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Eton Pharmaceuticals, Inc.

ETON
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710340

In the last 90 days, Eton Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 5 sales; 164 institutions reported holding it in 13F filings for Q2 2026, worth $722.6M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Eton Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
104
+2 vs. Q3 2025
Shares held
16.4M
−1.77M (−9.7%) vs. Q3 2025
Total value
$277.5M
−$116.9M (−29.6%) vs. Q3 2025
New holders
21
28 more added
Sold out
19
37 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETON on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 104 institutions
Q1 2021: 50 institutionsQ2 2021: 46 institutionsQ3 2021: 37 institutionsQ4 2021: 32 institutionsQ1 2022: 31 institutionsQ2 2022: 29 institutionsQ3 2022: 32 institutionsQ4 2022: 31 institutionsQ1 2023: 35 institutionsQ2 2023: 33 institutionsQ3 2023: 50 institutionsQ4 2023: 56 institutionsQ1 2024: 44 institutionsQ2 2024: 45 institutionsQ3 2024: 48 institutionsQ4 2024: 71 institutionsQ1 2025: 86 institutionsQ2 2025: 87 institutionsQ3 2025: 103 institutionsQ4 2025: 104 institutionsQ1 2026: 116 institutionsQ2 2026: 164 institutions
Value heldQ4 2025: $277.5M
Q1 2021: $63.7MQ2 2021: $48.1MQ3 2021: $29.5MQ4 2021: $24.1MQ1 2022: $27.4MQ2 2022: $14.6MQ3 2022: $14.4MQ4 2022: $18.2MQ1 2023: $22.5MQ2 2023: $20.9MQ3 2023: $28.8MQ4 2023: $33.5MQ1 2024: $28.8MQ2 2024: $28.7MQ3 2024: $60.0MQ4 2024: $181.5MQ1 2025: $189.7MQ2 2025: $243.3MQ3 2025: $394.7MQ4 2025: $277.5MQ1 2026: $438.6MQ2 2026: $722.6M
Institutions holding ETON and their total value by quarter
QuarterHoldersValue
Q2 2026164$722.6M
Q1 2026116$438.6M
Q4 2025104$277.5M
Q3 2025103$394.7M
Q2 202587$243.3M
Q1 202586$189.7M
Q4 202471$181.5M
Q3 202448$60.0M
Q2 202445$28.7M
Q1 202444$28.8M
Q4 202356$33.5M
Q3 202350$28.8M
Q2 202333$20.9M
Q1 202335$22.5M
Q4 202231$18.2M
Q3 202232$14.4M
Q2 202229$14.6M
Q1 202231$27.4M
Q4 202132$24.1M
Q3 202137$29.5M
Q2 202146$48.1M
Q1 202150$63.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Eton Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ETON in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Opaleye Management Inc.2,860,000$48.4M6.38%00.0%Unchanged
EcoR1 Capital, LLC2,030,544$34.3M1.57%00.0%Unchanged
BlackRock, Inc.1,738,907$29.4M0.00%+34,546+2.0%Added
Vanguard Group Inc1,348,668$22.8M0.00%+4,553+0.3%Added
Nantahala Capital Management, LLC1,175,951$19.9M1.19%00.0%Unchanged
Geode Capital Management, LLC565,051$9.56M0.00%−8,979−1.6%Reduced
State Street Corp501,925$8.49M0.00%+63,480+14.5%Added
Morgan Stanley493,914$8.35M0.00%−92,132−15.7%Reduced
National Philanthropic Trust492,112$8.32M0.08%00.0%Unchanged
Westside Investment Management, Inc.470,940$7.96M1.27%−1,600−0.3%Reduced
Oberweis Asset Management Inc431,300$7.29M0.27%+238,940+124.2%Added
Thompson Siegel & Walmsley LLC408,541$6.91M0.12%−10,025−2.4%Reduced
BNP Paribas Arbitrage, SA277,458$4.69M0.00%+47,668+20.7%Added
Northern Trust Corp231,849$3.92M0.00%−13,202−5.4%Reduced
Cannell Capital LLC216,917$3.67M2.34%−238,488−52.4%Reduced
Renaissance Technologies LLC205,700$3.48M0.01%−118,921−36.6%Reduced
Goldman Sachs Group Inc196,263$3.32M0.00%+6,099+3.2%Added
Diametric Capital, LP193,155$3.27M0.88%+93,846+94.5%Added
JPMorgan Chase & Co185,439$3.14M0.00%−165,978−47.2%Reduced
Lumbard & Kellner, LLC174,944$2.96M1.04%−1,356−0.8%Reduced
Aristides Capital LLC161,436$2.73M0.94%−6,151−3.7%Reduced
Bank of New York Mellon Corp127,700$2.16M0.00%−1,482−1.1%Reduced
UBS Group AG126,674$2.14M0.00%−93,687−42.5%Reduced
Jefferies Financial Group Inc.118,300$2.00M0.02%+29,860+33.8%Added
Bank of America Corp104,796$1.77M0.00%+30,139+40.4%Added
Woodline Partners LP95,487$1.61M0.01%+95,487New
Bridgeway Capital Management, LLC84,020$1.42M0.03%−25,000−22.9%Reduced
Wellington Management Group LLP81,201$1.37M0.00%−7,018−8.0%Reduced
Millennium Management LLC79,331$1.34M0.00%+63,469+400.1%Added
Charles Schwab Investment Management Inc77,212$1.31M0.00%−62−0.1%Reduced
Two Sigma Investments, LP76,602$1.30M0.00%−209,819−73.3%Reduced
Connor, Clark & Lunn Investment Management Ltd.76,586$1.30M0.00%−67,225−46.7%Reduced
Citadel Advisors LLC74,144$1.25M0.00%+74,144New
Nuveen, LLC58,917$996.3K0.00%00.0%Unchanged
Jane Street Group, LLC58,056$981.7K0.00%−12,888−18.2%Reduced
Barclays PLC51,448$870.0K0.00%+14,642+39.8%Added
Russell Investments Group, Ltd.49,694$840.3K0.00%−5,171−9.4%Reduced
Prelude Capital Management, LLC45,325$766.4K0.06%+3,452+8.2%Added
Anchor Capital Advisors LLC40,668$687.7K0.02%+3,890+10.6%Added
XTX Topco Ltd32,527$550.0K0.01%+8,128+33.3%Added
Blair William & Co32,400$547.9K0.00%00.0%Unchanged
Rhumbline Advisers30,436$514.7K0.00%−5,688−15.7%Reduced
Wells Fargo & Company28,293$478.4K0.00%+11,584+69.3%Added
State of Wisconsin Investment Board24,615$416.2K0.00%+24,615New
Guilbault Capital LLC23,225$392.7K0.44%+23,225New
Aquatic Capital Management LLC22,802$385.6K0.01%−13,530−37.2%Reduced
Essex Investment Management Co LLC20,182$341.3K0.05%00.0%Unchanged
Invesco Ltd.19,691$333.0K0.00%+6,213+46.1%Added
Juncture Wealth Strategies, LLC18,996$321.2K0.11%+2,028+12.0%Added
Bridge City Capital, LLC18,600$314.5K0.09%+1,927+11.6%Added
Deutsche Bank AG18,249$308.6K0.00%+850+4.9%Added
Chicago Trust Co NA16,700$282.4K0.04%00.0%Unchanged
Los Angeles Capital Management LLC14,631$267.0K0.00%+14,631New
Voleon Capital Management LP15,582$263.5K0.01%+4,632+42.3%Added
MetLife Investment Management15,537$262.7K0.00%00.0%Unchanged
Price T Rowe Associates Inc15,369$260.0K0.00%+1,845+13.6%Added
D. E. Shaw & Co., Inc.15,331$259.2K0.00%+15,331New
PDT Partners, LLC14,891$251.8K0.02%00.0%Unchanged
Two Sigma Advisers, LP14,700$248.6K0.00%−154,200−91.3%Reduced
Squarepoint Ops LLC13,482$228.0K0.00%−46,163−77.4%Reduced
Point72 Asset Management, L.P.12,925$218.6K0.00%+12,925New
Canada Pension Plan Investment Board12,500$211.4K0.00%+12,500New
Intech Investment Management LLC12,421$210.0K0.00%+1,244+11.1%Added
Raymond James Financial Inc12,250$207.1K0.00%−74,832−85.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.11,864$200.6K0.00%−143−1.2%Reduced
Quantum Private Wealth, LLC11,500$194.5K0.06%00.0%Unchanged
Envestnet Asset Management Inc10,944$185.1K0.00%−433−3.8%Reduced
Jump Financial, LLC10,551$178.4K0.00%+10,551New
Man Group plc10,473$177.1K0.00%−2,176−17.2%Reduced
Northwestern Mutual Wealth Management Co10,000$169.1K0.00%00.0%Unchanged
Quantbot Technologies LP9,357$158.2K0.01%−2,175−18.9%Reduced
State of Wyoming8,161$138.0K0.02%+2,721+50.0%Added
New York State Common Retirement Fund8,100$137.0K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey7,209$121.9K0.00%00.0%Unchanged
State of Alaska, Department of Revenue6,943$117.0K0.00%+5,522+388.6%Added
SG Americas Securities, LLC6,471$109.0K0.00%+6,471New
China Universal Asset Management Co., Ltd.4,370$73.9K0.01%+4,370New
Quest Partners LLC4,149$70.2K0.00%−10.0%Reduced
FMR LLC3,076$52.0K0.00%−2,618−46.0%Reduced
Tower Research Capital LLC (TRC)2,994$50.6K0.00%+2,023+208.3%Added
Caitong International Asset Management Co., Ltd2,939$49.7K0.01%+2,939New
Legal & General Group Plc2,731$46.2K0.00%−121−4.2%Reduced
Ameritas Investment Partners, Inc.2,167$36.6K0.00%00.0%Unchanged
California State Teachers Retirement System1,578$26.7K0.00%−23−1.4%Reduced
Citigroup Inc1,451$24.5K0.00%+240+19.8%Added
Mirae Asset Global Investments Co., Ltd.1,303$22.0K0.00%+1,303New
Truvestments Capital LLC1,183$20.0K0.00%00.0%Unchanged
Royal Bank of Canada1,018$17.0K0.00%−478,175−99.8%Reduced
Amalgamated Bank805$14.0K0.00%−71−8.1%Reduced
GF Fund Management Co. Ltd.527$8.91K0.00%+527New
Group One Trading, L.P.500$8.46K0.00%−262−34.4%Reduced
Jones Financial Companies LLLP221$3.74K0.00%+221New
Advisor Group Holdings, Inc.200$3.38K0.00%00.0%Unchanged
Sterling Capital Management LLC167$2.82K0.00%+105+169.4%Added
Vermillion & White Wealth Management Group, LLC150$2.54K0.00%00.0%Unchanged
Farther Finance Advisors, LLC146$2.47K0.00%+146New
Daiwa Securities Group Inc.89$2.00K0.00%+89New
US Bancorp54$9130.00%+54New
The PNC Financial Services Group, Inc.51$8620.00%+34+200.0%Added
GAMMA Investing LLC23$3890.00%+23New