Aprea Therapeutics, Inc.
APRE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001781983
No open-market purchases or sales by Aprea Therapeutics, Inc. insiders were filed in the last 90 days; 27 institutions reported holding it in 13F filings for Q2 2026, worth $1.90M in total; no superinvestor holds it.
Holders of 5% or more of APRE
Holders whose latest Schedule 13D or 13G filing reports 5% or more of Aprea Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| Lytton Laurence W | 13G | 9.90%681.8K shares | New | Nov 17, 20251 filing | Nov 17, 2025 | SEC |
| Hirschman Orin | 13G/A | 9.90%651.7K shares | 0.00 ppfrom 9.90% | Feb 10, 20252 filings | Jan 28, 2026 | SEC |
Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.
13D and 13G filings
11 Schedule 13D and 13G filings on Aprea Therapeutics, Inc., newest first, including old-format filings without a stake.
| Filed (ET) | Filer | Form | Stake | Change | Event date | Filing |
|---|---|---|---|---|---|---|
| Feb 13, 20265:02 PM ET | Nantahala Capital Management, LLCand 2 others | 13G/A | 4.50%411.5K shares | −2.80 ppfrom 7.30%Below 5% | Dec 31, 2025 | SEC |
| Jan 28, 20262:02 PM ET | Hirschman Orinand 1 other | 13G/A | 9.90%651.7K shares | 0.00 ppfrom 9.90% | Dec 31, 2025 | SEC |
| Nov 17, 20257:16 PM ET | Lytton Laurence W | 13G | 9.90%681.8K shares | New | Nov 13, 2025 | SEC |
| Nov 12, 20258:00 AM ET | Sio Capital Management, LLC | 13G/A | 1.93%112.2K shares | −3.12 ppfrom 5.05%Below 5% | Sep 30, 2025 | SEC |
| Aug 13, 20252:00 PM ET | Sio Capital Management, LLC | 13G/A | 5.05%279.4K shares | +0.01 ppfrom 5.04% | Jun 30, 2025 | SEC |
| May 14, 20254:04 PM ET | Stonepine Capital Management, LLCand 3 others | 13G/A | 4.30%239.4K shares | −0.80 ppfrom 5.10%Below 5% | Mar 31, 2025 | SEC |
| Apr 8, 20253:14 PM ET | Sio Capital Management, LLC | 13G/A | 5.04%276.6K shares | −0.05 ppfrom 5.09% | Mar 31, 2025 | SEC |
| Feb 13, 202512:15 PM ET | Stonepine Capital Management, LLCand 3 others | 13G/A | 5.10%286.4K shares | – | Dec 31, 2024 | SEC |
| Feb 10, 202512:56 PM ET | Sio Capital Management, LLC | 13G/A | 5.09%276.6K shares | – | Dec 31, 2024 | SEC |
| Feb 10, 20258:36 AM ET | Hirschman Orinand 1 other | 13G/A | 9.90%539.3K shares | – | Dec 31, 2024 | SEC |
| Nov 14, 20244:53 PM ET | Nantahala Capital Management, LLCand 2 others | 13G | 7.30%411.5K shares | New | Sep 30, 2024 | SEC |
Form 144: proposed insider sales
Notices from officers, directors and other affiliates planning to sell Aprea Therapeutics, Inc. shares.
No Form 144 notices for Aprea Therapeutics, Inc. are on file.