021: 252 institutionsQ2 2021: 234 institutionsQ3 2021: 244 institutionsQ4 2021: 246 institutionsQ1 2022: 248 institutionsQ2 2022: 238 institutionsQ3 2022: 242 institutionsQ4 2022: 218 institutionsQ1 2023: 230 institutionsQ2 2023: 219 institutionsQ3 2023: 228 institutionsQ4 2023: 236 institutionsQ1 2024: 273 institutionsQ2 2024: 295 institutionsQ3 2024: 286 institutionsQ4 2024: 302 institutionsQ1 2025: 303 institutionsQ2 2025: 255 institutionsQ3 2025: 253 institutionsQ4 2025: 263 institutionsQ1 2026: 286 institutionsQ2 2026: 293 institutions
Value heldQ4 2025: $713.7M
Q1 2021: $4.98BQ2 2021: $4.22BQ3 2021: $3.88BQ4 2021: $2.96BQ1 2022: $2.60BQ2 2022: $1.75BQ3 2022: $1.48BQ4 2022: $1.11BQ1 2023: $1.25BQ2 2023: $1.44BQ3 2023: $970.0MQ4 2023: $1.69BQ1 2024: $3.22BQ2 2024: $1.86BQ3 2024: $2.21BQ4 2024: $1.79BQ1 2025: $798.9MQ2 2025: $379.3MQ3 2025: $462.3MQ4 2025: $713.7MQ1 2026: $943.8MQ2 2026: $1.19B
Institutions holding IOVA and their total value by quarter
QuarterHoldersValue
Q2 2026293$1.19B
Q1 2026286$943.8M
Q4 2025263$713.7M
Q3 2025253$462.3M
Q2 2025255$379.3M
Q1 2025303$798.9M
Q4 2024302$1.79B
Q3 2024286$2.21B
Q2 2024295$1.86B
Q1 2024273$3.22B
Q4 2023236$1.69B
Q3 2023228$970.0M
Q2 2023219$1.44B
Q1 2023230$1.25B
Q4 2022218$1.11B
Q3 2022242$1.48B
Q2 2022238$1.75B
Q1 2022248$2.60B
Q4 2021246$2.96B
Q3 2021244$3.88B
Q2 2021234$4.22B
Q1 2021252$4.98B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Iovance Biotherapeutics, Inc.; share changes are against Q3 2025.

Institutions holding IOVA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Squarepoint Ops LLC25,001$68.3K0.00%−18,757−42.9%Reduced
Ameritas Investment Partners, Inc.25,414$69.4K0.00%+3,600+16.5%Added
Flputnam Investment Management Co25,950$70.8K0.00%+5,661+27.9%Added
Farallon Capital Management, L.L.C.26,000$71.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA26,787$73.1K0.00%−27,566−50.7%Reduced
Pictet Asset Management Holding SA27,122$74.0K0.00%00.0%Unchanged
DRW Securities, LLC28,558$78.0K0.01%+28,558New
First Manhattan Co28,998$79.2K0.00%−25,302−46.6%Reduced
Grimes & Company, Inc.29,338$80.1K0.00%−14,007−32.3%Reduced
Cim Investment Mangement Inc29,423$80.3K0.02%00.0%Unchanged
Optiver Holding B.V.29,568$80.7K0.00%+28,625+3,035.5%Added
Intrepid Family Office LLC30,000$81.9K0.08%−10,000−25.0%Reduced
FMR LLC31,073$84.8K0.00%−12,508−28.7%Reduced
Gould Asset Management LLC31,735$86.6K0.02%+20,000+170.4%Added
Universal- Beteiligungs- und Servicegesellschaft mbH33,357$91.1K0.00%+20,758+164.8%Added
Penbrook Management LLC33,945$92.7K0.06%+33,945New
Diversify Wealth Management, LLC40,000$94.0K0.00%00.0%Unchanged
R Squared Ltd34,533$94.3K0.04%+18,490+115.3%Added
Carnegie Capital Asset Management, LLC36,000$98.3K0.00%−1,000−2.7%Reduced
Cambridge Investment Research Advisors, Inc.37,893$103.0K0.00%−17,364−31.4%Reduced
Delaney Dennis R38,000$103.7K0.05%00.0%Unchanged
Traphagen Investment Advisors LLC38,962$106.4K0.01%00.0%Unchanged
Victory Capital Management Inc38,993$106.5K0.00%+5,287+15.7%Added
Neuberger Berman Group LLC39,072$106.7K0.00%+5,605+16.7%Added
Chicago Partners Investment Group LLC40,589$107.2K0.00%+90.0%Added
Great West Life Assurance Co40,958$112.0K0.00%+6,933+20.4%Added
LMR Partners LLP41,211$112.5K0.00%00.0%Unchanged
Teacher Retirement System of Texas45,047$123.0K0.00%−19,739−30.5%Reduced
Captrust Financial Advisors46,812$127.8K0.00%+5,563+13.5%Added
Assenagon Asset Management S.A.46,842$127.9K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd47,277$129.1K0.03%+41,047+658.9%Added
National Asset Management, Inc.48,000$131.0K0.01%+6,000+14.3%Added
Zurcher Kantonalbank (Zurich Cantonalbank)49,914$136.3K0.00%+15,992+47.1%Added
Rockefeller Capital Management L.P.50,726$138.5K0.00%+33,091+187.6%Added
The PNC Financial Services Group, Inc.50,848$138.8K0.00%−208−0.4%Reduced
Commonwealth Equity Services, LLC51,499$140.6K0.00%−151−0.3%Reduced
Centurion Wealth Management LLC52,384$143.0K0.03%−700−1.3%Reduced
TD Asset Management Inc53,452$145.9K0.00%−86,426−61.8%Reduced
Voya Investment Management LLC53,477$146.0K0.00%+6,300+13.4%Added
Man Group plc54,521$148.8K0.00%+3,118+6.1%Added
SG Americas Securities, LLC55,389$151.0K0.00%+20,626+59.3%Added
Haven Capital Group, Inc.59,143$161.0K0.15%−16,361−21.7%Reduced
KLP Kapitalforvaltning AS62,400$170.4K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.64,686$176.6K0.01%+1,258+2.0%Added
WealthTrust Axiom LLC65,000$177.4K0.05%+25,000+62.5%Added
State Board of Administration of Florida Retirement System65,451$178.7K0.00%00.0%Unchanged
Grandfield & Dodd, LLC65,930$180.0K0.01%−11,895−15.3%Reduced
Balyasny Asset Management LLC68,038$185.7K0.00%−22,586−24.9%Reduced
Headlands Technologies LLC70,662$192.9K0.02%+70,662New
Cetera Investment Advisers70,674$192.9K0.00%−5,348−7.0%Reduced
New York State Common Retirement Fund72,101$196.8K0.00%00.0%Unchanged
ProShare Advisors LLC73,733$201.3K0.00%+16,194+28.1%Added
Police & Firemen's Retirement System of New Jersey76,002$207.5K0.00%−720−0.9%Reduced
Virginia Retirement Systems Et Al82,250$224.5K0.00%−50−0.1%Reduced
Arizona State Retirement System85,490$233.4K0.00%+6,640+8.4%Added
Los Angeles Capital Management LLC119,860$233.7K0.00%+94,989+381.9%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.98,605$248.5K0.00%−25,240−20.4%Reduced
Tower Research Capital LLC (TRC)91,348$249.4K0.01%+72,357+381.0%Added
Janus Henderson Group PLC91,341$249.8K0.00%00.0%Unchanged
VARCOV Co.92,806$253.4K0.10%+92,806New
Quinn Opportunity Partners LLC95,000$259.4K0.01%−65,000−40.6%Reduced
Advisor Group Holdings, Inc.102,155$278.9K0.00%−4,249−4.0%Reduced
Citigroup Inc105,540$288.1K0.00%−304,025−74.2%Reduced
SEI Investments Co105,636$288.4K0.00%+76,976+268.6%Added
State of Wisconsin Investment Board109,997$300.3K0.00%−5,041−4.4%Reduced
Sugar Maple Asset Management, LLC110,000$300.3K0.20%+110,000New
AQR Capital Management LLC110,591$301.9K0.00%+9,193+9.1%Added
MML Investors Services, LLC111,848$305.3K0.00%+111,848New
American Century Companies Inc129,088$352.4K0.00%+100,624+353.5%Added
Portland Investment Counsel Inc.130,000$354.9K0.11%00.0%Unchanged
Intellectus Partners, LLC132,446$361.6K0.07%+1,384+1.1%Added
Intech Investment Management LLC136,763$373.4K0.00%+10,948+8.7%Added
Quantitative Investment Management, LLC138,583$378.0K0.04%+138,583New
Perceptive Advisors LLC152,714$416.9K0.01%+152,714New
Baird Financial Group, Inc.157,540$430.1K0.00%−4,035−2.5%Reduced
Creative Planning158,653$433.1K0.00%+59,425+59.9%Added
EFG International AG168,000$458.6K0.01%+168,000New
Group One Trading, L.P.168,677$460.5K0.01%−261,177−60.8%Reduced
MetLife Investment Management170,782$466.2K0.00%+29,096+20.5%Added
Tudor Investment Corp Et Al179,494$490.0K0.00%+57,750+47.4%Added
Capital Fund Management S.A.181,074$494.3K0.00%−120,004−39.9%Reduced
HSBC Holdings PLC180,541$497.4K0.00%+156,517+651.5%Added
Mirae Asset Global ETFs Holdings Ltd.183,968$503.9K0.00%+39,052+26.9%Added
Engineers Gate Manager LP194,691$531.5K0.01%+194,691New
Leonteq Securities AG195,000$532.4K0.03%+100,000+105.3%Added
Parametrica Management Ltd195,878$534.7K0.82%00.0%Unchanged
Russell Investments Group, Ltd.198,043$540.7K0.00%+131,072+195.7%Added
Scientech Research LLC211,477$577.3K0.36%+211,477New
Manufacturers Life Insurance Company, The231,443$637.3K0.00%+6,228+2.8%Added
Legal & General Group Plc258,676$706.2K0.00%+4,114+1.6%Added
Alliancebernstein L.P.258,890$706.8K0.00%00.0%Unchanged
Profund Advisors LLC260,660$711.6K0.02%+156,253+149.7%Added
ExodusPoint Capital Management, LP281,477$768.4K0.01%+239,354+568.2%Added
California State Teachers Retirement System295,997$808.1K0.00%+45,058+18.0%Added
Corsair Capital Management, L.P.300,000$819.0K0.14%+300,000New
Virtus Investment Advisers, Inc.310,641$848.0K0.23%+118,263+61.5%Added
Jain Global LLC312,096$852.0K0.01%+312,096New
Kennondale Capital Management LLC318,188$868.7K0.64%00.0%Unchanged
Quadrature Capital Ltd318,703$870.1K0.01%+318,703New
Simplex Trading, LLC329,063$898.3K0.03%+46,903+16.6%Added