Skip to main content

Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q3 2022

Holdings as of Sep 30, 2022, filed Nov 14, 2022. Long positions only; changes compare share counts with Q2 2022.

Institution overview
Positions
40
+7 vs. Q2 2022
Portfolio value
$415.3M
+$27.2M (+7.0%) vs. Q2 2022
Filed
Nov 14, 2022
SEC
Holdings of Great Point Partners LLC in Q3 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
SLNSilence Therapeutics plcADS68,915$692.0K0.2%−332,534−82.8%ReducedHistory
SYRESpyre Therapeutics, Inc.COM2,500,000$1.31M0.3%00.0%UnchangedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock70,621$1.42M0.3%+70,621NewHistory
NKTRNektar TherapeuticsCOM447,820$1.43M0.3%−2,702,180−85.8%ReducedHistory
DNTHDianthus Therapeutics, Inc.COM1,019,091$1.44M0.3%−150,909−12.9%ReducedHistory
Gracell Biotechnologies Inc38406L103SPONSORED ADS449,049$1.45M0.3%+449,049New–
ICPTIntercept Pharmaceuticals, Inc.COM105,000$1.47M0.4%+105,000NewHistory
Pieris Pharmaceuticals Inc720795103COM1,965,449$2.26M0.5%−547,051−21.8%Reduced–
CBAYCymaBay Therapeutics, Inc.COM799,439$2.80M0.7%+799,439NewHistory
DTILPrecision Biosciences IncCOM2,710,805$3.52M0.8%−3,044,591−52.9%ReducedHistory
LRMRLarimar Therapeutics, Inc.COM1,135,000$3.63M0.9%+1,135,000NewHistory
IMCRImmunocore Holdings plcADS78,527$3.69M0.9%+78,527NewHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD492,000$3.82M0.9%+60,000+13.9%AddedHistory
NGMNGM Biopharmaceuticals IncCOM316,256$4.14M1.0%+316,256NewHistory
GBIOGeneration Bio Co.COM825,077$4.38M1.1%+825,077NewHistory
ETNB89bio, Inc.COM955,000$5.53M1.3%−445,000−31.8%ReducedHistory
MISTMilestone Pharmaceuticals Inc.COM674,656$6.20M1.5%+674,656NewHistory
MDGLMadrigal Pharmaceuticals, Inc.COM95,500$6.21M1.5%+95,500NewHistory
REPLReplimune Group, Inc.COM390,000$6.74M1.6%+390,000NewHistory
URGNUroGen Pharma Ltd.COM873,424$7.27M1.7%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM315,000$7.58M1.8%+315,000NewHistory
TCDATricida, Inc.COM870,000$9.12M2.2%−294,763−25.3%ReducedHistory
VTYXVentyx Biosciences, Inc.COM269,967$9.43M2.3%−119,256−30.6%ReducedHistory
CINCCinCor Pharma, Inc.COM301,324$9.89M2.4%−367,876−55.0%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,050,000$10.4M2.5%+1,050,000NewHistory
SGENSeagen Inc.COM76,500$10.5M2.5%+76,500NewHistory
ALKSAlkermes plc.SHS507,500$11.3M2.7%+145,864+40.3%AddedHistory
ABOSAcumen Pharmaceuticals, Inc.COM1,200,000$12.0M2.9%−315,000−20.8%ReducedHistory
LKFTLakefront Biotherapeutics NVSPON ADR306,411$13.1M3.1%−53,589−14.9%ReducedHistory
PCVXVaxcyte, Inc.COM600,000$14.4M3.5%−385,153−39.1%ReducedHistory
ACRSAclaris Therapeutics, Inc.COM1,019,282$16.0M3.9%−63,718−5.9%ReducedHistory
RLMDRelmada Therapeutics, Inc.COM510,000$18.9M4.5%−190,000−27.1%ReducedHistory
PLRXPliant Therapeutics, Inc.COM1,041,737$21.8M5.2%+684,474+191.6%AddedHistory
KALVKalVista Pharmaceuticals, Inc.COM1,551,719$22.5M5.4%+21,719+1.4%AddedHistory
HRTXHeron Therapeutics, Inc.COM5,645,161$23.5M5.7%+5,645,161NewHistory
TVTXTravere Therapeutics, Inc.COM966,108$23.8M5.7%−5,125−0.5%ReducedHistory
ALPNAlpine Immune Sciences, Inc.COM3,448,521$24.8M6.0%+2,909,702+540.0%AddedHistory
PNTPOINT Biopharma Global Inc.COM3,560,984$27.5M6.6%+1,140,483+47.1%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD215,000$28.7M6.9%+25,000+13.2%AddedHistory
XENEXenon Pharmaceuticals Inc.COM850,000$30.7M7.4%−254,334−23.0%ReducedHistory

Sold out since Q2 2022 (8)

Positions held at the end of Q2 2022 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q2 2022
SecurityClassShares in Q2 2022Value in Q2 2022% of portfolio in Q2 2022History
CYTKCytokinetics IncCOM NEW610,000$24.0M6.2%History
KRTXKaruna Therapeutics, Inc.COM149,000$18.9M4.9%History
SRPTSarepta Therapeutics, Inc.COM193,900$14.5M3.7%History
KNSAKiniksa Pharmaceuticals International, plcCOM CL A1,204,028$11.7M3.0%History
ANABAnaptysbio, IncCOM453,118$9.20M2.4%History
NBIXNeurocrine Biosciences IncStock75,000$7.31M1.9%History
Avidity Biosciences, Inc.05370A108COM500,000$7.26M1.9%–
KDNYChinook Therapeutics, Inc.COM336,731$5.89M1.5%History