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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q4 2024

Holdings as of Dec 31, 2024, filed Feb 14, 2025. Long positions only; changes compare share counts with Q3 2024.

Institution overview
Positions
26
−3 vs. Q3 2024
Portfolio value
$212.2M
−$119.2M (−36.0%) vs. Q3 2024
Filed
Feb 14, 2025
SEC
Holdings of Great Point Partners LLC in Q4 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
IONSIonis Pharmaceuticals IncCOM505,007$17.7M8.3%+250,007+98.0%AddedHistory
CYTKCytokinetics IncCOM NEW360,000$16.9M8.0%+44,000+13.9%AddedHistory
KALVKalVista Pharmaceuticals, Inc.COM1,787,003$15.1M7.1%+487,500+37.5%AddedHistory
VRDNViridian Therapeutics, Inc.COM750,000$14.4M6.8%00.0%UnchangedHistory
PLRXPliant Therapeutics, Inc.COM1,055,000$13.9M6.5%−855,121−44.8%ReducedHistory
ABVXAbivax S.A.SPONSORED ADS1,648,523$12.1M5.7%−480,250−22.6%ReducedHistory
DVAXDynavax Technologies CorpCOM NEW860,000$11.0M5.2%−466,234−35.2%ReducedHistory
NGNENeurogene Inc.COM442,761$10.1M4.8%−561,530−55.9%ReducedHistory
EOLSEvolus, Inc.COM895,524$9.89M4.7%−274,476−23.5%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM245,272$9.61M4.5%+245,272NewHistory
UNCYUnicycive Therapeutics, Inc.COM10,980,000$8.72M4.1%+2,421,000+28.3%AddedHistory
ZURAZura Bio LtdCLASS A ORD SHS3,170,194$7.93M3.7%−93,478−2.9%ReducedHistory
AUTLAutolus Therapeutics plcSPON ADS3,009,392$7.07M3.3%+197,437+7.0%AddedHistory
JSPRJasper Therapeutics, Inc.COM NEW322,380$6.89M3.2%00.0%UnchangedHistory
MRUSMerus N.V.COM158,092$6.65M3.1%−91,908−36.8%ReducedHistory
DNTHDianthus Therapeutics, Inc.COM275,000$6.00M2.8%00.0%UnchangedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.25M2.5%00.0%UnchangedHistory
UPBUpstream Bio, Inc.COM300,000$4.93M2.3%+300,000NewHistory
CNTXContext Therapeutics Inc.COM4,683,711$4.92M2.3%−2,251,271−32.5%ReducedHistory
VYGRVoyager Therapeutics, Inc.COM826,751$4.69M2.2%−133,202−13.9%ReducedHistory
ORKAOruka Therapeutics, Inc.COM228,803$4.44M2.1%−285,856−55.5%ReducedHistory
MREOMereo BioPharma Group plcSPON ADS1,150,000$4.03M1.9%+1,150,000NewHistory
RZLTRezolute, Inc.COM NEW621,894$3.05M1.4%+621,894NewHistory
PMNProMIS Neurosciences Inc.COM2,645,128$2.51M1.2%−145,570−5.2%ReducedHistory
OPTNOptiNose, Inc.COM NEW370,269$2.47M1.2%−487,140−56.8%ReducedConverted for a 1-for-15 splitHistory
URGNUroGen Pharma Ltd.COM187,843$2.00M0.9%−570,943−75.2%ReducedHistory

Sold out since Q3 2024 (7)

Positions held at the end of Q3 2024 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q3 2024
SecurityClassShares in Q3 2024Value in Q3 2024% of portfolio in Q3 2024History
OLMAOlema Pharmaceuticals, Inc.COM1,000,000$11.9M3.6%History
ACLXArcellx, Inc.COMMON STOCK100,000$8.35M2.5%History
OTLKOutlook Therapeutics, Inc.Stock1,293,028$6.90M2.1%History
TCRXTScan Therapeutics, Inc.COM1,016,375$5.06M1.5%History
RNACCartesian Therapeutics, Inc.COM NEW200,000$3.22M1.0%History
VTGNVistagen Therapeutics, Inc.COM674,075$2.03M0.6%History
CLYMClimb Bio, Inc.COM248,168$1.26M0.4%History