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Anavex Life Sciences Corp.

AVXL
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001314052

No open-market purchases or sales by Anavex Life Sciences Corp. insiders were filed in the last 90 days; 180 institutions reported holding it in 13F filings for Q2 2026, worth $95.8M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Anavex Life Sciences Corp. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
186
+3 vs. Q3 2025
Shares held
37.9M
+5.30M (+16.3%) vs. Q3 2025
Total value
$136.1M
−$151.3M (−52.7%) vs. Q3 2025
New holders
29
62 more added
Sold out
26
54 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AVXL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 186 institutions
Q1 2021: 108 institutionsQ2 2021: 127 institutionsQ3 2021: 136 institutionsQ4 2021: 149 institutionsQ1 2022: 139 institutionsQ2 2022: 150 institutionsQ3 2022: 148 institutionsQ4 2022: 139 institutionsQ1 2023: 141 institutionsQ2 2023: 144 institutionsQ3 2023: 143 institutionsQ4 2023: 153 institutionsQ1 2024: 147 institutionsQ2 2024: 141 institutionsQ3 2024: 145 institutionsQ4 2024: 169 institutionsQ1 2025: 181 institutionsQ2 2025: 178 institutionsQ3 2025: 186 institutionsQ4 2025: 186 institutionsQ1 2026: 190 institutionsQ2 2026: 180 institutions
Value heldQ4 2025: $136.1M
Q1 2021: $271.9MQ2 2021: $492.2MQ3 2021: $370.1MQ4 2021: $383.2MQ1 2022: $308.2MQ2 2022: $249.4MQ3 2022: $251.4MQ4 2022: $248.7MQ1 2023: $232.3MQ2 2023: $205.6MQ3 2023: $164.1MQ4 2023: $240.8MQ1 2024: $161.3MQ2 2024: $113.3MQ3 2024: $153.2MQ4 2024: $316.5MQ1 2025: $269.2MQ2 2025: $301.9MQ3 2025: $289.3MQ4 2025: $136.1MQ1 2026: $122.7MQ2 2026: $95.8M
Institutions holding AVXL and their total value by quarter
QuarterHoldersValue
Q2 2026180$95.8M
Q1 2026190$122.7M
Q4 2025186$136.1M
Q3 2025186$289.3M
Q2 2025178$301.9M
Q1 2025181$269.2M
Q4 2024169$316.5M
Q3 2024145$153.2M
Q2 2024141$113.3M
Q1 2024147$161.3M
Q4 2023153$240.8M
Q3 2023143$164.1M
Q2 2023144$205.6M
Q1 2023141$232.3M
Q4 2022139$248.7M
Q3 2022148$251.4M
Q2 2022150$249.4M
Q1 2022139$308.2M
Q4 2021149$383.2M
Q3 2021136$370.1M
Q2 2021127$492.2M
Q1 2021108$271.9M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Anavex Life Sciences Corp.; share changes are against Q3 2025.

Institutions holding AVXL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.7,526,130$26.8M0.00%+337,861+4.7%Added
Vanguard Group Inc5,028,534$17.9M0.00%−75,976−1.5%Reduced
State Street Corp4,383,406$15.6M0.00%+1,096,288+33.4%Added
Geode Capital Management, LLC2,022,912$7.20M0.00%−4,415−0.2%Reduced
Two Sigma Investments, LP1,653,696$5.89M0.01%+616,742+59.5%Added
Nwam LLC870,796$4.37M0.24%−3,487−0.4%Reduced
Two Sigma Advisers, LP1,209,570$4.31M0.01%+451,070+59.5%Added
Summit Financial, LLC903,392$3.22M0.05%+459,121+103.3%Added
Goldman Sachs Group Inc872,968$3.11M0.00%+569,579+187.7%Added
Jane Street Group, LLC768,955$2.74M0.00%+550,738+252.4%Added
Northern Trust Corp738,242$2.63M0.00%−34,770−4.5%Reduced
Charles Schwab Investment Management Inc668,956$2.38M0.00%−48,422−6.7%Reduced
LPL Financial LLC528,782$1.88M0.00%−5,537−1.0%Reduced
Bank of America Corp524,189$1.87M0.00%+353,303+206.7%Added
Barclays PLC493,172$1.76M0.00%+231,892+88.8%Added
Morgan Stanley474,856$1.69M0.00%−85,292−15.2%Reduced
UBS Group AG459,394$1.64M0.00%−32,583−6.6%Reduced
Susquehanna International Group, LLP439,499$1.56M0.00%−164,319−27.2%Reduced
Private Advisor Group, LLC419,800$1.49M0.01%−35,325−7.8%Reduced
Qube Research & Technologies Ltd388,718$1.38M0.00%+388,718New
Federated Hermes, Inc.367,841$1.31M0.00%+367,841New
Caption Management, LLC354,838$1.26M0.06%+354,838New
National Bank of Canada305,200$1.09M0.00%−87,971−22.4%Reduced
Point72 Asset Management, L.P.278,018$989.7K0.00%+278,018New
Wellington Management Group LLP272,231$969.1K0.00%−16,582−5.7%Reduced
Bank of New York Mellon Corp244,055$868.8K0.00%−3,959−1.6%Reduced
PVG Asset Management Corp216,295$770.0K1.64%+83,147+62.4%Added
Marshall Wace, LLP182,190$648.6K0.00%00.0%Unchanged
Nuveen, LLC168,377$599.4K0.00%00.0%Unchanged
Swiss National Bank164,400$585.3K0.00%00.0%Unchanged
UBS Asset Management Americas Inc162,124$577.2K0.00%+710.0%Added
Rafferty Asset Management, LLC156,301$556.4K0.00%+47,873+44.2%Added
Sculptor Capital LP155,900$555.0K0.01%00.0%Unchanged
Gsa Capital Partners LLP155,879$555.0K0.05%+92,799+147.1%Added
AQR Capital Management LLC149,815$533.3K0.00%+121,779+434.4%Added
Apella Capital, LLC138,006$491.3K0.01%+38,482+38.7%Added
Wells Fargo & Company133,820$476.4K0.00%+19,950+17.5%Added
Sheets Smith Wealth Management117,696$419.0K0.05%+117,696New
180 Wealth Advisors, LLC117,380$417.9K0.05%+74,345+172.8%Added
Alliancebernstein L.P.115,200$410.1K0.00%00.0%Unchanged
Citadel Advisors LLC113,739$404.9K0.00%−81,986−41.9%Reduced
Rhumbline Advisers107,404$382.3K0.00%−16,592−13.4%Reduced
Stifel Financial Corp101,020$359.6K0.00%+49,229+95.1%Added
XTX Topco Ltd99,058$352.6K0.01%+17,356+21.2%Added
Canada Pension Plan Investment Board95,900$341.4K0.00%+95,900New
Envestnet Asset Management Inc87,674$312.1K0.00%+27,731+46.3%Added
Legal & General Group Plc86,900$309.7K0.00%+350.0%Added
Hikari Power Ltd85,585$305.0K0.02%00.0%Unchanged
California State Teachers Retirement System78,005$277.7K0.00%−350−0.4%Reduced
Alps Advisors Inc73,361$261.2K0.00%+34,755+90.0%Added
Creative Planning72,745$259.0K0.00%−4,388−5.7%Reduced
Franklin Resources Inc72,560$258.3K0.00%−302,664−80.7%Reduced
Deutsche Bank AG69,547$247.6K0.00%−3,127−4.3%Reduced
Ameriprise Financial Inc68,525$243.9K0.00%−17,270−20.1%Reduced
Gladstone Institutional Advisory LLC68,504$243.9K0.01%+8,975+15.1%Added
Carnegie Capital Asset Management, LLC67,578$240.6K0.00%−15,200−18.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)64,947$231.2K0.00%+21,132+48.2%Added
The PNC Financial Services Group, Inc.63,687$226.7K0.00%−341−0.5%Reduced
Profund Advisors LLC57,972$206.4K0.01%+34,072+142.6%Added
JPMorgan Chase & Co56,537$201.3K0.00%+11,472+25.5%Added
Squarepoint Ops LLC56,363$200.7K0.00%+56,363New
Foster Victor Wealth Advisors, LLC39,925$200.0K0.01%−553−1.4%Reduced
Man Group plc55,223$196.6K0.00%+30,838+126.5%Added
Brevan Howard Capital Management LP54,727$194.8K0.00%+37,503+217.7%Added
Independent Advisor Alliance50,076$178.3K0.00%+2,277+4.8%Added
Mirae Asset Global ETFs Holdings Ltd.47,927$172.8K0.00%+3,846+8.7%Added
Geneos Wealth Management Inc.48,200$171.6K0.00%+5,800+13.7%Added
Price T Rowe Associates Inc46,279$165.0K0.00%+669+1.5%Added
October Effect Ltd46,280$164.8K0.18%−198,941−81.1%Reduced
Schonfeld Strategic Advisors LLC46,195$164.5K0.00%+46,195New
Quantinno Capital Management LP45,711$162.7K0.00%+11,437+33.4%Added
Invesco Ltd.45,487$161.9K0.00%−11,212−19.8%Reduced
Cetera Investment Advisers42,856$152.6K0.00%+14,598+51.7%Added
Snowden Capital Advisors LLC42,717$152.1K0.00%+42,717New
Manufacturers Life Insurance Company, The39,510$140.7K0.00%−2,216−5.3%Reduced
Mariner, LLC38,821$138.2K0.00%+12,465+47.3%Added
Opus Capital Group, LLC37,700$134.0K0.01%+3,000+8.6%Added
Janus Henderson Group PLC37,000$131.9K0.00%00.0%Unchanged
Intech Investment Management LLC36,945$131.5K0.00%00.0%Unchanged
MetLife Investment Management35,720$127.2K0.00%−8,885−19.9%Reduced
RSM US Wealth Management LLC31,991$121.6K0.00%−957−2.9%Reduced
Bank of Montreal32,440$115.5K0.00%+9,485+41.3%Added
Advisor Group Holdings, Inc.31,735$113.0K0.00%−10,678−25.2%Reduced
Forum Financial Management, LP30,140$107.3K0.00%00.0%Unchanged
HSBC Holdings PLC28,784$103.6K0.00%+28,784New
GWM Advisors LLC28,231$100.5K0.00%+26,605+1,636.2%Added
Deeter Investments LLP98,311$99.3K0.02%+98,311New
Dimensional Fund Advisors LP27,232$96.9K0.00%+27,232New
Citigroup Inc25,645$91.3K0.00%+14,153+123.2%Added
Renaissance Technologies LLC25,422$90.5K0.00%+25,422New
Axq Capital, LP24,996$89.0K0.02%+5,895+30.9%Added
Arizona State Retirement System23,386$83.3K0.00%−1,850−7.3%Reduced
Atria Investments LLC23,340$83.1K0.00%+2,429+11.6%Added
Police & Firemen's Retirement System of New Jersey23,092$82.2K0.00%00.0%Unchanged
Beacon Pointe Advisors, LLC23,000$81.9K0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.22,060$79.0K0.00%+955+4.5%Added
Two Sigma Securities, LLC21,468$76.4K0.01%+21,468New
Yukon Wealth Management, Inc.18,045$74.5K0.04%+1,053+6.2%Added
Dana Investment Advisors, Inc.20,406$72.6K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System20,345$72.4K0.00%00.0%Unchanged