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Climb Bio, Inc.

CLYM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001768446

In the last 90 days, Climb Bio, Inc. insiders filed 0 open-market purchases and 2 sales; 108 institutions reported holding it in 13F filings for Q2 2026, worth $734.3M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Climb Bio, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
65
−1 vs. Q3 2025
Shares held
31.2M
−13.4M (−30.0%) vs. Q3 2025
Total value
$157.4M
+$67.8M (+75.7%) vs. Q3 2025
New holders
17
21 more added
Sold out
18
21 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CLYM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 65 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 32 institutionsQ4 2021: 35 institutionsQ1 2022: 43 institutionsQ2 2022: 29 institutionsQ3 2022: 22 institutionsQ4 2022: 20 institutionsQ1 2023: 19 institutionsQ2 2023: 22 institutionsQ3 2023: 23 institutionsQ4 2023: 23 institutionsQ1 2024: 21 institutionsQ2 2024: 47 institutionsQ3 2024: 71 institutionsQ4 2024: 80 institutionsQ1 2025: 76 institutionsQ2 2025: 69 institutionsQ3 2025: 68 institutionsQ4 2025: 65 institutionsQ1 2026: 80 institutionsQ2 2026: 108 institutions
Value heldQ4 2025: $157.4M
Q1 2021: $0Q2 2021: $0Q3 2021: $310.7MQ4 2021: $181.8MQ1 2022: $146.8MQ2 2022: $45.7MQ3 2022: $47.8MQ4 2022: $61.0MQ1 2023: $48.4MQ2 2023: $46.8MQ3 2023: $44.0MQ4 2023: $45.5MQ1 2024: $46.2MQ2 2024: $354.8MQ3 2024: $278.2MQ4 2024: $100.3MQ1 2025: $63.4MQ2 2025: $61.9MQ3 2025: $89.7MQ4 2025: $157.4MQ1 2026: $221.2MQ2 2026: $734.3M
Institutions holding CLYM and their total value by quarter
QuarterHoldersValue
Q2 2026108$734.3M
Q1 202680$221.2M
Q4 202565$157.4M
Q3 202568$89.7M
Q2 202569$61.9M
Q1 202576$63.4M
Q4 202480$100.3M
Q3 202471$278.2M
Q2 202447$354.8M
Q1 202421$46.2M
Q4 202323$45.5M
Q3 202323$44.0M
Q2 202322$46.8M
Q1 202319$48.4M
Q4 202220$61.0M
Q3 202222$47.8M
Q2 202229$45.7M
Q1 202243$146.8M
Q4 202135$181.8M
Q3 202132$310.7M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Climb Bio, Inc.; share changes are against Q3 2025.

Institutions holding CLYM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,293,828$77.7M0.80%−20,125,439−64.1%Reduced
MPM Oncology Impact Management LP2,671,480$10.7M1.22%+2,671,480New
Price T Rowe Associates Inc1,923,639$7.70M0.00%+1,396,722+265.1%Added
ADAR1 Capital Management, LLC1,432,475$5.73M0.43%+1,298,945+972.8%Added
Vanguard Group Inc1,340,504$5.36M0.00%+24,693+1.9%Added
Affinity Asset Advisors, LLC1,300,000$5.20M0.37%00.0%Unchanged
Kynam Capital Management, LP1,028,341$4.11M0.27%00.0%Unchanged
Great Point Partners LLC979,534$3.92M1.27%+979,534New
Sphera Funds Management Ltd.932,247$3.73M0.78%+497,410+114.4%Added
Point72 Asset Management, L.P.716,680$2.87M0.00%+716,680New
Driehaus Capital Management LLC600,946$2.40M0.02%+600,946New
Two Sigma Investments, LP566,712$2.27M0.00%+454,031+402.9%Added
Peapod Lane Capital LLC565,992$2.26M1.93%+4,126+0.7%Added
Nan Fung Trinity (HK) Ltd463,654$1.85M0.15%00.0%Unchanged
Susquehanna International Group, LLP445,342$1.78M0.00%+302,892+212.6%Added
Kotler Kevin400,000$1.60M1.18%+400,000New
BlackRock, Inc.389,309$1.56M0.00%−346,194−47.1%Reduced
Renaissance Technologies LLC320,600$1.28M0.00%−216,500−40.3%Reduced
Geode Capital Management, LLC310,756$1.24M0.00%−965−0.3%Reduced
Marshall Wace, LLP304,015$1.22M0.00%+74,126+32.2%Added
Millennium Management LLC296,314$1.19M0.00%−175,390−37.2%Reduced
TD Asset Management Inc246,200$984.8K0.00%+156,800+175.4%Added
Citadel Advisors LLC239,043$956.2K0.00%+239,043New
Goldman Sachs Group Inc224,883$899.5K0.00%+151,168+205.1%Added
683 Capital Management, LLC201,652$806.6K0.07%+201,652New
Jane Street Group, LLC187,403$749.6K0.00%+107,749+135.3%Added
Bridgeway Capital Management, LLC159,300$637.2K0.01%+50,000+45.7%Added
Morgan Stanley148,538$594.2K0.00%+62,204+72.1%Added
Manufacturers Life Insurance Company, The140,617$566.6K0.00%+101,717+261.5%Added
Ameriprise Financial Inc139,529$558.1K0.00%+139,529New
State Street Corp128,900$515.6K0.00%+25,800+25.0%Added
Two Sigma Advisers, LP124,700$498.8K0.00%+43,800+54.1%Added
Northern Trust Corp124,670$498.7K0.00%−753−0.6%Reduced
Botty Investors LLC121,400$485.6K0.12%+121,400New
Squadron Capital Management LLC100,000$400.0K0.18%+100,000New
Omers Administration Corp85,466$341.9K0.00%+85,466New
Seven Fleet Capital Management LP76,400$305.6K0.21%+76,400New
UBS Group AG71,323$285.3K0.00%−334,081−82.4%Reduced
LPL Financial LLC62,000$248.0K0.00%+1,000+1.6%Added
Barclays PLC61,853$247.4K0.00%+37,100+149.9%Added
Hudson Bay Capital Management LP48,736$194.9K0.00%+48,736New
XTX Topco Ltd34,852$139.4K0.00%+5,668+19.4%Added
Qube Research & Technologies Ltd34,596$138.4K0.00%−2,006−5.5%Reduced
Citizens Financial Group Inc28,168$112.7K0.00%−17,832−38.8%Reduced
HSBC Holdings PLC24,744$99.2K0.00%+12,800+107.2%Added
Prelude Capital Management, LLC19,918$79.7K0.01%−20,800−51.1%Reduced
Balyasny Asset Management LLC14,236$56.9K0.00%+14,236New
Chicago Partners Investment Group LLC10,962$55.0K0.00%+630+6.1%Added
JustInvest LLC11,127$44.5K0.00%−3,419−23.5%Reduced
Blair William & Co11,000$44.0K0.00%+11,000New
Virtu Financial LLC10,655$43.0K0.00%+10,655New
Scientech Research LLC10,428$41.7K0.03%+10,428New
Citigroup Inc10,331$41.3K0.00%−319,217−96.9%Reduced
Persistent Asset Partners Ltd9,228$36.9K0.02%−18,993−67.3%Reduced
FMR LLC6,349$25.4K0.00%−793−11.1%Reduced
Bank of America Corp5,063$20.3K0.00%−690−12.0%Reduced
Tower Research Capital LLC (TRC)3,357$13.4K0.00%−9,887−74.7%Reduced
Harbour Investments, Inc.2,000$8.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.600$2.40K0.00%−22,000−97.3%Reduced
Nisa Investment Advisors, LLC573$2.29K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA513$2.05K0.00%−1,341−72.3%Reduced
Royal Bank of Canada408$1.00K0.00%−283−41.0%Reduced
JPMorgan Chase & Co46$1840.00%−21,966−99.8%Reduced
Deutsche Bank AG1$40.00%00.0%Unchanged
CWM, LLC29$00.00%−78−72.9%Reduced
Tang Capital Management LLC0$00.00%−1,000,000−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−547,173−100.0%Sold out
Deep Track Capital, LP0$00.00%−509,789−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−485,364−100.0%Sold out
Shay Capital LLC0$00.00%−150,000−100.0%Sold out
Diadema Partners LP0$00.00%−136,488−100.0%Sold out
Bluefin Capital Management, LLC0$00.00%−59,985−100.0%Sold out
Susquehanna Portfolio Strategies, LLC0$00.00%−18,272−100.0%Sold out
Squarepoint Ops LLC0$00.00%−17,699−100.0%Sold out
Walleye Capital LLC0$00.00%−15,000−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−11,878−100.0%Sold out
Federated Hermes, Inc.0$00.00%−4,420−100.0%Sold out
Mirae Asset Global Investments Co., Ltd.0$00.00%−2,620−100.0%Sold out
GF Fund Management Co. Ltd.0$00.00%−1,458−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−224−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−53−100.0%Sold out
Advisory Services Network, LLC0$00.00%−32−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−13−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed