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Aprea Therapeutics, Inc.

APRE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001781983

No open-market purchases or sales by Aprea Therapeutics, Inc. insiders were filed in the last 90 days; 27 institutions reported holding it in 13F filings for Q2 2026, worth $1.90M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Aprea Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
22
+1 vs. Q4 2025
Shares held
2.24M
+606.9K (+37.1%) vs. Q4 2025
Total value
$1.71M
+$315.5K (+22.6%) vs. Q4 2025
New holders
7
4 more added
Sold out
6
5 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 22 institutions
Q1 2021: 67 institutionsQ2 2021: 50 institutionsQ3 2021: 39 institutionsQ4 2021: 41 institutionsQ1 2022: 40 institutionsQ2 2022: 34 institutionsQ3 2022: 27 institutionsQ4 2022: 25 institutionsQ1 2023: 18 institutionsQ2 2023: 19 institutionsQ3 2023: 21 institutionsQ4 2023: 20 institutionsQ1 2024: 24 institutionsQ2 2024: 28 institutionsQ3 2024: 22 institutionsQ4 2024: 26 institutionsQ1 2025: 26 institutionsQ2 2025: 23 institutionsQ3 2025: 23 institutionsQ4 2025: 22 institutionsQ1 2026: 22 institutionsQ2 2026: 27 institutions
Value heldQ1 2026: $1.71M
Q1 2021: $45.4MQ2 2021: $31.9MQ3 2021: $25.6MQ4 2021: $10.4MQ1 2022: $4.50MQ2 2022: $1.52MQ3 2022: $1.11MQ4 2022: $521.3KQ1 2023: $3.77MQ2 2023: $2.78MQ3 2023: $3.66MQ4 2023: $4.36MQ1 2024: $10.8MQ2 2024: $8.48MQ3 2024: $5.50MQ4 2024: $6.83MQ1 2025: $3.78MQ2 2025: $3.07MQ3 2025: $2.39MQ4 2025: $1.45MQ1 2026: $1.71MQ2 2026: $1.90M
Institutions holding APRE and their total value by quarter
QuarterHoldersValue
Q2 202627$1.90M
Q1 202622$1.71M
Q4 202522$1.45M
Q3 202523$2.39M
Q2 202523$3.07M
Q1 202526$3.78M
Q4 202426$6.83M
Q3 202422$5.50M
Q2 202428$8.48M
Q1 202424$10.8M
Q4 202320$4.36M
Q3 202321$3.66M
Q2 202319$2.78M
Q1 202318$3.77M
Q4 202225$521.3K
Q3 202227$1.11M
Q2 202234$1.52M
Q1 202240$4.50M
Q4 202141$10.4M
Q3 202139$25.6M
Q2 202150$31.9M
Q1 202167$45.4M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Aprea Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding APRE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
AIGH Capital Management LLC1,015,541$774.8K0.16%+645,000+174.1%Added
Vestal Point Capital, LP350,000$267.0K0.01%+350,000New
Sphera Funds Management Ltd.270,000$206.0K0.04%00.0%Unchanged
Nantahala Capital Management, LLC205,760$157.0K0.01%00.0%Unchanged
Geode Capital Management, LLC119,131$90.9K0.00%+78,181+190.9%Added
Scientech Research LLC60,281$46.0K0.04%+60,281New
BNP Paribas Arbitrage, SA39,817$30.4K0.00%+12,485+45.7%Added
Vanguard Fiduciary Trust Co38,464$29.3K0.00%+38,464New
Renaissance Technologies LLC25,100$19.1K0.00%+25,100New
Morgan Stanley22,330$17.0K0.00%−54,700−71.0%Reduced
LPL Financial LLC21,052$16.1K0.00%−5,000−19.2%Reduced
Vanguard Capital Management LLC19,622$15.0K0.00%+19,622New
HighTower Advisors, LLC13,864$10.6K0.00%00.0%Unchanged
Two Sigma Securities, LLC13,500$10.3K0.00%+13,500New
Susquehanna International Group, LLP13,018$9.93K0.00%+13,018New
BlackRock, Inc.8,504$6.49K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)5,127$3.91K0.00%−2,700−34.5%Reduced
UBS Group AG2,153$1.64K0.00%−308−12.5%Reduced
Group One Trading, L.P.577$4400.00%00.0%Unchanged
Advisor Group Holdings, Inc.295$2250.00%−5−1.7%Reduced
WealthCollab, LLC158$1210.00%00.0%Unchanged
SBI Securities Co., Ltd.16$120.00%+1+6.7%Added
Murchinson Ltd.0$00.00%−340,139−100.0%Sold out
DRW Securities, LLC0$00.00%−120,651−100.0%Sold out
Citadel Advisors LLC0$00.00%−51,041−100.0%Sold out
Jane Street Group, LLC0$00.00%−46,621−100.0%Sold out
XTX Topco Ltd0$00.00%−24,304−100.0%Sold out
Bank of America Corp0$00.00%−3,299−100.0%Sold out
Vanguard Group Inc––––Not filed