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Avidity Partners Management LP

SEC CIK
0001791827
Latest filing
Aug 14, 2026

Holdings in Q4 2023

Holdings as of Dec 31, 2023, filed Feb 14, 2024. Long positions only; changes compare share counts with Q3 2023.

Institution overview
Positions
72
−11 vs. Q3 2023
Portfolio value
$2.61B
+$131.5M (+5.3%) vs. Q3 2023
Filed
Feb 14, 2024
SEC
Holdings of Avidity Partners Management LP in Q4 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
ARVNArvinas, Inc.COM2,985,117$122.9M4.7%+370,157+14.2%AddedHistory
BSXBoston Scientific CorpStock1,890,000$109.3M4.2%−175,800−8.5%ReducedHistory
TMOThermo Fisher Scientific Inc.Stock182,600$96.9M3.7%+182,600NewHistory
ACHCAcadia Healthcare Company, Inc.COM1,156,692$89.9M3.4%+441,692+61.8%AddedHistory
NBIXNeurocrine Biosciences IncStock658,000$86.7M3.3%+5,900+0.9%AddedHistory
SNDXSyndax Pharmaceuticals IncCOM3,950,000$85.4M3.3%+1,129,000+40.0%AddedHistory
NTRANatera, Inc.COM1,110,000$69.5M2.7%+211,000+23.5%AddedHistory
DHRDanaher CorpStock290,000$67.1M2.6%+113,400+64.2%AddedHistory
THCTenet Healthcare CorpCOM NEW871,000$65.8M2.5%−92,800−9.6%ReducedHistory
KRTXKaruna Therapeutics, Inc.COM206,000$65.2M2.5%−80,700−28.1%ReducedHistory
FUSNFusion Pharmaceuticals Inc.COM6,500,328$62.5M2.4%+718,478+12.4%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD489,119$60.2M2.3%−308,381−38.7%ReducedHistory
REGNRegeneron Pharmaceuticals, Inc.COM68,000$59.7M2.3%+10,000+17.2%AddedHistory
CVSCVS Health CorpStock740,000$58.4M2.2%+740,000NewHistory
BPMCBlueprint Medicines CorpCOM615,000$56.7M2.2%−136,600−18.2%ReducedHistory
IMGNImmunoGen, Inc.COM1,829,215$54.2M2.1%−88,692−4.6%ReducedHistory
IDYAIDEAYA Biosciences, Inc.COM1,520,000$54.1M2.1%−624,971−29.1%ReducedHistory
UTHRUnited Therapeutics CorpCOM237,202$52.2M2.0%+237,202NewHistory
RCKTRocket Pharmaceuticals, Inc.COM1,719,103$51.5M2.0%+131,674+8.3%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM710,000$50.9M1.9%−91,100−11.4%ReducedHistory
LLYEli Lilly & CoStock85,000$49.5M1.9%+10,000+13.3%AddedHistory
BHVNBiohaven Ltd.COM1,148,308$49.1M1.9%−137,092−10.7%ReducedHistory
AVTRAvantor, Inc.COM2,121,844$48.4M1.9%+2,121,844NewHistory
ZTSZoetis Inc.Stock240,000$47.4M1.8%−22,100−8.4%ReducedHistory
HUMHumana IncStock100,000$45.8M1.8%−10,300−9.3%ReducedHistory
ABBVAbbVie Inc.Stock284,405$44.1M1.7%+284,405NewHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS1,080,000$44.0M1.7%+580,000+116.0%AddedHistory
ALGNAlign Technology IncCOM155,800$42.7M1.6%+155,800NewHistory
LEGNLegend Biotech CorpSPONSORED ADS685,000$41.2M1.6%−282,000−29.2%ReducedHistory
BDXBecton Dickinson & CoStock165,706$40.4M1.5%−121,094−42.2%ReducedHistory
RAREUltragenyx Pharmaceutical Inc.COM844,500$40.4M1.5%+300,500+55.2%AddedHistory
MCKMcKesson CorpStock85,500$39.6M1.5%−80,800−48.6%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM815,993$37.6M1.4%+494,593+153.9%AddedHistory
SGRYSurgery Partners, Inc.Stock1,165,932$37.3M1.4%−172,068−12.9%ReducedHistory
AXSMAxsome Therapeutics, Inc.COM459,400$36.6M1.4%+162,600+54.8%AddedHistory
CRBUCaribou Biosciences, Inc.COM6,360,212$36.4M1.4%+310,000+5.1%AddedHistory
PCVXVaxcyte, Inc.COM570,137$35.8M1.4%−186,028−24.6%ReducedHistory
NMRANeumora Therapeutics, Inc.COM1,990,632$33.9M1.3%+190,632+10.6%AddedHistory
MIRMMirum Pharmaceuticals, Inc.COM1,142,850$33.7M1.3%00.0%UnchangedHistory
UNHUnitedHealth Group IncStock58,500$30.8M1.2%−53,700−47.9%ReducedHistory
PRVAPrivia Health Group, Inc.COM1,287,000$29.6M1.1%−258,100−16.7%ReducedHistory
ISRGIntuitive Surgical IncCOM NEW85,000$28.7M1.1%+85,000NewHistory
LNTHLantheus Holdings, Inc.Stock380,000$23.6M0.9%−178,400−31.9%ReducedHistory
ANTXAN2 Therapeutics, Inc.COM1,140,000$23.4M0.9%+50,600+4.6%AddedHistory
ACIUAC Immune SASHS4,469,080$22.3M0.9%+1,499,280+50.5%AddedHistory
ARWRArrowhead Pharmaceuticals, Inc.COM714,000$21.8M0.8%−349,897−32.9%ReducedHistory
IMCRImmunocore Holdings plcADS300,200$20.5M0.8%−48,000−13.8%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM529,000$18.8M0.7%−81,000−13.3%ReducedHistory
PHATPhathom Pharmaceuticals, Inc.COM1,721,580$15.7M0.6%+104,280+6.4%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS780,900$15.5M0.6%−49,400−5.9%ReducedHistory
IMNMImmunome Inc.COM1,333,479$14.3M0.5%+1,333,479NewHistory
AAgilent Technologies, Inc.COM99,000$13.8M0.5%+99,000NewHistory
NTLAIntellia Therapeutics, Inc.COM447,434$13.6M0.5%+68,334+18.0%AddedHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW1,673,538$13.0M0.5%+92,396+5.8%AddedHistory
DNTHDianthus Therapeutics, Inc.COM1,217,554$12.7M0.5%00.0%UnchangedHistory
ARGXArgenx SESPONSORED ADR31,000$11.8M0.5%−49,600−61.5%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM276,888$11.7M0.4%−366,112−56.9%ReducedHistory
COLLCollegium Pharmaceutical, IncCOM361,363$11.1M0.4%+11,163+3.2%AddedHistory
IMVTImmunovant, Inc.COM245,000$10.3M0.4%−928,662−79.1%ReducedHistory
NGNENeurogene Inc.COM466,243$9.04M0.3%+466,243NewHistory
TVTXTravere Therapeutics, Inc.COM827,010$7.43M0.3%−495,990−37.5%ReducedHistory
KPTIKaryopharm Therapeutics Inc.COM8,298,570$7.18M0.3%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM235,000$5.49M0.2%−504,100−68.2%ReducedHistory
KZRKezar Life Sciences, Inc.COM5,025,454$4.76M0.2%−985,646−16.4%ReducedHistory
IPSCCentury Therapeutics, Inc.COM1,355,000$4.50M0.2%+256,500+23.4%AddedHistory
SCYXScynexis IncCOM NEW1,448,728$3.23M0.1%+129,284+9.8%AddedHistory
CMPXCompass Therapeutics, Inc.COM1,599,600$2.50M0.1%00.0%UnchangedHistory
RVMDRevolution Medicines, Inc.COM60,000$1.72M0.1%−597,200−90.9%ReducedHistory
HYPRHyperfine, Inc.COM CL A1,188,178$1.33M0.1%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM64,501$949.5K<0.1%−1,692,439−96.3%ReducedHistory
CMAXCareMax, Inc.COM CL A636,000$316.9K<0.1%00.0%UnchangedHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/20289,543$5.37K<0.1%00.0%Unchanged–

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Avidity Partners Management LP in Q4 2023
SecurityClassPutsCalls
CICigna GroupStock–$104.8M
GPCRStructure Therapeutics Inc.SPONSORED ADS–$24.5M

Sold out since Q3 2023 (21)

Positions held at the end of Q3 2023 that are gone from this filing.

Positions of Avidity Partners Management LP sold out since Q3 2023
SecurityClassShares in Q3 2023Value in Q3 2023% of portfolio in Q3 2023History
CICigna GroupStock207,700$59.4M2.4%History
SRPTSarepta Therapeutics, Inc.COM450,000$54.5M2.2%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD777,172$44.3M1.8%History
ZNTLZentalis Pharmaceuticals, Inc.COM2,100,000$42.1M1.7%History
DXCMDexcom IncCOM377,700$35.2M1.4%History
BIIBBiogen Inc.COM115,400$29.7M1.2%History
HCAHCA Healthcare, Inc.COM114,800$28.2M1.1%History
UHSUniversal Health Services IncCL B182,000$22.9M0.9%History
Curevac N VN2451R105COM3,116,100$21.3M0.9%–
PRTAProthena Corp Public Ltd CoSHS382,305$18.4M0.7%History
ROIVRoivant Sciences Ltd.SHS1,503,302$17.6M0.7%History
VTYXVentyx Biosciences, Inc.COM354,900$12.3M0.5%History
SDGRSchrodinger, Inc.COM399,000$11.3M0.5%History
RYZBRayzeBio, Inc.COM500,000$11.1M0.4%History
PACBPacific Biosciences of California, Inc.COM1,034,294$8.64M0.3%History
ALPNAlpine Immune Sciences, Inc.COM657,280$7.53M0.3%History
GRTSGritstone bio, Inc.COM2,733,800$4.70M0.2%History
ATECAlphatec Holdings, Inc.COM NEW309,400$4.01M0.2%History
NSTGNS Wind Down Co., Inc.COM2,299,100$3.95M0.2%History
VERVVerve Therapeutics, Inc.COM285,334$3.78M0.2%History
ALTAltimmune, Inc.COM NEW1,159,900$3.02M0.1%History