Cytokinetics Inc
CYTK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001061983
In the last 90 days, Cytokinetics Inc insiders filed 0 open-market purchases and 18 sales; 481 institutions reported holding it in 13F filings for Q2 2026, worth $13.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Cytokinetics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 431
- +58 vs. Q3 2025
- Shares held
- 139.5M
- −1.24M (−0.9%) vs. Q3 2025
- Total value
- $8.87B
- +$1.13B (+14.6%) vs. Q3 2025
- New holders
- 106
- 143 more added
- Sold out
- 48
- 134 more reduced
8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CYTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 481 | $13.7B |
| Q1 2026 | 441 | $9.63B |
| Q4 2025 | 431 | $8.87B |
| Q3 2025 | 381 | $7.75B |
| Q2 2025 | 312 | $4.55B |
| Q1 2025 | 356 | $5.48B |
| Q4 2024 | 347 | $6.18B |
| Q3 2024 | 348 | $7.20B |
| Q2 2024 | 344 | $7.34B |
| Q1 2024 | 390 | $8.26B |
| Q4 2023 | 347 | $9.54B |
| Q3 2023 | 251 | $3.22B |
| Q2 2023 | 253 | $3.55B |
| Q1 2023 | 263 | $3.83B |
| Q4 2022 | 278 | $4.88B |
| Q3 2022 | 276 | $5.08B |
| Q2 2022 | 263 | $4.16B |
| Q1 2022 | 240 | $3.52B |
| Q4 2021 | 250 | $4.16B |
| Q3 2021 | 211 | $3.22B |
| Q2 2021 | 191 | $1.50B |
| Q1 2021 | 193 | $1.74B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Cytokinetics Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| T. Rowe Price Investment Management, Inc. | 17,716,372 | $1.13B | 0.71% | −1,364,124−7.1% | Reduced |
| BlackRock, Inc. | 16,395,123 | $1.04B | 0.02% | +869,376+5.6% | Added |
| FMR LLC | 12,807,752 | $813.8M | 0.04% | −283,895−2.2% | Reduced |
| Vanguard Group Inc | 12,048,131 | $765.5M | 0.01% | +191,336+1.6% | Added |
| Wellington Management Group LLP | 7,937,063 | $504.3M | 0.09% | +528,502+7.1% | Added |
| State Street Corp | 5,825,295 | $370.1M | 0.01% | +207,961+3.7% | Added |
| Deep Track Capital, LP | 3,336,998 | $212.0M | 4.84% | −963,002−22.4% | Reduced |
| Geode Capital Management, LLC | 3,056,017 | $194.2M | 0.01% | +15,815+0.5% | Added |
| Bank of America Corp | 2,941,152 | $186.9M | 0.01% | −120,644−3.9% | Reduced |
| RTW Investments, LP | 2,721,158 | $172.9M | 1.73% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 2,422,612 | $153.9M | 0.70% | −360,318−12.9% | Reduced |
| Goldman Sachs Group Inc | 2,371,679 | $150.7M | 0.02% | +736,956+45.1% | Added |
| Price T Rowe Associates Inc | 1,930,119 | $122.6M | 0.01% | −436,729−18.5% | Reduced |
| Woodline Partners LP | 1,648,428 | $104.7M | 0.41% | +7030.0% | Added |
| JPMorgan Chase & Co | 1,412,797 | $89.8M | 0.01% | −130,060−8.4% | Reduced |
| Integral Health Asset Management, LLC | 1,400,000 | $89.0M | 4.51% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 1,383,437 | $87.9M | 0.01% | +9,554+0.7% | Added |
| Northern Trust Corp | 1,380,787 | $87.7M | 0.01% | −26,045−1.9% | Reduced |
| Morgan Stanley | 1,265,301 | $80.4M | 0.00% | −255,885−16.8% | Reduced |
| Capital International Investors | 1,178,780 | $74.9M | 0.01% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,162,937 | $73.9M | 0.05% | −223,128−16.1% | Reduced |
| UBS Group AG | 1,131,456 | $71.9M | 0.01% | −671,795−37.3% | Reduced |
| Armistice Capital, LLC | 992,766 | $63.1M | 1.54% | −204,102−17.1% | Reduced |
| Royalty Pharma Sub-Manager, LLC | 980,392 | $62.3M | 36.36% | +980,392 | New |
| Principal Financial Group Inc | 976,892 | $62.1M | 0.03% | −197,556−16.8% | Reduced |
| Frazier Life Sciences Management, L.P. | 934,642 | $59.4M | 1.60% | +44,197+5.0% | Added |
| Bank of New York Mellon Corp | 854,309 | $54.3M | 0.01% | −14,922−1.7% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 827,863 | $52.6M | 0.06% | +42,863+5.5% | Added |
| Fisher Asset Management, LLC | 822,885 | $52.3M | 0.02% | +61,298+8.0% | Added |
| Norges Bank | 807,070 | $51.3M | 0.01% | +807,070 | New |
| Affinity Asset Advisors, LLC | 800,000 | $50.8M | 3.65% | +450,000+128.6% | Added |
| Pictet Asset Management Holding SA | 757,563 | $48.0M | 0.05% | −387,995−33.9% | Reduced |
| Susquehanna International Group, LLP | 753,617 | $47.9M | 0.07% | −264,184−26.0% | Reduced |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 747,983 | $47.5M | 4.22% | −444,501−37.3% | Reduced |
| Brown Advisory Inc | 731,154 | $46.5M | 0.06% | −181,032−19.8% | Reduced |
| Melqart Asset Management (UK) Ltd | 622,898 | $39.6M | 3.96% | −160,876−20.5% | Reduced |
| BNP Paribas Arbitrage, SA | 579,862 | $36.8M | 0.02% | +332,397+134.3% | Added |
| Ameriprise Financial Inc | 545,805 | $34.7M | 0.01% | −18,742−3.3% | Reduced |
| TD Asset Management Inc | 544,010 | $34.6M | 0.03% | −127,770−19.0% | Reduced |
| ADAR1 Capital Management, LLC | 540,166 | $34.3M | 2.57% | +21,245+4.1% | Added |
| Qube Research & Technologies Ltd | 537,277 | $34.1M | 0.05% | +528,239+5,844.6% | Added |
| Federated Hermes, Inc. | 483,668 | $30.7M | 0.05% | +457,874+1,775.1% | Added |
| Standard Life Aberdeen plc | 483,061 | $30.7M | 0.05% | −444,771−47.9% | Reduced |
| Eventide Asset Management, LLC | 479,611 | $30.5M | 0.48% | +309,503+181.9% | Added |
| GW&K Investment Management, LLC | 472,363 | $30.0M | 0.26% | +291,693+161.5% | Added |
| Foresite Capital Management IV, LLC | 458,295 | $29.1M | 12.68% | 00.0% | Unchanged |
| American Century Companies Inc | 443,910 | $28.2M | 0.01% | +14,707+3.4% | Added |
| Alliancebernstein L.P. | 412,966 | $26.2M | 0.01% | +177,550+75.4% | Added |
| Franklin Resources Inc | 409,990 | $26.1M | 0.01% | +265+0.1% | Added |
| Group One Trading, L.P. | 407,253 | $25.9M | 0.77% | +219,284+116.7% | Added |
| Sarissa Capital Management LP | 396,357 | $25.2M | 11.30% | −192,000−32.6% | Reduced |
| Gilder Gagnon Howe & Co LLC | 385,820 | $24.5M | 0.26% | −3,235−0.8% | Reduced |
| DAFNA Capital Management LLC | 370,997 | $23.6M | 5.48% | −23,943−6.1% | Reduced |
| Nuveen, LLC | 369,279 | $23.5M | 0.01% | −1,636−0.4% | Reduced |
| E. Ohman J:or Asset Management AB | 362,962 | $23.1M | 0.54% | −44,075−10.8% | Reduced |
| Rhumbline Advisers | 356,995 | $22.7M | 0.02% | −28,818−7.5% | Reduced |
| Barclays PLC | 343,458 | $21.8M | 0.01% | −54,617−13.7% | Reduced |
| ExodusPoint Capital Management, LP | 343,144 | $21.8M | 0.24% | +343,144 | New |
| GSK plc | 340,434 | $21.6M | 2.71% | +340,434 | New |
| Marshall Wace, LLP | 337,031 | $21.4M | 0.02% | +158,051+88.3% | Added |
| Massachusetts Financial Services Co | 327,202 | $20.8M | 0.01% | −169,471−34.1% | Reduced |
| First Turn Management, LLC | 325,668 | $20.7M | 2.36% | +70,873+27.8% | Added |
| Logos Global Management LP | 300,000 | $19.1M | 1.27% | +300,000 | New |
| Jane Street Group, LLC | 284,125 | $18.1M | 0.02% | +284,125 | New |
| Susquehanna Portfolio Strategies, LLC | 278,429 | $17.7M | 0.27% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 274,017 | $17.4M | 0.03% | +274,017 | New |
| Catalio Capital Management, LP | 258,381 | $16.4M | 2.90% | −193,200−42.8% | Reduced |
| Janus Henderson Group PLC | 256,212 | $16.3M | 0.01% | +206,648+416.9% | Added |
| UBS Asset Management Americas Inc | 235,049 | $14.9M | 0.00% | −3,333−1.4% | Reduced |
| AQR Capital Management LLC | 236,925 | $14.8M | 0.01% | −276,365−53.8% | Reduced |
| Millennium Management LLC | 225,456 | $14.3M | 0.01% | −117,077−34.2% | Reduced |
| Swiss National Bank | 224,200 | $14.2M | 0.01% | +4,300+2.0% | Added |
| Handelsbanken Fonder AB | 205,800 | $13.1M | 0.04% | −28,700−12.2% | Reduced |
| Invesco Ltd. | 204,878 | $13.0M | 0.00% | +47,629+30.3% | Added |
| Mirador Capital Partners LP | 198,558 | $12.6M | 1.73% | +1,191+0.6% | Added |
| Rosalind Advisors, Inc. | 195,045 | $12.4M | 4.75% | −204,955−51.2% | Reduced |
| Pinnacle Associates Ltd | 190,999 | $12.1M | 0.16% | −10,491−5.2% | Reduced |
| Segall Bryant & Hamill, LLC | 189,513 | $12.0M | 0.16% | +8,463+4.7% | Added |
| California Public Employees Retirement System | 189,401 | $12.0M | 0.01% | +39,002+25.9% | Added |
| Manufacturers Life Insurance Company, The | 190,807 | $12.0M | 0.01% | −1,090−0.6% | Reduced |
| Deutsche Bank AG | 175,804 | $11.2M | 0.00% | +10,240+6.2% | Added |
| Hudson Bay Capital Management LP | 175,350 | $11.1M | 0.06% | −6,781−3.7% | Reduced |
| Two Sigma Advisers, LP | 174,700 | $11.1M | 0.02% | +174,700 | New |
| Ikarian Capital, LLC | 172,672 | $11.0M | 1.42% | −50,002−22.5% | Reduced |
| Renaissance Technologies LLC | 172,067 | $10.9M | 0.02% | −117,900−40.7% | Reduced |
| Legal & General Group Plc | 168,586 | $10.7M | 0.00% | −11,064−6.2% | Reduced |
| Checkpoint Capital L.P. | 166,823 | $10.6M | 3.36% | +129,236+343.8% | Added |
| Wells Fargo & Company | 161,556 | $10.3M | 0.00% | +64,096+65.8% | Added |
| StemPoint Capital LP | 146,978 | $9.34M | 1.60% | +146,978 | New |
| Retirement Systems of Alabama | 146,668 | $9.32M | 0.03% | +1,996+1.4% | Added |
| Candriam Luxembourg S.C.A. | 146,631 | $9.32M | 0.05% | +146,631 | New |
| Royce & Associates LP | 144,426 | $9.18M | 0.09% | +44,343+44.3% | Added |
| Russell Investments Group, Ltd. | 137,690 | $8.75M | 0.01% | +17,800+14.8% | Added |
| Hood River Capital Management LLC | 137,597 | $8.74M | 0.10% | +137,597 | New |
| First Trust Advisors LP | 127,524 | $8.10M | 0.01% | +127,524 | New |
| Exome Asset Management LLC | 124,749 | $7.93M | 3.92% | −17,668−12.4% | Reduced |
| Readystate Asset Management LP | 122,711 | $7.80M | 0.34% | −19,771−13.9% | Reduced |
| MetLife Investment Management | 121,910 | $7.75M | 0.04% | −5,680−4.5% | Reduced |
| D. E. Shaw & Co., Inc. | 119,221 | $7.58M | 0.01% | +105,618+776.4% | Added |
| HighVista Strategies LLC | 114,564 | $7.28M | 1.87% | −18,366−13.8% | Reduced |