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Affinity Asset Advisors, LLC

SEC CIK
0001773195
Latest filing
Aug 13, 2026

Holdings in Q2 2026

Holdings as of Jun 30, 2026, filed Aug 13, 2026. Long positions only; changes compare share counts with Q1 2026.

Institution overview
Positions
104
+9 vs. Q1 2026
Portfolio value
$2.04B
+$339.7M (+19.9%) vs. Q1 2026
Filed
Aug 13, 2026
SEC
Holdings of Affinity Asset Advisors, LLC in Q2 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
ROIVRoivant Sciences Ltd.SHS3,750,000$132.7M6.5%+950,000+33.9%AddedHistory
APGEApogee Therapeutics, Inc.COM987,000$131.0M6.4%−297,926−23.2%ReducedHistory
SYRESpyre Therapeutics, Inc.COM NEW1,279,134$113.6M5.6%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM1,595,000$96.3M4.7%−80,000−4.8%ReducedHistory
ERASErasca, Inc.COM5,250,000$96.2M4.7%−100,000−1.9%ReducedHistory
INSMINSMED IncCOM PAR $.01650,000$69.3M3.4%+170,000+35.4%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW185,000$61.9M3.0%+15,000+8.8%AddedHistory
ALKSAlkermes plc.SHS1,125,000$58.9M2.9%−225,000−16.7%ReducedHistory
ORKAOruka Therapeutics, Inc.COM590,000$56.2M2.7%+90,327+18.1%AddedHistory
ANABAnaptysbio, IncCOM826,109$55.8M2.7%−113,891−12.1%ReducedHistory
AVTXAvalo Therapeutics, Inc.COM NEW2,900,000$53.6M2.6%+1,559,160+116.3%AddedHistory
CYTKCytokinetics IncCOM NEW550,000$46.9M2.3%−150,483−21.5%ReducedHistory
RVMDRevolution Medicines, Inc.COM250,000$46.8M2.3%+150,000+150.0%AddedHistory
ABVXAbivax S.A.SPONSORED ADS330,000$44.0M2.2%−75,000−18.5%ReducedHistory
TRAXFirst Tracks Biotherapeutics, Inc.ORD SHS2,032,012$40.9M2.0%+2,032,012NewHistory
DNTHDianthus Therapeutics, Inc.COM400,000$39.0M1.9%+50,000+14.3%AddedHistory
STROSutro Biopharma, Inc.COM SHS1,172,487$38.9M1.9%+102,968+9.6%AddedHistory
NUVLNuvalent, Inc.COM275,000$34.0M1.7%−25,000−8.3%ReducedHistory
TRVITrevi Therapeutics, Inc.COM1,800,172$33.6M1.6%−200,000−10.0%ReducedHistory
OVIDOvid Therapeutics Inc.COM10,144,562$27.3M1.3%−491,756−4.6%ReducedHistory
LXEOLexeo Therapeutics, Inc.COM5,807,611$27.0M1.3%+757,400+15.0%AddedHistory
CLDXCelldex Therapeutics, Inc.COM NEW700,000$26.0M1.3%+200,000+40.0%AddedHistory
BLTEBelite Bio, IncSPONSORED ADS165,000$25.4M1.2%+100,000+153.8%AddedHistory
ELVNEnliven Therapeutics, Inc.COM500,000$25.4M1.2%−86,904−14.8%ReducedHistory
FBRXForte Biosciences, Inc.COM NEW1,145,391$24.3M1.2%+133,501+13.2%AddedHistory
NRIXNurix Therapeutics, Inc.COM967,620$23.5M1.1%00.0%UnchangedHistory
ANROAlto Neuroscience, Inc.COM SHS850,000$22.4M1.1%+350,000+70.0%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM40,000$21.5M1.1%−15,000−27.3%ReducedHistory
PTGXProtagonist Therapeutics, IncCOM172,125$21.1M1.0%00.0%UnchangedHistory
MLYSMineralys Therapeutics, Inc.COM750,000$20.2M1.0%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM1,050,000$19.6M1.0%+650,000+162.5%AddedHistory
SGMTSagimet Biosciences Inc.COM SER A2,497,864$19.3M0.9%+1,629,844+187.8%AddedHistory
JBIOJade Biosciences, Inc.COM NEW840,350$18.7M0.9%+200,394+31.3%AddedHistory
COGTCogent Biosciences, Inc.COM450,000$17.4M0.9%−300,000−40.0%ReducedHistory
TVTXTravere Therapeutics, Inc.COM300,000$17.0M0.8%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM875,760$15.9M0.8%+94,500+12.1%AddedHistory
SVRASavara IncCOM2,512,153$15.5M0.8%00.0%UnchangedHistory
IDYAIDEAYA Biosciences, Inc.COM400,000$14.9M0.7%+400,000NewHistory
CATXPerspective Therapeutics, Inc.COM NEW4,214,582$14.4M0.7%+1,050,000+33.2%AddedHistory
ODTXOdyssey Therapeutics, Inc.COMMON STOCK766,346$14.3M0.7%+766,346NewHistory
Cogent Biosciences, Inc.19240QAA0NOTE 1.625%11/1–$13.7M0.7%–––
HLXCHelix Acquisition Corp. IIIUSD CL A ORD SHS1,250,000$13.3M0.7%00.0%UnchangedHistory
EQEquillium, Inc.COM4,100,000$13.1M0.6%+2,873,690+234.3%AddedHistory
ESTAEstablishment Labs Holdings Inc.COM148,013$12.7M0.6%+48,013+48.0%AddedHistory
CLYMClimb Bio, Inc.COM972,000$12.7M0.6%+272,000+38.9%AddedHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS374,000$12.7M0.6%−1,026,000−73.3%ReducedHistory
MANEVeradermics, IncCOMMON STOCK100,000$12.3M0.6%+30,000+42.9%AddedHistory
ARWRArrowhead Pharmaceuticals, Inc.COM150,000$12.2M0.6%−50,000−25.0%ReducedHistory
Omeros Corp682143AK8NOTE 9.500% 6/1–$12.2M0.6%–––
TSHATaysha Gene Therapies, Inc.COM SHS1,750,000$11.9M0.6%+750,000+75.0%AddedHistory
DMRADamora Therapeutics, Inc.COM NEW425,000$11.1M0.5%−25,000−5.6%ReducedHistory
EPRXEupraxia Pharmaceuticals Inc.COM1,650,000$10.9M0.5%+60,995+3.8%AddedHistory
VERAVera Therapeutics, Inc.CL A250,000$10.7M0.5%00.0%UnchangedHistory
PRQRProQR Therapeutics N.V.SHS EURO5,543,936$10.3M0.5%+3,089,658+125.9%AddedHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES275,000$9.32M0.5%00.0%UnchangedHistory
KRROKorro Bio, Inc.COM706,904$9.32M0.5%00.0%UnchangedHistory
AVRAnteris Technologies Global Corp.COM912,397$8.99M0.4%00.0%UnchangedHistory
ZURAZura Bio LtdCLASS A ORD SHS1,464,303$8.64M0.4%−1,100,000−42.9%ReducedHistory
QUREuniQure N.V.SHS175,000$8.06M0.4%+175,000NewHistory
ASNDAscendis Pharma A/SORD SHS30,000$8.00M0.4%−65,000−68.4%ReducedHistory
IBIOiBio, Inc.COM NEW4,007,881$7.01M0.3%+900,681+29.0%AddedHistory
GENBGenerate Biomedicines, Inc.COM SHS400,000$6.75M0.3%+50,000+14.3%AddedHistory
TYRATyra Biosciences, Inc.COM200,012$6.39M0.3%−57,500−22.3%ReducedHistory
SLGLSol-Gel Technologies Ltd.SHS NEW84,900$6.29M0.3%+49,900+142.6%AddedHistory
SABSSAB Biotherapeutics, Inc.COM NEW1,525,000$5.95M0.3%+950,000+165.2%AddedHistory
MGNXMacrogenics IncCOM1,216,606$5.62M0.3%+716,606+143.3%AddedHistory
CRSPCRISPR Therapeutics AGNAMEN AKT100,000$5.45M0.3%−50,000−33.3%ReducedHistory
NAMSWNewAmsterdam Pharma Co N.V.*W EXP 11/22/202245,000$5.34M0.3%00.0%UnchangedHistory
ASMBAssembly Biosciences, Inc.COM NEW190,000$5.22M0.3%+190,000NewHistory
RZLTRezolute, Inc.COM NEW1,000,000$5.20M0.3%−547,641−35.4%ReducedHistory
DTILPrecision Biosciences IncCOM NEW646,576$5.08M0.2%+48,630+8.1%AddedHistory
COAGHemab Therapeutics Holdings, Inc.COM SHS138,030$5.07M0.2%+138,030NewHistory
VRDNViridian Therapeutics, Inc.COM250,000$4.59M0.2%00.0%UnchangedHistory
AVBPArriVent BioPharma, Inc.COM125,000$4.34M0.2%−50,000−28.6%ReducedHistory
VRCAVerrica Pharmaceuticals Inc.COM SHS707,338$4.33M0.2%00.0%UnchangedHistory
CMPSCOMPASS Pathways plcSPONSORED ADS301,183$4.26M0.2%−807,300−72.8%ReducedHistory
MBXMBX Biosciences, Inc.COM75,000$4.14M0.2%−75,000−50.0%ReducedHistory
RACCResearch Alliance Corp IIIORD SHS CL A370,000$3.96M0.2%+370,000NewHistory
IMVTImmunovant, Inc.COM100,000$3.85M0.2%00.0%UnchangedHistory
AMANAmanat Acquisition Corp.CL A ORD375,000$3.81M0.2%+375,000NewHistory
BHVNBiohaven Ltd.COM250,000$3.72M0.2%+250,000NewHistory
FTHFaeth Therapeutics, Inc.COM NEW144,404$3.61M0.2%+144,404NewHistory
KPTIKaryopharm Therapeutics Inc.COM NEW312,500$3.05M0.1%−187,500−37.5%ReducedHistory
ALECAlector, Inc.COM1,510,000$3.04M0.1%+1,010,000+202.0%AddedHistory
SGPSpyGlass Pharma, Inc.COM SHS131,586$2.93M0.1%−118,414−47.4%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM75,000$2.81M0.1%00.0%UnchangedHistory
OACCUOaktree Acquisition Corp. III Life SciencesUNIT 10/04/2029250,000$2.75M0.1%00.0%UnchangedHistory
Celcuity Inc.15102KAB6NOTE 0.250% 8/0–$2.28M0.1%–New–
JATTJATT II Acquisition Corp.ORD SHS200,000$2.27M0.1%+200,000NewHistory
NMRANeumora Therapeutics, Inc.COM1,070,651$1.82M0.1%+1,070,651NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM98,999$1.78M0.1%+98,999NewHistory
ANLAdlai Nortye Group Ltd.ADS153,847$1.77M0.1%−10,901−6.6%ReducedHistory
SPRBSpruce Biosciences, Inc.COM NEW30,000$1.62M0.1%+30,000NewHistory
EIKNEikon Therapeutics, Inc.COM98,001$1.28M0.1%+98,001NewHistory
OKUROnKure Therapeutics, Inc.COM CL A240,963$1.10M0.1%00.0%UnchangedHistory
ENGNenGene Therapeutics Inc.COM600,000$1.04M0.1%−10,370−1.7%ReducedHistory
XFORX4 Pharmaceuticals, IncCOM NEW145,000$677.1K<0.1%00.0%UnchangedHistory
BOLDBoundless Bio, Inc.COM250,000$625.0K<0.1%+250,000NewHistory
LENZLENZ Therapeutics, Inc.COM100,000$568.0K<0.1%00.0%UnchangedHistory
QTTBQ32 Bio Inc.COM27,777$353.9K<0.1%00.0%UnchangedHistory

Options (8)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Affinity Asset Advisors, LLC in Q2 2026
SecurityClassPutsCalls
MRNAModerna, Inc.Stock$35.0M$33.3M
ARK ETF Tr00214Q302GENOMIC REV ETF–$31.5M
LLYEli Lilly & CoStock–$24.0M
OMEROmeros CorpCOM$13.4M–
ALKSAlkermes plc.SHS–$13.1M
QUREuniQure N.V.SHS–$9.21M
EVMNEvommune, Inc.COM SHS$6.65M–
SMMTSummit Therapeutics Inc.COM–$1.46M

Sold out since Q1 2026 (8)

Positions held at the end of Q1 2026 that are gone from this filing.

Positions of Affinity Asset Advisors, LLC sold out since Q1 2026
SecurityClassShares in Q1 2026Value in Q1 2026% of portfolio in Q1 2026History
CNTACentessa Pharmaceuticals plcSPONSORED ADS1,400,000$55.6M3.3%History
ACLXArcellx, Inc.COMMON STOCK362,764$41.7M2.4%History
TERNTerns Pharmaceuticals, Inc.COM562,631$29.7M1.7%History
BBIOBridgeBio Pharma, Inc.COM150,000$11.1M0.7%History
WVEWave Life Sciences, Inc.SHS1,401,727$10.2M0.6%History
Celcuity Inc.15102KAA8NOTE 2.750% 8/0–$7.31M0.4%–
CORTCorcept Therapeutics IncCOM50,000$2.02M0.1%History
KZRKezar Life Sciences, Inc.COM229,076$1.70M0.1%History