Sphera Funds Management Ltd.
- SEC CIK
- 0001496201
- Latest filing
- Aug 14, 2026
Holdings in Q4 2022
Holdings as of Dec 31, 2022, filed Feb 14, 2023. Long positions only; changes compare share counts with Q3 2022.
- Positions
- 58
- −7 vs. Q3 2022
- Portfolio value
- $318.1M
- −$246.5M (−43.7%) vs. Q3 2022
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| AZNAstraZeneca PLC | SPONSORED ADR | 400,060 | $27.1M | 8.5% | −497,000−55.4% | Reduced | History |
| SNYSanofi | SPONSORED ADR | 559,515 | $27.1M | 8.5% | −655,000−53.9% | Reduced | History |
| JNJJohnson & Johnson | Stock | 109,831 | $19.4M | 6.1% | −106,320−49.2% | Reduced | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 710,561 | $18.1M | 5.7% | −112,135−13.6% | Reduced | History |
| MRKMerck & Co., Inc. | Stock | 120,600 | $13.4M | 4.2% | −246,400−67.1% | Reduced | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 671,644 | $12.3M | 3.9% | +45,092+7.2% | Added | History |
| ALBOAlbireo Pharma, Inc. | COM | 463,828 | $10.0M | 3.2% | +104,828+29.2% | Added | History |
| ABBVAbbVie Inc. | Stock | 60,000 | $9.70M | 3.0% | −102,285−63.0% | Reduced | History |
| NVONovo Nordisk A S | ADR | 71,540 | $9.68M | 3.0% | −224,900−75.9% | Reduced | History |
| LLYEli Lilly & Co | Stock | 25,690 | $9.40M | 3.0% | −117,860−82.1% | Reduced | History |
| KZRKezar Life Sciences, Inc. | COM | 1,305,183 | $9.19M | 2.9% | +59,377+4.8% | Added | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 183,696 | $8.51M | 2.7% | +10,000+5.8% | Added | History |
| SWTXSpringWorks Therapeutics, Inc. | COM | 316,625 | $8.24M | 2.6% | +15,000+5.0% | Added | History |
| KROSKeros Therapeutics, Inc. | COM | 158,757 | $7.62M | 2.4% | −48,062−23.2% | Reduced | History |
| ACLXArcellx, Inc. | COMMON STOCK | 237,488 | $7.36M | 2.3% | −96,592−28.9% | Reduced | History |
| ATXSAstria Therapeutics, Inc. | COM | 469,340 | $6.99M | 2.2% | +469,340 | New | History |
| PNTPOINT Biopharma Global Inc. | COM | 952,642 | $6.94M | 2.2% | −100,200−9.5% | Reduced | History |
| KURAKura Oncology, Inc. | COM | 558,287 | $6.93M | 2.2% | −231,665−29.3% | Reduced | History |
| IMTXImmatics N.V. | SHS | 780,852 | $6.80M | 2.1% | −14,554−1.8% | Reduced | History |
| CINCCinCor Pharma, Inc. | COM | 529,640 | $6.51M | 2.0% | +410,690+345.3% | Added | History |
| FIVNFive9, Inc. | COM | 95,000 | $6.45M | 2.0% | +95,000 | New | History |
| ALTAltimmune, Inc. | COM NEW | 380,298 | $6.26M | 2.0% | −220,000−36.6% | Reduced | History |
| CNCEConcert Pharmaceuticals, Inc. | COM | 1,002,783 | $5.86M | 1.8% | +50,000+5.2% | Added | History |
| State Street SPDR S&P Biotech ETF78464A870 | ETF | 70,000 | $5.81M | 1.8% | +70,000 | New | – |
| GNRCGenerac Holdings Inc. | Stock | 50,000 | $5.03M | 1.6% | +50,000 | New | History |
| MRUSMerus N.V. | COM | 316,993 | $4.90M | 1.5% | +3,667+1.2% | Added | History |
| KNSAKiniksa Pharmaceuticals International, plc | COM CL A | 307,283 | $4.60M | 1.4% | +307,283 | New | History |
| DRSLeonardo DRS, Inc. | Stock | 335,557 | $4.29M | 1.3% | +335,557 | New | History |
| ISEEIVERIC bio, Inc. | COM | 195,591 | $4.19M | 1.3% | −386,238−66.4% | Reduced | History |
| Bellus Health Inc New07987C204 | COM NEW | 489,860 | $4.03M | 1.3% | +25,000+5.4% | Added | – |
| Fiverr Intl Ltd33835LAA3 | NOTE 11/0 | 4,951,000 | $4.01M | 1.3% | 00.0% | Unchanged | – |
| RIGLRigel Pharmaceuticals Inc | COM NEW | 2,278,845 | $3.42M | 1.1% | +116,259+5.4% | Added | History |
| KDNYChinook Therapeutics, Inc. | COM | 127,200 | $3.33M | 1.0% | −407,158−76.2% | Reduced | History |
| CAMTCamtek Ltd | ORD | 110,000 | $2.42M | 0.8% | +110,000 | New | History |
| RZLTRezolute, Inc. | COM NEW | 1,155,897 | $2.39M | 0.8% | 00.0% | Unchanged | History |
| ETNB89bio, Inc. | COM | 180,600 | $2.30M | 0.7% | −478,184−72.6% | Reduced | History |
| BIIBBiogen Inc. | COM | 7,516 | $2.08M | 0.7% | −47,984−86.5% | Reduced | History |
| STOKStoke Therapeutics, Inc. | COM | 188,640 | $1.74M | 0.5% | +31,440+20.0% | Added | History |
| INZYInozyme Pharma, Inc. | COM | 1,625,058 | $1.71M | 0.5% | +450,000+38.3% | Added | History |
| PMVPPMV Pharmaceuticals, Inc. | COM | 187,800 | $1.63M | 0.5% | 00.0% | Unchanged | History |
| BCABBioAtla, Inc. | COM | 186,600 | $1.54M | 0.5% | +186,600 | New | History |
| ALPNAlpine Immune Sciences, Inc. | COM | 200,000 | $1.47M | 0.5% | 00.0% | Unchanged | History |
| HOWLWerewolf Therapeutics, Inc. | COM | 626,810 | $1.28M | 0.4% | 00.0% | Unchanged | History |
| MDWDMediWound Ltd. | SHS NEW | 75,413 | $1.02M | 0.3% | −22,975−23.4% | ReducedConverted for a 1-for-7 split | History |
| AUTLAutolus Therapeutics plc | SPON ADS | 500,000 | $950.0K | 0.3% | +500,000 | New | History |
| AMATApplied Materials Inc | Stock | 8,499 | $827.6K | 0.3% | +8,499 | New | History |
| INFIInfinity Pharmaceuticals, Inc. | COM | 1,476,000 | $819.2K | 0.3% | 00.0% | Unchanged | History |
| Nice Sys Inc65366HAB9 | NOTE 1.250% 1/1 | 250,000 | $576.5K | 0.2% | 00.0% | Unchanged | – |
| TBLATaboola.com Ltd. | ORD SHS | 120,000 | $369.6K | 0.1% | +120,000 | New | History |
| Magic Software Enterprises L559166103 | ORD | 21,981 | $352.2K | 0.1% | −59,312−73.0% | Reduced | – |
| Immatics N.V.N44445117 | *W EXP 07/01/202 | 100,000 | $251.0K | 0.1% | 00.0% | Unchanged | – |
| SYRESpyre Therapeutics, Inc. | COM | 440,837 | $198.3K | 0.1% | +440,837 | New | History |
| Bio Green Med Solution, Inc.23254L603 | COM | 250,000 | $166.8K | 0.1% | 00.0% | Unchanged | – |
| OTMOOtonomo Technologies Ltd. | ORDINARY SHARES | 391,863 | $159.5K | 0.1% | 00.0% | Unchanged | History |
| ARBEArbe Robotics Ltd. | COM | 43,165 | $147.2K | <0.1% | 00.0% | Unchanged | History |
| ONCROncorus, Inc. | COM | 540,258 | $136.8K | <0.1% | 00.0% | Unchanged | History |
| DYNDyne Therapeutics, Inc. | COM | 7,149 | $82.9K | <0.1% | +7,149 | New | History |
| TEADTeads Holding Co. | COM | 12,148 | $44.0K | <0.1% | +12,148 | New | History |
Options (6)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| Invesco QQQ Tr46090E903 | UNIT SER 1 | – | $61.5M |
| Invesco QQQ Tr46090E953 | PUT | $55.9M | – |
| Teva Pharmaceutical Inds Ltd881624909 | CALL | – | $20.3M |
| Tower Semiconductor LtdM87915954 | PUT | $6.98M | – |
| Apellis Pharmaceuticals Inc03753U956 | PUT | $3.10M | – |
| 89BIO Inc282559903 | CALL | – | $45.8K |
Sold out since Q3 2022 (21)
Positions held at the end of Q3 2022 that are gone from this filing.
| Security | Class | Shares in Q3 2022 | Value in Q3 2022 | % of portfolio in Q3 2022 | History |
|---|---|---|---|---|---|
| PANWPalo Alto Networks Inc | Stock | 63,000 | $10.3M | 1.8% | History |
| WIXWix.com Ltd. | SHS | 129,000 | $10.1M | 1.8% | History |
| KRNTKornit Digital Ltd. | SHS | 322,926 | $8.59M | 1.5% | History |
| GLBEGlobal-E Online Ltd. | SHS | 311,460 | $8.34M | 1.5% | History |
| ADBEAdobe Inc. | Stock | 29,150 | $8.02M | 1.4% | History |
| PERIPerion Network Ltd. | SHS NEW | 405,184 | $7.82M | 1.4% | History |
| SSentinelOne, Inc. | CL A | 280,000 | $7.16M | 1.3% | History |
| RLMDRelmada Therapeutics, Inc. | COM | 193,230 | $7.15M | 1.3% | History |
| SEDGSolaredge Technologies, Inc. | COM | 29,426 | $6.81M | 1.2% | History |
| GILDGilead Sciences, Inc. | Stock | 105,090 | $6.48M | 1.1% | History |
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | 776,346 | $6.26M | 1.1% | History |
| NVDANVIDIA Corp | Stock | 40,000 | $4.86M | 0.9% | History |
| DICEDICE Therapeutics, Inc. | COM | 152,913 | $3.10M | 0.5% | History |
| RUNSunrun Inc. | COM | 65,000 | $1.79M | 0.3% | History |
| VRNAVerona Pharma plc | SPONSORED ADS | 120,000 | $1.23M | 0.2% | History |
| PSTXPoseida Therapeutics, Inc. | COM | 300,000 | $1.06M | 0.2% | History |
| ICLICL Group Ltd. | SHS | 111,482 | $912.0K | 0.2% | History |
| NICENICE Ltd. | SPONSORED ADR | 3,145 | $592.0K | 0.1% | History |
| Wix.com Ltd.92940WAD1 | NOTE 8/1 | 700,000 | $591.0K | 0.1% | – |
| EWTXEdgewise Therapeutics, Inc. | COM | 60,000 | $590.0K | 0.1% | History |
| UUnity Software Inc. | COM | 11,500 | $366.0K | 0.1% | History |