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Dyne Therapeutics, Inc.

DYN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001818794

In the last 90 days, Dyne Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 245 institutions reported holding it in 13F filings for Q2 2026, worth $4.23B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Dyne Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
233
+31 vs. Q3 2025
Shares held
177.9M
+23.0M (+14.8%) vs. Q3 2025
Total value
$3.48B
+$1.52B (+77.5%) vs. Q3 2025
New holders
59
96 more added
Sold out
28
58 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DYN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 233 institutions
Q1 2021: 75 institutionsQ2 2021: 76 institutionsQ3 2021: 83 institutionsQ4 2021: 93 institutionsQ1 2022: 94 institutionsQ2 2022: 90 institutionsQ3 2022: 102 institutionsQ4 2022: 113 institutionsQ1 2023: 127 institutionsQ2 2023: 118 institutionsQ3 2023: 114 institutionsQ4 2023: 124 institutionsQ1 2024: 169 institutionsQ2 2024: 193 institutionsQ3 2024: 200 institutionsQ4 2024: 200 institutionsQ1 2025: 205 institutionsQ2 2025: 198 institutionsQ3 2025: 207 institutionsQ4 2025: 233 institutionsQ1 2026: 228 institutionsQ2 2026: 245 institutions
Value heldQ4 2025: $3.48B
Q1 2021: $533.3MQ2 2021: $753.4MQ3 2021: $572.8MQ4 2021: $568.3MQ1 2022: $456.6MQ2 2022: $320.7MQ3 2022: $565.8MQ4 2022: $576.2MQ1 2023: $628.7MQ2 2023: $665.9MQ3 2023: $536.6MQ4 2023: $930.0MQ1 2024: $2.71BQ2 2024: $3.92BQ3 2024: $4.03BQ4 2024: $2.63BQ1 2025: $1.29BQ2 2025: $1.22BQ3 2025: $1.97BQ4 2025: $3.48BQ1 2026: $3.40BQ2 2026: $4.23B
Institutions holding DYN and their total value by quarter
QuarterHoldersValue
Q2 2026245$4.23B
Q1 2026228$3.40B
Q4 2025233$3.48B
Q3 2025207$1.97B
Q2 2025198$1.22B
Q1 2025205$1.29B
Q4 2024200$2.63B
Q3 2024200$4.03B
Q2 2024193$3.92B
Q1 2024169$2.71B
Q4 2023124$930.0M
Q3 2023114$536.6M
Q2 2023118$665.9M
Q1 2023127$628.7M
Q4 2022113$576.2M
Q3 2022102$565.8M
Q2 202290$320.7M
Q1 202294$456.6M
Q4 202193$568.3M
Q3 202183$572.8M
Q2 202176$753.4M
Q1 202175$533.3M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Dyne Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding DYN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Legato Capital Management LLC42,665$834.5K0.07%+42,665New
ADAR1 Capital Management, LLC42,674$834.7K0.06%+5,011+13.3%Added
Intech Investment Management LLC44,288$866.3K0.01%−8,762−16.5%Reduced
J. Goldman & Co LP46,010$900.0K0.03%+46,010New
Wellington Management Group LLP47,096$921.2K0.00%+5,181+12.4%Added
Arcadia Investment Management Corp47,875$936.4K0.15%−1,350−2.7%Reduced
Norges Bank49,319$964.7K0.00%+49,319New
Victory Capital Management Inc51,484$1.01M0.00%+1,382+2.8%Added
XTX Topco Ltd56,661$1.11M0.03%+27,446+93.9%Added
SEI Investments Co58,755$1.15M0.00%+58,755New
HighVista Strategies LLC59,643$1.17M0.30%+59,643New
State of Wisconsin Investment Board63,653$1.25M0.00%+23,694+59.3%Added
Manufacturers Life Insurance Company, The67,507$1.32M0.00%+10,164+17.7%Added
CIBC World Markets Inc.68,766$1.35M0.00%+68,766New
MetLife Investment Management69,599$1.36M0.01%+5,378+8.4%Added
Seven Fleet Capital Management LP70,180$1.37M0.93%+70,180New
Jane Street Group, LLC70,323$1.38M0.00%−211,017−75.0%Reduced
AQR Capital Management LLC70,659$1.38M0.00%−71,216−50.2%Reduced
Mirae Asset Global ETFs Holdings Ltd.71,191$1.39M0.00%+9,556+15.5%Added
Headlands Technologies LLC75,235$1.47M0.12%+62,536+492.4%Added
HRT Financial LP75,394$1.47M0.00%+75,394New
Aegis Wealth Management LLC75,908$1.48M0.84%+26,000+52.1%Added
New York State Common Retirement Fund79,262$1.55M0.00%+44,589+128.6%Added
Comerica Bank85,339$1.67M0.01%−1,157−1.3%Reduced
Voya Investment Management LLC86,438$1.69M0.00%−12,263−12.4%Reduced
Profund Advisors LLC86,746$1.70M0.05%+40,766+88.7%Added
DekaBank Deutsche Girozentrale60,000$1.86M0.00%00.0%Unchanged
Dimensional Fund Advisors LP98,074$1.92M0.00%+98,074New
Susquehanna International Group, LLP98,215$1.92M0.00%−19,555−16.6%Reduced
Trexquant Investment LP100,645$1.97M0.02%−244,817−70.9%Reduced
Baird Financial Group, Inc.103,334$2.02M0.00%+103,334New
Axxcess Wealth Management, LLC113,818$2.23M0.04%+113,818New
Monashee Investment Management LLC114,525$2.24M1.26%+114,525New
Darwin Advisors, LLC115,267$2.25M0.70%−58,250−33.6%Reduced
Legal & General Group Plc118,122$2.31M0.00%+10,147+9.4%Added
Vestal Point Capital, LP120,000$2.35M0.09%−2,655,000−95.7%Reduced
Woodline Partners LP120,788$2.36M0.01%+120,788New
California State Teachers Retirement System120,800$2.36M0.00%+31,640+35.5%Added
Alliancebernstein L.P.134,260$2.63M0.00%+27,580+25.9%Added
Invesco Ltd.137,684$2.69M0.00%+20,121+17.1%Added
Tudor Investment Corp Et Al147,621$2.89M0.02%+147,621New
Wells Fargo & Company147,831$2.89M0.00%+60,710+69.7%Added
Lisanti Capital Growth, LLC154,445$3.02M0.72%+154,445New
Burkehill Global Management, LP155,000$3.03M0.20%+35,000+29.2%Added
First Light Asset Management, LLC155,231$3.04M0.23%+155,231New
Brevan Howard Capital Management LP157,969$3.09M0.06%+98,667+166.4%Added
Jain Global LLC162,047$3.17M0.03%−482,035−74.8%Reduced
Neuberger Berman Group LLC165,482$3.24M0.00%−155,944−48.5%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.165,692$3.24M0.00%+164,846+19,485.3%Added
American Century Companies Inc168,304$3.29M0.00%+136,919+436.3%Added
Rhumbline Advisers175,020$3.42M0.00%+7,200+4.3%Added
PDT Partners, LLC182,986$3.58M0.23%−18,254−9.1%Reduced
Deutsche Bank AG196,080$3.84M0.00%+70,194+55.8%Added
Ameriprise Financial Inc197,691$3.87M0.00%−224,965−53.2%Reduced
UBS Asset Management Americas Inc214,491$4.20M0.00%−14,939−6.5%Reduced
Swiss National Bank222,500$4.35M0.00%+44,200+24.8%Added
Russell Investments Group, Ltd.232,013$4.54M0.00%+118,081+103.6%Added
Rafferty Asset Management, LLC233,835$4.57M0.02%+20,624+9.7%Added
Neo Ivy Capital Management237,467$4.64M0.73%+237,467New
SummitTX Capital, L.P.243,276$4.76M0.14%+110,376+83.1%Added
Polygon Management Ltd.247,997$4.85M1.02%+24,816+11.1%Added
Fisher Asset Management, LLC250,065$4.89M0.00%+250,065New
Squarepoint Ops LLC255,160$4.99M0.01%+207,568+436.1%Added
SG Americas Securities, LLC265,384$5.19M0.01%+265,384New
Algert Global LLC271,303$5.31M0.08%−243,829−47.3%Reduced
Canada Pension Plan Investment Board284,000$5.56M0.00%00.0%Unchanged
Point72 Asset Management, L.P.329,345$6.44M0.01%−1,388,462−80.8%Reduced
Y-Intercept (Hong Kong) Ltd343,726$6.72M0.15%+343,726New
Bank of New York Mellon Corp353,497$6.91M0.00%+36,133+11.4%Added
Schroder Investment Management Group386,953$7.43M0.01%+111,357+40.4%Added
UBS Group AG380,978$7.45M0.00%+31,590+9.0%Added
Sphera Funds Management Ltd.392,894$7.69M1.61%−33,624−7.9%Reduced
Wasatch Advisors Inc406,960$7.96M0.05%−116,964−22.3%Reduced
Clearbridge Investments, LLC407,794$7.98M0.01%+407,794New
Qube Research & Technologies Ltd412,440$8.07M0.01%−417,329−50.3%Reduced
University of Wisconsin Foundation416,750$8.15M6.85%−101,000−19.5%Reduced
TD Asset Management Inc419,756$8.21M0.01%+399,374+1,959.4%Added
Balyasny Asset Management LLC432,986$8.47M0.02%+432,986New
Barclays PLC448,658$8.78M0.00%−32,043−6.7%Reduced
Federated Hermes, Inc.464,797$9.09M0.02%+464,797New
Renaissance Technologies LLC470,645$9.21M0.01%+125,145+36.2%Added
Ensign Peak Advisors, Inc496,590$9.71M0.02%+476,440+2,364.5%Added
Catalio Capital Management, LP519,715$10.2M1.80%+519,715New
Raymond James Financial Inc530,338$10.4M0.00%+453,426+589.5%Added
Nuveen, LLC621,310$12.2M0.00%+276,413+80.1%Added
Artisan Partners Limited Partnership649,691$12.7M0.02%+649,691New
Marshall Wace, LLP676,979$13.2M0.01%−2,336,398−77.5%Reduced
Eventide Asset Management, LLC680,305$13.3M0.21%+680,305New
ArrowMark Colorado Holdings LLC700,653$13.7M0.30%−85,262−10.8%Reduced
Baker Bros. Advisors LP813,449$15.9M0.09%+813,449New
StemPoint Capital LP835,200$16.3M2.80%+360,588+76.0%Added
Bank of America Corp882,922$17.3M0.00%+121,810+16.0%Added
Millennium Management LLC904,389$17.7M0.01%+490,449+118.5%Added
Rock Springs Capital Management LP912,955$17.9M0.92%+88,894+10.8%Added
Candriam Luxembourg S.C.A.1,057,263$20.7M0.10%+223,341+26.8%Added
Northern Trust Corp1,092,191$21.4M0.00%+54,623+5.3%Added
Standard Life Aberdeen plc1,108,145$21.7M0.03%+551,412+99.0%Added
Frontier Capital Management Co LLC1,138,868$22.3M0.24%+227,949+25.0%Added
Charles Schwab Investment Management Inc1,151,325$22.5M0.00%+144,131+14.3%Added
Citadel Advisors LLC1,171,624$22.9M0.02%−2,241,811−65.7%Reduced