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Ghost Tree Capital, LLC

SEC CIK
0001595851
Latest filing
Nov 14, 2024

Holdings in Q2 2023

Holdings as of Jun 30, 2023, filed Aug 14, 2023. Long positions only; changes compare share counts with Q1 2023.

Institution overview
Positions
55
+3 vs. Q1 2023
Portfolio value
$277.1M
+$12.8M (+4.8%) vs. Q1 2023
Filed
Aug 14, 2023
SEC
Holdings of Ghost Tree Capital, LLC in Q2 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
TGTXTG Therapeutics, Inc.COM825,000$20.5M7.4%−275,000−25.0%ReducedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD330,000$16.8M6.1%+135,000+69.2%AddedHistory
AKROAkero Therapeutics, Inc.COM360,000$16.8M6.1%+85,000+30.9%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM180,000$16.4M5.9%+15,380+9.3%AddedHistory
PCVXVaxcyte, Inc.COM280,000$14.0M5.0%+55,000+24.4%AddedHistory
RVNCRevance Therapeutics, Inc.COM525,000$13.3M4.8%+275,000+110.0%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM55,000$12.7M4.6%+25,000+83.3%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM550,000$11.9M4.3%+75,000+15.8%AddedHistory
VKTXViking Therapeutics, Inc.COM650,000$10.5M3.8%+50,000+8.3%AddedHistory
SRPTSarepta Therapeutics, Inc.COM85,000$9.73M3.5%+25,000+41.7%AddedHistory
ASNDAscendis Pharma A/SSPONSORED ADR100,000$8.93M3.2%−10,000−9.1%ReducedHistory
RETAReata Pharmaceuticals IncCL A85,000$8.67M3.1%+15,000+21.4%AddedHistory
AXSMAxsome Therapeutics, Inc.COM110,000$7.90M2.9%−115,000−51.1%ReducedHistory
SNDXSyndax Pharmaceuticals IncCOM350,000$7.33M2.6%+25,000+7.7%AddedHistory
MRTXMirati Therapeutics, Inc.COM200,000$7.23M2.6%+60,000+42.9%AddedHistory
XENEXenon Pharmaceuticals Inc.COM185,000$7.12M2.6%−15,000−7.5%ReducedHistory
COGTCogent Biosciences, Inc.COM575,000$6.81M2.5%+25,000+4.5%AddedHistory
PTGXProtagonist Therapeutics, IncCOM225,000$6.21M2.2%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM240,000$5.71M2.1%+65,000+37.1%AddedHistory
BMEABiomea Fusion, Inc.COM190,000$4.17M1.5%+70,000+58.3%AddedHistory
INCYIncyte CorpCOM65,000$4.05M1.5%−10,000−13.3%ReducedHistory
ONCBeOne Medicines Ltd.ADR22,500$4.01M1.4%+22,500NewHistory
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS238,225$3.92M1.4%−11,775−4.7%ReducedHistory
VIRVir Biotechnology, Inc.COM150,000$3.68M1.3%+150,000NewHistory
ALPNAlpine Immune Sciences, Inc.COM347,432$3.57M1.3%+147,432+73.7%AddedHistory
JBIOJade Biosciences, Inc.COM201,197$3.45M1.2%+1,197+0.6%AddedHistory
ZNTLZentalis Pharmaceuticals, Inc.COM100,000$2.82M1.0%+100,000NewHistory
KRTXKaruna Therapeutics, Inc.COM12,500$2.71M1.0%−5,000−28.6%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM150,000$2.71M1.0%+70,000+87.5%AddedHistory
FOLDAmicus Therapeutics, Inc.COM200,000$2.51M0.9%−275,000−57.9%ReducedHistory
ATXSAstria Therapeutics, Inc.COM300,173$2.50M0.9%−149,827−33.3%ReducedHistory
QUREuniQure N.V.SHS215,000$2.46M0.9%−160,000−42.7%ReducedHistory
KRYSKrystal Biotech, Inc.COM20,000$2.35M0.8%+20,000NewHistory
VRNAVerona Pharma plcSPONSORED ADS110,000$2.33M0.8%+110,000NewHistory
PHATPhathom Pharmaceuticals, Inc.COM154,250$2.21M0.8%+154,250NewHistory
FUSNFusion Pharmaceuticals Inc.COM412,699$1.93M0.7%+62,699+17.9%AddedHistory
IMGNImmunoGen, Inc.COM100,000$1.89M0.7%−24,977−20.0%ReducedHistory
PMVPPMV Pharmaceuticals, Inc.COM280,981$1.76M0.6%+280,981NewHistory
WHWKWhitehawk Therapeutics, Inc.COM250,000$1.71M0.6%+100,000+66.7%AddedHistory
RCUSArcus Biosciences, Inc.COM75,000$1.52M0.5%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM75,000$1.49M0.5%+75,000NewHistory
BCRXBiocryst Pharmaceuticals IncCOM200,000$1.41M0.5%−75,000−27.3%ReducedHistory
MORFMorphic Holding, Inc.COM20,000$1.15M0.4%+20,000NewHistory
INBXInhibrx Biosciences, Inc.COM35,000$908.6K0.3%+35,000NewHistory
SWTXSpringWorks Therapeutics, Inc.COM27,578$723.1K0.3%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM42,000$722.4K0.3%+17,000+68.0%AddedHistory
Avidity Biosciences, Inc.05370A108COM65,000$720.9K0.3%−60,000−48.0%Reduced–
IOVAIovance Biotherapeutics, Inc.COM100,000$704.0K0.3%−900,000−90.0%ReducedHistory
PTCTPTC Therapeutics, Inc.COM16,675$678.2K0.2%+16,675NewHistory
ROIVRoivant Sciences Ltd.SHS64,000$645.1K0.2%+64,000NewHistory
Rain Oncology Inc.75082Q105COM325,000$390.0K0.1%+75,000+30.0%Added–
REPLReplimune Group, Inc.COM10,865$252.3K0.1%+10,865NewHistory
VNDAVanda Pharmaceuticals Inc.COM31,000$204.3K0.1%+18,500+148.0%AddedHistory
MRSNMersana Therapeutics, Inc.COM61,250$201.5K0.1%+61,250NewHistory
KYNBKyntra Bio, Inc.COM36,500$98.5K<0.1%+10,000+37.7%AddedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ghost Tree Capital, LLC in Q2 2023
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF–$25.0M
BTAIQBioXcel Therapeutics, Inc.COM–$865.8K

Sold out since Q1 2023 (11)

Positions held at the end of Q1 2023 that are gone from this filing.

Positions of Ghost Tree Capital, LLC sold out since Q1 2023
SecurityClassShares in Q1 2023Value in Q1 2023% of portfolio in Q1 2023History
CTICCti Biopharma CorpCOM2,000,000$8.40M3.2%History
PFEPfizer IncStock200,000$8.16M3.1%History
JNJJohnson & JohnsonStock50,000$7.75M2.9%History
ISEEIVERIC bio, Inc.COM175,000$4.26M1.6%History
ACRSAclaris Therapeutics, Inc.COM425,000$3.44M1.3%History
ETNB89bio, Inc.COM200,000$3.05M1.2%History
IRONDisc Medicine, Inc.COM100,000$2.12M0.8%History
RXDXPrometheus Biosciences, Inc.COM15,000$1.61M0.6%History
GERNGeron CorpCOM450,000$977.0K0.4%History
XFORX4 Pharmaceuticals, IncCOM850,000$740.0K0.3%History
KZRKezar Life Sciences, Inc.COM175,000$548.0K0.2%History