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Dyne Therapeutics, Inc.

DYN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001818794

In the last 90 days, Dyne Therapeutics, Inc. insiders filed 0 open-market purchases and 11 sales; 245 institutions reported holding it in 13F filings for Q2 2026, worth $4.23B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Dyne Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
207
+12 vs. Q2 2025
Shares held
155.8M
+27.3M (+21.2%) vs. Q2 2025
Total value
$1.97B
+$749.0M (+61.2%) vs. Q2 2025
New holders
38
112 more added
Sold out
26
38 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DYN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 207 institutions
Q1 2021: 75 institutionsQ2 2021: 76 institutionsQ3 2021: 83 institutionsQ4 2021: 93 institutionsQ1 2022: 94 institutionsQ2 2022: 90 institutionsQ3 2022: 102 institutionsQ4 2022: 113 institutionsQ1 2023: 127 institutionsQ2 2023: 118 institutionsQ3 2023: 114 institutionsQ4 2023: 124 institutionsQ1 2024: 169 institutionsQ2 2024: 193 institutionsQ3 2024: 200 institutionsQ4 2024: 200 institutionsQ1 2025: 205 institutionsQ2 2025: 198 institutionsQ3 2025: 207 institutionsQ4 2025: 233 institutionsQ1 2026: 228 institutionsQ2 2026: 245 institutions
Value heldQ3 2025: $1.97B
Q1 2021: $533.3MQ2 2021: $753.4MQ3 2021: $572.8MQ4 2021: $568.3MQ1 2022: $456.6MQ2 2022: $320.7MQ3 2022: $565.8MQ4 2022: $576.2MQ1 2023: $628.7MQ2 2023: $665.9MQ3 2023: $536.6MQ4 2023: $930.0MQ1 2024: $2.71BQ2 2024: $3.92BQ3 2024: $4.03BQ4 2024: $2.63BQ1 2025: $1.29BQ2 2025: $1.22BQ3 2025: $1.97BQ4 2025: $3.48BQ1 2026: $3.40BQ2 2026: $4.23B
Institutions holding DYN and their total value by quarter
QuarterHoldersValue
Q2 2026245$4.23B
Q1 2026228$3.40B
Q4 2025233$3.48B
Q3 2025207$1.97B
Q2 2025198$1.22B
Q1 2025205$1.29B
Q4 2024200$2.63B
Q3 2024200$4.03B
Q2 2024193$3.92B
Q1 2024169$2.71B
Q4 2023124$930.0M
Q3 2023114$536.6M
Q2 2023118$665.9M
Q1 2023127$628.7M
Q4 2022113$576.2M
Q3 2022102$565.8M
Q2 202290$320.7M
Q1 202294$456.6M
Q4 202193$568.3M
Q3 202183$572.8M
Q2 202176$753.4M
Q1 202175$533.3M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Dyne Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding DYN in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC14,745,505$186.5M0.09%+5,307,543+56.2%Added
Vanguard Group Inc9,760,414$123.5M0.00%+2,109,257+27.6%Added
BlackRock, Inc.9,634,909$121.9M0.00%+1,556,481+19.3%Added
Atlas Venture Life Science Advisors, LLC9,130,465$115.5M15.35%00.0%Unchanged
FCPM III Services B.V.5,462,846$69.1M13.81%00.0%Unchanged
FMR LLC5,401,916$68.3M0.00%+108,547+2.1%Added
State Street Corp5,268,917$66.7M0.00%+1,913,239+57.0%Added
Siren, L.L.C.4,729,174$59.8M2.34%−107,263−2.2%Reduced
TCG Crossover Management, LLC4,615,144$58.4M2.87%+848,484+22.5%Added
Adage Capital Partners GP, L.L.C.3,554,000$45.0M0.07%+363,000+11.4%Added
Citadel Advisors LLC3,413,435$43.2M0.03%+2,469,561+261.6%Added
JPMorgan Chase & Co3,365,245$42.6M0.00%+278,466+9.0%Added
Armistice Capital, LLC3,064,000$38.8M1.22%+504,000+19.7%Added
Marshall Wace, LLP3,013,377$38.1M0.04%+2,565,570+572.9%Added
RTW Investments, LP2,890,567$36.6M0.45%+1,200,000+71.0%Added
Geode Capital Management, LLC2,867,605$36.3M0.00%+613,935+27.2%Added
T. Rowe Price Investment Management, Inc.2,812,422$35.6M0.02%+1,018,832+56.8%Added
Vestal Point Capital, LP2,775,000$35.1M1.59%+2,047,500+281.4%Added
Braidwell LP2,730,481$34.5M1.02%−542,868−16.6%Reduced
Frazier Life Sciences Management, L.P.2,718,105$34.4M1.03%+1,212,121+80.5%Added
Saturn V Capital Management LLC2,674,469$33.8M7.42%+1,219,040+83.8%Added
Vivo Capital, LLC2,614,960$33.1M2.66%+1,500,000+134.5%Added
Logos Global Management LP2,400,000$30.4M3.00%+500,000+26.3%Added
OrbiMed Advisors LLC2,314,184$29.3M0.70%+1,282,784+124.4%Added
VR Adviser, LLC2,173,913$27.5M1.55%00.0%Unchanged
Deep Track Capital, LP2,000,000$25.3M0.71%+2,000,000New
Goldman Sachs Group Inc1,900,215$24.0M0.00%+559,772+41.8%Added
Paradigm Biocapital Advisors LP1,898,950$24.0M0.71%+1,898,950New
Point72 Asset Management, L.P.1,717,807$21.7M0.05%+1,594,523+1,293.4%Added
MPM Oncology Impact Management LP1,446,361$18.3M3.00%00.0%Unchanged
Morgan Stanley1,419,007$18.0M0.00%+56,831+4.2%Added
Franklin Resources Inc1,398,530$17.7M0.00%+8,390+0.6%Added
Price T Rowe Associates Inc1,398,087$17.7M0.00%−985,866−41.4%Reduced
Palo Alto Investors LP1,262,674$16.0M2.96%+997,698+376.5%Added
Northern Trust Corp1,037,568$13.1M0.00%+196,531+23.4%Added
Charles Schwab Investment Management Inc1,007,194$12.7M0.00%+262,123+35.2%Added
Sofinnova Investments, Inc.985,828$12.5M0.77%+370,963+60.3%Added
Frontier Capital Management Co LLC910,919$11.5M0.10%+121,494+15.4%Added
Candriam Luxembourg S.C.A.833,922$10.5M0.06%+309,761+59.1%Added
Qube Research & Technologies Ltd829,769$10.5M0.01%+37,782+4.8%Added
Rock Springs Capital Management LP824,061$10.4M0.61%+243,063+41.8%Added
Integral Health Asset Management, LLC800,000$10.1M0.74%+800,000New
ArrowMark Colorado Holdings LLC785,915$9.94M0.18%+15,690+2.0%Added
Bank of America Corp761,112$9.63M0.00%+247,311+48.1%Added
Jacobs Levy Equity Management, Inc729,606$9.23M0.04%+729,606New
Voloridge Investment Management, LLC710,044$8.98M0.03%−81,076−10.2%Reduced
Nantahala Capital Management, LLC702,884$8.89M0.55%−42,178−5.7%Reduced
MPM Asset Management LLC682,376$8.63M19.40%00.0%Unchanged
Jain Global LLC644,082$8.15M0.11%+47,915+8.0%Added
Standard Life Aberdeen plc556,733$7.04M0.01%+72,770+15.0%Added
Royal Bank of Canada543,166$6.87M0.00%+168,197+44.9%Added
Perceptive Advisors LLC540,444$6.84M0.20%−1,706,946−76.0%Reduced
Polar Capital Holdings Plc529,388$6.70M0.03%+529,388New
Wasatch Advisors Inc523,924$6.63M0.04%−34,013−6.1%Reduced
University of Wisconsin Foundation517,750$6.55M5.55%+517,750New
Algert Global LLC515,132$6.52M0.11%−43,764−7.8%Reduced
Barclays PLC480,701$6.08M0.00%+160,211+50.0%Added
StemPoint Capital LP474,612$6.00M1.21%+474,612New
Sphera Funds Management Ltd.426,518$5.40M1.28%+205,102+92.6%Added
Ameriprise Financial Inc422,656$5.35M0.00%+137,652+48.3%Added
Schonfeld Strategic Advisors LLC415,927$5.26M0.04%+82,474+24.7%Added
Millennium Management LLC413,940$5.24M0.00%+271,221+190.0%Added
UBS Group AG349,388$4.42M0.00%+227,596+186.9%Added
Renaissance Technologies LLC345,500$4.37M0.01%+345,500New
Trexquant Investment LP345,462$4.37M0.05%−16,848−4.7%Reduced
Nuveen, LLC344,897$4.36M0.00%+145,066+72.6%Added
Neuberger Berman Group LLC321,426$4.07M0.00%+121,160+60.5%Added
Bank of New York Mellon Corp317,364$4.01M0.00%+47,700+17.7%Added
Canada Pension Plan Investment Board284,000$3.59M0.00%+284,000New
Jane Street Group, LLC281,340$3.56M0.00%+152,378+118.2%Added
Schroder Investment Management Group275,596$3.41M0.00%+69,970+34.0%Added
UBS Asset Management Americas Inc229,430$2.90M0.00%−64,214−21.9%Reduced
Polygon Management Ltd.223,181$2.82M0.41%+84,806+61.3%Added
Rafferty Asset Management, LLC213,211$2.70M0.01%+102,963+93.4%Added
PDT Partners, LLC201,240$2.55M0.16%−184,008−47.8%Reduced
Swiss National Bank178,300$2.26M0.00%+37,900+27.0%Added
Darwin Advisors, LLC173,517$2.19M0.70%+861+0.5%Added
Rhumbline Advisers167,820$2.12M0.00%+13,279+8.6%Added
AXA Investment Managers S.A.163,231$2.06M0.01%+163,231New
DekaBank Deutsche Girozentrale60,000$1.84M0.00%00.0%Unchanged
AQR Capital Management LLC141,875$1.79M0.00%+98,965+230.6%Added
BNP Paribas Arbitrage, SA136,385$1.73M0.00%−140,874−50.8%Reduced
SummitTX Capital, L.P.132,900$1.68M0.07%+13,939+11.7%Added
Deutsche Bank AG125,886$1.59M0.00%−192,767−60.5%Reduced
Burkehill Global Management, LP120,000$1.52M0.09%+120,000New
Susquehanna International Group, LLP117,770$1.49M0.00%−68,245−36.7%Reduced
Invesco Ltd.117,563$1.49M0.00%+35,421+43.1%Added
Twinbeech Capital LP115,341$1.46M0.06%−81,807−41.5%Reduced
Russell Investments Group, Ltd.113,932$1.44M0.00%+70,007+159.4%Added
Ikarian Capital, LLC113,837$1.44M0.33%−250,000−68.7%Reduced
Voleon Capital Management LP111,838$1.41M0.03%+67,115+150.1%Added
Legal & General Group Plc107,975$1.37M0.00%+29,442+37.5%Added
Alliancebernstein L.P.106,680$1.35M0.00%+8,440+8.6%Added
Engineers Gate Manager LP102,991$1.30M0.01%−69,478−40.3%Reduced
Silverarc Capital Management, LLC100,000$1.26M0.18%+100,000New
Jump Financial, LLC99,884$1.26M0.02%+99,884New
Voya Investment Management LLC98,701$1.25M0.00%+45,527+85.6%Added
California State Teachers Retirement System89,160$1.13M0.00%−12,452−12.3%Reduced
Wells Fargo & Company87,121$1.10M0.00%+30,416+53.6%Added
Comerica Bank86,496$1.09M0.00%+11,158+14.8%Added