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Ghost Tree Capital, LLC

SEC CIK
0001595851
Latest filing
Nov 14, 2024

Holdings in Q2 2024

Holdings as of Jun 30, 2024, filed Aug 14, 2024. Long positions only; changes compare share counts with Q1 2024.

Institution overview
Positions
59
−6 vs. Q1 2024
Portfolio value
$287.4M
−$23.7M (−7.6%) vs. Q1 2024
Filed
Aug 14, 2024
SEC
Holdings of Ghost Tree Capital, LLC in Q2 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
BHVNBiohaven Ltd.COM490,000$17.0M5.9%+205,000+71.9%AddedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD300,000$13.2M4.6%00.0%UnchangedHistory
SLNOSoleno Therapeutics IncCOM300,000$12.2M4.3%+100,000+50.0%AddedHistory
AXSMAxsome Therapeutics, Inc.COM150,000$12.1M4.2%−60,000−28.6%ReducedHistory
ASNDAscendis Pharma A/SSPONSORED ADR86,721$11.8M4.1%+86,721NewHistory
PCVXVaxcyte, Inc.COM150,000$11.3M3.9%+55,000+57.9%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM240,000$10.7M3.7%+40,000+20.0%AddedHistory
ROIVRoivant Sciences Ltd.SHS1,000,000$10.6M3.7%−300,000−23.1%ReducedHistory
CATXPerspective Therapeutics, Inc.COM NEW925,000$9.22M3.2%+925,000NewHistory
TGTXTG Therapeutics, Inc.COM500,000$8.89M3.1%−325,000−39.4%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM55,000$8.69M3.0%−70,000−56.0%ReducedHistory
CGONCG Oncology, Inc.COM260,000$8.21M2.9%+185,000+246.7%AddedHistory
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW175,000$7.92M2.8%+118,059+207.3%AddedHistory
VRDNViridian Therapeutics, Inc.COM587,708$7.65M2.7%−37,292−6.0%ReducedHistory
SNDXSyndax Pharmaceuticals IncCOM350,000$7.19M2.5%+200,000+133.3%AddedHistory
IMVTImmunovant, Inc.COM260,000$6.86M2.4%+135,000+108.0%AddedHistory
TARSTarsus Pharmaceuticals, Inc.COM235,000$6.39M2.2%−65,000−21.7%ReducedHistory
PHATPhathom Pharmaceuticals, Inc.COM600,000$6.18M2.2%+115,000+23.7%AddedHistory
RZLTRezolute, Inc.COM NEW1,421,501$6.11M2.1%+1,421,501NewHistory
OLMAOlema Pharmaceuticals, Inc.COM550,000$5.95M2.1%+350,000+175.0%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW250,237$5.88M2.0%+150,237+150.2%AddedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM22,500$5.47M1.9%−37,500−62.5%ReducedHistory
APLSApellis Pharmaceuticals, Inc.COM135,000$5.18M1.8%+5,000+3.8%AddedHistory
VKTXViking Therapeutics, Inc.COM95,000$5.04M1.8%+21,998+30.1%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM117,388$4.82M1.7%−7,612−6.1%ReducedHistory
INSMINSMED IncCOM PAR $.0165,000$4.36M1.5%−85,000−56.7%ReducedHistory
BPMCBlueprint Medicines CorpCOM40,000$4.31M1.5%−32,761−45.0%ReducedHistory
SVRASavara IncCOM1,050,876$4.24M1.5%−549,124−34.3%ReducedHistory
TNYATenaya Therapeutics, Inc.COM1,350,000$4.18M1.5%+575,000+74.2%AddedHistory
REPLReplimune Group, Inc.COM450,000$4.05M1.4%−200,000−30.8%ReducedHistory
ENGNenGene Therapeutics Inc.COM420,331$3.96M1.4%+220,331+110.2%AddedHistory
ACADAcadia Pharmaceuticals IncCOM225,000$3.66M1.3%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM140,000$3.55M1.2%−35,000−20.0%ReducedHistory
KRROKorro Bio, Inc.COM100,000$3.39M1.2%+100,000NewHistory
NUVBNuvation Bio Inc.COM CL A1,150,000$3.36M1.2%+1,150,000NewHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS300,000$3.07M1.1%00.0%UnchangedHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,250,000$2.80M1.0%+300,000+31.6%AddedHistory
CABACabaletta Bio, Inc.COM370,899$2.77M1.0%−4,101−1.1%ReducedHistory
NGNENeurogene Inc.COM70,000$2.55M0.9%+45,000+180.0%AddedHistory
JANXJanux Therapeutics, Inc.COM50,000$2.09M0.7%+50,000NewHistory
ARVNArvinas, Inc.COM75,000$2.00M0.7%+35,000+87.5%AddedHistory
RGNXREGENXBIO Inc.COM170,000$1.99M0.7%+50,000+41.7%AddedHistory
CYTKCytokinetics IncCOM NEW33,200$1.80M0.6%+13,200+66.0%AddedHistory
ELEVElevation Acquisition Group Inc.COM600,000$1.62M0.6%+350,000+140.0%AddedHistory
KRYSKrystal Biotech, Inc.COM8,500$1.56M0.5%−5,500−39.3%ReducedHistory
ANNXAnnexon, Inc.COM310,000$1.52M0.5%+310,000NewHistory
PRQRProQR Therapeutics N.V.SHS EURO900,000$1.49M0.5%+900,000NewHistory
ATYRaTYR PHARMA INCCOM NEW800,000$1.25M0.4%+200,000+33.3%AddedHistory
WVEWave Life Sciences, Inc.SHS200,000$998.0K0.3%+200,000NewHistory
ARWRArrowhead Pharmaceuticals, Inc.COM35,000$909.6K0.3%00.0%UnchangedHistory
SGMTSagimet Biosciences Inc.COM SER A225,000$769.5K0.3%00.0%UnchangedHistory
ITCIIntra-Cellular Therapies, Inc.COM10,000$684.9K0.2%+10,000NewHistory
MGNXMacrogenics IncCOM150,000$637.5K0.2%+150,000NewHistory
PMVPPMV Pharmaceuticals, Inc.COM375,000$607.5K0.2%−300,000−44.4%ReducedHistory
PTCTPTC Therapeutics, Inc.COM19,000$581.0K0.2%+19,000NewHistory
RVNCRevance Therapeutics, Inc.COM225,000$578.3K0.2%−225,000−50.0%ReducedHistory
NTLAIntellia Therapeutics, Inc.COM25,000$559.5K0.2%00.0%UnchangedHistory
ANTXAN2 Therapeutics, Inc.COM219,331$471.6K0.2%00.0%UnchangedHistory
CTMXCytomX Therapeutics, Inc.COM300,000$366.0K0.1%−300,000−50.0%ReducedHistory

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ghost Tree Capital, LLC in Q2 2024
SecurityClassPutsCalls
ALNYAlnylam Pharmaceuticals, Inc.COM$16.6M–
INSMINSMED IncCOM PAR $.01–$13.4M
ANNXAnnexon, Inc.COM–$1.05M
RAPTRAPT Therapeutics, Inc.COM–$915.0K

Sold out since Q1 2024 (18)

Positions held at the end of Q1 2024 that are gone from this filing.

Positions of Ghost Tree Capital, LLC sold out since Q1 2024
SecurityClassShares in Q1 2024Value in Q1 2024% of portfolio in Q1 2024History
CATXPerspective Therapeutics, Inc.COM6,000,000$7.14M2.3%History
JBIOJade Biosciences, Inc.COM225,000$6.65M2.1%History
GPCRStructure Therapeutics Inc.SPONSORED ADS75,000$3.21M1.0%History
COGTCogent Biosciences, Inc.COM450,000$3.02M1.0%History
AQSTAquestive Therapeutics, Inc.COM702,941$2.99M1.0%History
DCPHDeciphera Pharmaceuticals, Inc.COM176,513$2.78M0.9%History
GERNGeron CorpCOM800,000$2.64M0.8%History
MRNSMarinus Pharmaceuticals, Inc.COM NEW285,000$2.58M0.8%History
ALTAltimmune, Inc.COM NEW250,000$2.54M0.8%History
KALVKalVista Pharmaceuticals, Inc.COM200,000$2.37M0.8%History
NTRANatera, Inc.COM25,000$2.29M0.7%History
PTGXProtagonist Therapeutics, IncCOM75,000$2.17M0.7%History
EYPTEyePoint, Inc.COM NEW90,000$1.86M0.6%History
MDGLMadrigal Pharmaceuticals, Inc.COM6,500$1.74M0.6%History
ATXSAstria Therapeutics, Inc.COM115,000$1.62M0.5%History
LRMRLarimar Therapeutics, Inc.COM210,603$1.60M0.5%History
RAREUltragenyx Pharmaceutical Inc.COM20,000$933.8K0.3%History
QUREuniQure N.V.SHS165,000$858.0K0.3%History