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Livermore
Livermore
ZHEN

Ghost Tree Capital, LLC

SEC CIK
0001595851
Latest filing
Nov 14, 2024

Holdings in Q3 2023

Holdings as of Sep 30, 2023, filed Nov 14, 2023. Long positions only; changes compare share counts with Q2 2023.

Institution overview
Positions
58
+3 vs. Q2 2023
Portfolio value
$206.5M
−$70.6M (−25.5%) vs. Q2 2023
Filed
Nov 14, 2023
SEC
Holdings of Ghost Tree Capital, LLC in Q3 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
MRSNMersana Therapeutics, Inc.COM61,250$77.8K<0.1%00.0%UnchangedHistory
Rain Oncology Inc.75082Q105COM325,000$280.1K0.1%00.0%Unchanged–
Avidity Biosciences, Inc.05370A108COM65,000$414.7K0.2%00.0%Unchanged–
ETNB89bio, Inc.COM30,000$463.2K0.2%+30,000NewHistory
ABOSAcumen Pharmaceuticals, Inc.COM150,000$622.5K0.3%+150,000NewHistory
FUSNFusion Pharmaceuticals Inc.COM243,287$632.5K0.3%−169,412−41.0%ReducedHistory
INBXInhibrx Biosciences, Inc.COM35,000$642.3K0.3%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS45,000$733.5K0.4%−65,000−59.1%ReducedHistory
ROIVRoivant Sciences Ltd.SHS64,000$747.5K0.4%00.0%UnchangedHistory
BMEABiomea Fusion, Inc.COM65,000$894.4K0.4%−125,000−65.8%ReducedHistory
KALVKalVista Pharmaceuticals, Inc.COM100,000$963.0K0.5%+100,000NewHistory
WHWKWhitehawk Therapeutics, Inc.COM250,000$1.21M0.6%00.0%UnchangedHistory
VTYXVentyx Biosciences, Inc.COM35,000$1.22M0.6%+35,000NewHistory
ARGXArgenx SESPONSORED ADR2,500$1.23M0.6%+2,500NewHistory
TVTXTravere Therapeutics, Inc.COM150,000$1.34M0.6%+150,000NewHistory
RCUSArcus Biosciences, Inc.COM75,000$1.35M0.7%00.0%UnchangedHistory
QUREuniQure N.V.SHS215,000$1.44M0.7%00.0%UnchangedHistory
LEGNLegend Biotech CorpSPONSORED ADS22,500$1.51M0.7%+22,500NewHistory
ACADAcadia Pharmaceuticals IncCOM80,000$1.67M0.8%+80,000NewHistory
BBIOBridgeBio Pharma, Inc.COM75,000$1.98M1.0%+33,000+78.6%AddedHistory
ZNTLZentalis Pharmaceuticals, Inc.COM100,000$2.01M1.0%00.0%UnchangedHistory
SLRNACELYRIN, Inc.COM200,000$2.03M1.0%+200,000NewHistory
KRTXKaruna Therapeutics, Inc.COM12,500$2.11M1.0%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM175,000$2.13M1.0%−25,000−12.5%ReducedHistory
ATXSAstria Therapeutics, Inc.COM300,000$2.24M1.1%−173−0.1%ReducedHistory
VKTXViking Therapeutics, Inc.COM225,000$2.49M1.2%−425,000−65.4%ReducedHistory
EYPTEyePoint, Inc.COM NEW325,000$2.60M1.3%+325,000NewHistory
MRTXMirati Therapeutics, Inc.COM60,000$2.61M1.3%−140,000−70.0%ReducedHistory
CYTKCytokinetics IncCOM NEW90,000$2.65M1.3%+90,000NewHistory
Morphosys AG617760202SPONSORED ADS400,000$2.69M1.3%+400,000New–
JBIOJade Biosciences, Inc.COM201,197$2.73M1.3%00.0%UnchangedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS55,000$2.77M1.3%+55,000NewHistory
IMGNImmunoGen, Inc.COM175,000$2.78M1.3%+75,000+75.0%AddedHistory
SNDXSyndax Pharmaceuticals IncCOM200,000$2.90M1.4%−150,000−42.9%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM101,443$3.02M1.5%+101,443NewHistory
XENEXenon Pharmaceuticals Inc.COM98,951$3.38M1.6%−86,049−46.5%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM215,000$3.94M1.9%−335,000−60.9%ReducedHistory
RVNCRevance Therapeutics, Inc.COM350,000$4.01M1.9%−175,000−33.3%ReducedHistory
PHATPhathom Pharmaceuticals, Inc.COM395,000$4.10M2.0%+240,750+156.1%AddedHistory
DCPHDeciphera Pharmaceuticals, Inc.COM325,000$4.13M2.0%+325,000NewHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,325,000$4.19M2.0%+1,325,000NewHistory
VRDNViridian Therapeutics, Inc.COM275,000$4.22M2.0%+35,000+14.6%AddedHistory
PMVPPMV Pharmaceuticals, Inc.COM705,881$4.33M2.1%+424,900+151.2%AddedHistory
SRPTSarepta Therapeutics, Inc.COM40,000$4.85M2.3%−45,000−52.9%ReducedHistory
IMVTImmunovant, Inc.COM130,000$4.99M2.4%+130,000NewHistory
AKROAkero Therapeutics, Inc.COM115,000$5.82M2.8%−245,000−68.1%ReducedHistory
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS525,000$6.04M2.9%+286,775+120.4%AddedHistory
COGTCogent Biosciences, Inc.COM650,000$6.34M3.1%+75,000+13.0%AddedHistory
PTGXProtagonist Therapeutics, IncCOM400,000$6.67M3.2%+175,000+77.8%AddedHistory
TARSTarsus Pharmaceuticals, Inc.COM400,000$7.11M3.4%+250,000+166.7%AddedHistory
PCVXVaxcyte, Inc.COM140,000$7.14M3.5%−140,000−50.0%ReducedHistory
ALPNAlpine Immune Sciences, Inc.COM664,132$7.60M3.7%+316,700+91.2%AddedHistory
AXSMAxsome Therapeutics, Inc.COM110,000$7.69M3.7%00.0%UnchangedHistory
ASNDAscendis Pharma A/SSPONSORED ADR85,000$7.96M3.9%−15,000−15.0%ReducedHistory
TGTXTG Therapeutics, Inc.COM1,000,000$8.36M4.0%+175,000+21.2%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM57,500$8.40M4.1%+2,500+4.5%AddedHistory
KRYSKrystal Biotech, Inc.COM80,000$9.28M4.5%+60,000+300.0%AddedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD330,000$18.8M9.1%00.0%UnchangedHistory

Options (11)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ghost Tree Capital, LLC in Q3 2023
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF–$21.9M
SRPTSarepta Therapeutics, Inc.COM–$18.2M
MLTXMoonLake ImmunotherapeuticsCLASS A ORD$14.3M–
AKROAkero Therapeutics, Inc.COM–$12.6M
APLSApellis Pharmaceuticals, Inc.COM–$7.04M
RCKTRocket Pharmaceuticals, Inc.COM–$6.04M
SNDXSyndax Pharmaceuticals IncCOM$4.36M–
REPLReplimune Group, Inc.COM–$4.28M
CBAYCymaBay Therapeutics, Inc.COM–$3.55M
IMVTImmunovant, Inc.COM$3.26M–
SLRNACELYRIN, Inc.COM$2.03M–

Sold out since Q2 2023 (14)

Positions held at the end of Q2 2023 that are gone from this filing.

Positions of Ghost Tree Capital, LLC sold out since Q2 2023
SecurityClassShares in Q2 2023Value in Q2 2023% of portfolio in Q2 2023History
APLSApellis Pharmaceuticals, Inc.COM180,000$16.4M5.9%History
RETAReata Pharmaceuticals IncCL A85,000$8.67M3.1%History
INCYIncyte CorpCOM65,000$4.05M1.5%History
ONCBeOne Medicines Ltd.ADR22,500$4.01M1.4%History
VIRVir Biotechnology, Inc.COM150,000$3.68M1.3%History
RCKTRocket Pharmaceuticals, Inc.COM75,000$1.49M0.5%History
BCRXBiocryst Pharmaceuticals IncCOM200,000$1.41M0.5%History
MORFMorphic Holding, Inc.COM20,000$1.15M0.4%History
SWTXSpringWorks Therapeutics, Inc.COM27,578$723.1K0.3%History
IOVAIovance Biotherapeutics, Inc.COM100,000$704.0K0.3%History
PTCTPTC Therapeutics, Inc.COM16,675$678.2K0.2%History
REPLReplimune Group, Inc.COM10,865$252.3K0.1%History
VNDAVanda Pharmaceuticals Inc.COM31,000$204.3K0.1%History
KYNBKyntra Bio, Inc.COM36,500$98.5K<0.1%History