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Enliven Therapeutics, Inc.

ELVN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001672619

In the last 90 days, Enliven Therapeutics, Inc. insiders filed 0 open-market purchases and 8 sales; 214 institutions reported holding it in 13F filings for Q2 2026, worth $4.06B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Enliven Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
−6 vs. Q3 2025
Shares held
62.4M
+3.00M (+5.0%) vs. Q3 2025
Total value
$960.9M
−$254.7M (−21.0%) vs. Q3 2025
New holders
20
46 more added
Sold out
26
45 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ELVN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 126 institutions
Q1 2021: 40 institutionsQ2 2021: 31 institutionsQ3 2021: 38 institutionsQ4 2021: 35 institutionsQ1 2022: 31 institutionsQ2 2022: 26 institutionsQ3 2022: 31 institutionsQ4 2022: 36 institutionsQ1 2023: 45 institutionsQ2 2023: 63 institutionsQ3 2023: 61 institutionsQ4 2023: 62 institutionsQ1 2024: 74 institutionsQ2 2024: 93 institutionsQ3 2024: 102 institutionsQ4 2024: 114 institutionsQ1 2025: 122 institutionsQ2 2025: 125 institutionsQ3 2025: 134 institutionsQ4 2025: 126 institutionsQ1 2026: 171 institutionsQ2 2026: 214 institutions
Value heldQ4 2025: $960.9M
Q1 2021: $92.9MQ2 2021: $86.3MQ3 2021: $62.5MQ4 2021: $33.6MQ1 2022: $26.2MQ2 2022: $13.1MQ3 2022: $18.8MQ4 2022: $74.7MQ1 2023: $735.0MQ2 2023: $797.9MQ3 2023: $533.8MQ4 2023: $539.8MQ1 2024: $780.8MQ2 2024: $1.13BQ3 2024: $1.22BQ4 2024: $1.12BQ1 2025: $983.9MQ2 2025: $1.19BQ3 2025: $1.22BQ4 2025: $960.9MQ1 2026: $2.43BQ2 2026: $4.06B
Institutions holding ELVN and their total value by quarter
QuarterHoldersValue
Q2 2026214$4.06B
Q1 2026171$2.43B
Q4 2025126$960.9M
Q3 2025134$1.22B
Q2 2025125$1.19B
Q1 2025122$983.9M
Q4 2024114$1.12B
Q3 2024102$1.22B
Q2 202493$1.13B
Q1 202474$780.8M
Q4 202362$539.8M
Q3 202361$533.8M
Q2 202363$797.9M
Q1 202345$735.0M
Q4 202236$74.7M
Q3 202231$18.8M
Q2 202226$13.1M
Q1 202231$26.2M
Q4 202135$33.6M
Q3 202138$62.5M
Q2 202131$86.3M
Q1 202140$92.9M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Enliven Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding ELVN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC7,959,538$122.6M2.51%00.0%Unchanged
FMR LLC7,107,635$109.5M0.01%−21,561−0.3%Reduced
Commodore Capital LP4,692,809$72.3M4.81%00.0%Unchanged
Vestal Point Capital, LP3,830,000$59.0M2.16%+2,670,000+230.2%Added
Fairmount Funds Management LLC3,711,444$57.2M4.35%00.0%Unchanged
BlackRock, Inc.3,613,326$55.6M0.00%+94,802+2.7%Added
Polar Capital Holdings Plc3,513,680$54.1M0.25%+418,673+13.5%Added
VR Adviser, LLC3,226,331$49.7M2.45%00.0%Unchanged
Vanguard Group Inc2,801,665$43.1M0.00%+248,651+9.7%Added
Janus Henderson Group PLC1,671,724$25.7M0.01%−121,859−6.8%Reduced
Point72 Asset Management, L.P.1,504,601$23.2M0.04%+464,191+44.6%Added
Novo Holdings A/S1,480,000$22.8M1.77%+53,740+3.8%Added
Citadel Advisors LLC1,424,344$21.9M0.01%+263,841+22.7%Added
Capital Research Global Investors1,304,346$20.1M0.00%−11,119−0.8%Reduced
Pictet Asset Management Holding SA1,303,235$20.1M0.02%−94,852−6.8%Reduced
State Street Corp1,052,862$16.2M0.00%+87,725+9.1%Added
Geode Capital Management, LLC1,048,722$16.2M0.00%−36,291−3.3%Reduced
Soleus Capital Management, L.P.1,025,000$15.8M0.67%+1,025,000New
Blackstone Group Inc.954,946$14.7M0.06%−365,646−27.7%Reduced
Rock Springs Capital Management LP798,405$12.3M0.63%+112,298+16.4%Added
5AM Venture Management, LLC772,477$11.9M3.74%00.0%Unchanged
Candriam Luxembourg S.C.A.453,019$6.98M0.03%−156,333−25.7%Reduced
Spruce Street Capital LP446,084$6.87M2.27%+446,084New
Morgan Stanley411,823$6.34M0.00%+153,439+59.4%Added
Dimensional Fund Advisors LP398,893$6.14M0.00%+238,434+148.6%Added
Marshall Wace, LLP371,906$5.73M0.01%+31,424+9.2%Added
Charles Schwab Investment Management Inc355,192$5.47M0.00%−8,010−2.2%Reduced
Northern Trust Corp352,239$5.42M0.00%−42,213−10.7%Reduced
Logos Global Management LP340,000$5.24M0.35%00.0%Unchanged
Patient Square Capital LP308,141$4.75M1.02%+57,303+22.8%Added
Woodline Partners LP301,023$4.64M0.02%+524+0.2%Added
Millennium Management LLC296,947$4.57M0.00%−84,458−22.1%Reduced
Baker Bros. Advisors LP271,406$4.18M0.02%+156,573+136.3%Added
Goldman Sachs Group Inc237,204$3.65M0.00%−25,068−9.6%Reduced
Sphera Funds Management Ltd.226,765$3.49M0.73%+60,000+36.0%Added
Exome Asset Management LLC222,308$3.42M1.69%+222,308New
Trails Edge Capital Partners, LP199,306$3.07M0.76%+199,306New
Connor, Clark & Lunn Investment Management Ltd.194,735$3.00M0.01%+159,956+459.9%Added
Avidity Partners Management LP140,300$2.16M0.62%00.0%Unchanged
Wellington Management Group LLP129,876$2.00M0.00%+21,316+19.6%Added
Bank of New York Mellon Corp110,569$1.70M0.00%−5,047−4.4%Reduced
Nuveen, LLC105,448$1.62M0.00%−2,796−2.6%Reduced
Jane Street Group, LLC101,971$1.57M0.00%+101,971New
Seven Fleet Capital Management LP99,953$1.54M1.04%+99,953New
HighVista Strategies LLC82,536$1.27M0.33%−176,599−68.1%Reduced
Barclays PLC69,875$1.08M0.00%−814−1.2%Reduced
Lighthouse Investment Partners, LLC65,000$1.00M0.03%+65,000New
Swiss National Bank64,273$989.8K0.00%+1,100+1.7%Added
XTX Topco Ltd60,702$934.8K0.02%+50,101+472.6%Added
ExodusPoint Capital Management, LP60,415$930.4K0.01%+12,280+25.5%Added
UBS Group AG57,868$891.2K0.00%−21,640−27.2%Reduced
UBS Asset Management Americas Inc55,210$850.2K0.00%+3,527+6.8%Added
Prelude Capital Management, LLC52,578$809.7K0.06%+52,578New
Rhumbline Advisers50,509$777.8K0.00%−9,651−16.0%Reduced
Susquehanna Portfolio Strategies, LLC48,741$750.6K0.01%+17,002+53.6%Added
American Century Companies Inc45,792$705.2K0.00%+34,283+297.9%Added
Jump Financial, LLC45,354$698.5K0.01%+45,354New
Wells Fargo & Company43,056$663.1K0.00%+17,232+66.7%Added
Alliancebernstein L.P.36,840$567.3K0.00%00.0%Unchanged
Prudential Financial Inc35,580$547.9K0.00%+35,580New
Bank of America Corp32,711$503.7K0.00%+9,168+38.9%Added
California State Teachers Retirement System32,206$496.0K0.00%+11,870+58.4%Added
Deutsche Bank AG31,420$483.9K0.00%+6,231+24.7%Added
ADAR1 Capital Management, LLC30,000$462.0K0.03%+30,000New
Tudor Investment Corp Et Al29,673$457.0K0.00%+13,370+82.0%Added
Aquatic Capital Management LLC27,955$430.5K0.01%+27,955New
Legal & General Group Plc27,059$416.7K0.00%−6,706−19.9%Reduced
Invesco Ltd.24,720$380.7K0.00%+1,624+7.0%Added
MetLife Investment Management24,556$378.2K0.00%00.0%Unchanged
Price T Rowe Associates Inc23,800$367.0K0.00%−207,504−89.7%Reduced
Squarepoint Ops LLC20,763$319.8K0.00%−15,082−42.1%Reduced
JPMorgan Chase & Co20,701$318.8K0.00%−4,117−16.6%Reduced
State of Wisconsin Investment Board20,398$314.1K0.00%−27,274−57.2%Reduced
Franklin Resources Inc20,167$310.6K0.00%−410,073−95.3%Reduced
Manufacturers Life Insurance Company, The19,336$297.8K0.00%−24,668−56.1%Reduced
Ameriprise Financial Inc18,949$291.8K0.00%−104,387−84.6%Reduced
Citigroup Inc18,489$284.7K0.00%+6,743+57.4%Added
Mirae Asset Global ETFs Holdings Ltd.18,287$281.6K0.00%−1,242−6.4%Reduced
Intech Investment Management LLC16,729$257.6K0.00%+2,256+15.6%Added
Virtus Investment Advisers, Inc.15,778$243.0K0.07%+9,991+172.6%Added
Axq Capital, LP14,244$219.4K0.05%+14,244New
SG Americas Securities, LLC14,035$216.0K0.00%−8,207−36.9%Reduced
Fox Run Management, L.L.C.12,432$191.5K0.03%+12,432New
Police & Firemen's Retirement System of New Jersey11,162$171.9K0.00%+123+1.1%Added
Canada Pension Plan Investment Board10,800$166.3K0.00%+10,800New
State Board of Administration of Florida Retirement System10,480$161.4K0.00%00.0%Unchanged
Quest Partners LLC10,337$159.2K0.01%+5,636+119.9%Added
Landscape Capital Management, L.L.C.10,301$158.6K0.01%00.0%Unchanged
Profund Advisors LLC10,179$156.8K0.00%+10,179New
BNP Paribas Arbitrage, SA9,672$148.9K0.00%+528+5.8%Added
China Universal Asset Management Co., Ltd.9,671$148.9K0.01%−712−6.9%Reduced
New York State Common Retirement Fund9,097$140.1K0.00%−6,000−39.7%Reduced
Los Angeles Capital Management LLC5,409$129.7K0.00%+5,409New
KLP Kapitalforvaltning AS6,800$104.7K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)6,163$94.9K0.00%+6,163New
Ameritas Investment Partners, Inc.3,449$53.1K0.00%00.0%Unchanged
Russell Investments Group, Ltd.3,121$48.1K0.00%−521−14.3%Reduced
Mirae Asset Global Investments Co., Ltd.2,884$44.4K0.00%+594+25.9%Added
Simplex Trading, LLC2,649$40.8K0.00%+2,480+1,467.5%Added
Tower Research Capital LLC (TRC)2,304$35.5K0.00%+728+46.2%Added