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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q4 2022

Holdings as of Dec 31, 2022, filed Feb 14, 2023. Long positions only; changes compare share counts with Q3 2022.

Institution overview
Positions
40
0 vs. Q3 2022
Portfolio value
$483.7M
+$68.4M (+16.5%) vs. Q3 2022
Filed
Feb 14, 2023
SEC
Holdings of Great Point Partners LLC in Q4 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
ANABAnaptysbio, IncCOM15,000$464.9K0.1%+15,000NewHistory
IMUXImmunic, Inc.COM632,184$885.1K0.2%+632,184NewHistory
ALKSAlkermes plc.SHS46,185$1.21M0.2%−461,315−90.9%ReducedHistory
EOLSEvolus, Inc.COM190,329$1.43M0.3%+190,329NewHistory
GBIOGeneration Bio Co.COM1,022,537$4.02M0.8%+197,460+23.9%AddedHistory
Gracell Biotechnologies Inc38406L103SPONSORED ADS1,962,399$4.51M0.9%+1,513,350+337.0%Added–
DTILPrecision Biosciences IncCOM3,801,305$4.52M0.9%+1,090,500+40.2%AddedHistory
URGNUroGen Pharma Ltd.COM560,000$4.97M1.0%−313,424−35.9%ReducedHistory
LRMRLarimar Therapeutics, Inc.COM1,273,635$5.26M1.1%+138,635+12.2%AddedHistory
ALBOAlbireo Pharma, Inc.COM267,283$5.78M1.2%+267,283NewHistory
VERVVerve Therapeutics, Inc.COM300,000$5.80M1.2%+300,000NewHistory
MRTXMirati Therapeutics, Inc.COM133,000$6.03M1.2%+133,000NewHistory
ABOSAcumen Pharmaceuticals, Inc.COM1,116,581$6.03M1.2%−83,419−7.0%ReducedHistory
ICPTIntercept Pharmaceuticals, Inc.COM528,850$6.54M1.4%+423,850+403.7%AddedHistory
ERASErasca, Inc.COM1,538,461$6.63M1.4%+1,538,461NewHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD642,566$6.75M1.4%+150,566+30.6%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM190,000$7.02M1.5%+190,000NewHistory
KALVKalVista Pharmaceuticals, Inc.COM1,055,801$7.14M1.5%−495,918−32.0%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM73,000$9.46M2.0%+73,000NewHistory
CBAYCymaBay Therapeutics, Inc.COM1,550,000$9.72M2.0%+750,561+93.9%AddedHistory
TVTXTravere Therapeutics, Inc.COM475,000$9.99M2.1%−491,108−50.8%ReducedHistory
JBIOJade Biosciences, Inc.COM378,522$11.1M2.3%+378,522NewHistory
PTCTPTC Therapeutics, Inc.COM302,135$11.5M2.4%+302,135NewHistory
DAWNDay One Biopharmaceuticals, Inc.Stock544,451$11.7M2.4%+473,830+670.9%AddedHistory
VKTXViking Therapeutics, Inc.COM1,295,034$12.2M2.5%+1,295,034NewHistory
CINCCinCor Pharma, Inc.COM1,019,153$12.5M2.6%+717,829+238.2%AddedHistory
VTYXVentyx Biosciences, Inc.COM400,695$13.1M2.7%+130,728+48.4%AddedHistory
OPTNOptiNose, Inc.COM7,894,736$14.6M3.0%+7,894,736NewHistory
RAREUltragenyx Pharmaceutical Inc.COM342,300$15.9M3.3%+342,300NewHistory
HRTXHeron Therapeutics, Inc.COM6,360,161$15.9M3.3%+715,000+12.7%AddedHistory
ACRSAclaris Therapeutics, Inc.COM1,019,282$16.1M3.3%00.0%UnchangedHistory
ISEEIVERIC bio, Inc.COM825,000$17.7M3.7%+825,000NewHistory
PNTPOINT Biopharma Global Inc.COM2,541,779$18.5M3.8%−1,019,205−28.6%ReducedHistory
SGENSeagen Inc.COM160,500$20.6M4.3%+84,000+109.8%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD160,000$25.5M5.3%−55,000−25.6%ReducedHistory
PLRXPliant Therapeutics, Inc.COM1,322,870$25.6M5.3%+281,133+27.0%AddedHistory
ALPNAlpine Immune Sciences, Inc.COM3,637,718$26.7M5.5%+189,197+5.5%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,436,569$28.4M5.9%+1,121,569+356.1%AddedHistory
XENEXenon Pharmaceuticals Inc.COM850,000$33.5M6.9%00.0%UnchangedHistory
PCVXVaxcyte, Inc.COM800,000$38.4M7.9%+200,000+33.3%AddedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Great Point Partners LLC in Q4 2022
SecurityClassPutsCalls
NVCRNovoCure LtdORD SHS$17.7M–
RCKTRocket Pharmaceuticals, Inc.COM–$8.83M

Sold out since Q3 2022 (15)

Positions held at the end of Q3 2022 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q3 2022
SecurityClassShares in Q3 2022Value in Q3 2022% of portfolio in Q3 2022History
RLMDRelmada Therapeutics, Inc.COM510,000$18.9M4.5%History
LKFTLakefront Biotherapeutics NVSPON ADR306,411$13.1M3.1%History
BBIOBridgeBio Pharma, Inc.COM1,050,000$10.4M2.5%History
TCDATricida, Inc.COM870,000$9.12M2.2%History
REPLReplimune Group, Inc.COM390,000$6.74M1.6%History
MDGLMadrigal Pharmaceuticals, Inc.COM95,500$6.21M1.5%History
MISTMilestone Pharmaceuticals Inc.COM674,656$6.20M1.5%History
ETNB89bio, Inc.COM955,000$5.53M1.3%History
NGMNGM Biopharmaceuticals IncCOM316,256$4.14M1.0%History
IMCRImmunocore Holdings plcADS78,527$3.69M0.9%History
Pieris Pharmaceuticals Inc720795103COM1,965,449$2.26M0.5%–
DNTHDianthus Therapeutics, Inc.COM1,019,091$1.44M0.3%History
NKTRNektar TherapeuticsCOM447,820$1.43M0.3%History
SYRESpyre Therapeutics, Inc.COM2,500,000$1.31M0.3%History
SLNSilence Therapeutics plcADS68,915$692.0K0.2%History