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Assembly Biosciences, Inc.

ASMB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001426800

No open-market purchases or sales by Assembly Biosciences, Inc. insiders were filed in the last 90 days; 92 institutions reported holding it in 13F filings for Q2 2026, worth $514.8M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Assembly Biosciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
75
+7 vs. Q4 2025
Shares held
13.6M
+417.3K (+3.2%) vs. Q4 2025
Total value
$376.4M
−$70.8M (−15.8%) vs. Q4 2025
New holders
17
28 more added
Sold out
10
17 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ASMB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 75 institutions
Q1 2021: 107 institutionsQ2 2021: 91 institutionsQ3 2021: 65 institutionsQ4 2021: 62 institutionsQ1 2022: 54 institutionsQ2 2022: 54 institutionsQ3 2022: 50 institutionsQ4 2022: 40 institutionsQ1 2023: 38 institutionsQ2 2023: 32 institutionsQ3 2023: 32 institutionsQ4 2023: 45 institutionsQ1 2024: 24 institutionsQ2 2024: 27 institutionsQ3 2024: 30 institutionsQ4 2024: 35 institutionsQ1 2025: 37 institutionsQ2 2025: 33 institutionsQ3 2025: 57 institutionsQ4 2025: 69 institutionsQ1 2026: 75 institutionsQ2 2026: 92 institutions
Value heldQ1 2026: $376.4M
Q1 2021: $133.6MQ2 2021: $105.1MQ3 2021: $79.0MQ4 2021: $53.8MQ1 2022: $39.3MQ2 2022: $36.1MQ3 2022: $27.2MQ4 2022: $18.4MQ1 2023: $10.1MQ2 2023: $12.0MQ3 2023: $8.44MQ4 2023: $7.09MQ1 2024: $8.61MQ2 2024: $16.1MQ3 2024: $15.5MQ4 2024: $50.3MQ1 2025: $30.4MQ2 2025: $57.0MQ3 2025: $324.9MQ4 2025: $466.7MQ1 2026: $376.4MQ2 2026: $514.8M
Institutions holding ASMB and their total value by quarter
QuarterHoldersValue
Q2 202692$514.8M
Q1 202675$376.4M
Q4 202569$466.7M
Q3 202557$324.9M
Q2 202533$57.0M
Q1 202537$30.4M
Q4 202435$50.3M
Q3 202430$15.5M
Q2 202427$16.1M
Q1 202424$8.61M
Q4 202345$7.09M
Q3 202332$8.44M
Q2 202332$12.0M
Q1 202338$10.1M
Q4 202240$18.4M
Q3 202250$27.2M
Q2 202254$36.1M
Q1 202254$39.3M
Q4 202162$53.8M
Q3 202165$79.0M
Q2 202191$105.1M
Q1 2021107$133.6M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Assembly Biosciences, Inc.; share changes are against Q4 2025.

Institutions holding ASMB in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada16$00.00%+16New
Allworth Financial LP29$8050.00%−3−9.4%Reduced
EverSource Wealth Advisors, LLC55$1.53K0.00%00.0%Unchanged
Fifth Third Bancorp57$1.58K0.00%+57New
US Bancorp59$1.64K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.100$2.77K0.00%00.0%Unchanged
Accent Capital Management, LLC142$3.94K0.00%+142New
BNP Paribas Arbitrage, SA149$4.13K0.00%+147+7,350.0%Added
Rhumbline Advisers190$5.27K0.00%00.0%Unchanged
Aquatic Capital Management LLC220$6.11K0.00%+220New
Northwestern Mutual Wealth Management Co260$7.21K0.00%00.0%Unchanged
UBS Group AG364$10.1K0.00%−9,415−96.3%Reduced
Tower Research Capital LLC (TRC)544$15.1K0.00%−63−10.4%Reduced
Vanguard Global Advisers, LLC4,615$128.1K0.00%+4,615New
Citigroup Inc6,483$179.9K0.00%+4,282+194.5%Added
Virtus Investment Advisers, Inc.7,553$209.6K0.06%+184+2.5%Added
Omers Administration Corp8,100$224.8K0.00%−7,498−48.1%Reduced
Canada Pension Plan Investment Board8,500$235.9K0.00%+5,000+142.9%Added
American Century Companies Inc9,154$254.0K0.00%+9,154New
Engineers Gate Manager LP9,423$261.5K0.00%−952−9.2%Reduced
XTX Topco Ltd10,785$299.3K0.01%+10,785New
Bank of America Corp10,902$302.5K0.00%+5,792+113.3%Added
Jump Financial, LLC10,917$302.9K0.00%+10,917New
Brevan Howard Capital Management LP11,112$308.4K0.00%+11,112New
EntryPoint Capital, LLC12,384$343.7K0.10%+12,384New
Susquehanna Portfolio Strategies, LLC14,100$391.3K0.01%+197+1.4%Added
Renaissance Technologies LLC15,651$434.3K0.00%+6,411+69.4%Added
Hudson Bay Capital Management LP16,799$466.2K0.00%+1,749+11.6%Added
Vanguard Portfolio Management LLC17,723$491.8K0.00%+17,723New
Federated Hermes, Inc.18,904$524.6K0.00%−6,490−25.6%Reduced
Palumbo Wealth Management LLC19,643$545.1K0.13%−17,662−47.3%Reduced
ADAR1 Capital Management, LLC19,947$553.5K0.03%+200+1.0%Added
Two Sigma Investments, LP20,550$570.3K0.00%+20,550New
Connor, Clark & Lunn Investment Management Ltd.21,761$603.9K0.00%+959+4.6%Added
Trexquant Investment LP22,741$631.1K0.00%−5,535−19.6%Reduced
Squarepoint Ops LLC23,804$660.6K0.00%+23,804New
Citadel Advisors LLC25,437$705.9K0.00%−7,429−22.6%Reduced
Wellington Management Group LLP26,496$735.3K0.00%+26,496New
Barclays PLC27,050$750.6K0.00%+2,309+9.3%Added
683 Capital Management, LLC27,863$773.2K0.07%00.0%Unchanged
Susquehanna International Group, LLP32,949$914.3K0.00%−47,445−59.0%Reduced
Morgan Stanley33,055$917.3K0.00%+10,521+46.7%Added
Jane Street Group, LLC34,499$957.3K0.00%−19,203−35.8%Reduced
Goldman Sachs Group Inc36,205$1.00M0.00%+1,411+4.1%Added
Arrowstreet Capital, Limited Partnership39,446$1.09M0.00%+1,634+4.3%Added
Eversept Partners, LP40,889$1.13M0.07%−118,787−74.4%Reduced
Northern Trust Corp41,014$1.14M0.00%−213−0.5%Reduced
Gsa Capital Partners LLP45,049$1.25M0.08%+32,350+254.7%Added
Monimus Capital Management, LP48,390$1.34M0.37%+10,089+26.3%Added
JPMorgan Chase & Co53,962$1.44M0.00%+5,803+12.0%Added
Seven Fleet Capital Management LP56,147$1.56M0.49%−17,615−23.9%Reduced
State Street Corp56,689$1.57M0.00%+3,700+7.0%Added
Qube Research & Technologies Ltd69,256$1.92M0.00%+27,071+64.2%Added
Vanguard Fiduciary Trust Co71,606$1.99M0.00%+71,606New
HighVista Strategies LLC74,735$2.07M0.57%+74,735New
Caption Management, LLC81,841$2.27M0.11%−24,750−23.2%Reduced
Schonfeld Strategic Advisors LLC120,500$3.34M0.03%+66,265+122.2%Added
Geode Capital Management, LLC132,971$3.69M0.00%+1,664+1.3%Added
Patient Square Capital LP136,315$3.78M0.67%+9,315+7.3%Added
Adage Capital Partners GP, L.L.C.161,000$4.47M0.01%00.0%Unchanged
Marshall Wace, LLP163,400$4.53M0.00%+34,325+26.6%Added
B Group, Inc.175,706$4.88M3.61%00.0%Unchanged
StemPoint Capital LP185,435$5.15M0.99%+28,707+18.3%Added
BlackRock, Inc.202,743$5.63M0.00%+10,447+5.4%Added
Millennium Management LLC233,650$6.48M0.00%+135,429+137.9%Added
Blackstone Group Inc.296,855$8.24M0.03%−21,899−6.9%Reduced
Point72 Asset Management, L.P.344,105$9.55M0.02%−256,504−42.7%Reduced
Parkman Healthcare Partners LLC411,227$11.4M1.18%+161,870+64.9%Added
Vanguard Capital Management LLC490,447$13.6M0.00%+490,447New
Paradigm Biocapital Advisors LP665,251$18.5M0.38%00.0%Unchanged
Janus Henderson Group PLC849,309$23.5M0.01%+11,384+1.4%Added
Commodore Capital LP1,000,000$27.8M1.61%00.0%Unchanged
Ra Capital Management, L.P.1,020,410$28.3M0.30%00.0%Unchanged
Farallon Capital Management, L.L.C.1,227,590$34.1M0.20%00.0%Unchanged
Gilead Sciences, Inc.4,505,391$125.0M5.90%00.0%Unchanged
Franklin Resources Inc0$00.00%−210,528−100.0%Sold out
Superstring Capital Management LP0$00.00%−65,273−100.0%Sold out
EAM Investors, LLC0$00.00%−29,523−100.0%Sold out
Ellsworth Advisors, LLC0$00.00%−29,735−100.0%Sold out
SEI Investments Co0$00.00%−17,745−100.0%Sold out
Raymond James Financial Inc0$00.00%−13,082−100.0%Sold out
Acadian Asset Management LLC0$00.00%−12,446−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−6,704−100.0%Sold out
Farther Finance Advisors, LLC0$00.00%−154−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−22−100.0%Sold out
Vanguard Group Inc––––Not filed