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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Denali Therapeutics Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
0 filings
Open-market sells
4 filings
3 insiders, $435.3K in total
Insiders trading
3
Net value
−$435.3K
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Denali Therapeutics Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Denali Therapeutics Inc.
NameTitleLast reported holdingLast filingFilings, past year
Chin Peter ScottChief Medical Officer204,538Sep 9, 20261
Thornberry NancyDirector19,686Sep 4, 20262
Schuth Alexander O.COFO and Secretary278,995Sep 3, 20264
Watts Ryan J.President and CEO2,120,384IndirectAug 14, 20263
Baker JulianDirector3,422,366IndirectJun 5, 20262
Baker FelixDirector3,422,366IndirectJun 5, 20262
Baker Bros. Advisors LPDirector3,422,366IndirectJun 5, 20262
Baker Brothers Life Sciences LPDirector3,422,366IndirectJun 5, 20262
667, L.P.Director3,422,366IndirectJun 5, 20262
Baker Bros. Advisors (GP) LLCDirector3,422,366IndirectJun 5, 20262
Flatley Jay TDirector22,628Jun 5, 20261
Klein Peter SDirector33,941Jun 5, 20261
Schenkein David PDirector21,665Jun 5, 20261
Krognes Steve E.Director38,202Jun 5, 20261
Cook Jennifer E.Director32,483Jun 5, 20261
Van Hauwermeiren TimothyDirector17,040Jun 5, 20262
Ho CaroleChief Medical Officer216,585Aug 14, 20250
Tessier-Lavigne MarcDirector1,886,576Jun 5, 20250
Sato Vicki LDirector107,976Jan 3, 20250
Harris ErikDirector17,052Jun 4, 20240
Cole Douglas G.Director26,564Jun 5, 20230

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 6, 2021 (view filing)Jul 15 daysWatts Ryan J.President and CEOSSale−18.3K$77.26−$1.42M−0.8%2.19M after3 lots
Jul 8, 2021 (view filing)Jul 62 daysSchuth Alexander O.COO and SecretarySSale−10.0K$76.20−$762.0K−2.0%491.6K after
Jul 23, 2021 (view filing)Jul 212 daysSato Vicki LDirectorSSale−1.67K$65.13−$108.5K−1.2%132.8K after3 lots
Aug 4, 2021 (view filing)Aug 22 daysWatts Ryan J.President and CEOSSale−18.3K$51.41−$942.5K−0.8%2.17M after2 lots
Aug 6, 2021 (view filing)Aug 42 daysSchuth Alexander O.COO and SecretarySSale−10.0K$52.22−$522.2K−2.0%481.6K after3 lots
Aug 20, 2021 (view filing)Aug 182 daysSato Vicki LDirectorSSale−1.67K$51.70−$86.1K−1.3%131.2K after2 lots
Aug 23, 2021 (view filing)Aug 194 daysKrognes Steve E.CFO and TreasurerSSale−2.29K$49.57−$113.3K−2.3%95.3K after2 lots
Aug 23, 2021 (view filing)Aug 194 daysWatts Ryan J.President and CEOSSale−2.38K$49.57−$117.8K−0.1%2.18M after2 lots
Aug 23, 2021 (view filing)Aug 194 daysSchuth Alexander O.COO and SecretarySSale−2.54K$49.60−$126.2K−0.5%484.0K after2 lots
Aug 23, 2021 (view filing)Aug 194 daysHo CaroleChief Medical OfficerSSale−2.55K$49.58−$126.2K−1.5%164.8K after2 lots
Aug 25, 2021 (view filing)Aug 232 daysHo CaroleChief Medical OfficerSSale−6.14K$48.91−$300.5K−3.7%158.6K after
Sep 3, 2021 (view filing)Sep 12 daysWatts Ryan J.President and CEOSSale−18.3K$54.66−$1.00M−0.8%2.16M after2 lots
Sep 9, 2021 (view filing)Sep 72 daysSchuth Alexander O.COO and SecretarySSale−10.0K$55.55−$555.5K−2.1%474.0K after3 lots
Sep 17, 2021 (view filing)Sep 152 daysSato Vicki LDirectorSSale−1.67K$53.40−$89.0K−1.3%129.5K after4 lots
Oct 5, 2021 (view filing)Oct 14 daysWatts Ryan J.President and CEOSSale−18.3K$50.38−$923.6K−0.8%2.14M after3 lots
Oct 6, 2021 (view filing)Oct 42 daysSchuth Alexander O.COO and SecretarySSale−10.0K$50.56−$505.6K−2.1%473.1K after2 lots
Nov 3, 2021 (view filing)Nov 12 daysSato Vicki LDirectorSSale−1.67K$50.05−$83.4K−1.3%127.8K after
Nov 3, 2021 (view filing)Nov 12 daysWatts Ryan J.President and CEOSSale−18.3K$49.76−$912.2K−0.9%2.12M after2 lots
Nov 8, 2021 (view filing)Nov 44 daysSchuth Alexander O.COO and SecretarySSale−10.0K$52.84−$528.4K−2.1%463.1K after2 lots
Nov 12, 2021 (view filing)Nov 102 daysSato Vicki LDirectorSSale−1.67K$52.81−$88.0K−1.3%126.2K after2 lots
Dec 3, 2021 (view filing)Dec 12 daysWatts Ryan J.President and CEOSSale−18.3K$44.92−$823.6K−0.9%2.10M after3 lots
Dec 8, 2021 (view filing)Dec 62 daysHo CaroleChief Medical OfficerSSale−1.48K$42.52−$62.8K−1.9%76.3K after
Dec 8, 2021 (view filing)Dec 62 daysSchuth Alexander O.COO and SecretarySSale−10.0K$42.27−$422.7K−2.2%453.1K after2 lots
Dec 30, 2021 (view filing)Dec 28-302 daysTessier-Lavigne MarcDirectorSSale−63.1K$44.43−$2.81M−44.5%78.8K after12 lots
Jan 7, 2022 (view filing)Jan 52 daysSchuth Alexander O.COO and SecretarySSale−2.85K$44.77−$127.4K−0.6%457.7K after
Jan 7, 2022 (view filing)Jan 52 daysHo CaroleChief Medical OfficerSSale−2.85K$44.78−$127.4K−1.7%163.3K after
Jan 7, 2022 (view filing)Jan 52 daysKrognes Steve E.CFO and TreasurerSSale−2.23K$44.75−$99.6K−1.8%124.1K after
Jan 7, 2022 (view filing)Jan 52 daysWatts Ryan J.President and CEOSSale−5.01K$44.78−$224.2K−0.2%2.11M after
Feb 11, 2022 (view filing)Feb 92 daysHo CaroleChief Medical OfficerSSale−1.42K$37.10−$52.8K−0.8%166.1K after
Feb 11, 2022 (view filing)Feb 92 daysSchuth Alexander O.COO and SecretarySSale−1.42K$37.10−$52.8K−0.3%460.6K after
Feb 11, 2022 (view filing)Feb 92 daysWatts Ryan J.President and CEOSSale−2.72K$37.55−$102.1K−0.1%2.12M after
Feb 11, 2022 (view filing)Feb 92 daysKrognes Steve E.CFO and TreasurerSSale−1.30K$37.09−$48.1K−1.0%122.8K after
Feb 15, 2022 (view filing)Feb 114 daysHo CaroleChief Medical OfficerSSale−2.92K$34.71−$101.3K−1.7%170.7K after
Feb 15, 2022 (view filing)Feb 114 daysSchuth Alexander O.COO and SecretarySSale−2.80K$34.68−$97.2K−0.6%465.0K after
Feb 15, 2022 (view filing)Feb 114 daysKrognes Steve E.CFO and TreasurerSSale−2.56K$34.69−$88.8K−2.1%120.2K after
Feb 15, 2022 (view filing)Feb 114 daysWatts Ryan J.President and CEOSSale−9.49K$34.72−$329.5K−0.4%2.13M after
Jun 28, 2022 (view filing)Mar 2397 daysTessier-Lavigne MarcDirectorSSale−20.0K$33.83−$676.6K−1.0%2.02M afterAmended2 lots
Jul 27, 2022 (view filing)Jul 252 daysTessier-Lavigne MarcDirectorSSale−20.0K$35.61−$712.1K−1.0%1.95M after2 lots
Aug 23, 2022 (view filing)Aug 194 daysHo CaroleChief Medical OfficerSSale−2.58K$33.22−$85.6K−1.5%173.1K after
Aug 23, 2022 (view filing)Aug 194 daysSchuth Alexander O.COFO and SecretarySSale−2.58K$33.22−$85.6K−0.5%467.5K after
Aug 23, 2022 (view filing)Aug 194 daysKrognes Steve E.DirectorSSale−2.25K$33.22−$74.8K−1.5%149.5K after
Aug 23, 2022 (view filing)Aug 194 daysWatts Ryan J.President and CEOSSale−2.40K$33.22−$79.9K−0.1%2.20M after
Aug 25, 2022 (view filing)Aug 232 daysHo CaroleChief Medical OfficerSSale−2.42K$31.98−$77.5K−1.4%170.7K after
Aug 25, 2022 (view filing)Aug 232 daysTessier-Lavigne MarcDirectorSSale−20.0K$31.61−$632.3K−1.0%1.93M after2 lots
Sep 30, 2022 (view filing)Sep 282 daysTessier-Lavigne MarcDirectorSSale−20.0K$30.82−$616.3K−1.0%1.91M after2 lots
Nov 3, 2022 (view filing)Nov 1-22 daysTessier-Lavigne MarcDirectorSSale−20.0K$30.27−$605.5K−1.0%1.89M after2 lots
Nov 28, 2022 (view filing)Nov 235 daysTessier-Lavigne MarcDirectorSSale−20.0K$30.48−$609.6K−1.1%1.87M after
Jan 5, 2023 (view filing)Jan 41 dayWatts Ryan J.President and CEOSSale−5.03K$28.73−$144.5K−0.2%2.21M after
Jan 5, 2023 (view filing)Jan 41 dayHo CaroleChief Medical OfficerSSale−2.91K$28.69−$83.6K−1.6%175.5K after
Jan 9, 2023 (view filing)Jan 45 daysSchuth Alexander O.COFO and SecretarySSale−2.91K$28.70−$83.6K−0.6%492.3K afterAmended