Cytokinetics Inc
CYTK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001061983
In the last 90 days, Cytokinetics Inc insiders filed 0 open-market purchases and 16 sales; 482 institutions reported holding it in 13F filings for Q2 2026, worth $13.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Cytokinetics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 431
- +58 vs. Q3 2025
- Shares held
- 139.5M
- −1.24M (−0.9%) vs. Q3 2025
- Total value
- $8.87B
- +$1.13B (+14.6%) vs. Q3 2025
- New holders
- 106
- 143 more added
- Sold out
- 48
- 134 more reduced
8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CYTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 482 | $13.7B |
| Q1 2026 | 441 | $9.63B |
| Q4 2025 | 431 | $8.87B |
| Q3 2025 | 381 | $7.75B |
| Q2 2025 | 312 | $4.55B |
| Q1 2025 | 356 | $5.48B |
| Q4 2024 | 347 | $6.18B |
| Q3 2024 | 348 | $7.20B |
| Q2 2024 | 344 | $7.34B |
| Q1 2024 | 390 | $8.26B |
| Q4 2023 | 347 | $9.54B |
| Q3 2023 | 251 | $3.22B |
| Q2 2023 | 253 | $3.55B |
| Q1 2023 | 263 | $3.83B |
| Q4 2022 | 278 | $4.88B |
| Q3 2022 | 276 | $5.08B |
| Q2 2022 | 263 | $4.16B |
| Q1 2022 | 240 | $3.52B |
| Q4 2021 | 250 | $4.16B |
| Q3 2021 | 211 | $3.22B |
| Q2 2021 | 191 | $1.50B |
| Q1 2021 | 193 | $1.74B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Cytokinetics Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nomura Holdings Inc | 66,207 | $4.21M | 0.01% | −41,046−38.3% | Reduced |
| Great West Life Assurance Co | 66,203 | $4.21M | 0.01% | −12,341−15.7% | Reduced |
| State of Wisconsin Investment Board | 68,633 | $4.36M | 0.01% | −6,292−8.4% | Reduced |
| SEI Investments Co | 70,239 | $4.46M | 0.00% | +1,467+2.1% | Added |
| Nicholas Investment Partners, LP | 70,240 | $4.46M | 0.33% | +8,123+13.1% | Added |
| DekaBank Deutsche Girozentrale | 57,500 | $4.46M | 0.01% | 00.0% | Unchanged |
| Neuberger Berman Group LLC | 71,378 | $4.54M | 0.00% | +65,069+1,031.4% | Added |
| Lisanti Capital Growth, LLC | 74,200 | $4.71M | 1.12% | +25,130+51.2% | Added |
| Erste Asset Management GmbH | 76,950 | $4.75M | 0.04% | 00.0% | Unchanged |
| Monashee Investment Management LLC | 75,000 | $4.77M | 2.69% | −25,000−25.0% | Reduced |
| Moody Aldrich Partners LLC | 78,618 | $5.00M | 0.93% | −3,842−4.7% | Reduced |
| Granahan Investment Management Inc | 82,121 | $5.22M | 0.22% | +28,571+53.4% | Added |
| Raymond James Financial Inc | 82,395 | $5.24M | 0.00% | +40,187+95.2% | Added |
| Thornburg Investment Management Inc | 82,398 | $5.24M | 0.07% | −2,321−2.7% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 88,684 | $5.64M | 0.02% | −61,273−40.9% | Reduced |
| XTX Topco Ltd | 90,579 | $5.76M | 0.15% | +86,589+2,170.2% | Added |
| Sphera Funds Management Ltd. | 91,717 | $5.83M | 1.22% | −69,800−43.2% | Reduced |
| Mutual of America Capital Management LLC | 95,230 | $6.05M | 0.06% | +39,969+72.3% | Added |
| Campbell & CO Investment Adviser LLC | 96,484 | $6.13M | 0.29% | +96,484 | New |
| Creative Planning | 96,939 | $6.16M | 0.00% | +9,629+11.0% | Added |
| Aquatic Capital Management LLC | 97,497 | $6.19M | 0.18% | −38,372−28.2% | Reduced |
| Rafferty Asset Management, LLC | 98,541 | $6.26M | 0.02% | −5,567−5.3% | Reduced |
| Deeter Investments LLP | 98,739 | $6.27M | 1.35% | +98,739 | New |
| Boxer Capital Management, LLC | 100,000 | $6.35M | 1.39% | −100,000−50.0% | Reduced |
| Impax Asset Management Group plc | 100,000 | $6.35M | 0.04% | −75,000−42.9% | Reduced |
| Brevan Howard Capital Management LP | 101,030 | $6.42M | 0.12% | +91,056+912.9% | Added |
| Citigroup Inc | 102,101 | $6.49M | 0.00% | +37,203+57.3% | Added |
| California State Teachers Retirement System | 107,324 | $6.82M | 0.01% | −124−0.1% | Reduced |
| Peregrine Capital Management LLC | 108,062 | $6.87M | 0.21% | −46,387−30.0% | Reduced |
| Engineers Gate Manager LP | 111,544 | $7.09M | 0.08% | +111,544 | New |
| New York State Teachers Retirement System | 114,500 | $7.28M | 0.01% | 00.0% | Unchanged |
| HighVista Strategies LLC | 114,564 | $7.28M | 1.87% | −18,366−13.8% | Reduced |
| D. E. Shaw & Co., Inc. | 119,221 | $7.58M | 0.01% | +105,618+776.4% | Added |
| MetLife Investment Management | 121,910 | $7.75M | 0.04% | −5,680−4.5% | Reduced |
| Readystate Asset Management LP | 122,711 | $7.80M | 0.34% | −19,771−13.9% | Reduced |
| Exome Asset Management LLC | 124,749 | $7.93M | 3.92% | −17,668−12.4% | Reduced |
| First Trust Advisors LP | 127,524 | $8.10M | 0.01% | +127,524 | New |
| Hood River Capital Management LLC | 137,597 | $8.74M | 0.10% | +137,597 | New |
| Russell Investments Group, Ltd. | 137,690 | $8.75M | 0.01% | +17,800+14.8% | Added |
| Royce & Associates LP | 144,426 | $9.18M | 0.09% | +44,343+44.3% | Added |
| Candriam Luxembourg S.C.A. | 146,631 | $9.32M | 0.05% | +146,631 | New |
| Retirement Systems of Alabama | 146,668 | $9.32M | 0.03% | +1,996+1.4% | Added |
| StemPoint Capital LP | 146,978 | $9.34M | 1.60% | +146,978 | New |
| Wells Fargo & Company | 161,556 | $10.3M | 0.00% | +64,096+65.8% | Added |
| Checkpoint Capital L.P. | 166,823 | $10.6M | 3.36% | +129,236+343.8% | Added |
| Legal & General Group Plc | 168,586 | $10.7M | 0.00% | −11,064−6.2% | Reduced |
| Renaissance Technologies LLC | 172,067 | $10.9M | 0.02% | −117,900−40.7% | Reduced |
| Ikarian Capital, LLC | 172,672 | $11.0M | 1.42% | −50,002−22.5% | Reduced |
| Two Sigma Advisers, LP | 174,700 | $11.1M | 0.02% | +174,700 | New |
| Hudson Bay Capital Management LP | 175,350 | $11.1M | 0.06% | −6,781−3.7% | Reduced |
| Deutsche Bank AG | 175,804 | $11.2M | 0.00% | +10,240+6.2% | Added |
| Manufacturers Life Insurance Company, The | 190,807 | $12.0M | 0.01% | −1,090−0.6% | Reduced |
| California Public Employees Retirement System | 189,401 | $12.0M | 0.01% | +39,002+25.9% | Added |
| Segall Bryant & Hamill, LLC | 189,513 | $12.0M | 0.16% | +8,463+4.7% | Added |
| Pinnacle Associates Ltd | 190,999 | $12.1M | 0.16% | −10,491−5.2% | Reduced |
| Rosalind Advisors, Inc. | 195,045 | $12.4M | 4.75% | −204,955−51.2% | Reduced |
| Mirador Capital Partners LP | 198,558 | $12.6M | 1.73% | +1,191+0.6% | Added |
| Invesco Ltd. | 204,878 | $13.0M | 0.00% | +47,629+30.3% | Added |
| Handelsbanken Fonder AB | 205,800 | $13.1M | 0.04% | −28,700−12.2% | Reduced |
| Swiss National Bank | 224,200 | $14.2M | 0.01% | +4,300+2.0% | Added |
| Millennium Management LLC | 225,456 | $14.3M | 0.01% | −117,077−34.2% | Reduced |
| AQR Capital Management LLC | 236,925 | $14.8M | 0.01% | −276,365−53.8% | Reduced |
| UBS Asset Management Americas Inc | 235,049 | $14.9M | 0.00% | −3,333−1.4% | Reduced |
| Janus Henderson Group PLC | 256,212 | $16.3M | 0.01% | +206,648+416.9% | Added |
| Catalio Capital Management, LP | 258,381 | $16.4M | 2.90% | −193,200−42.8% | Reduced |
| Two Sigma Investments, LP | 274,017 | $17.4M | 0.03% | +274,017 | New |
| Susquehanna Portfolio Strategies, LLC | 278,429 | $17.7M | 0.27% | 00.0% | Unchanged |
| Jane Street Group, LLC | 284,125 | $18.1M | 0.02% | +284,125 | New |
| Logos Global Management LP | 300,000 | $19.1M | 1.27% | +300,000 | New |
| First Turn Management, LLC | 325,668 | $20.7M | 2.36% | +70,873+27.8% | Added |
| Massachusetts Financial Services Co | 327,202 | $20.8M | 0.01% | −169,471−34.1% | Reduced |
| Marshall Wace, LLP | 337,031 | $21.4M | 0.02% | +158,051+88.3% | Added |
| GSK plc | 340,434 | $21.6M | 2.71% | +340,434 | New |
| ExodusPoint Capital Management, LP | 343,144 | $21.8M | 0.24% | +343,144 | New |
| Barclays PLC | 343,458 | $21.8M | 0.01% | −54,617−13.7% | Reduced |
| Rhumbline Advisers | 356,995 | $22.7M | 0.02% | −28,818−7.5% | Reduced |
| E. Ohman J:or Asset Management AB | 362,962 | $23.1M | 0.54% | −44,075−10.8% | Reduced |
| Nuveen, LLC | 369,279 | $23.5M | 0.01% | −1,636−0.4% | Reduced |
| DAFNA Capital Management LLC | 370,997 | $23.6M | 5.48% | −23,943−6.1% | Reduced |
| Gilder Gagnon Howe & Co LLC | 385,820 | $24.5M | 0.26% | −3,235−0.8% | Reduced |
| Sarissa Capital Management LP | 396,357 | $25.2M | 11.30% | −192,000−32.6% | Reduced |
| Group One Trading, L.P. | 407,253 | $25.9M | 0.77% | +219,284+116.7% | Added |
| Franklin Resources Inc | 409,990 | $26.1M | 0.01% | +265+0.1% | Added |
| Alliancebernstein L.P. | 412,966 | $26.2M | 0.01% | +177,550+75.4% | Added |
| American Century Companies Inc | 443,910 | $28.2M | 0.01% | +14,707+3.4% | Added |
| Foresite Capital Management IV, LLC | 458,295 | $29.1M | 12.68% | 00.0% | Unchanged |
| GW&K Investment Management, LLC | 472,363 | $30.0M | 0.26% | +291,693+161.5% | Added |
| Eventide Asset Management, LLC | 479,611 | $30.5M | 0.48% | +309,503+181.9% | Added |
| Standard Life Aberdeen plc | 483,061 | $30.7M | 0.05% | −444,771−47.9% | Reduced |
| Federated Hermes, Inc. | 483,668 | $30.7M | 0.05% | +457,874+1,775.1% | Added |
| Qube Research & Technologies Ltd | 537,277 | $34.1M | 0.05% | +528,239+5,844.6% | Added |
| ADAR1 Capital Management, LLC | 540,166 | $34.3M | 2.57% | +21,245+4.1% | Added |
| TD Asset Management Inc | 544,010 | $34.6M | 0.03% | −127,770−19.0% | Reduced |
| Ameriprise Financial Inc | 545,805 | $34.7M | 0.01% | −18,742−3.3% | Reduced |
| BNP Paribas Arbitrage, SA | 579,862 | $36.8M | 0.02% | +332,397+134.3% | Added |
| Melqart Asset Management (UK) Ltd | 622,898 | $39.6M | 3.96% | −160,876−20.5% | Reduced |
| Brown Advisory Inc | 731,154 | $46.5M | 0.06% | −181,032−19.8% | Reduced |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 747,983 | $47.5M | 4.22% | −444,501−37.3% | Reduced |
| Susquehanna International Group, LLP | 753,617 | $47.9M | 0.07% | −264,184−26.0% | Reduced |
| Pictet Asset Management Holding SA | 757,563 | $48.0M | 0.05% | −387,995−33.9% | Reduced |