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StemPoint Capital LP

SEC CIK
0001952142
Latest filing
Aug 14, 2026

Holdings in Q4 2025

Holdings as of Dec 31, 2025, filed Feb 17, 2026. Long positions only; changes compare share counts with Q3 2025.

Institution overview
Positions
75
−1 vs. Q3 2025
Portfolio value
$582.7M
+$86.8M (+17.5%) vs. Q3 2025
Filed
Feb 17, 2026
SEC
Holdings of StemPoint Capital LP in Q4 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
ABVXAbivax S.A.SPONSORED ADS391,783$52.8M9.1%+225,510+135.6%AddedHistory
SRRKScholar Rock Holding CorpCOM886,893$39.1M6.7%+160,689+22.1%AddedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS1,154,114$28.9M5.0%+498,729+76.1%AddedHistory
SNDXSyndax Pharmaceuticals IncCOM1,339,379$28.1M4.8%−26,826−2.0%ReducedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS351,073$24.4M4.2%+221,738+171.4%AddedHistory
ACLXArcellx, Inc.COMMON STOCK332,860$21.7M3.7%+321,484+2,826.0%AddedHistory
ROIVRoivant Sciences Ltd.SHS966,698$21.0M3.6%−3,230,489−77.0%ReducedHistory
TERNTerns Pharmaceuticals, Inc.COM429,198$17.3M3.0%+339,581+378.9%AddedHistory
TWSTTwist Bioscience CorpCOM518,355$16.4M2.8%+518,355NewHistory
IMVTImmunovant, Inc.COM644,959$16.4M2.8%−944,621−59.4%ReducedHistory
DYNDyne Therapeutics, Inc.COM835,200$16.3M2.8%+360,588+76.0%AddedHistory
XENEXenon Pharmaceuticals Inc.COM348,605$15.6M2.7%+156,310+81.3%AddedHistory
SRZNSurrozen, Inc.COM NEW619,766$12.7M2.2%−93,697−13.1%ReducedHistory
CELCCelcuity Inc.COM118,333$11.8M2.0%−18,377−13.4%ReducedHistory
MLYSMineralys Therapeutics, Inc.COM290,049$10.5M1.8%+131,937+83.4%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM17,736$10.3M1.8%+9,529+116.1%AddedHistory
ADPTAdaptive Biotechnologies CorpCOM606,825$9.85M1.7%+606,825NewHistory
PALIPalisade Bio, Inc.COM4,192,375$9.85M1.7%+4,192,375NewHistory
CYTKCytokinetics IncCOM NEW146,978$9.34M1.6%+146,978NewHistory
EWTXEdgewise Therapeutics, Inc.COM360,876$8.96M1.5%+360,876NewHistory
DRUGBright Minds Biosciences Inc.COM NEW97,340$7.60M1.3%+97,340NewHistory
NKTRNektar TherapeuticsCOM NEW178,274$7.54M1.3%+125,073+235.1%AddedHistory
JNJJohnson & JohnsonStock35,000$7.24M1.2%+35,000NewHistory
DNLIDenali Therapeutics Inc.COM419,058$6.92M1.2%−1,315,601−75.8%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM565,140$6.83M1.2%+288,256+104.1%AddedHistory
CLPTClearPoint Neuro, Inc.COM481,858$6.59M1.1%+465,207+2,793.9%AddedHistory
ARQTArcutis Biotherapeutics, Inc.COM224,740$6.53M1.1%−187,153−45.4%ReducedHistory
EYPTEyePoint, Inc.COM NEW353,849$6.46M1.1%+353,849NewHistory
IMTXImmatics N.V.SHS610,308$6.41M1.1%+610,308NewHistory
OCULOcular Therapeutix, IncCOM522,693$6.35M1.1%+163,223+45.4%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM58,915$6.31M1.1%−32,529−35.6%ReducedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW21,067$6.21M1.1%+21,067NewHistory
APGEApogee Therapeutics, Inc.COM80,574$6.08M1.0%+80,574NewHistory
INCYIncyte CorpCOM61,435$6.07M1.0%+17,681+40.4%AddedHistory
IDYAIDEAYA Biosciences, Inc.COM161,659$5.59M1.0%−210,166−56.5%ReducedHistory
ASMBAssembly Biosciences, Inc.COM NEW156,728$5.33M0.9%+90,598+137.0%AddedHistory
MAZEMaze Therapeutics, Inc.COM125,877$5.22M0.9%+125,877NewHistory
PTGXProtagonist Therapeutics, IncCOM59,430$5.19M0.9%+11,476+23.9%AddedHistory
LLYEli Lilly & CoStock4,759$5.11M0.9%+4,759NewHistory
TRVITrevi Therapeutics, Inc.COM399,557$5.00M0.9%+48,847+13.9%AddedHistory
RVMDRevolution Medicines, Inc.COM62,032$4.94M0.8%−123,348−66.5%ReducedHistory
VRDNViridian Therapeutics, Inc.COM154,320$4.80M0.8%+154,320NewHistory
ABUSArbutus Biopharma CorpCOM986,751$4.75M0.8%+781,363+380.4%AddedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD348,401$4.59M0.8%+348,401NewHistory
CTMXCytomX Therapeutics, Inc.COM1,036,311$4.41M0.8%+1,036,311NewHistory
XFORX4 Pharmaceuticals, IncCOM NEW898,465$3.59M0.6%+343,054+61.8%AddedHistory
WHWKWhitehawk Therapeutics, Inc.COM1,458,807$3.53M0.6%+1,034,725+244.0%AddedHistory
DNTHDianthus Therapeutics, Inc.COM79,284$3.27M0.6%+37,902+91.6%AddedHistory
ASNDAscendis Pharma A/SSPONSORED ADR14,842$3.16M0.5%−307−2.0%ReducedHistory
RGENRepligen CorpCOM15,707$2.57M0.4%+15,707NewHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES73,106$2.56M0.4%−77,467−51.4%ReducedHistory
MBXMBX Biosciences, Inc.COM78,553$2.48M0.4%+3,553+4.7%AddedHistory
QNCXQuince Therapeutics, Inc.COM739,264$2.48M0.4%+739,264NewHistory
AVTXAvalo Therapeutics, Inc.COM NEW135,552$2.46M0.4%+135,552NewHistory
IVVDInvivyd, Inc.COM989,822$2.44M0.4%+711,214+255.3%AddedHistory
MGTXMeiraGTx Holdings plcCOM287,689$2.29M0.4%+205,831+251.4%AddedHistory
IVAInventiva S.A.ADS467,242$2.17M0.4%+436,418+1,415.8%AddedHistory
ABBVAbbVie Inc.Stock9,325$2.13M0.4%+9,325NewHistory
ADCTADC Therapeutics SASHS502,570$1.77M0.3%+219,284+77.4%AddedHistory
MPLTMapLight Therapeutics, Inc.COM100,000$1.76M0.3%+100,000NewHistory
PHVSPharvaris N.V.COM58,389$1.62M0.3%+58,389NewHistory
LEGNLegend Biotech CorpSPONSORED ADS73,328$1.59M0.3%+73,328NewHistory
BLTEBelite Bio, IncSPONSORED ADS9,163$1.47M0.3%+9,163NewHistory
XLOXilio Therapeutics, Inc.COM2,030,028$1.30M0.2%+2,030,028NewHistory
EVMNEvommune, Inc.COM SHS68,196$1.17M0.2%+68,196NewHistory
BBOTBridgeBio Oncology Therapeutics, Inc.COM NEW86,517$1.08M0.2%−100,097−53.6%ReducedHistory
SYRESpyre Therapeutics, Inc.COM NEW32,377$1.06M0.2%+32,377NewHistory
QUREuniQure N.V.SHS43,485$1.04M0.2%−478,670−91.7%ReducedHistory
TSHATaysha Gene Therapies, Inc.COM SHS182,130$1.00M0.2%−657,539−78.3%ReducedHistory
GLUEMonte Rosa Therapeutics, Inc.COM61,577$965.5K0.2%+61,577NewHistory
SABSSAB Biotherapeutics, Inc.COM NEW146,558$548.1K0.1%+146,558NewHistory
VNDAVanda Pharmaceuticals Inc.COM58,989$520.3K0.1%+58,989NewHistory
CAPRCapricor Therapeutics, Inc.COM NEW17,853$515.2K0.1%+17,853NewHistory
KTTAPasithea Therapeutics Corp.COM NEW355,082$458.1K0.1%+355,082NewHistory
VTGNVistagen Therapeutics, Inc.COM616,749$142.1K<0.1%−1,871,936−75.2%ReducedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of StemPoint Capital LP in Q4 2025
SecurityClassPutsCalls
SRRKScholar Rock Holding CorpCOM–$484.8K
CNTACentessa Pharmaceuticals plcSPONSORED ADS–$26.3K

Sold out since Q3 2025 (33)

Positions held at the end of Q3 2025 that are gone from this filing.

Positions of StemPoint Capital LP sold out since Q3 2025
SecurityClassShares in Q3 2025Value in Q3 2025% of portfolio in Q3 2025History
WVEWave Life Sciences, Inc.SHS2,110,152$15.4M3.1%History
BHVNBiohaven Ltd.COM1,017,311$15.3M3.1%History
CDTXCidara Therapeutics, Inc.COM NEW152,325$14.6M2.9%History
ARGXArgenx SESPONSORED ADR12,465$9.19M1.9%History
RZLTRezolute, Inc.COM NEW917,630$8.63M1.7%History
GHRSGH Research PLCORDINARY SHARES545,275$7.80M1.6%History
ALKSAlkermes plc.SHS241,637$7.25M1.5%History
BBIOBridgeBio Pharma, Inc.COM127,435$6.62M1.3%History
INSMINSMED IncCOM PAR $.0143,419$6.25M1.3%History
AKROAkero Therapeutics, Inc.COM121,410$5.76M1.2%History
JAZZJazz Pharmaceuticals plcSHS USD39,072$5.15M1.0%History
Avidity Biosciences, Inc.05370A108COM114,053$4.97M1.0%–
TECXTectonic Therapeutic, Inc.COM188,999$2.97M0.6%History
HROWHarrow, Inc.COM57,619$2.78M0.6%History
EQEquillium, Inc.COM1,908,935$2.73M0.6%History
UTHRUnited Therapeutics CorpCOM6,264$2.63M0.5%History
CGONCG Oncology, Inc.COM63,019$2.54M0.5%History
Invesco QQQ Trust Series I46090E103ETF3,797$2.28M0.5%–
TNGXTango Therapeutics, Inc.COM245,378$2.06M0.4%History
ORICOric Pharmaceuticals, Inc.COM166,461$2.00M0.4%History
PEPGPepGen Inc.COM389,189$1.80M0.4%History
FRNMFreenome, Inc.CL A ORD SHS150,000$1.59M0.3%History
TARAProtara Therapeutics, Inc.COM STK363,666$1.58M0.3%History
CMPSCOMPASS Pathways plcSPONSORED ADS275,620$1.58M0.3%History
PYXSPyxis Oncology, Inc.COMMON STOCK689,538$1.53M0.3%History
DFTXDefinium Therapeutics, Inc.Stock76,875$906.4K0.2%History
ENTAEnanta Pharmaceuticals IncCOM75,194$900.1K0.2%History
ZBIOZenas BioPharma, Inc.COM38,742$860.1K0.2%History
CRVSCorvus Pharmaceuticals, Inc.COM96,439$710.8K0.1%History
KALVKalVista Pharmaceuticals, Inc.COM56,770$691.5K0.1%History
ARCTArcturus Therapeutics Holdings Inc.COM35,606$656.2K0.1%History
VTYXVentyx Biosciences, Inc.COM167,470$520.8K0.1%History
ATAIAtai Beckley N.V.SHS76,032$402.2K0.1%History