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Avidity Partners Management LP

SEC CIK
0001791827
Latest filing
Aug 14, 2026

Holdings in Q1 2024

Holdings as of Mar 31, 2024, filed May 15, 2024. Long positions only; changes compare share counts with Q4 2023.

Institution overview
Positions
87
+15 vs. Q4 2023
Portfolio value
$2.81B
+$198.8M (+7.6%) vs. Q4 2023
Filed
May 15, 2024
SEC
Holdings of Avidity Partners Management LP in Q1 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
FUSNFusion Pharmaceuticals Inc.COM6,500,328$138.6M4.9%00.0%UnchangedHistory
BSXBoston Scientific CorpStock1,956,000$134.0M4.8%+66,000+3.5%AddedHistory
ARVNArvinas, Inc.COM2,985,190$123.2M4.4%+730.0%AddedHistory
ISRGIntuitive Surgical IncCOM NEW226,000$90.2M3.2%+141,000+165.9%AddedHistory
DNTHDianthus Therapeutics, Inc.COM2,717,554$81.5M2.9%+1,500,000+123.2%AddedHistory
ACHCAcadia Healthcare Company, Inc.COM1,005,000$79.6M2.8%−151,692−13.1%ReducedHistory
NBIXNeurocrine Biosciences IncStock536,500$74.0M2.6%−121,500−18.5%ReducedHistory
NTRANatera, Inc.COM803,300$73.5M2.6%−306,700−27.6%ReducedHistory
JAZZJazz Pharmaceuticals plcSHS USD584,000$70.3M2.5%+94,881+19.4%AddedHistory
AVTRAvantor, Inc.COM2,695,000$68.9M2.4%+573,156+27.0%AddedHistory
CICigna GroupStock184,500$67.0M2.4%+184,500NewHistory
MRKMerck & Co., Inc.Stock502,000$66.2M2.4%+502,000NewHistory
REGNRegeneron Pharmaceuticals, Inc.COM68,000$65.4M2.3%00.0%UnchangedHistory
CGONCG Oncology, Inc.COM1,454,765$63.9M2.3%+1,454,765NewHistory
ILMNIllumina, Inc.COM464,100$63.7M2.3%+464,100NewHistory
THCTenet Healthcare CorpCOM NEW601,000$63.2M2.2%−270,000−31.0%ReducedHistory
ALGNAlign Technology IncCOM189,000$62.0M2.2%+33,200+21.3%AddedHistory
SNDXSyndax Pharmaceuticals IncCOM2,412,500$57.4M2.0%−1,537,500−38.9%ReducedHistory
LLYEli Lilly & CoStock70,000$54.5M1.9%−15,000−17.6%ReducedHistory
UTHRUnited Therapeutics CorpCOM217,000$49.8M1.8%−20,202−8.5%ReducedHistory
ALPNAlpine Immune Sciences, Inc.COM1,174,700$46.6M1.7%+1,174,700NewHistory
RAREUltragenyx Pharmaceutical Inc.COM933,500$43.6M1.5%+89,000+10.5%AddedHistory
CVSCVS Health CorpStock545,000$43.5M1.5%−195,000−26.4%ReducedHistory
SGRYSurgery Partners, Inc.Stock1,445,000$43.1M1.5%+279,068+23.9%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM600,000$41.5M1.5%−110,000−15.5%ReducedHistory
ABBVAbbVie Inc.Stock227,000$41.3M1.5%−57,405−20.2%ReducedHistory
BPMCBlueprint Medicines CorpCOM426,000$40.4M1.4%−189,000−30.7%ReducedHistory
LEGNLegend Biotech CorpSPONSORED ADS668,300$37.5M1.3%−16,700−2.4%ReducedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS864,000$37.0M1.3%−216,000−20.0%ReducedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM243,000$36.3M1.3%+243,000NewHistory
DHRDanaher CorpStock143,800$35.9M1.3%−146,200−50.4%ReducedHistory
IDYAIDEAYA Biosciences, Inc.COM799,700$35.1M1.2%−720,300−47.4%ReducedHistory
AXSMAxsome Therapeutics, Inc.COM431,000$34.4M1.2%−28,400−6.2%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM710,000$30.6M1.1%−105,993−13.0%ReducedHistory
LNTHLantheus Holdings, Inc.Stock480,000$29.9M1.1%+100,000+26.3%AddedHistory
CRBUCaribou Biosciences, Inc.COM5,785,352$29.7M1.1%−574,860−9.0%ReducedHistory
MIRMMirum Pharmaceuticals, Inc.COM1,142,850$28.7M1.0%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,025,000$27.6M1.0%−694,103−40.4%ReducedHistory
RGNXREGENXBIO Inc.COM1,300,064$27.4M1.0%+1,300,064NewHistory
APGEApogee Therapeutics, Inc.COM384,893$25.6M0.9%+384,893NewHistory
NMRANeumora Therapeutics, Inc.COM1,800,000$24.8M0.9%−190,632−9.6%ReducedHistory
DXCMDexcom IncCOM176,900$24.5M0.9%+176,900NewHistory
NGNENeurogene Inc.COM465,237$23.7M0.8%−1,006−0.2%ReducedHistory
JSPRJasper Therapeutics, Inc.COM NEW760,000$22.3M0.8%+760,000NewHistory
IMNMImmunome Inc.COM873,891$21.6M0.8%−459,588−34.5%ReducedHistory
TMOThermo Fisher Scientific Inc.Stock36,600$21.3M0.8%−146,000−80.0%ReducedHistory
GKOSGLAUKOS CorpCOM224,000$21.1M0.8%+224,000NewHistory
RVMDRevolution Medicines, Inc.COM635,000$20.5M0.7%+575,000+958.3%AddedHistory
PCVXVaxcyte, Inc.COM284,000$19.4M0.7%−286,137−50.2%ReducedHistory
IMCRImmunocore Holdings plcADS286,400$18.6M0.7%−13,800−4.6%ReducedHistory
PHATPhathom Pharmaceuticals, Inc.COM1,735,000$18.4M0.7%+13,420+0.8%AddedHistory
MCKMcKesson CorpStock33,300$17.9M0.6%−52,200−61.1%ReducedHistory
VERAVera Therapeutics, Inc.CL A383,500$16.5M0.6%+383,500NewHistory
IMVTImmunovant, Inc.COM505,000$16.3M0.6%+260,000+106.1%AddedHistory
PRVAPrivia Health Group, Inc.COM764,200$15.0M0.5%−522,800−40.6%ReducedHistory
JANXJanux Therapeutics, Inc.COM384,245$14.5M0.5%+384,245NewHistory
Cybin Ord23256X100COM34,884,000$14.4M0.5%+34,884,000New–
COLLCollegium Pharmaceutical, IncCOM361,400$14.0M0.5%+370.0%AddedHistory
PRMEPrime Medicine, Inc.COM1,990,000$13.9M0.5%+1,990,000NewHistory
KROSKeros Therapeutics, Inc.COM209,700$13.9M0.5%+209,700NewHistory
ATXSAstria Therapeutics, Inc.COM982,000$13.8M0.5%+982,000NewHistory
ACIUAC Immune SASHS4,470,000$13.2M0.5%+9200.0%AddedHistory
KPTIKaryopharm Therapeutics Inc.COM8,298,570$12.5M0.4%00.0%UnchangedHistory
IMUXImmunic, Inc.COM8,902,972$11.8M0.4%+8,902,972NewHistory
CYTKCytokinetics IncCOM NEW166,000$11.6M0.4%+166,000NewHistory
RDNTRadNet, Inc.COM238,000$11.6M0.4%+238,000NewHistory
ESTAEstablishment Labs Holdings Inc.COM225,000$11.5M0.4%+225,000NewHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES475,000$11.2M0.4%+475,000NewHistory
ACADAcadia Pharmaceuticals IncCOM588,500$10.9M0.4%+588,500NewHistory
AZNAstraZeneca PLCSPONSORED ADR160,000$10.8M0.4%+160,000NewHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW1,673,538$8.95M0.3%00.0%UnchangedHistory
IONSIonis Pharmaceuticals IncCOM130,000$5.64M0.2%+130,000NewHistory
IPSCCentury Therapeutics, Inc.COM1,221,555$5.11M0.2%−133,445−9.8%ReducedHistory
KYTXKyverna Therapeutics, Inc.COM202,333$5.03M0.2%+202,333NewHistory
EBSEmergent BioSolutions Inc.COM1,908,000$4.83M0.2%+1,908,000NewHistory
KZRKezar Life Sciences, Inc.COM5,026,000$4.53M0.2%+5460.0%AddedHistory
BHVNBiohaven Ltd.COM75,000$4.10M0.1%−1,073,308−93.5%ReducedHistory
ANTXAN2 Therapeutics, Inc.COM1,150,000$3.74M0.1%+10,000+0.9%AddedHistory
DNAGinkgo Bioworks Holdings, Inc.CL A SHS3,000,000$3.48M0.1%+3,000,000NewHistory
XFORX4 Pharmaceuticals, IncCOM2,413,000$3.35M0.1%+2,413,000NewHistory
COGTCogent Biosciences, Inc.COM445,706$3.00M0.1%+445,706NewHistory
PACBPacific Biosciences of California, Inc.COM675,000$2.53M0.1%+675,000NewHistory
SCYXScynexis IncCOM NEW1,448,728$2.13M0.1%00.0%UnchangedHistory
KODKodiak Sciences Inc.COM300,000$1.58M0.1%+300,000NewHistory
HYPRHyperfine, Inc.COM CL A1,188,178$1.19M<0.1%00.0%UnchangedHistory
CMAXCareMax, Inc.COMM STK21,200$102.2K<0.1%00.0%UnchangedConverted for a 1-for-30 splitHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/20289,543$27.1K<0.1%00.0%Unchanged–

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Avidity Partners Management LP in Q1 2024
SecurityClassPutsCalls
ITCIIntra-Cellular Therapies, Inc.COM–$239.5M
CYTKCytokinetics IncCOM NEW–$42.1M
GPCRStructure Therapeutics Inc.SPONSORED ADS–$6.43M

Sold out since Q4 2023 (17)

Positions held at the end of Q4 2023 that are gone from this filing.

Positions of Avidity Partners Management LP sold out since Q4 2023
SecurityClassShares in Q4 2023Value in Q4 2023% of portfolio in Q4 2023History
KRTXKaruna Therapeutics, Inc.COM206,000$65.2M2.5%History
IMGNImmunoGen, Inc.COM1,829,215$54.2M2.1%History
ZTSZoetis Inc.Stock240,000$47.4M1.8%History
HUMHumana IncStock100,000$45.8M1.8%History
BDXBecton Dickinson & CoStock165,706$40.4M1.5%History
UNHUnitedHealth Group IncStock58,500$30.8M1.2%History
ARWRArrowhead Pharmaceuticals, Inc.COM714,000$21.8M0.8%History
CRNXCrinetics Pharmaceuticals, Inc.COM529,000$18.8M0.7%History
VRNAVerona Pharma plcSPONSORED ADS780,900$15.5M0.6%History
AAgilent Technologies, Inc.COM99,000$13.8M0.5%History
NTLAIntellia Therapeutics, Inc.COM447,434$13.6M0.5%History
ARGXArgenx SESPONSORED ADR31,000$11.8M0.5%History
CERECerevel Therapeutics Holdings, Inc.COM276,888$11.7M0.4%History
TVTXTravere Therapeutics, Inc.COM827,010$7.43M0.3%History
AKROAkero Therapeutics, Inc.COM235,000$5.49M0.2%History
CMPXCompass Therapeutics, Inc.COM1,599,600$2.50M0.1%History
AMLXAmylyx Pharmaceuticals, Inc.COM64,501$949.5K<0.1%History