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Avidity Partners Management LP

SEC CIK
0001791827
Latest filing
Aug 14, 2026

Holdings in Q3 2025

Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.

Institution overview
Positions
43
−12 vs. Q2 2025
Portfolio value
$439.4M
−$59.4M (−11.9%) vs. Q2 2025
Filed
Nov 14, 2025
SEC
Holdings of Avidity Partners Management LP in Q3 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
DNTHDianthus Therapeutics, Inc.COM3,204,184$126.1M28.7%+1,461,282+83.8%AddedHistory
CGONCG Oncology, Inc.COM1,600,899$64.5M14.7%+100,957+6.7%AddedHistory
MDTMedtronic plcStock190,600$18.2M4.1%+190,600NewHistory
BSXBoston Scientific CorpStock164,300$16.0M3.7%−157,500−48.9%ReducedHistory
ORKAOruka Therapeutics, Inc.COM660,424$12.7M2.9%+308,300+87.6%AddedHistory
BMYBristol Myers Squibb CoStock257,600$11.6M2.6%+257,600NewHistory
NTRANatera, Inc.COM70,400$11.3M2.6%−128,900−64.7%ReducedHistory
DHRDanaher CorpStock54,700$10.8M2.5%−35,000−39.0%ReducedHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS510,000$10.3M2.3%−179,500−26.0%ReducedHistory
CATXPerspective Therapeutics, Inc.COM NEW2,994,033$10.3M2.3%+1,135,437+61.1%AddedHistory
JBIOJade Biosciences, Inc.COM NEW1,127,186$9.73M2.2%00.0%UnchangedHistory
PFEPfizer IncStock366,400$9.34M2.1%+366,400NewHistory
TMOThermo Fisher Scientific Inc.Stock18,900$9.17M2.1%−10,700−36.1%ReducedHistory
CNTXContext Therapeutics Inc.COM8,981,855$8.70M2.0%+1,504,600+20.1%AddedHistory
GMABGenmab A/SSPONSORED ADS248,100$7.61M1.7%−401,900−61.8%ReducedHistory
MTSRMetsera, Inc.COM140,500$7.35M1.7%+140,500NewHistory
UNHUnitedHealth Group IncStock17,800$6.15M1.4%−14,200−44.4%ReducedHistory
ARVNArvinas, Inc.COM698,363$5.95M1.4%+455,201+187.2%AddedHistory
CORCencora, Inc.Stock19,000$5.94M1.4%−13,800−42.1%ReducedHistory
EHCEncompass Health CorpCOM41,900$5.32M1.2%−32,100−43.4%ReducedHistory
JNJJohnson & JohnsonStock26,800$4.97M1.1%+26,800NewHistory
CICigna GroupStock16,600$4.78M1.1%+16,600NewHistory
ABBVAbbVie Inc.Stock19,800$4.58M1.0%+19,800NewHistory
MCKMcKesson CorpStock5,800$4.48M1.0%−7,700−57.0%ReducedHistory
CARLCarlsmed, Inc.COM321,912$4.31M1.0%+321,912NewHistory
KVUEKenvue Inc.Stock265,200$4.30M1.0%+265,200NewHistory
IMUXImmunic, Inc.COM4,699,411$4.14M0.9%−916,400−16.3%ReducedHistory
ARQTArcutis Biotherapeutics, Inc.COM214,400$4.04M0.9%−53,600−20.0%ReducedHistory
EXASExact Sciences CorpCOM73,600$4.03M0.9%−281,400−79.3%ReducedHistory
PHATPhathom Pharmaceuticals, Inc.COM306,000$3.60M0.8%−758,500−71.3%ReducedHistory
RGENRepligen CorpCOM23,300$3.11M0.7%−83,200−78.1%ReducedHistory
ACADAcadia Pharmaceuticals IncCOM144,000$3.07M0.7%+144,000NewHistory
ASNDAscendis Pharma A/SSPONSORED ADR14,500$2.88M0.7%+14,500NewHistory
ELVNEnliven Therapeutics, Inc.COM140,300$2.87M0.7%+129,000+1,141.6%AddedHistory
BEAMBeam Therapeutics Inc.COM112,000$2.72M0.6%−297,400−72.6%ReducedHistory
SCYXScynexis IncCOM NEW3,350,528$2.58M0.6%+2,121,618+172.6%AddedHistory
HQYHealthequity, Inc.COM25,300$2.40M0.5%−66,700−72.5%ReducedHistory
WVEWave Life Sciences, Inc.SHS297,500$2.18M0.5%+297,500NewHistory
XENEXenon Pharmaceuticals Inc.COM53,400$2.14M0.5%−54,491−50.5%ReducedHistory
AKROAkero Therapeutics, Inc.COM40,500$1.92M0.4%−93,500−69.8%ReducedHistory
INSMINSMED IncCOM PAR $.0111,600$1.67M0.4%−47,400−80.3%ReducedHistory
KPTIKaryopharm Therapeutics Inc.COM NEW134,566$880.1K0.2%00.0%UnchangedHistory
IMRXImmuneering CorpCLASS A COM90,900$636.3K0.1%+90,900NewHistory

Sold out since Q2 2025 (25)

Positions held at the end of Q2 2025 that are gone from this filing.

Positions of Avidity Partners Management LP sold out since Q2 2025
SecurityClassShares in Q2 2025Value in Q2 2025% of portfolio in Q2 2025History
THCTenet Healthcare CorpCOM NEW106,000$18.7M3.7%History
DXCMDexcom IncCOM210,500$18.4M3.7%History
HNGEHinge Health, Inc.CL A322,344$16.7M3.3%History
ISRGIntuitive Surgical IncCOM NEW27,100$14.7M3.0%History
AXSMAxsome Therapeutics, Inc.COM94,500$9.86M2.0%History
RVMDRevolution Medicines, Inc.COM228,600$8.41M1.7%History
OMDAOmada Health, Inc.COM390,600$7.15M1.4%History
HUMHumana IncStock27,600$6.75M1.4%History
OGNOrganon & Co.Stock640,000$6.20M1.2%History
BBIOBridgeBio Pharma, Inc.COM140,000$6.05M1.2%History
MDGLMadrigal Pharmaceuticals, Inc.COM19,000$5.75M1.2%History
RAREUltragenyx Pharmaceutical Inc.COM154,000$5.60M1.1%History
DOCSDoximity, Inc.CL A60,000$3.68M0.7%History
VRNAVerona Pharma plcSPONSORED ADS33,800$3.20M0.6%History
QUREuniQure N.V.SHS207,000$2.89M0.6%History
APGEApogee Therapeutics, Inc.COM65,000$2.82M0.6%History
SLNOSoleno Therapeutics IncCOM32,000$2.68M0.5%History
CAHCardinal Health IncStock15,000$2.52M0.5%History
SPRYARS Pharmaceuticals, Inc.COM140,000$2.44M0.5%History
KZRKezar Life Sciences, Inc.COM502,600$2.30M0.5%History
NTLAIntellia Therapeutics, Inc.COM232,000$2.18M0.4%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD39,000$1.84M0.4%History
SNDXSyndax Pharmaceuticals IncCOM150,000$1.40M0.3%History
ALTAltimmune, Inc.COM NEW105,000$406.4K0.1%History
RVPHReviva Pharmaceuticals Holdings, Inc.COM138,000$52.6K<0.1%History