Monte Rosa Therapeutics, Inc.
GLUE- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001826457
In the last 90 days, Monte Rosa Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 192 institutions reported holding it in 13F filings for Q2 2026, worth $2.24B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Monte Rosa Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 161
- +33 vs. Q3 2025
- Shares held
- 64.5M
- +4.44M (+7.4%) vs. Q3 2025
- Total value
- $1.01B
- +$566.1M (+127.3%) vs. Q3 2025
- New holders
- 49
- 54 more added
- Sold out
- 16
- 39 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GLUE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 192 | $2.24B |
| Q1 2026 | 191 | $1.43B |
| Q4 2025 | 161 | $1.01B |
| Q3 2025 | 129 | $444.9M |
| Q2 2025 | 116 | $280.6M |
| Q1 2025 | 106 | $276.2M |
| Q4 2024 | 105 | $423.3M |
| Q3 2024 | 81 | $263.7M |
| Q2 2024 | 75 | $171.7M |
| Q1 2024 | 68 | $281.3M |
| Q4 2023 | 71 | $226.6M |
| Q3 2023 | 71 | $201.4M |
| Q2 2023 | 68 | $272.3M |
| Q1 2023 | 69 | $309.8M |
| Q4 2022 | 66 | $313.8M |
| Q3 2022 | 70 | $328.8M |
| Q2 2022 | 57 | $375.0M |
| Q1 2022 | 52 | $559.9M |
| Q4 2021 | 53 | $742.0M |
| Q3 2021 | 56 | $759.4M |
| Q2 2021 | 48 | $705.1M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Monte Rosa Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sunbelt Securities, Inc. | 1 | $16 | 0.00% | +1 | New |
| Clearstead Advisors, LLC | 8 | $126 | 0.00% | −27−77.1% | Reduced |
| Turning Point Benefit Group, Inc. | 14 | $219 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 27 | $423 | 0.00% | +27 | New |
| SJS Investment Consulting Inc. | 29 | $455 | 0.00% | +29 | New |
| MAI Capital Management | 33 | $518 | 0.00% | +33 | New |
| Smartleaf Asset Management LLC | 37 | $591 | 0.00% | +37 | New |
| Bessemer Group Inc | 34 | $1.00K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 100 | $1.57K | 0.00% | +50+100.0% | Added |
| True Wealth Design, LLC | 111 | $1.74K | 0.00% | +27+32.1% | Added |
| Larson Financial Group LLC | 181 | $2.84K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 203 | $3.00K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 238 | $3.73K | 0.00% | −80−25.2% | Reduced |
| Optiver Holding B.V. | 266 | $4.17K | 0.00% | −318−54.5% | Reduced |
| Covestor Ltd | 387 | $6.00K | 0.00% | +387 | New |
| Farther Finance Advisors, LLC | 439 | $6.88K | 0.00% | +439 | New |
| The PNC Financial Services Group, Inc. | 457 | $7.17K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 460 | $7.21K | 0.00% | −31,985−98.6% | Reduced |
| Spire Wealth Management | 509 | $7.98K | 0.00% | +509 | New |
| UBS Asset Management Americas Inc | 570 | $8.94K | 0.00% | +570 | New |
| Comerica Bank | 596 | $9.35K | 0.00% | −245−29.1% | Reduced |
| Tower Research Capital LLC (TRC) | 686 | $10.8K | 0.00% | −2,757−80.1% | Reduced |
| Paladin Partners, LLC | 1,000 | $15.7K | 0.01% | +1,000 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,054 | $16.5K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 1,061 | $16.6K | 0.00% | +1,061 | New |
| IFP Advisors, Inc | 1,218 | $19.1K | 0.00% | +66+5.7% | Added |
| Allworth Financial LP | 1,247 | $19.6K | 0.00% | +649+108.5% | Added |
| GF Fund Management Co. Ltd. | 1,279 | $20.1K | 0.00% | −38−2.9% | Reduced |
| Federated Hermes, Inc. | 1,323 | $20.7K | 0.00% | +1,323 | New |
| Amalgamated Bank | 1,465 | $23.0K | 0.00% | +40+2.8% | Added |
| GAMMA Investing LLC | 1,905 | $29.9K | 0.00% | +1,905 | New |
| Royal Bank of Canada | 2,818 | $44.0K | 0.00% | −432,949−99.4% | Reduced |
| California State Teachers Retirement System | 2,872 | $45.0K | 0.00% | −179−5.9% | Reduced |
| Nisa Investment Advisors, LLC | 3,151 | $49.4K | 0.00% | +451+16.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,164 | $49.6K | 0.00% | +776+32.5% | Added |
| EverSource Wealth Advisors, LLC | 3,281 | $51.4K | 0.00% | +294+9.8% | Added |
| Advisor Group Holdings, Inc. | 3,418 | $53.6K | 0.00% | +933+37.5% | Added |
| Seven Fleet Capital Management LP | 4,000 | $62.7K | 0.04% | +4,000 | New |
| Ameritas Investment Partners, Inc. | 4,184 | $65.6K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 4,245 | $66.6K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 4,318 | $67.7K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 5,694 | $89.3K | 0.00% | −4,039−41.5% | Reduced |
| Sterling Capital Management LLC | 9,508 | $149.1K | 0.00% | +6,290+195.5% | Added |
| Mayflower Financial Advisors, LLC | 10,000 | $156.8K | 0.02% | +10,000 | New |
| Squarepoint Ops LLC | 10,029 | $157.3K | 0.00% | −84,678−89.4% | Reduced |
| Wealth Effects LLC | 10,099 | $158.4K | 0.05% | 00.0% | Unchanged |
| Citigroup Inc | 10,686 | $167.6K | 0.00% | +8,912+502.4% | Added |
| Susquehanna International Group, LLP | 10,907 | $171.0K | 0.00% | −5,279−32.6% | Reduced |
| Mercer Global Advisors Inc | 10,971 | $172.0K | 0.00% | +10,971 | New |
| Baader Bank INC | 11,000 | $172.5K | 0.01% | +11,000 | New |
| Pallas Capital Advisors LLC | 11,320 | $177.5K | 0.01% | +126+1.1% | Added |
| ProShare Advisors LLC | 11,374 | $178.3K | 0.00% | +1,199+11.8% | Added |
| New York State Common Retirement Fund | 12,174 | $190.9K | 0.00% | 00.0% | Unchanged |
| Martingale Asset Management L P | 12,413 | $194.6K | 0.00% | +12,413 | New |
| Police & Firemen's Retirement System of New Jersey | 12,417 | $194.7K | 0.00% | −3,580−22.4% | Reduced |
| Gsa Capital Partners LLP | 12,981 | $204.0K | 0.02% | −120,474−90.3% | Reduced |
| Essential Partners LLC | 13,128 | $205.8K | 0.06% | +106+0.8% | Added |
| Brevan Howard Capital Management LP | 13,323 | $208.9K | 0.00% | −33,589−71.6% | Reduced |
| Axq Capital, LP | 13,742 | $215.5K | 0.05% | +13,742 | New |
| Colony Group, LLC | 13,776 | $216.0K | 0.00% | +2,052+17.5% | Added |
| Two Sigma Investments, LP | 14,000 | $219.5K | 0.00% | −147,481−91.3% | Reduced |
| State Board of Administration of Florida Retirement System | 14,950 | $234.4K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 16,310 | $255.7K | 0.07% | −6,818−29.5% | Reduced |
| Man Group plc | 16,312 | $255.8K | 0.00% | −24,263−59.8% | Reduced |
| SG Americas Securities, LLC | 17,279 | $271.0K | 0.00% | +17,279 | New |
| China Universal Asset Management Co., Ltd. | 18,611 | $291.8K | 0.02% | −12,214−39.6% | Reduced |
| Virtu Financial LLC | 18,717 | $293.0K | 0.01% | +6,765+56.6% | Added |
| Intech Investment Management LLC | 19,392 | $304.1K | 0.00% | +5,987+44.7% | Added |
| Brookwood Investment Group LLC | 19,535 | $306.3K | 0.04% | +19,535 | New |
| State of Wisconsin Investment Board | 19,628 | $307.8K | 0.00% | −207−1.0% | Reduced |
| Mariner, LLC | 21,600 | $339.7K | 0.00% | +7,837+56.9% | Added |
| Persistent Asset Partners Ltd | 22,211 | $348.3K | 0.17% | +22,211 | New |
| Los Angeles Capital Management LLC | 26,806 | $348.7K | 0.00% | −1,599−5.6% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 22,289 | $356.8K | 0.00% | +3,746+20.2% | Added |
| Winton Group Ltd | 22,930 | $359.5K | 0.01% | +22,930 | New |
| Creative Planning | 23,403 | $367.0K | 0.00% | +23,403 | New |
| JPMorgan Chase & Co | 24,120 | $378.2K | 0.00% | +1,181+5.1% | Added |
| Tema ETFs LLC | 24,767 | $388.3K | 0.03% | +24,767 | New |
| NEOS Investment Management LLC | 25,137 | $394.1K | 0.00% | +25,137 | New |
| Profund Advisors LLC | 25,219 | $395.4K | 0.01% | +25,219 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 25,552 | $401.8K | 0.00% | +4,287+20.2% | Added |
| MetLife Investment Management | 26,187 | $410.6K | 0.00% | +1,831+7.5% | Added |
| Voya Investment Management LLC | 26,382 | $413.7K | 0.00% | +26,382 | New |
| Allspring Global Investments Holdings, LLC | 26,955 | $422.7K | 0.00% | +2,358+9.6% | Added |
| Quest Partners LLC | 28,322 | $444.1K | 0.02% | +1,071+3.9% | Added |
| CWM, LLC | 29,444 | $462.0K | 0.00% | +3,536+13.6% | Added |
| Aquatic Capital Management LLC | 30,940 | $485.1K | 0.01% | +30,940 | New |
| XTX Topco Ltd | 31,125 | $488.0K | 0.01% | −19,003−37.9% | Reduced |
| J. Goldman & Co LP | 32,291 | $506.3K | 0.02% | +32,291 | New |
| Deutsche Bank AG | 33,108 | $519.1K | 0.00% | +8,537+34.7% | Added |
| Quantinno Capital Management LP | 33,580 | $526.5K | 0.00% | +3,466+11.5% | Added |
| Simplex Trading, LLC | 35,124 | $550.7K | 0.02% | +2,011+6.1% | Added |
| Voloridge Investment Management, LLC | 35,783 | $561.1K | 0.00% | +35,783 | New |
| STRS Ohio | 36,100 | $566.0K | 0.00% | +36,100 | New |
| Citadel Advisors LLC | 46,263 | $725.4K | 0.00% | −4,746−9.3% | Reduced |
| Massachusetts Financial Services Co | 49,630 | $778.2K | 0.00% | +49,630 | New |
| Wells Fargo & Company | 52,588 | $824.6K | 0.00% | +16,308+45.0% | Added |
| Nantahala Capital Management, LLC | 57,991 | $909.3K | 0.05% | +57,991 | New |
| SEI Investments Co | 59,668 | $935.6K | 0.00% | +43,262+263.7% | Added |
| StemPoint Capital LP | 61,577 | $965.5K | 0.17% | +61,577 | New |