Baker Bros. Advisors LP
- SEC CIK
- 0001263508
- Latest filing
- Aug 14, 2026
Holdings in Q2 2024
Holdings as of Jun 30, 2024, filed Aug 14, 2024. Long positions only; changes compare share counts with Q1 2024.
- Positions
- 95
- +8 vs. Q1 2024
- Portfolio value
- $7.83B
- −$146.6M (−1.8%) vs. Q1 2024
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| INCYIncyte Corp | COM | 30,738,524 | $1.86B | 23.8% | −5,441,141−15.0% | Reduced | History |
| ONCBeOne Medicines Ltd. | ADR | 10,568,897 | $1.51B | 19.3% | 00.0% | Unchanged | History |
| ACADAcadia Pharmaceuticals Inc | COM | 42,877,916 | $696.8M | 8.9% | +13,3040.0% | Added | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 1,974,590 | $553.2M | 7.1% | +4,792+0.2% | Added | History |
| RVMDRevolution Medicines, Inc. | COM | 7,569,090 | $293.8M | 3.8% | +19,841+0.3% | Added | History |
| RYTMRhythm Pharmaceuticals, Inc. | COM | 6,398,365 | $262.7M | 3.4% | 00.0% | Unchanged | History |
| INSMINSMED Inc | COM PAR $.01 | 3,576,038 | $239.6M | 3.1% | +3,233,038+942.6% | Added | History |
| BCYCBicycle Therapeutics PLC | SPONSORED ADS | 9,399,960 | $190.3M | 2.4% | +4,457,137+90.2% | Added | History |
| SMMTSummit Therapeutics Inc. | COM | 23,222,222 | $181.1M | 2.3% | +23,222,222 | New | History |
| KYMRKymera Therapeutics, Inc. | COM | 5,995,928 | $179.0M | 2.3% | 00.0% | Unchanged | History |
| EWTXEdgewise Therapeutics, Inc. | COM | 5,840,059 | $105.2M | 1.3% | 00.0% | Unchanged | History |
| ALKSAlkermes plc. | SHS | 4,181,751 | $100.8M | 1.3% | +4,181,751 | New | History |
| INSMED Inc457669AB5 | NOTE 0.750% 6/0 | – | $90.4M | 1.2% | – | New | – |
| REPLReplimune Group, Inc. | COM | 10,045,336 | $90.4M | 1.2% | +500,000+5.2% | Added | History |
| DNLIDenali Therapeutics Inc. | COM | 3,731,695 | $86.6M | 1.1% | 00.0% | Unchanged | History |
| ABCLAbCellera Biologics Inc. | COM | 27,525,640 | $81.5M | 1.0% | 00.0% | Unchanged | History |
| NRIXNurix Therapeutics, Inc. | COM | 3,882,125 | $81.0M | 1.0% | 00.0% | Unchanged | History |
| IMTXImmatics N.V. | SHS | 6,443,398 | $74.9M | 1.0% | 00.0% | Unchanged | History |
| TRDAEntrada Therapeutics, Inc. | COM | 4,865,819 | $69.3M | 0.9% | 00.0% | Unchanged | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 1,466,547 | $60.3M | 0.8% | 00.0% | Unchanged | History |
| STOKStoke Therapeutics, Inc. | COM | 4,368,443 | $59.0M | 0.8% | +1,000,000+29.7% | Added | History |
| INSMED Inc457669AA7 | NOTE 1.750% 1/1 | – | $56.2M | 0.7% | – | New | – |
| KNSAKiniksa Pharmaceuticals International, plc | ORD SHS CL A | 2,818,323 | $52.6M | 0.7% | +8,746+0.3% | Added | History |
| IMCRImmunocore Holdings plc | ADS | 1,515,318 | $51.4M | 0.7% | 00.0% | Unchanged | History |
| ARGXArgenx SE | SPONSORED ADR | 111,904 | $48.1M | 0.6% | −39,311−26.0% | Reduced | History |
| KODKodiak Sciences Inc. | COM | 17,310,490 | $40.7M | 0.5% | 00.0% | Unchanged | History |
| XENEXenon Pharmaceuticals Inc. | COM | 993,679 | $38.7M | 0.5% | 00.0% | Unchanged | History |
| PRLDPrelude Therapeutics Inc | COM | 10,123,824 | $38.6M | 0.5% | 00.0% | Unchanged | History |
| IDYAIDEAYA Biosciences, Inc. | COM | 1,062,123 | $37.3M | 0.5% | 00.0% | Unchanged | History |
| CERSCerus Corp | COM | 19,477,339 | $34.3M | 0.4% | 00.0% | Unchanged | History |
| SERASera Prognostics, Inc. | CLASS A COM | 5,434,399 | $32.2M | 0.4% | 00.0% | Unchanged | History |
| KRYSKrystal Biotech, Inc. | COM | 169,934 | $31.2M | 0.4% | 00.0% | Unchanged | History |
| CELCCelcuity Inc. | COM | 1,874,978 | $30.7M | 0.4% | +322,500+20.8% | Added | History |
| ROIVRoivant Sciences Ltd. | SHS | 2,798,716 | $29.6M | 0.4% | −4,615,118−62.3% | Reduced | History |
| IGMSIGM Biosciences, Inc. | COM | 4,090,316 | $28.1M | 0.4% | +1,9940.0% | Added | History |
| CERECerevel Therapeutics Holdings, Inc. | COM | 683,588 | $28.0M | 0.4% | −916,412−57.3% | Reduced | History |
| AKROAkero Therapeutics, Inc. | COM | 1,097,082 | $25.7M | 0.3% | −1,616,123−59.6% | Reduced | History |
| DYNDyne Therapeutics, Inc. | COM | 672,096 | $23.7M | 0.3% | +387,096+135.8% | Added | History |
| ALMSAlumis Inc. | COM | 1,562,500 | $20.8M | 0.3% | +1,562,500 | New | History |
| GLUEMonte Rosa Therapeutics, Inc. | COM | 4,916,095 | $18.4M | 0.2% | 00.0% | Unchanged | History |
| MRUSMerus N.V. | COM | 300,000 | $17.8M | 0.2% | +300,000 | New | History |
| NGNENeurogene Inc. | COM | 456,015 | $16.6M | 0.2% | 00.0% | Unchanged | History |
| TCRXTScan Therapeutics, Inc. | COM | 2,784,792 | $16.3M | 0.2% | 00.0% | Unchanged | History |
| SANASana Biotechnology, Inc. | COM | 2,380,949 | $13.0M | 0.2% | 00.0% | Unchanged | History |
| IMVTImmunovant, Inc. | COM | 464,718 | $12.3M | 0.2% | +39,709+9.3% | Added | History |
| XNCRXencor Inc | COM | 545,431 | $10.3M | 0.1% | 00.0% | Unchanged | History |
| NMRANeumora Therapeutics, Inc. | COM | 1,034,600 | $10.2M | 0.1% | +400,749+63.2% | Added | History |
| FATEFate Therapeutics Inc | COM | 2,997,772 | $9.83M | 0.1% | +1,179,591+64.9% | Added | History |
| TSVT2seventy bio, Inc. | COMMON STOCK | 2,497,526 | $9.62M | 0.1% | 00.0% | Unchanged | History |
| BMEABiomea Fusion, Inc. | COM | 2,108,949 | $9.49M | 0.1% | 00.0% | Unchanged | History |
| CLDXCelldex Therapeutics, Inc. | COM NEW | 247,644 | $9.17M | 0.1% | 00.0% | Unchanged | History |
| TSHATaysha Gene Therapies, Inc. | COM SHS | 4,004,756 | $8.97M | 0.1% | 00.0% | Unchanged | History |
| LONALeonaBio, Inc. | COM | 3,153,807 | $8.36M | 0.1% | 00.0% | Unchanged | History |
| VERVVerve Therapeutics, Inc. | COM | 1,691,530 | $8.25M | 0.1% | 00.0% | Unchanged | History |
| RLAYRelay Therapeutics, Inc. | COM | 1,160,117 | $7.56M | 0.1% | 00.0% | Unchanged | History |
| MIRMMirum Pharmaceuticals, Inc. | COM | 190,476 | $6.51M | 0.1% | 00.0% | Unchanged | History |
| TNGXTango Therapeutics, Inc. | COM | 750,000 | $6.43M | 0.1% | 00.0% | Unchanged | History |
| KALAKALA BIO, Inc. | COMM STK | 891,335 | $6.32M | 0.1% | +624,722+234.3% | Added | History |
| DBVTDBV Technologies S.A. | SPONSORED ADR | 7,307,131 | $5.85M | 0.1% | +7,307,131 | New | History |
| DSGNDesign Therapeutics, Inc. | COM | 1,695,294 | $5.68M | 0.1% | +33,174+2.0% | Added | History |
| CTNMContineum Therapeutics, Inc. | CL A | 312,500 | $5.50M | 0.1% | +312,500 | New | History |
| PRAXPraxis Precision Medicines, Inc. | COM NEW | 131,533 | $5.44M | 0.1% | 00.0% | Unchanged | History |
| CRSPCRISPR Therapeutics AG | NAMEN AKT | 100,000 | $5.40M | 0.1% | +100,000 | New | History |
| PRMEPrime Medicine, Inc. | COM | 1,028,466 | $5.29M | 0.1% | 00.0% | Unchanged | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 549,212 | $4.96M | 0.1% | +549,212 | New | History |
| HOOKHOOKIPA Pharma Inc. | COM | 8,128,151 | $4.81M | 0.1% | +8,128,151 | New | History |
| SGMTSagimet Biosciences Inc. | COM SER A | 1,381,898 | $4.73M | 0.1% | 00.0% | Unchanged | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 103,927 | $4.65M | 0.1% | +103,927 | New | History |
| TLISTalis Biomedical Corp | COM | 508,323 | $4.40M | 0.1% | 00.0% | Unchanged | History |
| ALECAlector, Inc. | COM | 927,264 | $4.21M | 0.1% | +927,264 | New | History |
| CYVNYOpthea Ltd | SPONSORED ADS | 2,173,622 | $4.20M | 0.1% | −4,204−0.2% | Reduced | History |
| SKYESkye Bioscience, Inc. | COM NEW | 500,000 | $4.00M | 0.1% | +500,000 | New | History |
| PCVXVaxcyte, Inc. | COM | 48,885 | $3.69M | <0.1% | 00.0% | Unchanged | History |
| ARCTArcturus Therapeutics Holdings Inc. | COM | 151,329 | $3.68M | <0.1% | +151,329 | New | History |
| GBIOGeneration Bio Co. | COM | 1,206,957 | $3.40M | <0.1% | +835,738+225.1% | Added | History |
| ELVNEnliven Therapeutics, Inc. | COM | 114,833 | $2.68M | <0.1% | 00.0% | Unchanged | History |
| CYPHCypherpunk Technologies Inc. | COM NEW | 1,172,175 | $2.30M | <0.1% | 00.0% | Unchanged | History |
| ADAPYAdaptimmune Therapeutics PLC | SPONDS ADR | 2,343,695 | $2.28M | <0.1% | −8,443,327−78.3% | Reduced | History |
| MRSNMersana Therapeutics, Inc. | COM | 1,086,115 | $2.18M | <0.1% | 00.0% | Unchanged | History |
| IPSCCentury Therapeutics, Inc. | COM | 797,460 | $2.03M | <0.1% | 00.0% | Unchanged | History |
| NAMSNewAmsterdam Pharma Co N.V. | ORDINARY SHARES | 96,827 | $1.86M | <0.1% | 00.0% | Unchanged | History |
| SAGESage Therapeutics, Inc. | COM | 171,026 | $1.86M | <0.1% | −236,191−58.0% | Reduced | History |
| VTVTvTv Therapeutics Inc. | CL A NEW | 97,314 | $1.72M | <0.1% | 00.0% | Unchanged | History |
| CMPXCompass Therapeutics, Inc. | COM | 1,557,630 | $1.56M | <0.1% | 00.0% | Unchanged | History |
| TARAProtara Therapeutics, Inc. | COM STK | 536,832 | $1.12M | <0.1% | +337,161+168.9% | Added | History |
| JBIOJade Biosciences, Inc. | COM | 628,939 | $1.04M | <0.1% | −1,051,578−62.6% | Reduced | History |
| PFEPfizer Inc | Stock | 35,000 | $979.3K | <0.1% | 00.0% | Unchanged | History |
| Achilles Therapeutics PLC00449L102 | SPONSORED ADS | 1,108,767 | $903.6K | <0.1% | −100,008−8.3% | Reduced | – |
| ALGSAligos Therapeutics, Inc. | COM | 2,076,400 | $726.7K | <0.1% | 00.0% | Unchanged | History |
| PMVPPMV Pharmaceuticals, Inc. | COM | 322,024 | $521.7K | <0.1% | 00.0% | Unchanged | History |
| BCRXBiocryst Pharmaceuticals Inc | COM | 75,778 | $468.3K | <0.1% | −10,050,398−99.3% | Reduced | History |
| ACRVAcrivon Therapeutics, Inc. | COMMON STOCK | 52,885 | $306.7K | <0.1% | 00.0% | Unchanged | History |
| FHTXFoghorn Therapeutics Inc. | COM | 45,027 | $258.9K | <0.1% | 00.0% | Unchanged | History |
| TYRATyra Biosciences, Inc. | COM | 10,607 | $169.6K | <0.1% | 00.0% | Unchanged | History |
| Surrozen, Inc.86889P117 | *W EXP 08/01/203 | 833,333 | $13.8K | <0.1% | 00.0% | Unchanged | – |
Sold out since Q1 2024 (7)
Positions held at the end of Q1 2024 that are gone from this filing.
| Security | Class | Shares in Q1 2024 | Value in Q1 2024 | % of portfolio in Q1 2024 | History |
|---|---|---|---|---|---|
| DBVTDBV Technologies S.A. | SPONSORED ADR | 14,614,264 | $10.9M | 0.1% | History |
| HOOKHOOKIPA Pharma Inc. | COM | 8,128,151 | $5.79M | 0.1% | History |
| ALPNAlpine Immune Sciences, Inc. | COM | 81,578 | $3.23M | <0.1% | History |
| FDMT4D Molecular Therapeutics, Inc. | COM | 100,000 | $3.19M | <0.1% | History |
| MURAMural Oncology plc | ORD SHS | 222,503 | $1.09M | <0.1% | History |
| CABACabaletta Bio, Inc. | COM | 13,331 | $227.4K | <0.1% | History |
| CATXPerspective Therapeutics, Inc. | COM | 149,787 | $178.2K | <0.1% | History |