Dyne Therapeutics, Inc.
DYN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001818794
In the last 90 days, Dyne Therapeutics, Inc. insiders filed 0 open-market purchases and 11 sales; 245 institutions reported holding it in 13F filings for Q2 2026, worth $4.23B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Dyne Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 233
- +31 vs. Q3 2025
- Shares held
- 177.9M
- +23.0M (+14.8%) vs. Q3 2025
- Total value
- $3.48B
- +$1.52B (+77.5%) vs. Q3 2025
- New holders
- 59
- 96 more added
- Sold out
- 28
- 58 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DYN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 245 | $4.23B |
| Q1 2026 | 228 | $3.40B |
| Q4 2025 | 233 | $3.48B |
| Q3 2025 | 207 | $1.97B |
| Q2 2025 | 198 | $1.22B |
| Q1 2025 | 205 | $1.29B |
| Q4 2024 | 200 | $2.63B |
| Q3 2024 | 200 | $4.03B |
| Q2 2024 | 193 | $3.92B |
| Q1 2024 | 169 | $2.71B |
| Q4 2023 | 124 | $930.0M |
| Q3 2023 | 114 | $536.6M |
| Q2 2023 | 118 | $665.9M |
| Q1 2023 | 127 | $628.7M |
| Q4 2022 | 113 | $576.2M |
| Q3 2022 | 102 | $565.8M |
| Q2 2022 | 90 | $320.7M |
| Q1 2022 | 94 | $456.6M |
| Q4 2021 | 93 | $568.3M |
| Q3 2021 | 83 | $572.8M |
| Q2 2021 | 76 | $753.4M |
| Q1 2021 | 75 | $533.3M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Dyne Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| T. Rowe Price Investment Management, Inc. | 17,540,089 | $343.1M | 0.22% | +14,727,667+523.7% | Added |
| Janus Henderson Group PLC | 13,887,722 | $271.6M | 0.12% | −857,783−5.8% | Reduced |
| Vanguard Group Inc | 11,215,565 | $219.4M | 0.00% | +1,455,151+14.9% | Added |
| BlackRock, Inc. | 11,190,838 | $218.9M | 0.00% | +1,555,929+16.1% | Added |
| Atlas Venture Life Science Advisors, LLC | 9,130,465 | $178.6M | 20.64% | 00.0% | Unchanged |
| State Street Corp | 6,692,745 | $130.9M | 0.00% | +1,423,828+27.0% | Added |
| FMR LLC | 6,569,921 | $128.5M | 0.01% | +1,168,005+21.6% | Added |
| FCPM III Services B.V. | 5,462,846 | $106.9M | 14.01% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 5,172,000 | $101.2M | 0.15% | +1,618,000+45.5% | Added |
| Orbis Allan Gray Ltd | 4,801,928 | $93.9M | 0.39% | +4,801,928 | New |
| TCG Crossover Management, LLC | 4,615,144 | $90.3M | 2.99% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 3,549,909 | $69.4M | 0.00% | +184,664+5.5% | Added |
| Siren, L.L.C. | 3,502,941 | $68.5M | 2.04% | −1,226,233−25.9% | Reduced |
| Perceptive Advisors LLC | 3,478,944 | $68.0M | 1.25% | +2,938,500+543.7% | Added |
| Geode Capital Management, LLC | 3,263,429 | $63.8M | 0.00% | +395,824+13.8% | Added |
| Armistice Capital, LLC | 3,249,708 | $63.6M | 1.56% | +185,708+6.1% | Added |
| Frazier Life Sciences Management, L.P. | 3,153,082 | $61.7M | 1.66% | +434,977+16.0% | Added |
| Deep Track Capital, LP | 2,650,000 | $51.8M | 1.18% | +650,000+32.5% | Added |
| Vivo Capital, LLC | 2,614,960 | $51.1M | 3.31% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 2,323,789 | $45.5M | 0.00% | +925,702+66.2% | Added |
| Goldman Sachs Group Inc | 2,283,191 | $44.7M | 0.01% | +382,976+20.2% | Added |
| Sofinnova Investments, Inc. | 2,254,161 | $44.1M | 1.90% | +1,268,333+128.7% | Added |
| OrbiMed Advisors LLC | 2,202,184 | $43.1M | 0.88% | −112,000−4.8% | Reduced |
| VR Adviser, LLC | 2,173,913 | $42.5M | 2.10% | 00.0% | Unchanged |
| Franklin Resources Inc | 2,006,638 | $39.2M | 0.01% | +608,108+43.5% | Added |
| Saturn V Capital Management LLC | 1,788,616 | $35.0M | 6.42% | −885,853−33.1% | Reduced |
| Samlyn Capital, LLC | 1,493,075 | $29.2M | 0.47% | +1,493,075 | New |
| Braidwell LP | 1,478,329 | $28.9M | 0.92% | −1,252,152−45.9% | Reduced |
| Palo Alto Investors LP | 1,472,197 | $28.8M | 4.01% | +209,523+16.6% | Added |
| MPM Oncology Impact Management LP | 1,405,388 | $27.5M | 3.15% | −40,973−2.8% | Reduced |
| Polar Capital Holdings Plc | 1,269,131 | $24.8M | 0.11% | +739,743+139.7% | Added |
| Logos Global Management LP | 1,250,000 | $24.4M | 1.63% | −1,150,000−47.9% | Reduced |
| Morgan Stanley | 1,213,559 | $23.7M | 0.00% | −205,448−14.5% | Reduced |
| Citadel Advisors LLC | 1,171,624 | $22.9M | 0.02% | −2,241,811−65.7% | Reduced |
| Charles Schwab Investment Management Inc | 1,151,325 | $22.5M | 0.00% | +144,131+14.3% | Added |
| Frontier Capital Management Co LLC | 1,138,868 | $22.3M | 0.24% | +227,949+25.0% | Added |
| Standard Life Aberdeen plc | 1,108,145 | $21.7M | 0.03% | +551,412+99.0% | Added |
| Northern Trust Corp | 1,092,191 | $21.4M | 0.00% | +54,623+5.3% | Added |
| Candriam Luxembourg S.C.A. | 1,057,263 | $20.7M | 0.10% | +223,341+26.8% | Added |
| Rock Springs Capital Management LP | 912,955 | $17.9M | 0.92% | +88,894+10.8% | Added |
| Millennium Management LLC | 904,389 | $17.7M | 0.01% | +490,449+118.5% | Added |
| Bank of America Corp | 882,922 | $17.3M | 0.00% | +121,810+16.0% | Added |
| StemPoint Capital LP | 835,200 | $16.3M | 2.80% | +360,588+76.0% | Added |
| Baker Bros. Advisors LP | 813,449 | $15.9M | 0.09% | +813,449 | New |
| ArrowMark Colorado Holdings LLC | 700,653 | $13.7M | 0.30% | −85,262−10.8% | Reduced |
| Eventide Asset Management, LLC | 680,305 | $13.3M | 0.21% | +680,305 | New |
| Marshall Wace, LLP | 676,979 | $13.2M | 0.01% | −2,336,398−77.5% | Reduced |
| Artisan Partners Limited Partnership | 649,691 | $12.7M | 0.02% | +649,691 | New |
| Nuveen, LLC | 621,310 | $12.2M | 0.00% | +276,413+80.1% | Added |
| Raymond James Financial Inc | 530,338 | $10.4M | 0.00% | +453,426+589.5% | Added |
| Catalio Capital Management, LP | 519,715 | $10.2M | 1.80% | +519,715 | New |
| Ensign Peak Advisors, Inc | 496,590 | $9.71M | 0.02% | +476,440+2,364.5% | Added |
| Renaissance Technologies LLC | 470,645 | $9.21M | 0.01% | +125,145+36.2% | Added |
| Federated Hermes, Inc. | 464,797 | $9.09M | 0.02% | +464,797 | New |
| Barclays PLC | 448,658 | $8.78M | 0.00% | −32,043−6.7% | Reduced |
| Balyasny Asset Management LLC | 432,986 | $8.47M | 0.02% | +432,986 | New |
| TD Asset Management Inc | 419,756 | $8.21M | 0.01% | +399,374+1,959.4% | Added |
| University of Wisconsin Foundation | 416,750 | $8.15M | 6.85% | −101,000−19.5% | Reduced |
| Qube Research & Technologies Ltd | 412,440 | $8.07M | 0.01% | −417,329−50.3% | Reduced |
| Clearbridge Investments, LLC | 407,794 | $7.98M | 0.01% | +407,794 | New |
| Wasatch Advisors Inc | 406,960 | $7.96M | 0.05% | −116,964−22.3% | Reduced |
| Sphera Funds Management Ltd. | 392,894 | $7.69M | 1.61% | −33,624−7.9% | Reduced |
| UBS Group AG | 380,978 | $7.45M | 0.00% | +31,590+9.0% | Added |
| Schroder Investment Management Group | 386,953 | $7.43M | 0.01% | +111,357+40.4% | Added |
| Bank of New York Mellon Corp | 353,497 | $6.91M | 0.00% | +36,133+11.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 343,726 | $6.72M | 0.15% | +343,726 | New |
| Point72 Asset Management, L.P. | 329,345 | $6.44M | 0.01% | −1,388,462−80.8% | Reduced |
| Canada Pension Plan Investment Board | 284,000 | $5.56M | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 271,303 | $5.31M | 0.08% | −243,829−47.3% | Reduced |
| SG Americas Securities, LLC | 265,384 | $5.19M | 0.01% | +265,384 | New |
| Squarepoint Ops LLC | 255,160 | $4.99M | 0.01% | +207,568+436.1% | Added |
| Fisher Asset Management, LLC | 250,065 | $4.89M | 0.00% | +250,065 | New |
| Polygon Management Ltd. | 247,997 | $4.85M | 1.02% | +24,816+11.1% | Added |
| SummitTX Capital, L.P. | 243,276 | $4.76M | 0.14% | +110,376+83.1% | Added |
| Neo Ivy Capital Management | 237,467 | $4.64M | 0.73% | +237,467 | New |
| Rafferty Asset Management, LLC | 233,835 | $4.57M | 0.02% | +20,624+9.7% | Added |
| Russell Investments Group, Ltd. | 232,013 | $4.54M | 0.00% | +118,081+103.6% | Added |
| Swiss National Bank | 222,500 | $4.35M | 0.00% | +44,200+24.8% | Added |
| UBS Asset Management Americas Inc | 214,491 | $4.20M | 0.00% | −14,939−6.5% | Reduced |
| Ameriprise Financial Inc | 197,691 | $3.87M | 0.00% | −224,965−53.2% | Reduced |
| Deutsche Bank AG | 196,080 | $3.84M | 0.00% | +70,194+55.8% | Added |
| PDT Partners, LLC | 182,986 | $3.58M | 0.23% | −18,254−9.1% | Reduced |
| Rhumbline Advisers | 175,020 | $3.42M | 0.00% | +7,200+4.3% | Added |
| American Century Companies Inc | 168,304 | $3.29M | 0.00% | +136,919+436.3% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 165,692 | $3.24M | 0.00% | +164,846+19,485.3% | Added |
| Neuberger Berman Group LLC | 165,482 | $3.24M | 0.00% | −155,944−48.5% | Reduced |
| Jain Global LLC | 162,047 | $3.17M | 0.03% | −482,035−74.8% | Reduced |
| Brevan Howard Capital Management LP | 157,969 | $3.09M | 0.06% | +98,667+166.4% | Added |
| First Light Asset Management, LLC | 155,231 | $3.04M | 0.23% | +155,231 | New |
| Burkehill Global Management, LP | 155,000 | $3.03M | 0.20% | +35,000+29.2% | Added |
| Lisanti Capital Growth, LLC | 154,445 | $3.02M | 0.72% | +154,445 | New |
| Wells Fargo & Company | 147,831 | $2.89M | 0.00% | +60,710+69.7% | Added |
| Tudor Investment Corp Et Al | 147,621 | $2.89M | 0.02% | +147,621 | New |
| Invesco Ltd. | 137,684 | $2.69M | 0.00% | +20,121+17.1% | Added |
| Alliancebernstein L.P. | 134,260 | $2.63M | 0.00% | +27,580+25.9% | Added |
| California State Teachers Retirement System | 120,800 | $2.36M | 0.00% | +31,640+35.5% | Added |
| Woodline Partners LP | 120,788 | $2.36M | 0.01% | +120,788 | New |
| Vestal Point Capital, LP | 120,000 | $2.35M | 0.09% | −2,655,000−95.7% | Reduced |
| Legal & General Group Plc | 118,122 | $2.31M | 0.00% | +10,147+9.4% | Added |
| Darwin Advisors, LLC | 115,267 | $2.25M | 0.70% | −58,250−33.6% | Reduced |