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Avidity Partners Management LP

SEC CIK
0001791827
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 14, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
55
−8 vs. Q1 2025
Portfolio value
$498.8M
+$13.9M (+2.9%) vs. Q1 2025
Filed
Aug 14, 2025
SEC
Holdings of Avidity Partners Management LP in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
CGONCG Oncology, Inc.COM1,499,942$39.0M7.8%+519,000+52.9%AddedHistory
BSXBoston Scientific CorpStock321,800$34.6M6.9%−14,200−4.2%ReducedHistory
NTRANatera, Inc.COM199,300$33.7M6.8%+80,100+67.2%AddedHistory
DNTHDianthus Therapeutics, Inc.COM1,742,902$32.5M6.5%+22,000+1.3%AddedHistory
EXASExact Sciences CorpCOM355,000$18.9M3.8%+2,000+0.6%AddedHistory
THCTenet Healthcare CorpCOM NEW106,000$18.7M3.7%+34,000+47.2%AddedHistory
DXCMDexcom IncCOM210,500$18.4M3.7%+30,500+16.9%AddedHistory
DHRDanaher CorpStock89,700$17.7M3.6%+45,200+101.6%AddedHistory
HNGEHinge Health, Inc.CL A322,344$16.7M3.3%+322,344NewHistory
ISRGIntuitive Surgical IncCOM NEW27,100$14.7M3.0%+27,100NewHistory
GMABGenmab A/SSPONSORED ADS650,000$13.4M2.7%+650,000NewHistory
RGENRepligen CorpCOM106,500$13.2M2.7%+106,500NewHistory
TMOThermo Fisher Scientific Inc.Stock29,600$12.0M2.4%+14,100+91.0%AddedHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS689,500$11.6M2.3%+208,500+43.3%AddedHistory
JBIOJade Biosciences, Inc.COM NEW1,127,186$11.3M2.3%+1,127,186NewHistory
PHATPhathom Pharmaceuticals, Inc.COM1,064,500$10.2M2.0%+264,500+33.1%AddedHistory
UNHUnitedHealth Group IncStock32,000$9.98M2.0%−18,500−36.6%ReducedHistory
MCKMcKesson CorpStock13,500$9.89M2.0%+13,500NewHistory
AXSMAxsome Therapeutics, Inc.COM94,500$9.86M2.0%+17,500+22.7%AddedHistory
CORCencora, Inc.Stock32,800$9.84M2.0%−6,500−16.5%ReducedHistory
HQYHealthequity, Inc.COM92,000$9.64M1.9%+14,000+17.9%AddedHistory
EHCEncompass Health CorpCOM74,000$9.07M1.8%+74,000NewHistory
RVMDRevolution Medicines, Inc.COM228,600$8.41M1.7%+15,600+7.3%AddedHistory
AKROAkero Therapeutics, Inc.COM134,000$7.15M1.4%+77,000+135.1%AddedHistory
OMDAOmada Health, Inc.COM390,600$7.15M1.4%+390,600NewHistory
BEAMBeam Therapeutics Inc.COM409,400$6.96M1.4%−300,117−42.3%ReducedHistory
HUMHumana IncStock27,600$6.75M1.4%−53,400−65.9%ReducedHistory
CATXPerspective Therapeutics, Inc.COM NEW1,858,596$6.39M1.3%−338,674−15.4%ReducedHistory
OGNOrganon & Co.Stock640,000$6.20M1.2%+105,000+19.6%AddedHistory
BBIOBridgeBio Pharma, Inc.COM140,000$6.05M1.2%+65,000+86.7%AddedHistory
INSMINSMED IncCOM PAR $.0159,000$5.94M1.2%−48,000−44.9%ReducedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM19,000$5.75M1.2%+19,000NewHistory
RAREUltragenyx Pharmaceutical Inc.COM154,000$5.60M1.1%−168,100−52.2%ReducedHistory
CNTXContext Therapeutics Inc.COM7,477,255$4.90M1.0%+550.0%AddedHistory
ORKAOruka Therapeutics, Inc.COM352,124$3.95M0.8%00.0%UnchangedHistory
IMUXImmunic, Inc.COM5,615,811$3.92M0.8%+1,161,403+26.1%AddedHistory
ARQTArcutis Biotherapeutics, Inc.COM268,000$3.76M0.8%+268,000NewHistory
DOCSDoximity, Inc.CL A60,000$3.68M0.7%−62,500−51.0%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM107,891$3.38M0.7%−121,109−52.9%ReducedHistory
VRNAVerona Pharma plcSPONSORED ADS33,800$3.20M0.6%+33,800NewHistory
QUREuniQure N.V.SHS207,000$2.89M0.6%−129,200−38.4%ReducedHistory
APGEApogee Therapeutics, Inc.COM65,000$2.82M0.6%+65,000NewHistory
SLNOSoleno Therapeutics IncCOM32,000$2.68M0.5%00.0%UnchangedHistory
CAHCardinal Health IncStock15,000$2.52M0.5%+15,000NewHistory
SPRYARS Pharmaceuticals, Inc.COM140,000$2.44M0.5%+140,000NewHistory
KZRKezar Life Sciences, Inc.COM502,600$2.30M0.5%00.0%UnchangedHistory
NTLAIntellia Therapeutics, Inc.COM232,000$2.18M0.4%+232,000NewHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD39,000$1.84M0.4%+39,000NewHistory
ARVNArvinas, Inc.COM243,162$1.79M0.4%−170,000−41.1%ReducedHistory
SNDXSyndax Pharmaceuticals IncCOM150,000$1.40M0.3%−775,000−83.8%ReducedHistory
SCYXScynexis IncCOM NEW1,228,910$829.3K0.2%00.0%UnchangedHistory
KPTIKaryopharm Therapeutics Inc.COM NEW134,566$580.0K0.1%00.0%UnchangedHistory
ALTAltimmune, Inc.COM NEW105,000$406.4K0.1%+105,000NewHistory
ELVNEnliven Therapeutics, Inc.COM11,300$226.7K<0.1%00.0%UnchangedHistory
RVPHReviva Pharmaceuticals Holdings, Inc.COM138,000$52.6K<0.1%00.0%UnchangedHistory

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Avidity Partners Management LP in Q2 2025
SecurityClassPutsCalls
SNDXSyndax Pharmaceuticals IncCOM–$3.18M

Sold out since Q1 2025 (25)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of Avidity Partners Management LP sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
REGNRegeneron Pharmaceuticals, Inc.COM25,400$16.1M3.3%History
GKOSGLAUKOS CorpCOM134,000$13.2M2.7%History
JAZZJazz Pharmaceuticals plcSHS USD80,000$9.93M2.0%History
NBIXNeurocrine Biosciences IncStock85,700$9.48M2.0%History
State Street SPDR S&P Biotech ETF78464A870ETF94,000$7.62M1.6%–
CNTACentessa Pharmaceuticals plcSPONSORED ADS529,000$7.61M1.6%History
AVTRAvantor, Inc.COM453,000$7.34M1.5%History
IDYAIDEAYA Biosciences, Inc.COM445,000$7.29M1.5%History
JANXJanux Therapeutics, Inc.COM258,000$6.97M1.4%History
BPMCBlueprint Medicines CorpCOM68,500$6.06M1.3%History
UTHRUnited Therapeutics CorpCOM16,800$5.18M1.1%History
BRKRBruker CorpCOM115,000$4.80M1.0%History
BHVNBiohaven Ltd.COM145,000$3.49M0.7%History
ACADAcadia Pharmaceuticals IncCOM169,000$2.81M0.6%History
RPRXRoyalty Pharma plcSHS CLASS A87,000$2.71M0.6%History
CAPRCapricor Therapeutics, Inc.COM NEW239,000$2.27M0.5%History
LXEOLexeo Therapeutics, Inc.COM645,000$2.24M0.5%History
VERAVera Therapeutics, Inc.CL A91,000$2.19M0.5%History
RGNXREGENXBIO Inc.COM260,000$1.86M0.4%History
IONSIonis Pharmaceuticals IncCOM60,000$1.81M0.4%History
MIRMMirum Pharmaceuticals, Inc.COM40,000$1.80M0.4%History
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES68,000$1.39M0.3%History
AGLagilon health, inc.COM305,100$1.32M0.3%History
PCVXVaxcyte, Inc.COM23,000$868.5K0.2%History
HYPRHyperfine, Inc.COM CL A222,174$159.1K<0.1%History