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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q4 2022

Holdings as of Dec 31, 2022, filed Feb 14, 2023. Long positions only; changes compare share counts with Q3 2022.

Institution overview
Positions
94
−21 vs. Q3 2022
Portfolio value
$3.47B
+$29.3M (+0.9%) vs. Q3 2022
Filed
Feb 14, 2023
SEC
Holdings of Perceptive Advisors LLC in Q4 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$9.18K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$31.3K<0.1%00.0%Unchanged–
EQRx, Inc.26886C115*W EXP 12/17/202250,000$67.0K<0.1%00.0%Unchanged–
MOTSMotus GI Holdings, Inc.COM NEW90,027$75.6K<0.1%00.0%UnchangedHistory
TARAProtara Therapeutics, Inc.COM STK290,051$777.3K<0.1%00.0%UnchangedHistory
PEARPear Therapeutics, Inc.CLASS A COM900,548$1.06M<0.1%00.0%UnchangedHistory
NVRONevro CorpCOM30,000$1.19M<0.1%−120,000−80.0%ReducedHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$1.39M<0.1%00.0%UnchangedHistory
DRIODarioHealth Corp.COM NEW327,869$1.40M<0.1%00.0%UnchangedHistory
ABOSAcumen Pharmaceuticals, Inc.COM347,450$1.88M0.1%−52,550−13.1%ReducedHistory
TVTXTravere Therapeutics, Inc.COM90,748$1.91M0.1%00.0%UnchangedHistory
PRVAPrivia Health Group, Inc.COM90,000$2.04M0.1%+90,000NewHistory
ATNXAthenex, Inc.COM15,532,467$2.29M0.1%00.0%UnchangedHistory
IMVTImmunovant, Inc.COM150,000$2.66M0.1%+150,000NewHistory
PRCTPROCEPT BioRobotics CorpCOM64,537$2.68M0.1%−199,183−75.5%ReducedHistory
KRONKronos Bio, Inc.COM1,752,745$2.84M0.1%−403,406−18.7%ReducedHistory
CABACabaletta Bio, Inc.COM317,454$2.94M0.1%+317,454NewHistory
CYPHCypherpunk Technologies Inc.COM6,726,496$3.03M0.1%−745,652−10.0%ReducedHistory
PNTPOINT Biopharma Global Inc.COM500,000$3.65M0.1%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM494,403$3.76M0.1%00.0%UnchangedHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.77M0.1%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$3.89M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$3.99M0.1%00.0%UnchangedHistory
CBAYCymaBay Therapeutics, Inc.COM708,993$4.45M0.1%+708,993NewHistory
NTRANatera, Inc.COM130,000$5.22M0.2%+10,000+8.3%AddedHistory
ACRSAclaris Therapeutics, Inc.COM341,239$5.37M0.2%00.0%UnchangedHistory
PENPenumbra IncCOM25,400$5.65M0.2%+25,400NewHistory
ISOIsoPlexis CorpCOM4,095,498$6.35M0.2%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM3,282,275$6.60M0.2%−253,999−7.2%ReducedHistory
HLVXHilleVax, Inc.COM406,024$6.79M0.2%−358,883−46.9%ReducedHistory
SCPHscPharmaceuticals Inc.COM952,380$6.83M0.2%+952,380NewHistory
LABPLandos Biopharma, Inc.COM14,869,915$7.43M0.2%00.0%UnchangedHistory
DICEDICE Therapeutics, Inc.COM293,362$9.15M0.3%−394,062−57.3%ReducedHistory
MORFMorphic Holding, Inc.COM363,197$9.72M0.3%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW40,000$10.6M0.3%+40,000NewHistory
CMAXCareMax, Inc.COM CL A3,129,195$11.4M0.3%−265,744−7.8%ReducedHistory
LRMRLarimar Therapeutics, Inc.COM2,860,000$11.8M0.3%00.0%UnchangedHistory
NBIXNeurocrine Biosciences IncStock100,050$11.9M0.3%00.0%UnchangedHistory
ISEEIVERIC bio, Inc.COM587,400$12.6M0.4%−446,769−43.2%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,697,033$12.9M0.4%00.0%UnchangedHistory
AORTArtivion, Inc.COM1,085,860$13.2M0.4%−118,369−9.8%ReducedHistory
CTKBCytek Biosciences, Inc.COM1,289,534$13.2M0.4%00.0%UnchangedHistory
RVNCRevance Therapeutics, Inc.COM729,097$13.5M0.4%−79,574−9.8%ReducedHistory
AXGNAxogen, Inc.COM1,388,126$13.9M0.4%+438,500+46.2%AddedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$13.9M0.4%00.0%UnchangedHistory
PRTAProthena Corp Public Ltd CoSHS237,646$14.3M0.4%+7,646+3.3%AddedHistory
LONALeonaBio, Inc.COM4,797,278$15.2M0.4%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS1,981,570$15.8M0.5%+1,981,570NewHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$16.4M0.5%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$18.8M0.5%+2,601,763+291.0%AddedConverted for a 1-for-15 splitHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$19.0M0.5%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM350,525$19.2M0.6%−79,475−18.5%ReducedHistory
Rain Oncology Inc.75082Q105COM2,483,619$19.9M0.6%00.0%Unchanged–
VBIVVBI Vaccines Inc/BCCOM NEW52,335,002$20.4M0.6%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,078,204$21.1M0.6%+578,204+115.6%AddedHistory
HRMYHarmony Biosciences Holdings, Inc.COM411,804$22.7M0.7%00.0%UnchangedHistory
OMOutset Medical, Inc.COM1,089,427$28.1M0.8%−79,203−6.8%ReducedHistory
LYRALyra Therapeutics, Inc.COM9,146,730$28.7M0.8%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$29.0M0.8%00.0%UnchangedHistory
IMTXImmatics N.V.SHS3,491,500$30.4M0.9%+991,500+39.7%AddedHistory
CINCCinCor Pharma, Inc.COM2,576,325$31.7M0.9%−730,324−22.1%ReducedHistory
ATXSAstria Therapeutics, Inc.COM2,189,462$32.6M0.9%+908,265+70.9%AddedHistory
ESTAEstablishment Labs Holdings Inc.COM497,857$32.7M0.9%−80,396−13.9%ReducedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$34.7M1.0%+3,007,858NewHistory
ZYMEZymeworks Inc.COM4,511,275$35.5M1.0%+111,176+2.5%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,798,955$35.6M1.0%+85,821+5.0%AddedHistory
VRDNViridian Therapeutics, Inc.COM1,220,575$35.7M1.0%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM3,207,441$37.1M1.1%00.0%UnchangedHistory
ALBOAlbireo Pharma, Inc.COM1,757,160$38.0M1.1%−602,979−25.5%ReducedHistory
VERUVeru Inc.COM7,858,011$41.5M1.2%+3,965,011+101.8%AddedHistory
TMCITreace Medical Concepts, Inc.COM1,946,403$44.7M1.3%+344,424+21.5%AddedHistory
MGTXMeiraGTx Holdings plcCOM6,963,277$45.4M1.3%00.0%UnchangedHistory
ADMAAdma Biologics, Inc.COM11,900,255$46.2M1.3%+966,868+8.8%AddedHistory
BMRNBiomarin Pharmaceutical IncCOM506,481$52.4M1.5%+170,000+50.5%AddedHistory
PCVXVaxcyte, Inc.COM1,170,000$56.1M1.6%+1,170,000NewHistory
IOVAIovance Biotherapeutics, Inc.COM9,971,780$63.7M1.8%−276,844−2.7%ReducedHistory
NUVLNuvalent, Inc.COM2,255,007$67.2M1.9%+600,000+36.3%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM2,617,691$68.1M2.0%−852,872−24.6%ReducedHistory
Bellus Health Inc New07987C204COM NEW8,891,027$73.1M2.1%−1,356,046−13.2%Reduced–
CRNXCrinetics Pharmaceuticals, Inc.COM4,039,276$73.9M2.1%−1,281,756−24.1%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM1,921,273$75.8M2.2%−201,262−9.5%ReducedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$79.0M2.3%00.0%UnchangedHistory
ACLXArcellx, Inc.COMMON STOCK2,598,305$80.5M2.3%+132,900+5.4%AddedHistory
INBXInhibrx Biosciences, Inc.COM3,313,783$81.7M2.4%+425,923+14.7%AddedHistory
SRPTSarepta Therapeutics, Inc.COM649,250$84.1M2.4%+396,250+156.6%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$94.4M2.7%00.0%UnchangedHistory
MRTXMirati Therapeutics, Inc.COM2,191,425$99.3M2.9%−593,371−21.3%ReducedHistory
HZNPHorizon Therapeutics Public Ltd CoSHS960,000$109.2M3.1%+960,000NewHistory
VRNAVerona Pharma plcSPONSORED ADS4,880,719$127.5M3.7%−166,545−3.3%ReducedHistory
RXDXPrometheus Biosciences, Inc.COM1,212,694$133.4M3.8%−255,818−17.4%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM6,511,727$205.4M5.9%00.0%UnchangedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM731,932$212.4M6.1%+400,909+121.1%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM6,088,333$225.0M6.5%+616,300+11.3%AddedHistory
FOLDAmicus Therapeutics, Inc.COM27,642,917$337.5M9.7%+270,000+1.0%AddedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q4 2022
SecurityClassPutsCalls
MDGLMadrigal Pharmaceuticals, Inc.COM$87.1M–
FLNAFilana Therapeutics, Inc.COM$4.43M–

Sold out since Q3 2022 (32)

Positions held at the end of Q3 2022 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q3 2022
SecurityClassShares in Q3 2022Value in Q3 2022% of portfolio in Q3 2022History
GBTGlobal Blood Therapeutics, Inc.COM2,322,247$158.1M4.6%History
RLMDRelmada Therapeutics, Inc.COM2,383,478$88.2M2.6%History
Travere Therapeutics, Inc.89422GAA5NOTE 2.250% 3/0–$46.0M1.3%–
SGENSeagen Inc.COM316,544$43.3M1.3%History
EWEdwards Lifesciences CorpStock330,000$27.3M0.8%History
APLSApellis Pharmaceuticals, Inc.COM366,400$25.0M0.7%History
RCUSArcus Biosciences, Inc.COM666,477$17.4M0.5%History
CHRSCoherus Oncology, Inc.COM1,667,123$16.0M0.5%History
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$14.4M0.4%History
ChemoCentryx, Inc.16383L106COM192,680$9.95M0.3%–
CCCCC4 Therapeutics, Inc.COM STK766,231$6.72M0.2%History
RVMDRevolution Medicines, Inc.COM310,500$6.12M0.2%History
NARIInari Medical, Inc.Stock70,000$5.08M0.1%History
WGSGeneDx Holdings Corp.COMMON STOCK5,000,000$4.39M0.1%History
CTICCti Biopharma CorpCOM735,165$4.28M0.1%History
HCATHealth Catalyst, Inc.COM389,962$3.78M0.1%History
Coherus Biosciences Inc19249HAB9NOTE 1.500% 4/1–$3.59M0.1%–
YMABY-mAbs Therapeutics, Inc.COM212,018$3.06M0.1%History
PYXSPyxis Oncology, Inc.COMMON STOCK1,528,812$3.01M0.1%History
ABSIAbsci CorpCOM894,346$2.80M0.1%History
PSTXPoseida Therapeutics, Inc.COM750,000$2.65M0.1%History
RETAReata Pharmaceuticals IncCL A100,000$2.51M0.1%History
QTNTQuotient LtdSHS16,200,818$2.43M0.1%History
SNCEScience 37 Holdings, Inc.COM1,500,000$2.42M0.1%History
FULCFulcrum Therapeutics, Inc.COM294,118$2.38M0.1%History
HYPRHyperfine, Inc.COM CL A927,388$751.0K<0.1%History
SONXSonendo, Inc.COM612,204$655.0K<0.1%History
PRVBProvention Bio, Inc.COM110,728$498.0K<0.1%History
ICVXIcosavax, Inc.COM93,591$296.0K<0.1%History
AGRXAgile Therapeutics IncCOM NEW532,361$158.0K<0.1%History
NEPTFNeptune Wellness Solutions Inc.COM NEW57,142$87.0K<0.1%History
SRZNSurrozen, Inc.COM6,017$12.0K<0.1%History