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Sphera Funds Management Ltd.

SEC CIK
0001496201
Latest filing
Aug 14, 2026

Holdings in Q3 2022

Holdings as of Sep 30, 2022, filed Nov 14, 2022. Long positions only; changes compare share counts with Q2 2022.

Institution overview
Positions
65
+15 vs. Q2 2022
Portfolio value
$564.7M
+$37.8M (+7.2%) vs. Q2 2022
Filed
Nov 14, 2022
SEC
Holdings of Sphera Funds Management Ltd. in Q3 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
AZNAstraZeneca PLCSPONSORED ADR897,060$49.2M8.7%+98,450+12.3%AddedHistory
LLYEli Lilly & CoStock143,550$46.4M8.2%+11,300+8.5%AddedHistory
SNYSanofiSPONSORED ADR1,214,515$46.2M8.2%+368,300+43.5%AddedHistory
JNJJohnson & JohnsonStock216,151$35.3M6.3%−60,300−21.8%ReducedHistory
MRKMerck & Co., Inc.Stock367,000$31.6M5.6%+82,000+28.8%AddedHistory
NVONovo Nordisk A SADR296,440$29.5M5.2%+35,000+13.4%AddedHistory
ABBVAbbVie Inc.Stock162,285$21.8M3.9%−56,100−25.7%ReducedHistory
SNDXSyndax Pharmaceuticals IncCOM822,696$19.8M3.5%−316,633−27.8%ReducedHistory
BIIBBiogen Inc.COM55,500$14.8M2.6%+55,500NewHistory
CRNXCrinetics Pharmaceuticals, Inc.COM626,552$12.3M2.2%+39,732+6.8%AddedHistory
KURAKura Oncology, Inc.COM789,952$10.8M1.9%+295,357+59.7%AddedHistory
KZRKezar Life Sciences, Inc.COM1,245,806$10.7M1.9%+946,152+315.7%AddedHistory
KDNYChinook Therapeutics, Inc.COM534,358$10.5M1.9%−109,373−17.0%ReducedHistory
ISEEIVERIC bio, Inc.COM581,829$10.4M1.8%−380,641−39.5%ReducedHistory
PANWPalo Alto Networks IncStock63,000$10.3M1.8%+63,000NewHistory
WIXWix.com Ltd.SHS129,000$10.1M1.8%+129,000NewHistory
SWTXSpringWorks Therapeutics, Inc.COM301,625$8.61M1.5%−235,039−43.8%ReducedHistory
KRNTKornit Digital Ltd.SHS322,926$8.59M1.5%+322,926NewHistory
GLBEGlobal-E Online Ltd.SHS311,460$8.34M1.5%+311,460NewHistory
PNTPOINT Biopharma Global Inc.COM1,052,842$8.14M1.4%+1,052,842NewHistory
ADBEAdobe Inc.Stock29,150$8.02M1.4%+29,150NewHistory
IMTXImmatics N.V.SHS795,406$7.95M1.4%+64,694+8.9%AddedHistory
PERIPerion Network Ltd.SHS NEW405,184$7.82M1.4%+405,184NewHistory
KROSKeros Therapeutics, Inc.COM206,819$7.78M1.4%+138,822+204.2%AddedHistory
ALTAltimmune, Inc.COM NEW600,298$7.67M1.4%−792,586−56.9%ReducedHistory
RAREUltragenyx Pharmaceutical Inc.COM173,696$7.19M1.3%+173,696NewHistory
SSentinelOne, Inc.CL A280,000$7.16M1.3%+280,000NewHistory
RLMDRelmada Therapeutics, Inc.COM193,230$7.15M1.3%−273,600−58.6%ReducedHistory
ALBOAlbireo Pharma, Inc.COM359,000$6.95M1.2%+359,000NewHistory
SEDGSolaredge Technologies, Inc.COM29,426$6.81M1.2%+29,426NewHistory
GILDGilead Sciences, Inc.Stock105,090$6.48M1.1%+105,090NewHistory
CNCEConcert Pharmaceuticals, Inc.COM952,783$6.38M1.1%+273,383+40.2%AddedHistory
MRUSMerus N.V.COM313,326$6.28M1.1%−95,835−23.4%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK334,080$6.27M1.1%+334,080NewHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS776,346$6.26M1.1%−371,532−32.4%ReducedHistory
Bellus Health Inc New07987C204COM NEW464,860$4.91M0.9%+464,860New–
NVDANVIDIA CorpStock40,000$4.86M0.9%+28,712+254.4%AddedHistory
CINCCinCor Pharma, Inc.COM118,950$3.90M0.7%+118,950NewHistory
Fiverr Intl Ltd33835LAA3NOTE 11/04,951,000$3.90M0.7%00.0%Unchanged–
ETNB89bio, Inc.COM658,784$3.81M0.7%+208,784+46.4%AddedHistory
RZLTRezolute, Inc.COM NEW1,155,897$3.17M0.6%00.0%UnchangedHistory
INZYInozyme Pharma, Inc.COM1,175,058$3.15M0.6%+9,458+0.8%AddedHistory
DICEDICE Therapeutics, Inc.COM152,913$3.10M0.5%+152,913NewHistory
HOWLWerewolf Therapeutics, Inc.COM626,810$2.83M0.5%+29,807+5.0%AddedHistory
RIGLRigel Pharmaceuticals IncCOM NEW2,162,586$2.55M0.5%−362,414−14.4%ReducedHistory
PMVPPMV Pharmaceuticals, Inc.COM187,800$2.23M0.4%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM157,200$2.02M0.4%+157,200NewHistory
RUNSunrun Inc.COM65,000$1.79M0.3%+65,000NewHistory
INFIInfinity Pharmaceuticals, Inc.COM1,476,000$1.76M0.3%+1,476,000NewHistory
ALPNAlpine Immune Sciences, Inc.COM200,000$1.44M0.3%+200,000NewHistory
Magic Software Enterprises L559166103ORD81,293$1.26M0.2%00.0%Unchanged–
VRNAVerona Pharma plcSPONSORED ADS120,000$1.23M0.2%+120,000NewHistory
PSTXPoseida Therapeutics, Inc.COM300,000$1.06M0.2%+300,000NewHistory
MDWDMediWound Ltd.ORD SHS688,716$958.0K0.2%+688,716NewHistory
ICLICL Group Ltd.SHS111,482$912.0K0.2%+111,482NewHistory
NICENICE Ltd.SPONSORED ADR3,145$592.0K0.1%−52,337−94.3%ReducedHistory
Wix.com Ltd.92940WAD1NOTE 8/1700,000$591.0K0.1%00.0%Unchanged–
EWTXEdgewise Therapeutics, Inc.COM60,000$590.0K0.1%+60,000NewHistory
Nice Sys Inc65366HAB9NOTE 1.250% 1/1250,000$571.0K0.1%00.0%Unchanged–
ONCROncorus, Inc.COM540,258$459.0K0.1%00.0%UnchangedHistory
UUnity Software Inc.COM11,500$366.0K0.1%+11,500NewHistory
Bio Green Med Solution, Inc.23254L603COM250,000$365.0K0.1%+250,000New–
Immatics N.V.N44445117*W EXP 07/01/202100,000$271.0K<0.1%00.0%Unchanged–
ARBEArbe Robotics Ltd.COM43,165$259.0K<0.1%00.0%UnchangedHistory
OTMOOtonomo Technologies Ltd.ORDINARY SHARES391,863$111.0K<0.1%00.0%UnchangedHistory

Options (9)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Sphera Funds Management Ltd. in Q3 2022
SecurityClassPutsCalls
Invesco QQQ Tr46090E953PUT$87.0M–
NVIDIA Corporation67066G904CALL–$21.0M
Teva Pharmaceutical Inds Ltd881624909CALL–$17.8M
Unity Software Inc91332U901CALL–$11.7M
Generac Hldgs Inc368736904CALL–$6.34M
Sentinelone Inc81730H909CALL–$4.21M
Relmada Therapeutics Inc75955J952PUT$3.44M–
Dice Therapeutics Inc23345J954PUT$3.04M–
Altimmune Inc02155H950COM NEW$1.28M–

Sold out since Q2 2022 (13)

Positions held at the end of Q2 2022 that are gone from this filing.

Positions of Sphera Funds Management Ltd. sold out since Q2 2022
SecurityClassShares in Q2 2022Value in Q2 2022% of portfolio in Q2 2022History
State Street SPDR S&P Biotech ETF78464A870ETF437,748$32.5M6.2%–
FIVNFive9, Inc.COM140,968$12.8M2.4%History
FOLDAmicus Therapeutics, Inc.COM753,037$8.09M1.5%History
METAMeta Platforms, Inc.Stock50,000$8.06M1.5%History
CCCCC4 Therapeutics, Inc.COM STK705,736$5.32M1.0%History
VTGNVistagen Therapeutics, Inc.COM NEW3,291,135$2.90M0.5%History
VVisa Inc.Stock12,600$2.48M0.5%History
ABNBAirbnb, Inc.Stock27,700$2.47M0.5%History
Invesco QQQ Trust Series I46090E103ETF8,186$2.29M0.4%–
AMDAdvanced Micro Devices IncStock15,773$1.21M0.2%History
KNTEKinnate Biopharma Inc.COM91,673$1.16M0.2%History
GNRCGenerac Holdings Inc.Stock2,310$486.0K0.1%History
VINCVincerx Pharma, Inc.COM NEW70,467$93.0K<0.1%History