EcoR1 Capital, LLC
- SEC CIK
- 0001587114
- Latest filing
- Aug 14, 2026
Holdings in Q3 2025
Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.
- Positions
- 30
- −6 vs. Q2 2025
- Portfolio value
- $2.08B
- +$394.5M (+23.4%) vs. Q2 2025
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| ZYMEZymeworks Inc. | COM | 22,970,388 | $392.3M | 18.9% | 00.0% | Unchanged | History |
| ANABAnaptysbio, Inc | COM | 7,880,094 | $241.3M | 11.6% | 00.0% | Unchanged | History |
| QUREuniQure N.V. | SHS | 3,988,971 | $232.8M | 11.2% | 00.0% | Unchanged | History |
| JAZZJazz Pharmaceuticals plc | SHS USD | 1,706,469 | $224.9M | 10.8% | 00.0% | Unchanged | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 4,288,120 | $178.6M | 8.6% | 00.0% | Unchanged | History |
| CRSPCRISPR Therapeutics AG | NAMEN AKT | 1,389,276 | $90.0M | 4.3% | 00.0% | Unchanged | History |
| TNGXTango Therapeutics, Inc. | COM | 10,630,736 | $89.3M | 4.3% | 00.0% | Unchanged | History |
| ORICOric Pharmaceuticals, Inc. | COM | 6,728,116 | $80.7M | 3.9% | +5,110,048+315.8% | Added | History |
| APLSApellis Pharmaceuticals, Inc. | COM | 3,447,156 | $78.0M | 3.8% | −8,448,652−71.0% | Reduced | History |
| XNCRXencor Inc | COM | 6,144,767 | $72.1M | 3.5% | 00.0% | Unchanged | History |
| LKFTLakefront Biotherapeutics NV | SPON ADR | 1,667,119 | $57.7M | 2.8% | +630,174+60.8% | Added | History |
| IMNMImmunome Inc. | COM | 4,079,415 | $47.8M | 2.3% | 00.0% | Unchanged | History |
| ETONEton Pharmaceuticals, Inc. | COM | 2,030,544 | $44.1M | 2.1% | 00.0% | Unchanged | History |
| MBXMBX Biosciences, Inc. | COM | 2,123,604 | $37.2M | 1.8% | +973,810+84.7% | Added | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 75,000 | $34.4M | 1.7% | 00.0% | Unchanged | History |
| Avidity Biosciences, Inc.05370A108 | COM | 765,000 | $33.3M | 1.6% | +265,000+53.0% | Added | – |
| BBOTBridgeBio Oncology Therapeutics, Inc. | COM NEW | 2,823,126 | $32.7M | 1.6% | +2,823,126 | New | History |
| NGNENeurogene Inc. | COM | 1,271,342 | $22.0M | 1.1% | 00.0% | Unchanged | History |
| ALKSAlkermes plc. | SHS | 500,000 | $15.0M | 0.7% | 00.0% | Unchanged | History |
| AQSTAquestive Therapeutics, Inc. | COM | 2,625,000 | $14.7M | 0.7% | +2,625,000 | New | History |
| MTSRMetsera, Inc. | COM | 271,529 | $14.2M | 0.7% | 00.0% | Unchanged | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 550,000 | $13.3M | 0.6% | +550,000 | New | History |
| PRMEPrime Medicine, Inc. | COM | 1,543,326 | $8.55M | 0.4% | +1,543,326 | New | History |
| ATRAAtara Biotherapeutics, Inc. | COM NEW | 573,183 | $8.21M | 0.4% | 00.0% | Unchanged | History |
| KURAKura Oncology, Inc. | COM | 872,500 | $7.72M | 0.4% | −3,327,500−79.2% | Reduced | History |
| PEPGPepGen Inc. | COM | 800,000 | $3.70M | 0.2% | +800,000 | New | History |
| VYGRVoyager Therapeutics, Inc. | COM | 670,303 | $3.13M | 0.2% | −3,247,243−82.9% | Reduced | History |
| CMPSCOMPASS Pathways plc | SPONSORED ADS | 265,137 | $1.52M | 0.1% | +265,137 | New | History |
| Nuvation Bio Inc.67080N119 | *W EXP 07/07/202 | 963,333 | – | – | 00.0% | Unchanged | – |
| Surrozen, Inc.86889P117 | *W EXP 08/01/203 | 66,665 | – | – | 00.0% | Unchanged | – |
Sold out since Q2 2025 (12)
Positions held at the end of Q2 2025 that are gone from this filing.
| Security | Class | Shares in Q2 2025 | Value in Q2 2025 | % of portfolio in Q2 2025 | History |
|---|---|---|---|---|---|
| ITOSiTeos Therapeutics, Inc. | COM | 10,688,978 | $106.6M | 6.3% | History |
| JANXJanux Therapeutics, Inc. | COM | 1,469,818 | $34.0M | 2.0% | History |
| AKROAkero Therapeutics, Inc. | COM | 440,000 | $23.5M | 1.4% | History |
| VRNAVerona Pharma plc | SPONSORED ADS | 200,000 | $18.9M | 1.1% | History |
| TECXTectonic Therapeutic, Inc. | COM | 935,121 | $18.6M | 1.1% | History |
| PCRXPacira BioSciences, Inc. | COM | 457,471 | $10.9M | 0.6% | History |
| REPLReplimune Group, Inc. | COM | 850,341 | $7.90M | 0.5% | History |
| ADAPYAdaptimmune Therapeutics PLC | SPONDS ADR | 27,404,070 | $6.57M | 0.4% | History |
| DAWNDay One Biopharmaceuticals, Inc. | Stock | 862,068 | $5.60M | 0.3% | History |
| HLVXHilleVax, Inc. | COM | 2,420,243 | $4.82M | 0.3% | History |
| WHWKWhitehawk Therapeutics, Inc. | COM | 1,091,417 | $2.04M | 0.1% | History |
| MGNXMacrogenics Inc | COM | 1,602,717 | $1.94M | 0.1% | History |