Avidity Partners Management LP
- SEC CIK
- 0001791827
- Latest filing
- Aug 14, 2026
Holdings in Q4 2025
Holdings as of Dec 31, 2025, filed Feb 13, 2026. Long positions only; changes compare share counts with Q3 2025.
- Positions
- 39
- −4 vs. Q3 2025
- Portfolio value
- $346.7M
- −$92.7M (−21.1%) vs. Q3 2025
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| DNTHDianthus Therapeutics, Inc. | COM | 2,104,184 | $86.7M | 25.0% | −1,100,000−34.3% | Reduced | History |
| CGONCG Oncology, Inc. | COM | 1,472,699 | $61.1M | 17.6% | −128,200−8.0% | Reduced | History |
| JBIOJade Biosciences, Inc. | COM NEW | 1,400,708 | $21.6M | 6.2% | +273,522+24.3% | Added | History |
| ORKAOruka Therapeutics, Inc. | COM | 660,424 | $20.0M | 5.8% | 00.0% | Unchanged | History |
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | 417,300 | $13.0M | 3.8% | −92,700−18.2% | Reduced | History |
| BSXBoston Scientific Corp | Stock | 114,500 | $10.9M | 3.1% | −49,800−30.3% | Reduced | History |
| MDTMedtronic plc | Stock | 107,600 | $10.3M | 3.0% | −83,000−43.5% | Reduced | History |
| CATXPerspective Therapeutics, Inc. | COM NEW | 3,210,733 | $8.83M | 2.5% | +216,700+7.2% | Added | History |
| ALNYAlnylam Pharmaceuticals, Inc. | COM | 21,000 | $8.35M | 2.4% | +21,000 | New | History |
| RGENRepligen Corp | COM | 50,300 | $8.24M | 2.4% | +27,000+115.9% | Added | History |
| CNTXContext Therapeutics Inc. | COM | 5,504,855 | $8.09M | 2.3% | −3,477,000−38.7% | Reduced | History |
| MCKMcKesson Corp | Stock | 9,520 | $7.81M | 2.3% | +3,720+64.1% | Added | History |
| ICLRIcon PLC | COM | 33,100 | $6.03M | 1.7% | +33,100 | New | History |
| AAgilent Technologies, Inc. | COM | 41,500 | $5.65M | 1.6% | +41,500 | New | History |
| PFEPfizer Inc | Stock | 203,600 | $5.07M | 1.5% | −162,800−44.4% | Reduced | History |
| CNCCentene Corp | Stock | 119,400 | $4.91M | 1.4% | +119,400 | New | History |
| KVUEKenvue Inc. | Stock | 232,800 | $4.02M | 1.2% | −32,400−12.2% | Reduced | History |
| DHRDanaher Corp | Stock | 17,000 | $3.89M | 1.1% | −37,700−68.9% | Reduced | History |
| TMOThermo Fisher Scientific Inc. | Stock | 6,700 | $3.88M | 1.1% | −12,200−64.6% | Reduced | History |
| NVONovo Nordisk A S | ADR | 67,300 | $3.42M | 1.0% | +67,300 | New | History |
| PHATPhathom Pharmaceuticals, Inc. | COM | 206,076 | $3.42M | 1.0% | −99,924−32.7% | Reduced | History |
| EHCEncompass Health Corp | COM | 31,600 | $3.35M | 1.0% | −10,300−24.6% | Reduced | History |
| CICigna Group | Stock | 11,600 | $3.19M | 0.9% | −5,000−30.1% | Reduced | History |
| CORCencora, Inc. | Stock | 9,400 | $3.17M | 0.9% | −9,600−50.5% | Reduced | History |
| INSMINSMED Inc | COM PAR $.01 | 17,700 | $3.08M | 0.9% | +6,100+52.6% | Added | History |
| WATWaters Corp | COM | 8,100 | $3.08M | 0.9% | +8,100 | New | History |
| ACADAcadia Pharmaceuticals Inc | COM | 106,900 | $2.86M | 0.8% | −37,100−25.8% | Reduced | History |
| GMABGenmab A/S | SPONSORED ADS | 92,000 | $2.83M | 0.8% | −156,100−62.9% | Reduced | History |
| NTRANatera, Inc. | COM | 11,800 | $2.70M | 0.8% | −58,600−83.2% | Reduced | History |
| IMUXImmunic, Inc. | COM | 4,699,411 | $2.51M | 0.7% | 00.0% | Unchanged | History |
| ACHCAcadia Healthcare Company, Inc. | COM | 169,000 | $2.40M | 0.7% | +169,000 | New | History |
| ITGRInteger Holdings Corp | COM | 29,800 | $2.34M | 0.7% | +29,800 | New | History |
| ELVNEnliven Therapeutics, Inc. | COM | 140,300 | $2.16M | 0.6% | 00.0% | Unchanged | History |
| PVLAPalvella Therapeutics, Inc. | COM | 19,300 | $2.02M | 0.6% | +19,300 | New | History |
| HQYHealthequity, Inc. | COM | 16,900 | $1.55M | 0.4% | −8,400−33.2% | Reduced | History |
| SCYXScynexis Inc | COM NEW | 2,081,660 | $1.32M | 0.4% | −1,268,868−37.9% | Reduced | History |
| IQVIQVIA Holdings Inc. | Stock | 4,400 | $991.8K | 0.3% | +4,400 | New | History |
| KPTIKaryopharm Therapeutics Inc. | COM NEW | 134,566 | $990.4K | 0.3% | 00.0% | Unchanged | History |
| CORTCorcept Therapeutics Inc | COM | 22,000 | $765.6K | 0.2% | +22,000 | New | History |
Sold out since Q3 2025 (15)
Positions held at the end of Q3 2025 that are gone from this filing.
| Security | Class | Shares in Q3 2025 | Value in Q3 2025 | % of portfolio in Q3 2025 | History |
|---|---|---|---|---|---|
| BMYBristol Myers Squibb Co | Stock | 257,600 | $11.6M | 2.6% | History |
| MTSRMetsera, Inc. | COM | 140,500 | $7.35M | 1.7% | History |
| UNHUnitedHealth Group Inc | Stock | 17,800 | $6.15M | 1.4% | History |
| ARVNArvinas, Inc. | COM | 698,363 | $5.95M | 1.4% | History |
| JNJJohnson & Johnson | Stock | 26,800 | $4.97M | 1.1% | History |
| ABBVAbbVie Inc. | Stock | 19,800 | $4.58M | 1.0% | History |
| CARLCarlsmed, Inc. | COM | 321,912 | $4.31M | 1.0% | History |
| ARQTArcutis Biotherapeutics, Inc. | COM | 214,400 | $4.04M | 0.9% | History |
| EXASExact Sciences Corp | COM | 73,600 | $4.03M | 0.9% | History |
| ASNDAscendis Pharma A/S | SPONSORED ADR | 14,500 | $2.88M | 0.7% | History |
| BEAMBeam Therapeutics Inc. | COM | 112,000 | $2.72M | 0.6% | History |
| WVEWave Life Sciences, Inc. | SHS | 297,500 | $2.18M | 0.5% | History |
| XENEXenon Pharmaceuticals Inc. | COM | 53,400 | $2.14M | 0.5% | History |
| AKROAkero Therapeutics, Inc. | COM | 40,500 | $1.92M | 0.4% | History |
| IMRXImmuneering Corp | CLASS A COM | 90,900 | $636.3K | 0.1% | History |