| Oct 8, 2025 (view filing) | Oct 6 | 2 days | O'Neil Patrick R.EVP CLO & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.4K | $69.74 | −$937.4K | −20.0%53.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 8, 2025 (view filing) | Oct 6 | 2 days | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.85K | $69.02 | −$472.7K | −18.4%30.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 16, 2025 (view filing) | Oct 14-15 | 2 days | Birchler BrianEVP, Corp and Development Ops | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −23.9K | $72.13 | −$1.72M | −29.6%56.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 16, 2025 (view filing) | Oct 15-16 | 1 day | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.26K | $73.06 | −$530.6K | −29.3%17.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 16, 2025 (view filing) | Oct 15 | 1 day | Parshall B LynneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $71.74 | −$358.7K | −7.5%61.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 16, 2025 (view filing) | Oct 16 | Same day | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −53 | $73.62 | −$3.90K | −17.2%256 after | |
| Nov 3, 2025 (view filing) | Oct 31 | 3 days | Loscalzo JosephDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.0K | $75.10 | −$1.20M | −30.6%36.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 3, 2025 (view filing) | Oct 30-31 | 4 days | Wender Joseph HDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −28.0K | $74.02 | −$2.07M | −30.4%64.0K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 3, 2025 (view filing) | Oct 31 | 3 days | Geary Richard SEVP, Chief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −89.2K | $75.11 | −$6.70M | −59.9%59.7K after | From originalReported on the original filing 0000874015-25-000270. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's.3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 7, 2025 (view filing) | Nov 3 | 4 days | Geary Richard SEVP, Chief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.68K | $75.05 | −$126.1K | −2.7%59.7K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing.2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 7, 2025 (view filing) | Nov 5-6 | 2 days | Geary Richard SEVP, Chief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.6K | $75.69 | −$2.62M | −36.7%59.7K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 7, 2025 (view filing) | Nov 6 | 1 day | Birchler BrianEVP, Corp and Development Ops | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.00K | $76.17 | −$609.4K | −14.1%48.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 20, 2025 (view filing) | Nov 19 | 1 day | Herman Joan EDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −44.0K | $72.13 | −$3.17M | −48.8%46.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 28, 2025 (view filing) | Nov 25 | 3 days | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.8K | $80.91 | −$1.36M | −49.0%17.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 28, 2025 (view filing) | Nov 25 | 3 days | Klein Joseph IIIDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.0K | $80.00 | −$960.0K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 3, 2025 (view filing) | Dec 1 | 2 days | Wender Joseph HDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −28.0K | $80.82 | −$2.26M | −43.7%36.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 6, 2026 (view filing) | Jan 2 | 4 days | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −23.5K | $79.12 | −$1.86M | −43.5%30.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 9, 2026 (view filing) | Jan 7 | 2 days | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −44.2K | $85.08 | −$3.76M | −71.6%17.5K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.91K | $75.75 | −$523.2K | −14.6%40.4K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.15K | $75.78 | −$87.1K | −19.4%4.77K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Bennett C FrankEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.98K | $75.15 | −$674.6K | −8.7%94.8K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Birchler BrianEVP, Corp and Development Ops | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.48K | $75.11 | −$636.9K | −12.3%60.4K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.35K | $75.95 | −$634.4K | −24.0%26.5K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Hougen Elizabeth LEVP, Finance & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.9K | $75.22 | −$972.0K | −9.3%126.3K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Jenne KyleEVP, Chf GL Pdt Str Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.82K | $75.96 | −$138.5K | −10.0%16.4K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Kordasiewicz Holly B.EVP, Chief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.14K | $75.66 | −$313.3K | −22.0%14.7K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Monia Brett PChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −44.0K | $74.82 | −$3.29M | −16.4%224.7K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | O'Neil Patrick R.EVP CLO & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.19K | $75.84 | −$697.0K | −12.2%66.2K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Schneider EugeneEVP, Chf Clinical Develop Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.30K | $75.59 | −$703.1K | −12.7%63.9K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.88K | $75.34 | −$744.7K | −19.1%41.9K after | |
| Jan 20, 2026 (view filing) | Jan 16 | 4 days | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −49 | $75.97 | −$3.72K | −13.4%318 after | |
| Jan 23, 2026 (view filing) | Jan 22 | 1 day | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.98K | $81.34 | −$323.5K | −15.0%22.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.30K | $82.96 | −$439.4K | −10.4%45.4K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Bennett C FrankEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.88K | $82.95 | −$488.2K | −5.5%100.3K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Birchler BrianEVP, Corp and Development Ops | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.18K | $83.03 | −$513.0K | −8.5%66.2K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Hougen Elizabeth LEVP, Finance & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.99K | $83.24 | −$581.7K | −5.0%132.9K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Monia Brett PChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −63.0K | $82.72 | −$5.21M | −18.2%283.9K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | O'Neil Patrick R.EVP CLO & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.18K | $83.53 | −$516.1K | −7.9%72.0K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Schneider EugeneEVP, Chf Clinical Develop Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.18K | $83.45 | −$515.6K | −8.1%69.7K after | |
| Feb 2, 2026 (view filing) | Jan 30 | 3 days | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.18K | $82.93 | −$512.4K | −11.5%47.7K after | |
| Feb 4, 2026 (view filing) | Feb 2 | 2 days | Bennett C FrankEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −85.1K | $82.93 | −$7.06M | −51.4%80.3K after | From originalReported on the original filing 0000874015-26-000104. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's.3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 10, 2026 (view filing) | Feb 6 | 4 days | Monia Brett PChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.4K | $85.79 | −$2.52M | −10.4%254.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 13, 2026 (view filing) | Feb 11 | 2 days | Parshall B LynneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $82.72 | −$413.6K | −8.2%56.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 13, 2026 (view filing) | Feb 13 | Same day | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.6K | $81.76 | −$1.28M | −32.8%32.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 3 | 2 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.10K | $79.36 | −$325.1K | −9.0%41.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 3-4 | 2 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.56K | $80.35 | −$205.9K | −37.1%4.35K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 3 | 2 days | Bennett C FrankEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −85.1K | $79.23 | −$6.74M | −51.4%80.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 3 | 2 days | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.1K | $79.40 | −$1.60M | −47.1%22.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 3 | 2 days | Diaz Allene M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −54.9K | $79.35 | −$4.35M | −93.5%3.81K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 3 | 2 days | Klein Joseph IIIDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.3K | $79.51 | −$1.70M | −65.9%11.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |