Monte Rosa Therapeutics, Inc.
GLUE- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001826457
In the last 90 days, Monte Rosa Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 192 institutions reported holding it in 13F filings for Q2 2026, worth $2.24B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Monte Rosa Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 161
- +33 vs. Q3 2025
- Shares held
- 64.5M
- +4.44M (+7.4%) vs. Q3 2025
- Total value
- $1.01B
- +$566.1M (+127.3%) vs. Q3 2025
- New holders
- 49
- 54 more added
- Sold out
- 16
- 39 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GLUE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 192 | $2.24B |
| Q1 2026 | 191 | $1.43B |
| Q4 2025 | 161 | $1.01B |
| Q3 2025 | 129 | $444.9M |
| Q2 2025 | 116 | $280.6M |
| Q1 2025 | 106 | $276.2M |
| Q4 2024 | 105 | $423.3M |
| Q3 2024 | 81 | $263.7M |
| Q2 2024 | 75 | $171.7M |
| Q1 2024 | 68 | $281.3M |
| Q4 2023 | 71 | $226.6M |
| Q3 2023 | 71 | $201.4M |
| Q2 2023 | 68 | $272.3M |
| Q1 2023 | 69 | $309.8M |
| Q4 2022 | 66 | $313.8M |
| Q3 2022 | 70 | $328.8M |
| Q2 2022 | 57 | $375.0M |
| Q1 2022 | 52 | $559.9M |
| Q4 2021 | 53 | $742.0M |
| Q3 2021 | 56 | $759.4M |
| Q2 2021 | 48 | $705.1M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Monte Rosa Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Two Sigma Investments, LP | 14,000 | $219.5K | 0.00% | −147,481−91.3% | Reduced |
| Colony Group, LLC | 13,776 | $216.0K | 0.00% | +2,052+17.5% | Added |
| Axq Capital, LP | 13,742 | $215.5K | 0.05% | +13,742 | New |
| Brevan Howard Capital Management LP | 13,323 | $208.9K | 0.00% | −33,589−71.6% | Reduced |
| Essential Partners LLC | 13,128 | $205.8K | 0.06% | +106+0.8% | Added |
| Gsa Capital Partners LLP | 12,981 | $204.0K | 0.02% | −120,474−90.3% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 12,417 | $194.7K | 0.00% | −3,580−22.4% | Reduced |
| Martingale Asset Management L P | 12,413 | $194.6K | 0.00% | +12,413 | New |
| New York State Common Retirement Fund | 12,174 | $190.9K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 11,374 | $178.3K | 0.00% | +1,199+11.8% | Added |
| Pallas Capital Advisors LLC | 11,320 | $177.5K | 0.01% | +126+1.1% | Added |
| Baader Bank INC | 11,000 | $172.5K | 0.01% | +11,000 | New |
| Mercer Global Advisors Inc | 10,971 | $172.0K | 0.00% | +10,971 | New |
| Susquehanna International Group, LLP | 10,907 | $171.0K | 0.00% | −5,279−32.6% | Reduced |
| Citigroup Inc | 10,686 | $167.6K | 0.00% | +8,912+502.4% | Added |
| Wealth Effects LLC | 10,099 | $158.4K | 0.05% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 10,029 | $157.3K | 0.00% | −84,678−89.4% | Reduced |
| Mayflower Financial Advisors, LLC | 10,000 | $156.8K | 0.02% | +10,000 | New |
| Sterling Capital Management LLC | 9,508 | $149.1K | 0.00% | +6,290+195.5% | Added |
| BNP Paribas Arbitrage, SA | 5,694 | $89.3K | 0.00% | −4,039−41.5% | Reduced |
| Russell Investments Group, Ltd. | 4,318 | $67.7K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 4,245 | $66.6K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 4,184 | $65.6K | 0.00% | 00.0% | Unchanged |
| Seven Fleet Capital Management LP | 4,000 | $62.7K | 0.04% | +4,000 | New |
| Advisor Group Holdings, Inc. | 3,418 | $53.6K | 0.00% | +933+37.5% | Added |
| EverSource Wealth Advisors, LLC | 3,281 | $51.4K | 0.00% | +294+9.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,164 | $49.6K | 0.00% | +776+32.5% | Added |
| Nisa Investment Advisors, LLC | 3,151 | $49.4K | 0.00% | +451+16.7% | Added |
| California State Teachers Retirement System | 2,872 | $45.0K | 0.00% | −179−5.9% | Reduced |
| Royal Bank of Canada | 2,818 | $44.0K | 0.00% | −432,949−99.4% | Reduced |
| GAMMA Investing LLC | 1,905 | $29.9K | 0.00% | +1,905 | New |
| Amalgamated Bank | 1,465 | $23.0K | 0.00% | +40+2.8% | Added |
| Federated Hermes, Inc. | 1,323 | $20.7K | 0.00% | +1,323 | New |
| GF Fund Management Co. Ltd. | 1,279 | $20.1K | 0.00% | −38−2.9% | Reduced |
| Allworth Financial LP | 1,247 | $19.6K | 0.00% | +649+108.5% | Added |
| IFP Advisors, Inc | 1,218 | $19.1K | 0.00% | +66+5.7% | Added |
| Rockefeller Capital Management L.P. | 1,061 | $16.6K | 0.00% | +1,061 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,054 | $16.5K | 0.00% | 00.0% | Unchanged |
| Paladin Partners, LLC | 1,000 | $15.7K | 0.01% | +1,000 | New |
| Tower Research Capital LLC (TRC) | 686 | $10.8K | 0.00% | −2,757−80.1% | Reduced |
| Comerica Bank | 596 | $9.35K | 0.00% | −245−29.1% | Reduced |
| UBS Asset Management Americas Inc | 570 | $8.94K | 0.00% | +570 | New |
| Spire Wealth Management | 509 | $7.98K | 0.00% | +509 | New |
| SRS Capital Advisors, Inc. | 460 | $7.21K | 0.00% | −31,985−98.6% | Reduced |
| The PNC Financial Services Group, Inc. | 457 | $7.17K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 439 | $6.88K | 0.00% | +439 | New |
| Covestor Ltd | 387 | $6.00K | 0.00% | +387 | New |
| Optiver Holding B.V. | 266 | $4.17K | 0.00% | −318−54.5% | Reduced |
| SBI Securities Co., Ltd. | 238 | $3.73K | 0.00% | −80−25.2% | Reduced |
| Daiwa Securities Group Inc. | 203 | $3.00K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 181 | $2.84K | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 111 | $1.74K | 0.00% | +27+32.1% | Added |
| Rothschild Investment LLC | 100 | $1.57K | 0.00% | +50+100.0% | Added |
| Bessemer Group Inc | 34 | $1.00K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 37 | $591 | 0.00% | +37 | New |
| MAI Capital Management | 33 | $518 | 0.00% | +33 | New |
| SJS Investment Consulting Inc. | 29 | $455 | 0.00% | +29 | New |
| Caitong International Asset Management Co., Ltd | 27 | $423 | 0.00% | +27 | New |
| Turning Point Benefit Group, Inc. | 14 | $219 | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 8 | $126 | 0.00% | −27−77.1% | Reduced |
| Sunbelt Securities, Inc. | 1 | $16 | 0.00% | +1 | New |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −408,540−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −395,733−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| JBF Capital, Inc. | 0 | $0 | 0.00% | −148,566−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −147,726−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −90,419−100.0% | Sold out |
| Mackenzie Financial Corp | 0 | $0 | 0.00% | −77,635−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −28,300−100.0% | Sold out |
| Bailard, Inc. | 0 | $0 | 0.00% | −22,500−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −16,254−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −12,054−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −11,100−100.0% | Sold out |
| Royce & Associates LP | 0 | $0 | 0.00% | −11,024−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −10,871−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −10,202−100.0% | Sold out |
| Summit Wealth Group LLC | 0 | $0 | 0.00% | −2,002−100.0% | Sold out |
| Point72 Europe (London) LLP | – | – | – | – | Not filed |