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Commodore Capital LP

SEC CIK
0001831942
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 14, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
33
+2 vs. Q1 2025
Portfolio value
$1.42B
+$59.6M (+4.4%) vs. Q1 2025
Filed
Aug 14, 2025
SEC
Holdings of Commodore Capital LP in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
MRUSMerus N.V.COM3,525,000$185.4M13.1%−947,840−21.2%ReducedHistory
NUVLNuvalent, Inc.COM1,375,000$104.9M7.4%−480,000−25.9%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM3,025,000$94.7M6.7%+700,000+30.1%AddedHistory
ELVNEnliven Therapeutics, Inc.COM4,692,809$94.1M6.6%+17,809+0.4%AddedHistory
AGIOAgios Pharmaceuticals, Inc.COM2,325,000$77.3M5.5%+140,000+6.4%AddedHistory
CLDXCelldex Therapeutics, Inc.COM NEW3,450,000$70.2M5.0%+250,000+7.8%AddedHistory
ALKSAlkermes plc.SHS2,450,000$70.1M4.9%+500,000+25.6%AddedHistory
VRDNViridian Therapeutics, Inc.COM4,875,000$68.2M4.8%+1,275,000+35.4%AddedHistory
PTGXProtagonist Therapeutics, IncCOM1,075,000$59.4M4.2%+1,075,000NewHistory
CDTXCidara Therapeutics, Inc.COM NEW1,175,000$57.2M4.0%+1,175,000NewHistory
SRRKScholar Rock Holding CorpCOM1,450,000$51.4M3.6%−295,000−16.9%ReducedHistory
SLNOSoleno Therapeutics IncCOM610,000$51.1M3.6%−540,000−47.0%ReducedHistory
RLAYRelay Therapeutics, Inc.COM13,350,000$46.2M3.3%+13,350,000NewHistory
NRIXNurix Therapeutics, Inc.COM3,948,653$45.0M3.2%−30,254−0.8%ReducedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS3,298,289$43.3M3.1%+930,711+39.3%AddedHistory
PHVSPharvaris N.V.COM1,911,433$33.6M2.4%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM750,000$32.7M2.3%+750,000NewHistory
DFTXDefinium Therapeutics, Inc.Stock5,000,000$32.5M2.3%+475,000+10.5%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW1,988,084$29.8M2.1%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM3,100,000$29.7M2.1%+2,150,000+226.3%AddedHistory
VERAVera Therapeutics, Inc.CL A800,000$18.8M1.3%−1,761,782−68.8%ReducedHistory
CTMXCytomX Therapeutics, Inc.COM7,692,300$17.5M1.2%+7,692,300NewHistory
COGTCogent Biosciences, Inc.COM2,311,164$16.6M1.2%−6,581,652−74.0%ReducedHistory
ORKAOruka Therapeutics, Inc.COM1,419,714$15.9M1.1%00.0%UnchangedHistory
DRUGBright Minds Biosciences Inc.COM NEW500,000$13.1M0.9%00.0%UnchangedHistory
APGEApogee Therapeutics, Inc.COM290,000$12.6M0.9%00.0%UnchangedHistory
IKTInhibikase Therapeutics, Inc.COM NEW5,397,488$10.5M0.7%+53,056+1.0%AddedHistory
FRNMFreenome, Inc.CL A ORD SHS750,000$7.96M0.6%00.0%UnchangedHistory
TNGXTango Therapeutics, Inc.COM1,500,000$7.68M0.5%+1,500,000NewHistory
CBIOCrescent Biopharma, Inc.COM453,686$7.32M0.5%+453,686NewHistory
NGNENeurogene Inc.COM427,866$6.40M0.5%−497,134−53.7%ReducedHistory
VTGNVistagen Therapeutics, Inc.COM1,575,000$3.15M0.2%00.0%UnchangedHistory
AVTXAvalo Therapeutics, Inc.COM NEW483,000$2.41M0.2%00.0%UnchangedHistory

Sold out since Q1 2025 (5)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of Commodore Capital LP sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
PCVXVaxcyte, Inc.COM1,650,000$62.3M4.6%History
SLDBSolid Biosciences Inc.COM NEW5,825,000$21.6M1.6%History
CRDFCardiff Oncology, Inc.COM5,384,616$16.9M1.2%History
ORICOric Pharmaceuticals, Inc.COM2,000,000$11.2M0.8%History
CELCCelcuity Inc.COM695,650$7.03M0.5%History