Sphera Funds Management Ltd.
- SEC CIK
- 0001496201
- Latest filing
- Aug 14, 2026
Holdings in Q1 2023
Holdings as of Mar 31, 2023, filed May 15, 2023. Long positions only; changes compare share counts with Q4 2022.
- Positions
- 75
- +17 vs. Q4 2022
- Portfolio value
- $461.9M
- +$143.8M (+45.2%) vs. Q4 2022
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| SNYSanofi | SPONSORED ADR | 529,515 | $28.8M | 6.2% | −30,000−5.4% | Reduced | History |
| NICENICE Ltd. | SPONSORED ADR | 115,482 | $26.4M | 5.7% | +115,482 | New | History |
| AZNAstraZeneca PLC | SPONSORED ADR | 285,060 | $19.8M | 4.3% | −115,000−28.7% | Reduced | History |
| JNJJohnson & Johnson | Stock | 119,831 | $18.6M | 4.0% | +10,000+9.1% | Added | History |
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | 2,039,500 | $18.0M | 3.9% | +2,039,500 | New | History |
| MSFTMicrosoft Corp | Stock | 54,623 | $15.7M | 3.4% | +54,623 | New | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 683,061 | $14.4M | 3.1% | −27,500−3.9% | Reduced | History |
| MRKMerck & Co., Inc. | Stock | 120,600 | $12.8M | 2.8% | 00.0% | Unchanged | History |
| NVONovo Nordisk A S | ADR | 71,540 | $11.4M | 2.5% | 00.0% | Unchanged | History |
| Enphase Energy, Inc.29355AAK3 | NOTE 3/0 | 10,725,000 | $11.2M | 2.4% | +10,725,000 | New | – |
| LLYEli Lilly & Co | Stock | 31,690 | $10.9M | 2.4% | +6,000+23.4% | Added | History |
| NTRNutrien Ltd. | COM | 145,466 | $10.7M | 2.3% | +145,466 | New | History |
| INZYInozyme Pharma, Inc. | COM | 1,781,858 | $10.2M | 2.2% | +156,800+9.6% | Added | History |
| ABBVAbbVie Inc. | Stock | 63,000 | $10.0M | 2.2% | +3,000+5.0% | Added | History |
| BIIBBiogen Inc. | COM | 33,516 | $9.32M | 2.0% | +26,000+345.9% | Added | History |
| BBIOBridgeBio Pharma, Inc. | COM | 561,983 | $9.32M | 2.0% | +561,983 | New | History |
| AMZNAmazon Com Inc | Stock | 85,680 | $8.85M | 1.9% | +85,680 | New | History |
| Invesco QQQ Trust Series I46090E103 | ETF | 26,353 | $8.46M | 1.8% | +26,353 | New | – |
| SWTXSpringWorks Therapeutics, Inc. | COM | 317,625 | $8.18M | 1.8% | +1,000+0.3% | Added | History |
| PTCTPTC Therapeutics, Inc. | COM | 159,100 | $7.71M | 1.7% | +159,100 | New | History |
| ENLTEnlight Renewable Energy Ltd. | SHS | 450,864 | $7.63M | 1.7% | +450,864 | New | History |
| KURAKura Oncology, Inc. | COM | 603,287 | $7.38M | 1.6% | +45,000+8.1% | Added | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 183,696 | $7.37M | 1.6% | 00.0% | Unchanged | History |
| JSPRJasper Therapeutics, Inc. | COM | 4,044,008 | $7.32M | 1.6% | +4,044,008 | New | History |
| PNTPOINT Biopharma Global Inc. | COM | 952,642 | $6.93M | 1.5% | 00.0% | Unchanged | History |
| CAMTCamtek Ltd | ORD | 239,494 | $6.79M | 1.5% | +129,494+117.7% | Added | History |
| SAGESage Therapeutics, Inc. | COM | 155,000 | $6.50M | 1.4% | +155,000 | New | History |
| MRUSMerus N.V. | COM | 336,993 | $6.20M | 1.3% | +20,000+6.3% | Added | History |
| SRPTSarepta Therapeutics, Inc. | COM | 44,000 | $6.06M | 1.3% | +44,000 | New | History |
| KZRKezar Life Sciences, Inc. | COM | 1,888,228 | $5.91M | 1.3% | +583,045+44.7% | Added | History |
| Bellus Health Inc New07987C204 | COM NEW | 799,860 | $5.76M | 1.2% | +310,000+63.3% | Added | – |
| PFEPfizer Inc | Stock | 140,000 | $5.71M | 1.2% | +140,000 | New | History |
| ISEEIVERIC bio, Inc. | COM | 231,591 | $5.63M | 1.2% | +36,000+18.4% | Added | History |
| ATXSAstria Therapeutics, Inc. | COM | 421,018 | $5.60M | 1.2% | −48,322−10.3% | Reduced | History |
| NVSNovartis AG | ADR | 60,000 | $5.52M | 1.2% | +60,000 | New | History |
| IMTXImmatics N.V. | SHS | 780,852 | $5.39M | 1.2% | 00.0% | Unchanged | History |
| MLYSMineralys Therapeutics, Inc. | COM | 339,000 | $5.31M | 1.1% | +339,000 | New | History |
| ACLXArcellx, Inc. | COMMON STOCK | 167,488 | $5.16M | 1.1% | −70,000−29.5% | Reduced | History |
| PERIPerion Network Ltd. | SHS NEW | 130,000 | $5.15M | 1.1% | +130,000 | New | History |
| KNSAKiniksa Pharmaceuticals International, plc | COM CL A | 450,283 | $4.85M | 1.0% | +143,000+46.5% | Added | History |
| FUSNFusion Pharmaceuticals Inc. | COM | 1,283,537 | $4.84M | 1.0% | +1,283,537 | New | History |
| IRONDisc Medicine, Inc. | COM | 220,013 | $4.66M | 1.0% | +220,013 | New | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 19,000 | $4.60M | 1.0% | +19,000 | New | History |
| Gracell Biotechnologies Inc38406L103 | SPONSORED ADS | 2,360,580 | $4.39M | 1.0% | +2,360,580 | New | – |
| TVTXTravere Therapeutics, Inc. | COM | 187,500 | $4.22M | 0.9% | +187,500 | New | History |
| RCKTRocket Pharmaceuticals, Inc. | COM | 236,000 | $4.04M | 0.9% | +236,000 | New | History |
| PANWPalo Alto Networks Inc | Stock | 20,000 | $3.99M | 0.9% | +20,000 | New | History |
| PCVXVaxcyte, Inc. | COM | 90,000 | $3.37M | 0.7% | +90,000 | New | History |
| COGTCogent Biosciences, Inc. | COM | 300,000 | $3.24M | 0.7% | +300,000 | New | History |
| RNACCartesian Therapeutics, Inc. | COM | 2,325,000 | $3.23M | 0.7% | +2,325,000 | New | History |
| MIRMMirum Pharmaceuticals, Inc. | COM | 109,336 | $2.63M | 0.6% | +109,336 | New | History |
| DYNDyne Therapeutics, Inc. | COM | 219,316 | $2.53M | 0.5% | +212,167+2,967.8% | Added | History |
| RIGLRigel Pharmaceuticals Inc | COM NEW | 1,878,845 | $2.48M | 0.5% | −400,000−17.6% | Reduced | History |
| AMGNAmgen Inc | Stock | 10,000 | $2.42M | 0.5% | +10,000 | New | History |
| RZLTRezolute, Inc. | COM NEW | 1,155,897 | $2.22M | 0.5% | 00.0% | Unchanged | History |
| KDNYChinook Therapeutics, Inc. | COM | 92,200 | $2.13M | 0.5% | −35,000−27.5% | Reduced | History |
| HOWLWerewolf Therapeutics, Inc. | COM | 626,810 | $1.63M | 0.4% | 00.0% | Unchanged | History |
| ALPNAlpine Immune Sciences, Inc. | COM | 200,000 | $1.54M | 0.3% | 00.0% | Unchanged | History |
| MDWDMediWound Ltd. | SHS NEW | 111,127 | $1.48M | 0.3% | +35,714+47.4% | Added | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 82,747 | $1.33M | 0.3% | −588,897−87.7% | Reduced | History |
| KROSKeros Therapeutics, Inc. | COM | 30,119 | $1.29M | 0.3% | −128,638−81.0% | Reduced | History |
| ALTAltimmune, Inc. | COM NEW | 300,000 | $1.27M | 0.3% | −80,298−21.1% | Reduced | History |
| QUREuniQure N.V. | SHS | 62,000 | $1.25M | 0.3% | +62,000 | New | History |
| ANNXAnnexon, Inc. | COM | 250,000 | $962.5K | 0.2% | +250,000 | New | History |
| PMVPPMV Pharmaceuticals, Inc. | COM | 187,800 | $895.8K | 0.2% | 00.0% | Unchanged | History |
| RETAReata Pharmaceuticals Inc | CL A | 7,689 | $699.1K | 0.2% | +7,689 | New | History |
| INFIInfinity Pharmaceuticals, Inc. | COM | 1,476,000 | $236.2K | 0.1% | 00.0% | Unchanged | History |
| Fiverr Intl Ltd33835LAA3 | NOTE 11/0 | 250,000 | $208.2K | <0.1% | −4,701,000−95.0% | Reduced | – |
| SYRESpyre Therapeutics, Inc. | COM | 646,478 | $187.5K | <0.1% | +205,641+46.6% | Added | History |
| OTMOOtonomo Technologies Ltd. | ORDINARY SHARES | 391,863 | $186.4K | <0.1% | 00.0% | Unchanged | History |
| ONCROncorus, Inc. | COM | 540,258 | $185.9K | <0.1% | 00.0% | Unchanged | History |
| Immatics N.V.N44445117 | *W EXP 07/01/202 | 100,000 | $144.0K | <0.1% | 00.0% | Unchanged | – |
| Bio Green Med Solution, Inc.23254L603 | COM | 250,000 | $142.6K | <0.1% | 00.0% | Unchanged | – |
| ARBEArbe Robotics Ltd. | COM | 43,165 | $137.7K | <0.1% | 00.0% | Unchanged | History |
| MRSNMersana Therapeutics, Inc. | COM | 10,621 | $43.7K | <0.1% | +10,621 | New | History |
Options (6)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| iShares Russell 2000 ETF464287655 | ETF | $75.1M | – |
| SPYSPDR S&P 500 ETF Trust | ETF | $30.7M | – |
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | – | $18.0M |
| State Street Industrial Select Sector SPDR ETF81369Y704 | ETF | $5.84M | – |
| QUREuniQure N.V. | SHS | – | $3.53M |
| BBIOBridgeBio Pharma, Inc. | COM | – | $3.32M |
Sold out since Q4 2022 (16)
Positions held at the end of Q4 2022 that are gone from this filing.
| Security | Class | Shares in Q4 2022 | Value in Q4 2022 | % of portfolio in Q4 2022 | History |
|---|---|---|---|---|---|
| ALBOAlbireo Pharma, Inc. | COM | 463,828 | $10.0M | 3.2% | History |
| CINCCinCor Pharma, Inc. | COM | 529,640 | $6.51M | 2.0% | History |
| FIVNFive9, Inc. | COM | 95,000 | $6.45M | 2.0% | History |
| CNCEConcert Pharmaceuticals, Inc. | COM | 1,002,783 | $5.86M | 1.8% | History |
| State Street SPDR S&P Biotech ETF78464A870 | ETF | 70,000 | $5.81M | 1.8% | – |
| GNRCGenerac Holdings Inc. | Stock | 50,000 | $5.03M | 1.6% | History |
| DRSLeonardo DRS, Inc. | Stock | 335,557 | $4.29M | 1.3% | History |
| ETNB89bio, Inc. | COM | 180,600 | $2.30M | 0.7% | History |
| STOKStoke Therapeutics, Inc. | COM | 188,640 | $1.74M | 0.5% | History |
| BCABBioAtla, Inc. | COM | 186,600 | $1.54M | 0.5% | History |
| AUTLAutolus Therapeutics plc | SPON ADS | 500,000 | $950.0K | 0.3% | History |
| AMATApplied Materials Inc | Stock | 8,499 | $827.6K | 0.3% | History |
| Nice Sys Inc65366HAB9 | NOTE 1.250% 1/1 | 250,000 | $576.5K | 0.2% | – |
| TBLATaboola.com Ltd. | ORD SHS | 120,000 | $369.6K | 0.1% | History |
| Magic Software Enterprises L559166103 | ORD | 21,981 | $352.2K | 0.1% | – |
| TEADTeads Holding Co. | COM | 12,148 | $44.0K | <0.1% | History |