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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q4 2024

Holdings as of Dec 31, 2024, filed Feb 14, 2025. Long positions only; changes compare share counts with Q3 2024.

Institution overview
Positions
26
−3 vs. Q3 2024
Portfolio value
$212.2M
−$119.2M (−36.0%) vs. Q3 2024
Filed
Feb 14, 2025
SEC
Holdings of Great Point Partners LLC in Q4 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
URGNUroGen Pharma Ltd.COM187,843$2.00M0.9%−570,943−75.2%ReducedHistory
OPTNOptiNose, Inc.COM NEW370,269$2.47M1.2%−487,140−56.8%ReducedConverted for a 1-for-15 splitHistory
PMNProMIS Neurosciences Inc.COM2,645,128$2.51M1.2%−145,570−5.2%ReducedHistory
RZLTRezolute, Inc.COM NEW621,894$3.05M1.4%+621,894NewHistory
MREOMereo BioPharma Group plcSPON ADS1,150,000$4.03M1.9%+1,150,000NewHistory
ORKAOruka Therapeutics, Inc.COM228,803$4.44M2.1%−285,856−55.5%ReducedHistory
VYGRVoyager Therapeutics, Inc.COM826,751$4.69M2.2%−133,202−13.9%ReducedHistory
CNTXContext Therapeutics Inc.COM4,683,711$4.92M2.3%−2,251,271−32.5%ReducedHistory
UPBUpstream Bio, Inc.COM300,000$4.93M2.3%+300,000NewHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.25M2.5%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM275,000$6.00M2.8%00.0%UnchangedHistory
MRUSMerus N.V.COM158,092$6.65M3.1%−91,908−36.8%ReducedHistory
JSPRJasper Therapeutics, Inc.COM NEW322,380$6.89M3.2%00.0%UnchangedHistory
AUTLAutolus Therapeutics plcSPON ADS3,009,392$7.07M3.3%+197,437+7.0%AddedHistory
ZURAZura Bio LtdCLASS A ORD SHS3,170,194$7.93M3.7%−93,478−2.9%ReducedHistory
UNCYUnicycive Therapeutics, Inc.COM10,980,000$8.72M4.1%+2,421,000+28.3%AddedHistory
XENEXenon Pharmaceuticals Inc.COM245,272$9.61M4.5%+245,272NewHistory
EOLSEvolus, Inc.COM895,524$9.89M4.7%−274,476−23.5%ReducedHistory
NGNENeurogene Inc.COM442,761$10.1M4.8%−561,530−55.9%ReducedHistory
DVAXDynavax Technologies CorpCOM NEW860,000$11.0M5.2%−466,234−35.2%ReducedHistory
ABVXAbivax S.A.SPONSORED ADS1,648,523$12.1M5.7%−480,250−22.6%ReducedHistory
PLRXPliant Therapeutics, Inc.COM1,055,000$13.9M6.5%−855,121−44.8%ReducedHistory
VRDNViridian Therapeutics, Inc.COM750,000$14.4M6.8%00.0%UnchangedHistory
KALVKalVista Pharmaceuticals, Inc.COM1,787,003$15.1M7.1%+487,500+37.5%AddedHistory
CYTKCytokinetics IncCOM NEW360,000$16.9M8.0%+44,000+13.9%AddedHistory
IONSIonis Pharmaceuticals IncCOM505,007$17.7M8.3%+250,007+98.0%AddedHistory

Sold out since Q3 2024 (7)

Positions held at the end of Q3 2024 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q3 2024
SecurityClassShares in Q3 2024Value in Q3 2024% of portfolio in Q3 2024History
OLMAOlema Pharmaceuticals, Inc.COM1,000,000$11.9M3.6%History
ACLXArcellx, Inc.COMMON STOCK100,000$8.35M2.5%History
OTLKOutlook Therapeutics, Inc.Stock1,293,028$6.90M2.1%History
TCRXTScan Therapeutics, Inc.COM1,016,375$5.06M1.5%History
RNACCartesian Therapeutics, Inc.COM NEW200,000$3.22M1.0%History
VTGNVistagen Therapeutics, Inc.COM674,075$2.03M0.6%History
CLYMClimb Bio, Inc.COM248,168$1.26M0.4%History