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Affinity Asset Advisors, LLC

SEC CIK
0001773195
Latest filing
Aug 13, 2026

Holdings in Q1 2026

Holdings as of Mar 31, 2026, filed May 14, 2026. Long positions only; changes compare share counts with Q4 2025.

Institution overview
Positions
95
+9 vs. Q4 2025
Portfolio value
$1.71B
+$313.3M (+22.5%) vs. Q4 2025
Filed
May 14, 2026
SEC
Holdings of Affinity Asset Advisors, LLC in Q1 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
Rocket Pharmaceuticals, Inc.77313F114*W EXP 09/02/20275,000$1.18K<0.1%00.0%Unchanged–
ADGMAdagio Medical Holdings, Inc.COM80,000$92.0K<0.1%00.0%UnchangedHistory
QTTBQ32 Bio Inc.COM27,777$178.3K<0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM NEW145,000$598.9K<0.1%00.0%UnchangedHistory
LENZLENZ Therapeutics, Inc.COM100,000$915.0K0.1%+100,000NewHistory
OKUROnKure Therapeutics, Inc.COM CL A240,963$997.6K0.1%+240,963NewHistory
ALECAlector, Inc.COM500,000$1.07M0.1%+500,000NewHistory
ANLAdlai Nortye Group Ltd.ADS164,748$1.14M0.1%+164,748NewHistory
MGNXMacrogenics IncCOM500,000$1.45M0.1%+15,692+3.2%AddedHistory
KZRKezar Life Sciences, Inc.COM229,076$1.70M0.1%00.0%UnchangedHistory
OBIOOrchestra BioMed Holdings, Inc.COM402,550$1.71M0.1%−170,254−29.7%ReducedHistory
CORTCorcept Therapeutics IncCOM50,000$2.02M0.1%+50,000NewHistory
SABSSAB Biotherapeutics, Inc.COM NEW575,000$2.20M0.1%+575,000NewHistory
EQEquillium, Inc.COM1,226,310$2.45M0.1%+1,226,310NewHistory
IMVTImmunovant, Inc.COM100,000$2.48M0.1%−100,000−50.0%ReducedHistory
NXTCNextCure, Inc.COM NEW241,826$2.58M0.2%−5,468−2.2%ReducedHistory
OACCUOaktree Acquisition Corp. III Life SciencesUNIT 10/04/2029250,000$2.66M0.2%00.0%UnchangedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM75,000$2.72M0.2%00.0%UnchangedHistory
SLGLSol-Gel Technologies Ltd.SHS NEW35,000$2.77M0.2%+35,000NewHistory
KPTIKaryopharm Therapeutics Inc.COM NEW500,000$2.79M0.2%−389,575−43.8%ReducedHistory
DTILPrecision Biosciences IncCOM NEW597,946$3.29M0.2%+597,946NewHistory
VRCAVerrica Pharmaceuticals Inc.COM SHS707,338$3.74M0.2%00.0%UnchangedHistory
PRQRProQR Therapeutics N.V.SHS EURO2,454,278$3.98M0.2%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM400,000$3.98M0.2%+400,000NewHistory
AVBPArriVent BioPharma, Inc.COM175,000$4.04M0.2%+25,000+16.7%AddedHistory
ENGNenGene Therapeutics Inc.COM610,370$4.16M0.2%−33,000−5.1%ReducedHistory
GENBGenerate Biomedicines, Inc.COM SHS350,000$4.38M0.3%+350,000NewHistory
MANEVeradermics, IncCOMMON STOCK70,000$4.42M0.3%+70,000NewHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,000,000$4.47M0.3%−2,300,000−69.7%ReducedHistory
MBXMBX Biosciences, Inc.COM150,000$4.48M0.3%−100,000−40.0%ReducedHistory
SGMTSagimet Biosciences Inc.COM SER A868,020$4.54M0.3%−280,225−24.4%ReducedHistory
RZLTRezolute, Inc.COM NEW1,547,641$4.72M0.3%−803,503−34.2%ReducedHistory
CLYMClimb Bio, Inc.COM700,000$4.79M0.3%−600,000−46.2%ReducedHistory
VRDNViridian Therapeutics, Inc.COM250,000$4.89M0.3%00.0%UnchangedHistory
NAMSWNewAmsterdam Pharma Co N.V.*W EXP 11/22/202245,000$4.91M0.3%00.0%UnchangedHistory
AVRAnteris Technologies Global Corp.COM912,397$5.06M0.3%+425,713+87.5%AddedHistory
ESTAEstablishment Labs Holdings Inc.COM100,000$5.68M0.3%−100,000−50.0%ReducedHistory
IBIOiBio, Inc.COM NEW3,107,200$5.90M0.3%+1,050,000+51.0%AddedHistory
CMPSCOMPASS Pathways plcSPONSORED ADS1,108,483$6.13M0.4%+908,483+454.2%AddedHistory
SGPSpyGlass Pharma, Inc.COM SHS250,000$6.48M0.4%+250,000NewHistory
CRSPCRISPR Therapeutics AGNAMEN AKT150,000$7.14M0.4%+150,000NewHistory
Celcuity Inc.15102KAA8NOTE 2.750% 8/0–$7.31M0.4%–––
KRROKorro Bio, Inc.COM706,904$8.00M0.5%+706,904NewHistory
Cogent Biosciences, Inc.19240QAA0NOTE 1.625%11/1–$8.59M0.5%–––
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES275,000$8.80M0.5%00.0%UnchangedHistory
TVTXTravere Therapeutics, Inc.COM300,000$8.91M0.5%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM NEW639,956$8.99M0.5%−75,000−10.5%ReducedHistory
RVMDRevolution Medicines, Inc.COM100,000$9.72M0.6%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM257,512$9.86M0.6%+257,512NewHistory
VERAVera Therapeutics, Inc.CL A250,000$10.1M0.6%00.0%UnchangedHistory
WVEWave Life Sciences, Inc.SHS1,401,727$10.2M0.6%−1,298,273−48.1%ReducedHistory
BLTEBelite Bio, IncSPONSORED ADS65,000$10.4M0.6%+45,000+225.0%AddedHistory
CGEMCullinan Therapeutics, Inc.COM781,260$11.1M0.7%−1,150,846−59.6%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM150,000$11.1M0.7%−170,000−53.1%ReducedHistory
ANROAlto Neuroscience, Inc.COM SHS500,000$11.2M0.7%+500,000NewHistory
EPRXEupraxia Pharmaceuticals Inc.COM1,589,005$11.5M0.7%+1,289,005+429.7%AddedHistory
DMRADamora Therapeutics, Inc.COM NEW450,000$11.7M0.7%+450,000NewHistory
ARWRArrowhead Pharmaceuticals, Inc.COM200,000$12.5M0.7%+130,000+185.7%AddedHistory
HLXCHelix Acquisition Corp. IIIUSD CL A ORD SHS1,250,000$12.7M0.7%+1,250,000NewHistory
CATXPerspective Therapeutics, Inc.COM NEW3,164,582$13.2M0.8%+2,864,582+954.9%AddedHistory
Omeros Corp682143AK8NOTE 9.500% 6/1–$13.2M0.8%–––
SVRASavara IncCOM2,512,153$13.7M0.8%−285,000−10.2%ReducedHistory
NRIXNurix Therapeutics, Inc.COM967,620$15.0M0.9%00.0%UnchangedHistory
ZURAZura Bio LtdCLASS A ORD SHS2,564,303$15.3M0.9%+750,632+41.4%AddedHistory
CLDXCelldex Therapeutics, Inc.COM NEW500,000$15.9M0.9%+150,000+42.9%AddedHistory
PTGXProtagonist Therapeutics, IncCOM172,125$18.1M1.1%00.0%UnchangedHistory
AVTXAvalo Therapeutics, Inc.COM NEW1,340,840$20.0M1.2%+289,786+27.6%AddedHistory
MLYSMineralys Therapeutics, Inc.COM750,000$20.3M1.2%+20,000+2.7%AddedHistory
ASNDAscendis Pharma A/SSPONSORED ADR95,000$21.7M1.3%+65,000+216.7%AddedHistory
ELVNEnliven Therapeutics, Inc.COM586,904$23.0M1.3%+586,904NewHistory
OVIDOvid Therapeutics Inc.COM10,636,318$23.6M1.4%+3,486,318+48.8%AddedHistory
TRVITrevi Therapeutics, Inc.COM2,000,172$23.9M1.4%−150,000−7.0%ReducedHistory
ORKAOruka Therapeutics, Inc.COM499,673$24.5M1.4%−302,669−37.7%ReducedHistory
FBRXForte Biosciences, Inc.COM NEW1,011,890$26.2M1.5%+22,400+2.3%AddedHistory
STROSutro Biopharma, Inc.COM SHS1,069,519$26.6M1.6%+321,137+42.9%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM55,000$28.8M1.7%+23,869+76.7%AddedHistory
COGTCogent Biosciences, Inc.COM750,000$28.9M1.7%+400,000+114.3%AddedHistory
LXEOLexeo Therapeutics, Inc.COM5,050,211$29.0M1.7%+1,850,211+57.8%AddedHistory
DNTHDianthus Therapeutics, Inc.COM350,000$29.4M1.7%+235,000+204.3%AddedHistory
TERNTerns Pharmaceuticals, Inc.COM562,631$29.7M1.7%+12,631+2.3%AddedHistory
NUVLNuvalent, Inc.COM300,000$30.7M1.8%−22,633−7.0%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK362,764$41.7M2.4%−160,961−30.7%ReducedHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS1,400,000$42.2M2.5%00.0%UnchangedHistory
ABVXAbivax S.A.SPONSORED ADS405,000$45.1M2.6%−100,000−19.8%ReducedHistory
CYTKCytokinetics IncCOM NEW700,483$46.2M2.7%−99,517−12.4%ReducedHistory
ALKSAlkermes plc.SHS1,350,000$47.7M2.8%+350,000+35.0%AddedHistory
ANABAnaptysbio, IncCOM940,000$52.1M3.1%+495,308+111.4%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW170,000$54.8M3.2%−15,000−8.1%ReducedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS1,400,000$55.6M3.3%+799,448+133.1%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW1,279,134$64.5M3.8%−153,457−10.7%ReducedHistory
ROIVRoivant Sciences Ltd.SHS2,800,000$77.6M4.5%+1,100,000+64.7%AddedHistory
INSMINSMED IncCOM PAR $.01480,000$78.5M4.6%+30,000+6.7%AddedHistory
ERASErasca, Inc.COM5,350,000$86.6M5.1%+1,450,000+37.2%AddedHistory
XENEXenon Pharmaceuticals Inc.COM1,675,000$97.4M5.7%+425,000+34.0%AddedHistory
APGEApogee Therapeutics, Inc.COM1,284,926$108.2M6.3%+50,000+4.0%AddedHistory

Options (10)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Affinity Asset Advisors, LLC in Q1 2026
SecurityClassPutsCalls
SPYSPDR S&P 500 ETF TrustETF$130.1M–
MRNAModerna, Inc.Stock–$40.6M
BMYBristol Myers Squibb CoStock–$18.2M
RVMDRevolution Medicines, Inc.COM$9.72M–
IBRXImmunityBio, Inc.COM$9.59M–
NVONovo Nordisk A SADR–$6.43M
QUREuniQure N.V.SHS–$4.91M
DNTHDianthus Therapeutics, Inc.COM–$4.20M
CGONCG Oncology, Inc.COM–$4.06M
CELCCelcuity Inc.COM–$3.42M

Sold out since Q4 2025 (11)

Positions held at the end of Q4 2025 that are gone from this filing.

Positions of Affinity Asset Advisors, LLC sold out since Q4 2025
SecurityClassShares in Q4 2025Value in Q4 2025% of portfolio in Q4 2025History
VTYXVentyx Biosciences, Inc.COM6,484,558$58.6M4.2%History
Travere Therapeutics, Inc.89422GAA5NOTE 2.250% 3/0–$9.99M0.7%–
TNGXTango Therapeutics, Inc.COM1,000,000$8.86M0.6%History
RCUSArcus Biosciences, Inc.COM300,000$7.15M0.5%History
AVDLAvadel Pharmaceuticals PLCStock250,000$5.39M0.4%History
AMGNAmgen IncStock10,000$3.27M0.2%History
MRSNMersana Therapeutics, Inc.COMMON STOCK100,000$2.89M0.2%History
GERNGeron CorpCOM1,500,000$1.98M0.1%History
RAREUltragenyx Pharmaceutical Inc.COM75,000$1.73M0.1%History
QUREuniQure N.V.SHS50,000$1.20M0.1%History
FRNMFreenome, Inc.CL A ORD SHS50,000$651.5K<0.1%History