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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q3 2022

Holdings as of Sep 30, 2022, filed Nov 14, 2022. Long positions only; changes compare share counts with Q2 2022.

Institution overview
Positions
40
+7 vs. Q2 2022
Portfolio value
$415.3M
+$27.2M (+7.0%) vs. Q2 2022
Filed
Nov 14, 2022
SEC
Holdings of Great Point Partners LLC in Q3 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
XENEXenon Pharmaceuticals Inc.COM850,000$30.7M7.4%−254,334−23.0%ReducedHistory
JAZZJazz Pharmaceuticals plcSHS USD215,000$28.7M6.9%+25,000+13.2%AddedHistory
PNTPOINT Biopharma Global Inc.COM3,560,984$27.5M6.6%+1,140,483+47.1%AddedHistory
ALPNAlpine Immune Sciences, Inc.COM3,448,521$24.8M6.0%+2,909,702+540.0%AddedHistory
TVTXTravere Therapeutics, Inc.COM966,108$23.8M5.7%−5,125−0.5%ReducedHistory
HRTXHeron Therapeutics, Inc.COM5,645,161$23.5M5.7%+5,645,161NewHistory
KALVKalVista Pharmaceuticals, Inc.COM1,551,719$22.5M5.4%+21,719+1.4%AddedHistory
PLRXPliant Therapeutics, Inc.COM1,041,737$21.8M5.2%+684,474+191.6%AddedHistory
RLMDRelmada Therapeutics, Inc.COM510,000$18.9M4.5%−190,000−27.1%ReducedHistory
ACRSAclaris Therapeutics, Inc.COM1,019,282$16.0M3.9%−63,718−5.9%ReducedHistory
PCVXVaxcyte, Inc.COM600,000$14.4M3.5%−385,153−39.1%ReducedHistory
LKFTLakefront Biotherapeutics NVSPON ADR306,411$13.1M3.1%−53,589−14.9%ReducedHistory
ABOSAcumen Pharmaceuticals, Inc.COM1,200,000$12.0M2.9%−315,000−20.8%ReducedHistory
ALKSAlkermes plc.SHS507,500$11.3M2.7%+145,864+40.3%AddedHistory
SGENSeagen Inc.COM76,500$10.5M2.5%+76,500NewHistory
BBIOBridgeBio Pharma, Inc.COM1,050,000$10.4M2.5%+1,050,000NewHistory
CINCCinCor Pharma, Inc.COM301,324$9.89M2.4%−367,876−55.0%ReducedHistory
VTYXVentyx Biosciences, Inc.COM269,967$9.43M2.3%−119,256−30.6%ReducedHistory
TCDATricida, Inc.COM870,000$9.12M2.2%−294,763−25.3%ReducedHistory
RAPTRAPT Therapeutics, Inc.COM315,000$7.58M1.8%+315,000NewHistory
URGNUroGen Pharma Ltd.COM873,424$7.27M1.7%00.0%UnchangedHistory
REPLReplimune Group, Inc.COM390,000$6.74M1.6%+390,000NewHistory
MDGLMadrigal Pharmaceuticals, Inc.COM95,500$6.21M1.5%+95,500NewHistory
MISTMilestone Pharmaceuticals Inc.COM674,656$6.20M1.5%+674,656NewHistory
ETNB89bio, Inc.COM955,000$5.53M1.3%−445,000−31.8%ReducedHistory
GBIOGeneration Bio Co.COM825,077$4.38M1.1%+825,077NewHistory
NGMNGM Biopharmaceuticals IncCOM316,256$4.14M1.0%+316,256NewHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD492,000$3.82M0.9%+60,000+13.9%AddedHistory
IMCRImmunocore Holdings plcADS78,527$3.69M0.9%+78,527NewHistory
LRMRLarimar Therapeutics, Inc.COM1,135,000$3.63M0.9%+1,135,000NewHistory
DTILPrecision Biosciences IncCOM2,710,805$3.52M0.8%−3,044,591−52.9%ReducedHistory
CBAYCymaBay Therapeutics, Inc.COM799,439$2.80M0.7%+799,439NewHistory
Pieris Pharmaceuticals Inc720795103COM1,965,449$2.26M0.5%−547,051−21.8%Reduced–
ICPTIntercept Pharmaceuticals, Inc.COM105,000$1.47M0.4%+105,000NewHistory
Gracell Biotechnologies Inc38406L103SPONSORED ADS449,049$1.45M0.3%+449,049New–
DNTHDianthus Therapeutics, Inc.COM1,019,091$1.44M0.3%−150,909−12.9%ReducedHistory
NKTRNektar TherapeuticsCOM447,820$1.43M0.3%−2,702,180−85.8%ReducedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock70,621$1.42M0.3%+70,621NewHistory
SYRESpyre Therapeutics, Inc.COM2,500,000$1.31M0.3%00.0%UnchangedHistory
SLNSilence Therapeutics plcADS68,915$692.0K0.2%−332,534−82.8%ReducedHistory

Sold out since Q2 2022 (8)

Positions held at the end of Q2 2022 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q2 2022
SecurityClassShares in Q2 2022Value in Q2 2022% of portfolio in Q2 2022History
CYTKCytokinetics IncCOM NEW610,000$24.0M6.2%History
KRTXKaruna Therapeutics, Inc.COM149,000$18.9M4.9%History
SRPTSarepta Therapeutics, Inc.COM193,900$14.5M3.7%History
KNSAKiniksa Pharmaceuticals International, plcCOM CL A1,204,028$11.7M3.0%History
ANABAnaptysbio, IncCOM453,118$9.20M2.4%History
NBIXNeurocrine Biosciences IncStock75,000$7.31M1.9%History
Avidity Biosciences, Inc.05370A108COM500,000$7.26M1.9%–
KDNYChinook Therapeutics, Inc.COM336,731$5.89M1.5%History