OrbiMed Advisors LLC
- SEC CIK
- 0001055951
- Latest filing
- Aug 14, 2026
Holdings in Q1 2026
Holdings as of Mar 31, 2026, filed May 15, 2026. Long positions only; changes compare share counts with Q4 2025.
- Positions
- 107
- +2 vs. Q4 2025
- Portfolio value
- $4.40B
- −$485.6M (−9.9%) vs. Q4 2025
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| AZNAstraZeneca PLC | ADR | 670,200 | $132.2M | 3.0% | +670,200 | New | History |
| SIONSionna Therapeutics, Inc. | COM | 3,530,702 | $141.5M | 3.2% | −30,953−0.9% | Reduced | History |
| BSXBoston Scientific Corp | Stock | 2,382,100 | $149.5M | 3.4% | −37,200−1.5% | Reduced | History |
| LLYEli Lilly & Co | Stock | 236,800 | $217.8M | 4.9% | −64,400−21.4% | Reduced | History |
| ELVNEnliven Therapeutics, Inc. | COM | 7,959,538 | $312.0M | 7.1% | 00.0% | Unchanged | History |
| EWTXEdgewise Therapeutics, Inc. | COM | 15,518,492 | $488.8M | 11.1% | 00.0% | Unchanged | History |
| SVASinovac Biotech Ltd | SHS | 2,718,735 | – | – | 00.0% | Unchanged | History |
Options (5)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
Sold out since Q4 2025 (20)
Positions held at the end of Q4 2025 that are gone from this filing.
| Security | Class | Shares in Q4 2025 | Value in Q4 2025 | % of portfolio in Q4 2025 | History |
|---|---|---|---|---|---|
| TERNTerns Pharmaceuticals, Inc. | COM | 2,153,300 | $87.0M | 1.8% | History |
| APLSApellis Pharmaceuticals, Inc. | COM | 2,429,868 | $61.0M | 1.2% | History |
| CICigna Group | Stock | 205,000 | $56.4M | 1.2% | History |
| RAPTRAPT Therapeutics, Inc. | COM NEW | 1,642,891 | $55.6M | 1.1% | History |
| UTHRUnited Therapeutics Corp | COM | 105,200 | $51.3M | 1.0% | History |
| ROIVRoivant Sciences Ltd. | SHS | 2,190,907 | $47.5M | 1.0% | History |
| Avidity Biosciences, Inc.05370A108 | COM | 619,530 | $44.7M | 0.9% | – |
| NBIXNeurocrine Biosciences Inc | Stock | 314,240 | $44.6M | 0.9% | History |
| EXASExact Sciences Corp | COM | 351,716 | $35.7M | 0.7% | History |
| BRKRBruker Corp | COM | 555,789 | $26.2M | 0.5% | History |
| CTMXCytomX Therapeutics, Inc. | COM | 3,525,650 | $15.0M | 0.3% | History |
| VIRVir Biotechnology, Inc. | COM | 2,380,715 | $14.4M | 0.3% | History |
| TARSTarsus Pharmaceuticals, Inc. | COM | 154,400 | $12.6M | 0.3% | History |
| FOLDAmicus Therapeutics, Inc. | COM | 729,900 | $10.4M | 0.2% | History |
| RPTXRepare Therapeutics Inc. | COM | 3,322,488 | $8.64M | 0.2% | History |
| CELCCelcuity Inc. | COM | 85,664 | $8.54M | 0.2% | History |
| PMVPPMV Pharmaceuticals, Inc. | COM | 4,975,291 | $6.22M | 0.1% | History |
| INSMINSMED Inc | COM PAR $.01 | 25,400 | $4.42M | 0.1% | History |
| OCULOcular Therapeutix, Inc | COM | 157,300 | $1.91M | <0.1% | History |
| MPLTMapLight Therapeutics, Inc. | COM | 56,000 | $952.0K | <0.1% | History |