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Ghost Tree Capital, LLC

SEC CIK
0001595851
Latest filing
Nov 14, 2024

Holdings in Q3 2024

Holdings as of Sep 30, 2024, filed Nov 14, 2024. Long positions only; changes compare share counts with Q2 2024.

Institution overview
Positions
51
−8 vs. Q2 2024
Portfolio value
$293.2M
+$5.86M (+2.0%) vs. Q2 2024
Filed
Nov 14, 2024
SEC
Holdings of Ghost Tree Capital, LLC in Q3 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
Biohaven LtdG1110E907CALL348,778$17.4M5.9%+348,778New–
SRPTSarepta Therapeutics, Inc.COM120,000$15.0M5.1%+65,000+118.2%AddedHistory
NVONovo Nordisk A SADR110,000$13.1M4.5%+110,000NewHistory
BPMCBlueprint Medicines CorpCOM140,000$12.9M4.4%+100,000+250.0%AddedHistory
AXSMAxsome Therapeutics, Inc.COM135,000$12.1M4.1%−15,000−10.0%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM350,000$11.5M3.9%+115,000+48.9%AddedHistory
CATXPerspective Therapeutics, Inc.COM NEW750,000$10.0M3.4%−175,000−18.9%ReducedHistory
CGONCG Oncology, Inc.COM250,000$9.43M3.2%−10,000−3.8%ReducedHistory
ROIVRoivant Sciences Ltd.SHS800,000$9.23M3.1%−200,000−20.0%ReducedHistory
PCVXVaxcyte, Inc.COM80,000$9.14M3.1%−70,000−46.7%ReducedHistory
VKTXViking Therapeutics, Inc.COM140,000$8.86M3.0%+45,000+47.4%AddedHistory
SNDXSyndax Pharmaceuticals IncCOM450,000$8.66M3.0%+100,000+28.6%AddedHistory
JANXJanux Therapeutics, Inc.COM190,000$8.63M2.9%+140,000+280.0%AddedHistory
ASNDAscendis Pharma A/SSPONSORED ADR52,500$7.84M2.7%−34,221−39.5%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM150,000$7.67M2.6%−90,000−37.5%ReducedHistory
SLNOSoleno Therapeutics IncCOM150,000$7.57M2.6%−150,000−50.0%ReducedHistory
TGTXTG Therapeutics, Inc.COM310,000$7.25M2.5%−190,000−38.0%ReducedHistory
RZLTRezolute, Inc.COM NEW1,474,995$7.15M2.4%+53,494+3.8%AddedHistory
PHATPhathom Pharmaceuticals, Inc.COM375,000$6.78M2.3%−225,000−37.5%ReducedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD128,411$6.47M2.2%−171,589−57.2%ReducedHistory
OLMAOlema Pharmaceuticals, Inc.COM535,000$6.39M2.2%−15,000−2.7%ReducedHistory
IMVTImmunovant, Inc.COM215,000$6.13M2.1%−45,000−17.3%ReducedHistory
INSMINSMED IncCOM PAR $.0175,000$5.47M1.9%+10,000+15.4%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM195,000$5.20M1.8%+195,000NewHistory
REPLReplimune Group, Inc.COM450,000$4.93M1.7%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM175,000$4.46M1.5%+35,000+25.0%AddedHistory
TSHATaysha Gene Therapies, Inc.COM SHS2,150,000$4.32M1.5%+900,000+72.0%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM78,842$4.13M1.4%−38,546−32.8%ReducedHistory
ANNXAnnexon, Inc.COM650,000$3.85M1.3%+340,000+109.7%AddedHistory
KRROKorro Bio, Inc.COM110,000$3.68M1.3%+10,000+10.0%AddedHistory
DYNDyne Therapeutics, Inc.COM100,000$3.59M1.2%+100,000NewHistory
ARVNArvinas, Inc.COM145,000$3.57M1.2%+70,000+93.3%AddedHistory
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW160,000$3.30M1.1%−15,000−8.6%ReducedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS300,000$3.13M1.1%00.0%UnchangedHistory
NUVBNuvation Bio Inc.COM CL A1,350,000$3.09M1.1%+200,000+17.4%AddedHistory
SVRASavara IncCOM725,000$3.07M1.0%−325,876−31.0%ReducedHistory
TNYATenaya Therapeutics, Inc.COM1,500,000$2.90M1.0%+150,000+11.1%AddedHistory
RGNXREGENXBIO Inc.COM265,000$2.78M0.9%+95,000+55.9%AddedHistory
CRVSCorvus Pharmaceuticals, Inc.COM500,000$2.64M0.9%+500,000NewHistory
ABSIAbsci CorpCOM550,000$2.10M0.7%+550,000NewHistory
NGNENeurogene Inc.COM50,000$2.10M0.7%−20,000−28.6%ReducedHistory
CAPRCapricor Therapeutics, Inc.COM NEW125,000$1.90M0.6%+125,000NewHistory
APLSApellis Pharmaceuticals, Inc.COM65,000$1.87M0.6%−70,000−51.9%ReducedHistory
SMMTSummit Therapeutics Inc.COM85,000$1.86M0.6%+85,000NewHistory
SYRESpyre Therapeutics, Inc.COM NEW60,000$1.76M0.6%−190,237−76.0%ReducedHistory
VRDNViridian Therapeutics, Inc.COM75,000$1.71M0.6%−512,708−87.2%ReducedHistory
PRQRProQR Therapeutics N.V.SHS EURO887,700$1.62M0.6%−12,300−1.4%ReducedHistory
ATYRaTYR PHARMA INCCOM NEW800,000$1.41M0.5%00.0%UnchangedHistory
LRMRLarimar Therapeutics, Inc.COM200,000$1.31M0.4%+200,000NewHistory
ENGNenGene Therapeutics Inc.COM160,898$1.06M0.4%−259,433−61.7%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM325,000$1.05M0.4%+325,000NewHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ghost Tree Capital, LLC in Q3 2024
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$29.6M–
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW$4.54M–
INSMINSMED IncCOM PAR $.01–$3.65M

Sold out since Q2 2024 (18)

Positions held at the end of Q2 2024 that are gone from this filing.

Positions of Ghost Tree Capital, LLC sold out since Q2 2024
SecurityClassShares in Q2 2024Value in Q2 2024% of portfolio in Q2 2024History
BHVNBiohaven Ltd.COM490,000$17.0M5.9%History
ALNYAlnylam Pharmaceuticals, Inc.COM22,500$5.47M1.9%History
ACADAcadia Pharmaceuticals IncCOM225,000$3.66M1.3%History
CABACabaletta Bio, Inc.COM370,899$2.77M1.0%History
CYTKCytokinetics IncCOM NEW33,200$1.80M0.6%History
ELEVElevation Acquisition Group Inc.COM600,000$1.62M0.6%History
KRYSKrystal Biotech, Inc.COM8,500$1.56M0.5%History
WVEWave Life Sciences, Inc.SHS200,000$998.0K0.3%History
ARWRArrowhead Pharmaceuticals, Inc.COM35,000$909.6K0.3%History
SGMTSagimet Biosciences Inc.COM SER A225,000$769.5K0.3%History
ITCIIntra-Cellular Therapies, Inc.COM10,000$684.9K0.2%History
MGNXMacrogenics IncCOM150,000$637.5K0.2%History
PMVPPMV Pharmaceuticals, Inc.COM375,000$607.5K0.2%History
PTCTPTC Therapeutics, Inc.COM19,000$581.0K0.2%History
RVNCRevance Therapeutics, Inc.COM225,000$578.3K0.2%History
NTLAIntellia Therapeutics, Inc.COM25,000$559.5K0.2%History
ANTXAN2 Therapeutics, Inc.COM219,331$471.6K0.2%History
CTMXCytomX Therapeutics, Inc.COM300,000$366.0K0.1%History