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CRISPR Therapeutics AG

CRSP
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001674416

In the last 90 days, CRISPR Therapeutics AG insiders filed 0 open-market purchases and 2 sales; 525 institutions reported holding it in 13F filings for Q2 2026, worth $4.16B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in CRISPR Therapeutics AG as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
482
+44 vs. Q3 2025
Shares held
76.5M
+4.26M (+5.9%) vs. Q3 2025
Total value
$4.01B
−$669.3M (−14.3%) vs. Q3 2025
New holders
96
149 more added
Sold out
52
129 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRSP on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 482 institutions
Q1 2021: 446 institutionsQ2 2021: 501 institutionsQ3 2021: 477 institutionsQ4 2021: 448 institutionsQ1 2022: 446 institutionsQ2 2022: 437 institutionsQ3 2022: 436 institutionsQ4 2022: 399 institutionsQ1 2023: 383 institutionsQ2 2023: 420 institutionsQ3 2023: 410 institutionsQ4 2023: 472 institutionsQ1 2024: 483 institutionsQ2 2024: 450 institutionsQ3 2024: 417 institutionsQ4 2024: 406 institutionsQ1 2025: 398 institutionsQ2 2025: 435 institutionsQ3 2025: 442 institutionsQ4 2025: 482 institutionsQ1 2026: 494 institutionsQ2 2026: 525 institutions
Value heldQ4 2025: $4.01B
Q1 2021: $5.20BQ2 2021: $6.57BQ3 2021: $4.53BQ4 2021: $3.25BQ1 2022: $3.10BQ2 2022: $3.35BQ3 2022: $3.70BQ4 2022: $2.26BQ1 2023: $2.54BQ2 2023: $3.07BQ3 2023: $2.50BQ4 2023: $3.48BQ1 2024: $4.10BQ2 2024: $3.22BQ3 2024: $2.81BQ4 2024: $2.54BQ1 2025: $2.20BQ2 2025: $3.52BQ3 2025: $4.68BQ4 2025: $4.01BQ1 2026: $3.67BQ2 2026: $4.16B
Institutions holding CRSP and their total value by quarter
QuarterHoldersValue
Q2 2026525$4.16B
Q1 2026494$3.67B
Q4 2025482$4.01B
Q3 2025442$4.68B
Q2 2025435$3.52B
Q1 2025398$2.20B
Q4 2024406$2.54B
Q3 2024417$2.81B
Q2 2024450$3.22B
Q1 2024483$4.10B
Q4 2023472$3.48B
Q3 2023410$2.50B
Q2 2023420$3.07B
Q1 2023383$2.54B
Q4 2022399$2.26B
Q3 2022436$3.70B
Q2 2022437$3.35B
Q1 2022446$3.10B
Q4 2021448$3.25B
Q3 2021477$4.53B
Q2 2021501$6.57B
Q1 2021446$5.20B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding CRISPR Therapeutics AG; share changes are against Q3 2025.

Institutions holding CRSP in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Envestnet Asset Management Inc56,572$2.97M0.00%−13,817−19.6%Reduced
Guggenheim Capital LLC57,021$2.99M0.02%−440−0.8%Reduced
EverSource Wealth Advisors, LLC57,465$3.01M0.11%−39,969−41.0%Reduced
Jones Financial Companies LLLP57,489$3.01M0.00%+12,774+28.6%Added
Advisor Group Holdings, Inc.59,211$3.10M0.00%+3,276+5.9%Added
Invesco Ltd.60,796$3.19M0.00%−4,531−6.9%Reduced
Congress Asset Management Co63,336$3.32M0.02%−4,774−7.0%Reduced
Cetera Investment Advisers63,913$3.35M0.00%+83+0.1%Added
Nwam LLC61,843$3.38M0.19%−39,926−39.2%Reduced
Deutsche Bank AG70,492$3.70M0.00%+5,690+8.8%Added
Slow Capital, Inc.76,630$4.02M0.48%+3,343+4.6%Added
Commonwealth Equity Services, LLC78,113$4.10M0.01%+9,016+13.0%Added
California State Teachers Retirement System78,123$4.10M0.00%+3,212+4.3%Added
Neo Ivy Capital Management78,726$4.13M0.65%+78,726New
Himension Fund84,390$4.43M0.27%+12,051+16.7%Added
Price T Rowe Associates Inc84,940$4.46M0.00%+8,405+11.0%Added
Van Eck Associates Corp85,831$4.50M0.00%+2,187+2.6%Added
Legal & General Group Plc87,911$4.61M0.00%−4,568−4.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.89,708$4.71M0.01%−9,496−9.6%Reduced
Group One Trading, L.P.93,954$4.93M0.15%−3,288−3.4%Reduced
Baker Chad R93,270$4.96M0.89%+65+0.1%Added
Capital International Sarl94,769$4.97M0.08%−4,888−4.9%Reduced
Alliancebernstein L.P.96,357$5.05M0.00%+10,023+11.6%Added
Beck Bode, LLC98,801$5.18M0.86%+98,801New
Wealth Enhancement Advisory Services, LLC89,356$5.20M0.01%+5,340+6.4%Added
Rafferty Asset Management, LLC101,014$5.30M0.02%−53,281−34.5%Reduced
Algert Global LLC102,850$5.39M0.08%+102,850New
Private Advisor Group, LLC107,259$5.62M0.03%−10,854−9.2%Reduced
Rockefeller Capital Management L.P.112,667$5.91M0.01%−35,864−24.1%Reduced
California Public Employees Retirement System116,104$6.09M0.00%+6,732+6.2%Added
Reynders McVeigh Capital Management, LLC116,514$6.11M0.29%+3,514+3.1%Added
Rhumbline Advisers118,778$6.23M0.01%−5,129−4.1%Reduced
No Street GP LP125,000$6.55M0.44%+125,000New
Marex Group plc127,546$6.69M0.07%+3,777+3.1%Added
Citigroup Inc132,693$6.96M0.00%+72,204+119.4%Added
Versant Venture Management, LLC148,831$7.80M5.17%00.0%Unchanged
UBS Asset Management Americas Inc148,901$7.81M0.00%+148,901New
Contrarius Group Holdings Ltd156,605$8.21M0.40%−113,745−42.1%Reduced
TD Asset Management Inc158,416$8.31M0.01%−16,200−9.3%Reduced
Swiss National Bank161,500$8.47M0.01%+2,400+1.5%Added
Two Sigma Advisers, LP162,400$8.52M0.02%−410,572−71.7%Reduced
Royal Bank of Canada165,565$8.68M0.00%−300,605−64.5%Reduced
Raymond James Financial Inc167,148$8.77M0.00%+57,318+52.2%Added
LPL Financial LLC170,831$8.96M0.00%−40,230−19.1%Reduced
Pictet Asset Management Holding SA167,464$9.02M0.01%−25,129−13.0%Reduced
Nuveen, LLC183,384$9.62M0.00%+543+0.3%Added
Vestmark Advisory Solutions, Inc.249,548$13.1M0.18%+10,586+4.4%Added
Barclays PLC249,988$13.1M0.01%−99,863−28.5%Reduced
Citadel Advisors LLC267,685$14.0M0.01%+100,584+60.2%Added
Goldman Sachs Group Inc275,632$14.5M0.00%+42,090+18.0%Added
Ameriprise Financial Inc297,244$15.6M0.00%−14,619−4.7%Reduced
Bank of New York Mellon Corp310,954$16.3M0.00%+6,347+2.1%Added
Wells Fargo & Company318,878$16.7M0.00%+15,700+5.2%Added
Davy Global Fund Management Ltd389,519$20.4M1.41%+106,408+37.6%Added
Two Sigma Investments, LP470,621$24.7M0.04%−574,068−55.0%Reduced
Norges Bank490,206$25.7M0.00%+490,206New
JPMorgan Chase & Co542,954$28.5M0.00%−50,462−8.5%Reduced
Squarepoint Ops LLC581,108$30.5M0.06%+581,108New
Morgan Stanley667,060$35.0M0.00%−730,799−52.3%Reduced
Northern Trust Corp755,105$39.6M0.01%−24,825−3.2%Reduced
Susquehanna International Group, LLP853,971$44.8M0.06%+39,647+4.9%Added
Loomis Sayles & Co L P899,331$47.2M0.06%−10,383−1.1%Reduced
Dimensional Fund Advisors LP907,107$47.6M0.01%+30,078+3.4%Added
Charles Schwab Investment Management Inc1,030,182$54.0M0.01%+44,412+4.5%Added
NEA Management Company, LLC1,058,570$55.5M2.83%00.0%Unchanged
Bank of America Corp1,096,887$57.5M0.00%−27,232−2.4%Reduced
EcoR1 Capital, LLC1,389,276$72.9M3.34%00.0%Unchanged
FMR LLC1,953,957$102.5M0.01%+68,294+3.6%Added
Nikko Asset Management Americas, Inc.1,958,111$102.6M1.19%−205,564−9.5%Reduced
Sumitomo Mitsui Trust Holdings, Inc.1,958,111$102.7M0.06%−205,564−9.5%Reduced
Sr One Capital Management, LP2,038,763$106.9M15.14%00.0%Unchanged
Geode Capital Management, LLC2,249,223$118.0M0.01%+108,053+5.0%Added
Vanguard Group Inc2,268,394$119.0M0.00%−96,251−4.1%Reduced
UBS Group AG2,524,144$132.4M0.03%+185,088+7.9%Added
GSK plc3,220,627$168.9M21.14%+3,220,627New
T. Rowe Price Investment Management, Inc.3,226,595$169.2M0.11%−55,989−1.7%Reduced
State Street Corp3,753,440$196.8M0.01%−253,793−6.3%Reduced
Capital International Investors5,892,745$309.0M0.05%+243,487+4.3%Added
Orbis Allan Gray Ltd5,950,145$312.0M1.31%+968,060+19.4%Added
BlackRock, Inc.7,508,178$393.7M0.01%+458,033+6.5%Added
ARK Investment Management LLCSuperinvestorARK Invest10,522,057$551.8M3.66%+735,084+7.5%Added
Murphy, Middleton, Hinkle & Parker, Inc.906––+906New
O'Neil Global Advisors, Inc.0$00.00%−168,715−100.0%Sold out
Woodline Partners LP0$00.00%−143,575−100.0%Sold out
Nordea Investment Management AB0$00.00%−131,300−100.0%Sold out
Tang Capital Management LLC0$00.00%−100,000−100.0%Sold out
Del-Sette Capital Management, LLC0$00.00%−62,494−100.0%Sold out
Pathway Capital Management, LP0$00.00%−50,049−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−32,388−100.0%Sold out
GTS Securities LLC0$00.00%−20,696−100.0%Sold out
Scotia Capital Inc.0$00.00%−15,234−100.0%Sold out
Arete Wealth Advisors, LLC0$00.00%−7,370−100.0%Sold out
Sig Brokerage, LP0$00.00%−6,589−100.0%Sold out
Advyzon Investment Management, LLC0$00.00%−5,869−100.0%Sold out
Principal Financial Group Inc0$00.00%−5,771−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−5,534−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−4,955−100.0%Sold out
Cerity Partners LLC0$00.00%−4,188−100.0%Sold out
HC Advisors, LLC0$00.00%−3,913−100.0%Sold out
Swiss Life Asset Management Ltd0$00.00%−3,761−100.0%Sold out