Skip to main content

Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 3 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q3 2026 data is still coming in (13F filing deadline: Nov 16, 2026), so these numbers are incomplete.

Q3 2026 vs. Q2 2026

How the institutions holding Ionis Pharmaceuticals Inc changed between Q2 2026 and Q3 2026.

All holders in Q3 2026All holders in Q2 2026

13F holders of IONS: Q2 2026 compared with Q3 2026
MeasureQ2 2026Of which not filed for Q3 2026Q3 2026Change
Holders51551230
Shares179.7M179.7M2.06K+387 (+23.2%)
Value$14.3B$14.3B$91.8K−$40.6K (−30.6%)

512 institutions that held it in Q2 2026 haven't filed for Q3 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (0)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2026 but not at the end of Q2 2026.

None.

Sold out (0)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q2 2026 and filed for Q3 2026 without it.

None.

Not filed for Q3 2026 yet (512)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q2 2026 and haven't filed a 13F for Q3 2026. Not filing isn't selling, so they aren't counted as sold out.

Showing the largest 100 of 512 by value.

Institutions holding IONS in Q2 2026 that haven't filed for Q3 2026
InstitutionShares, Q2 2026Value, Q2 2026
FMR LLC24,631,956$1.95B
Capital World Investors21,669,226$1.72B
BlackRock, Inc.10,704,660$848.8M
Vanguard Portfolio Management LLC7,859,529$623.2M
Wellington Management Group LLP7,651,415$606.7M
Vanguard Capital Management LLC7,211,497$571.8M
Two Sigma Investments, LP6,252,342$495.7M
Royal Bank of Canada6,182,479$490.2M
State Street Corp4,334,848$343.7M
T. Rowe Price Investment Management, Inc.3,959,372$313.9M
Geode Capital Management, LLC3,584,024$294.8M
Price T Rowe Associates Inc3,184,500$252.5M
JPMorgan Chase & Co2,671,717$216.2M
Artisan Partners Limited Partnership2,640,024$209.3M
Tweedy, Browne Co LLC2,280,311$180.8M
Deep Track Capital, LP2,200,000$174.4M
Goldman Sachs Group Inc2,109,945$167.3M
Baker Bros. Advisors LP2,047,727$162.4M
Deerfield Management Company, L.P. (Series C)1,979,669$157.0M
American Century Companies Inc1,947,076$154.4M
Franklin Resources Inc1,623,377$128.7M
Charles Schwab Investment Management Inc1,605,054$127.3M
Barclays PLC1,603,136$127.1M
Pictet Asset Management Holding SA1,596,998$127.0M
UBS Asset Management Americas Inc1,454,672$115.3M
Polar Capital Holdings Plc1,454,021$115.3M
Alyeska Investment Group, L.P.1,417,916$112.4M
Nomura Asset Management International Inc.1,300,392$103.1M
Morgan Stanley1,281,444$101.6M
Invesco Ltd.1,120,707$88.9M
Vanguard Fiduciary Trust Co1,060,845$84.1M
Bellevue Group AG972,258$77.1M
Groupama Asset Managment937,083$75.2M
Northern Trust Corp913,610$72.4M
Capital International Investors823,764$65.3M
Davern Capital Partners, LP798,709$63.3M
Bank of America Corp790,990$62.7M
Summit Partners Public Asset Management, LLC787,263$62.4M
GW&K Investment Management, LLC746,966$59.2M
BNP PARIBAS ASSET MANAGEMENT Holding S.A.734,219$58.2M
Nuveen, LLC726,282$57.6M
Connor, Clark & Lunn Investment Management Ltd.684,236$54.3M
Eversept Partners, LP664,684$52.7M
Voloridge Investment Management, LLC655,454$52.0M
Massachusetts Financial Services Co651,816$51.7M
Neuberger Berman Group LLC633,533$50.2M
Arrowstreet Capital, Limited Partnership632,028$50.1M
UBS Group AG624,874$49.5M
TimesSquare Capital Management, LLC614,070$48.7M
Eventide Asset Management, LLC575,000$45.6M
Perceptive Advisors LLC566,000$44.9M
Renaissance Technologies LLC559,414$44.4M
Bank of New York Mellon Corp542,454$43.0M
Teacher Retirement System of Texas522,317$41.4M
Boone Capital Management LLC519,977$41.2M
Jane Street Group, LLC503,647$39.9M
New York State Common Retirement Fund500,050$39.6M
BNP Paribas Arbitrage, SA454,649$36.0M
Candriam Luxembourg S.C.A.445,019$35.3M
First Trust Advisors LP427,197$33.9M
Pinnacle Associates Ltd419,752$33.3M
Nomura Holdings Inc402,192$31.9M
Handelsbanken Fonder AB383,211$30.4M
C WorldWide Group Holding A/S366,000$29.0M
TD Asset Management Inc340,548$27.0M
Freestone Grove Partners LP339,967$27.0M
Qube Research & Technologies Ltd333,952$26.5M
Capital Research Global Investors331,936$26.3M
Capital Fund Management S.A.329,554$26.1M
Alliancebernstein L.P.340,450$25.6M
Carmignac Gestion321,000$25.5M
Privium Fund Management B.V.319,924$25.4M
Swiss National Bank315,000$25.0M
Jump Financial, LLC306,330$24.3M
ARK Investment Management LLCSuperinvestorARK Invest300,770$23.8M
Legal & General Group Plc299,184$23.7M
D. E. Shaw & Co., Inc.297,041$23.6M
Millennium Management LLC288,872$22.9M
Davenport & Co LLC283,960$22.5M
Standard Life Aberdeen plc277,400$22.0M
California Public Employees Retirement System270,843$21.5M
Tocqueville Asset Management L.P.251,215$19.9M
Raymond James Financial Inc237,348$18.8M
Citadel Advisors LLC236,284$18.7M
Universal- Beteiligungs- und Servicegesellschaft mbH233,499$18.5M
Wells Fargo & Company226,213$17.9M
Empowered Funds, LLC223,142$17.7M
Orion Investment Co220,335$17.5M
Life Cycle Investment Partners Ltd219,896$17.4M
Algert Global LLC206,853$16.4M
Stifel Financial Corp202,983$16.1M
CI Private Wealth, LLC196,661$15.6M
Eagle Health Investments LP194,577$15.4M
HSBC Holdings PLC188,402$15.0M
Sector Gamma AS189,468$15.0M
California State Teachers Retirement System180,949$14.3M
Polymer Capital Management (HK) LTD177,897$14.1M
Deutsche Bank AG169,614$13.4M
ADAR1 Capital Management, LLC166,286$13.2M
Rhumbline Advisers164,911$13.1M