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Monte Rosa Therapeutics, Inc.

GLUE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001826457

In the last 90 days, Monte Rosa Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 192 institutions reported holding it in 13F filings for Q2 2026, worth $2.24B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Monte Rosa Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
+33 vs. Q3 2025
Shares held
64.5M
+4.44M (+7.4%) vs. Q3 2025
Total value
$1.01B
+$566.1M (+127.3%) vs. Q3 2025
New holders
49
54 more added
Sold out
16
39 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GLUE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 161 institutions
Q1 2021: 0 institutionsQ2 2021: 48 institutionsQ3 2021: 56 institutionsQ4 2021: 53 institutionsQ1 2022: 52 institutionsQ2 2022: 57 institutionsQ3 2022: 70 institutionsQ4 2022: 66 institutionsQ1 2023: 69 institutionsQ2 2023: 68 institutionsQ3 2023: 71 institutionsQ4 2023: 71 institutionsQ1 2024: 68 institutionsQ2 2024: 75 institutionsQ3 2024: 81 institutionsQ4 2024: 105 institutionsQ1 2025: 106 institutionsQ2 2025: 116 institutionsQ3 2025: 129 institutionsQ4 2025: 161 institutionsQ1 2026: 191 institutionsQ2 2026: 192 institutions
Value heldQ4 2025: $1.01B
Q1 2021: $0Q2 2021: $705.1MQ3 2021: $759.4MQ4 2021: $742.0MQ1 2022: $559.9MQ2 2022: $375.0MQ3 2022: $328.8MQ4 2022: $313.8MQ1 2023: $309.8MQ2 2023: $272.3MQ3 2023: $201.4MQ4 2023: $226.6MQ1 2024: $281.3MQ2 2024: $171.7MQ3 2024: $263.7MQ4 2024: $423.3MQ1 2025: $276.2MQ2 2025: $280.6MQ3 2025: $444.9MQ4 2025: $1.01BQ1 2026: $1.43BQ2 2026: $2.24B
Institutions holding GLUE and their total value by quarter
QuarterHoldersValue
Q2 2026192$2.24B
Q1 2026191$1.43B
Q4 2025161$1.01B
Q3 2025129$444.9M
Q2 2025116$280.6M
Q1 2025106$276.2M
Q4 2024105$423.3M
Q3 202481$263.7M
Q2 202475$171.7M
Q1 202468$281.3M
Q4 202371$226.6M
Q3 202371$201.4M
Q2 202368$272.3M
Q1 202369$309.8M
Q4 202266$313.8M
Q3 202270$328.8M
Q2 202257$375.0M
Q1 202252$559.9M
Q4 202153$742.0M
Q3 202156$759.4M
Q2 202148$705.1M
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Monte Rosa Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding GLUE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
NEA Management Company, LLC7,692,298$120.6M6.15%00.0%Unchanged
Price T Rowe Associates Inc5,118,904$80.3M0.01%+481,844+10.4%Added
TCG Crossover Management, LLC4,622,151$72.5M2.40%+4,622,151New
Versant Venture Management, LLC4,382,687$68.7M45.49%−1,270,235−22.5%Reduced
Baker Bros. Advisors LP4,345,736$68.1M0.40%−570,359−11.6%Reduced
BlackRock, Inc.4,181,161$65.6M0.00%+366,028+9.6%Added
BVF Inc3,835,886$60.1M2.02%−1,824,246−32.2%Reduced
Suvretta Capital Management, LLC3,360,000$52.7M1.31%00.0%Unchanged
Vanguard Group Inc3,246,500$50.9M0.00%+257,547+8.6%Added
State Street Corp2,107,480$33.0M0.00%+1,260,707+148.9%Added
Aisling Capital Management LP1,472,331$23.1M4.82%00.0%Unchanged
American Century Companies Inc1,329,619$20.8M0.01%+736,225+124.1%Added
FMR LLC1,300,096$20.4M0.00%−1,512,155−53.8%Reduced
Geode Capital Management, LLC1,204,844$18.9M0.00%+53,278+4.6%Added
MPM Oncology Impact Management LP1,173,376$18.4M2.11%+1,173,376New
Silverarc Capital Management, LLC1,029,066$16.1M2.33%+334,124+48.1%Added
Braidwell LP948,316$14.9M0.48%+948,316New
Morgan Stanley805,530$12.6M0.00%+160,334+24.9%Added
AQR Capital Management LLC785,057$12.3M0.01%+67,795+9.5%Added
Vestal Point Capital, LP775,000$12.2M0.45%−25,000−3.1%Reduced
Alphabet Inc.744,948$11.7M0.45%−719,067−49.1%Reduced
Parkwood LLC708,000$11.1M0.94%00.0%Unchanged
Northern Trust Corp697,034$10.9M0.00%−43,650−5.9%Reduced
Dimensional Fund Advisors LP568,367$8.91M0.00%−63,815−10.1%Reduced
Bridgeway Capital Management, LLC523,377$8.21M0.17%+164,527+45.8%Added
Charles Schwab Investment Management Inc448,714$7.04M0.00%+65,446+17.1%Added
Marshall Wace, LLP398,890$6.25M0.01%−503,944−55.8%Reduced
Invesco Ltd.362,213$5.68M0.00%+264,315+270.0%Added
Arrowstreet Capital, Limited Partnership307,651$4.82M0.00%+307,651New
Goldman Sachs Group Inc295,878$4.64M0.00%+194,734+192.5%Added
Nuveen, LLC285,859$4.48M0.00%+182,891+177.6%Added
Nextech Invest, Ltd.279,237$4.38M0.42%+279,237New
Empowered Funds, LLC278,077$4.36M0.07%+190,627+218.0%Added
Acadian Asset Management LLC247,855$3.88M0.01%+44,305+21.8%Added
Bank of America Corp223,571$3.51M0.00%−46,072−17.1%Reduced
ADAR1 Capital Management, LLC215,752$3.38M0.25%00.0%Unchanged
TD Asset Management Inc213,464$3.35M0.00%+41,386+24.1%Added
Nomura Asset Management International Inc.200,000$3.14M0.00%+200,000New
Bank of New York Mellon Corp173,304$2.72M0.00%−13,494−7.2%Reduced
Trexquant Investment LP149,712$2.35M0.02%+149,712New
Wellington Management Group LLP148,057$2.32M0.00%−10,467−6.6%Reduced
Atom Investors LP137,261$2.15M0.17%+137,261New
Jane Street Group, LLC137,049$2.15M0.00%−170,000−55.4%Reduced
Manufacturers Life Insurance Company, The134,674$2.15M0.00%+16,291+13.8%Added
Barclays PLC135,984$2.13M0.00%+63,029+86.4%Added
UBS Group AG123,000$1.93M0.00%+50,905+70.6%Added
Ameriprise Financial Inc122,164$1.92M0.00%+122,164New
Millennium Management LLC103,972$1.63M0.00%−340,967−76.6%Reduced
Campbell & CO Investment Adviser LLC90,752$1.42M0.07%+39,619+77.5%Added
Ieq Capital, LLC89,268$1.40M0.00%+30,202+51.1%Added
Casdin Capital, LLC86,014$1.35M0.08%00.0%Unchanged
D. E. Shaw & Co., Inc.85,488$1.34M0.00%+35,275+70.3%Added
Franklin Resources Inc85,231$1.34M0.00%+41,811+96.3%Added
EAM Investors, LLC70,037$1.10M0.12%+70,037New
Canada Pension Plan Investment Board68,100$1.07M0.00%+68,100New
Rangeley Capital, LLC67,500$1.06M0.91%−45,500−40.3%Reduced
Rafferty Asset Management, LLC67,438$1.06M0.00%+67,438New
Alliancebernstein L.P.63,480$995.4K0.00%00.0%Unchanged
Advisory Research Inc63,220$991.3K0.12%+63,220New
Diadema Partners LP62,281$976.6K0.58%+62,281New
Rhumbline Advisers61,859$969.9K0.00%−2,087−3.3%Reduced
StemPoint Capital LP61,577$965.5K0.17%+61,577New
SEI Investments Co59,668$935.6K0.00%+43,262+263.7%Added
Nantahala Capital Management, LLC57,991$909.3K0.05%+57,991New
Wells Fargo & Company52,588$824.6K0.00%+16,308+45.0%Added
Massachusetts Financial Services Co49,630$778.2K0.00%+49,630New
Citadel Advisors LLC46,263$725.4K0.00%−4,746−9.3%Reduced
STRS Ohio36,100$566.0K0.00%+36,100New
Voloridge Investment Management, LLC35,783$561.1K0.00%+35,783New
Simplex Trading, LLC35,124$550.7K0.02%+2,011+6.1%Added
Quantinno Capital Management LP33,580$526.5K0.00%+3,466+11.5%Added
Deutsche Bank AG33,108$519.1K0.00%+8,537+34.7%Added
J. Goldman & Co LP32,291$506.3K0.02%+32,291New
XTX Topco Ltd31,125$488.0K0.01%−19,003−37.9%Reduced
Aquatic Capital Management LLC30,940$485.1K0.01%+30,940New
CWM, LLC29,444$462.0K0.00%+3,536+13.6%Added
Quest Partners LLC28,322$444.1K0.02%+1,071+3.9%Added
Allspring Global Investments Holdings, LLC26,955$422.7K0.00%+2,358+9.6%Added
Voya Investment Management LLC26,382$413.7K0.00%+26,382New
MetLife Investment Management26,187$410.6K0.00%+1,831+7.5%Added
Mirae Asset Global ETFs Holdings Ltd.25,552$401.8K0.00%+4,287+20.2%Added
Profund Advisors LLC25,219$395.4K0.01%+25,219New
NEOS Investment Management LLC25,137$394.1K0.00%+25,137New
Tema ETFs LLC24,767$388.3K0.03%+24,767New
JPMorgan Chase & Co24,120$378.2K0.00%+1,181+5.1%Added
Creative Planning23,403$367.0K0.00%+23,403New
Winton Group Ltd22,930$359.5K0.01%+22,930New
Wealth Enhancement Advisory Services, LLC22,289$356.8K0.00%+3,746+20.2%Added
Los Angeles Capital Management LLC26,806$348.7K0.00%−1,599−5.6%Reduced
Persistent Asset Partners Ltd22,211$348.3K0.17%+22,211New
Mariner, LLC21,600$339.7K0.00%+7,837+56.9%Added
State of Wisconsin Investment Board19,628$307.8K0.00%−207−1.0%Reduced
Brookwood Investment Group LLC19,535$306.3K0.04%+19,535New
Intech Investment Management LLC19,392$304.1K0.00%+5,987+44.7%Added
Virtu Financial LLC18,717$293.0K0.01%+6,765+56.6%Added
China Universal Asset Management Co., Ltd.18,611$291.8K0.02%−12,214−39.6%Reduced
SG Americas Securities, LLC17,279$271.0K0.00%+17,279New
Man Group plc16,312$255.8K0.00%−24,263−59.8%Reduced
Virtus Investment Advisers, Inc.16,310$255.7K0.07%−6,818−29.5%Reduced
State Board of Administration of Florida Retirement System14,950$234.4K0.00%00.0%Unchanged