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Eton Pharmaceuticals, Inc.

ETON
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710340

In the last 90 days, Eton Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 5 sales; 164 institutions reported holding it in 13F filings for Q2 2026, worth $722.6M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Eton Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
104
+2 vs. Q3 2025
Shares held
16.4M
−1.77M (−9.7%) vs. Q3 2025
Total value
$277.5M
−$116.9M (−29.6%) vs. Q3 2025
New holders
21
28 more added
Sold out
19
37 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETON on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 104 institutions
Q1 2021: 50 institutionsQ2 2021: 46 institutionsQ3 2021: 37 institutionsQ4 2021: 32 institutionsQ1 2022: 31 institutionsQ2 2022: 29 institutionsQ3 2022: 32 institutionsQ4 2022: 31 institutionsQ1 2023: 35 institutionsQ2 2023: 33 institutionsQ3 2023: 50 institutionsQ4 2023: 56 institutionsQ1 2024: 44 institutionsQ2 2024: 45 institutionsQ3 2024: 48 institutionsQ4 2024: 71 institutionsQ1 2025: 86 institutionsQ2 2025: 87 institutionsQ3 2025: 103 institutionsQ4 2025: 104 institutionsQ1 2026: 116 institutionsQ2 2026: 164 institutions
Value heldQ4 2025: $277.5M
Q1 2021: $63.7MQ2 2021: $48.1MQ3 2021: $29.5MQ4 2021: $24.1MQ1 2022: $27.4MQ2 2022: $14.6MQ3 2022: $14.4MQ4 2022: $18.2MQ1 2023: $22.5MQ2 2023: $20.9MQ3 2023: $28.8MQ4 2023: $33.5MQ1 2024: $28.8MQ2 2024: $28.7MQ3 2024: $60.0MQ4 2024: $181.5MQ1 2025: $189.7MQ2 2025: $243.3MQ3 2025: $394.7MQ4 2025: $277.5MQ1 2026: $438.6MQ2 2026: $722.6M
Institutions holding ETON and their total value by quarter
QuarterHoldersValue
Q2 2026164$722.6M
Q1 2026116$438.6M
Q4 2025104$277.5M
Q3 2025103$394.7M
Q2 202587$243.3M
Q1 202586$189.7M
Q4 202471$181.5M
Q3 202448$60.0M
Q2 202445$28.7M
Q1 202444$28.8M
Q4 202356$33.5M
Q3 202350$28.8M
Q2 202333$20.9M
Q1 202335$22.5M
Q4 202231$18.2M
Q3 202232$14.4M
Q2 202229$14.6M
Q1 202231$27.4M
Q4 202132$24.1M
Q3 202137$29.5M
Q2 202146$48.1M
Q1 202150$63.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Eton Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ETON in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc1,348,668$22.8M0.00%+4,553+0.3%Added
BlackRock, Inc.1,738,907$29.4M0.00%+34,546+2.0%Added
EcoR1 Capital, LLC2,030,544$34.3M1.57%00.0%Unchanged
Opaleye Management Inc.2,860,000$48.4M6.38%00.0%Unchanged
Divisadero Street Capital Management, LP0$00.00%−298,000−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−200,000−100.0%Sold out
Apis Capital Advisors, LLC0$00.00%−117,600−100.0%Sold out
EAM Investors, LLC0$00.00%−52,897−100.0%Sold out
Winton Group Ltd0$00.00%−35,304−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−30,056−100.0%Sold out
Acadian Asset Management LLC0$00.00%−26,410−100.0%Sold out
Calamos Advisors LLC0$00.00%−23,634−100.0%Sold out
Hillsdale Investment Management Inc.0$00.00%−18,503−100.0%Sold out
Navellier & Associates Inc0$00.00%−17,494−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−14,785−100.0%Sold out
PharVision Advisers, LLC0$00.00%−10,535−100.0%Sold out
Alliancebernstein L.P.0$00.00%−9,600−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−9,365−100.0%Sold out
Quarry LP0$00.00%−1,700−100.0%Sold out
Comerica Bank0$00.00%−219−100.0%Sold out
Advisory Services Network, LLC0$00.00%−50−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−6−100.0%Sold out
Summit Wealth Group LLC0$00.00%−25,999−100.0%Sold out
Sheets Smith Investment Management––––Not filed